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The SIDER Side Effect Resource represents an effort to aggregate dispersed public information on side effects. To our knowledge, no such resource exist in machine-readable form despite the importance of research on drugs and their effects. The creation of this resource was motivated by the many requests for data that we received related to our paper (Campillos, Kuhn et al., Science, 2008, 321(5886):263-6.) on the utilization of side effects for drug target prediction. Inclusion of side effects as readouts for drug treatment should have many applications and we hope to be able to enhance the respective research with this resource.

View papers citing SIDER on Google Scholar.

Citing SIDER

Kuhn M, Letunic I, Jensen LJ, Bork P.
The SIDER database of drugs and side effects.
Nucleic Acids Res. 2015 Oct 19. doi: 10.1093/nar/gkv1075
Kuhn M, Campillos M, Letunic I, Jensen LJ, Bork P.
A side effect resource to capture phenotypic effects of drugs.
Mol Syst Biol. 2010;6:343. Epub 2010 Jan 19.

Related references

Campillos M*, Kuhn M*, Gavin AC, Jensen LJ, Bork P.
Drug target identification using side-effect similarity.
Science. 2008 Jul 11;321(5886):263-6.
Kuhn M*, Campillos M*, González P*, Jensen LJ*, Bork P*.
Large-scale prediction of drug-target relationships.
FEBS Lett. 2008 Apr 9;582(8):1283-90. Epub 2008 Feb 20.
Kuhn M, von Mering C, Campillos M, Jensen LJ, Bork P.
STITCH: interaction networks of chemicals and proteins.
Nucleic Acids Res. 2008 Jan;36(Database issue):D684-8. Epub 2007 Dec 15.
Kuhn M, Szklarczyk D, Franceschini A, Campillos M, von Mering C, Jensen LJ, Beyer A, Bork P.
STITCH 2: an interaction network database for small molecules and proteins.
Nucleic Acids Res. 2010 Jan;38(Database issue):D552-6. Epub 2009 Nov 6.
Kuhn M, Al Banchaabouchi M, Campillos M, Jensen LJ, Gross C, Gavin AC, Bork P.
Systematic identification of proteins that elicit drug side effects.
Mol Syst Biol. 2013 Apr 30;9:663.