Side effect information for Tetrahydrobiopterin

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: A16AX07

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Side effect	Data for drug	Placebo	Labels
			1	2	3	4	5
Headache	14.9%	13.6%	x	x	x	x	x
Nervous system disorder	14.9%	13.6%	x	x	x	x	x
Infection	12.2%	23.7%		x	x
Upper respiratory tract infection	12.2%	23.7%		x	x	x	x
Infestation NOS	12.2%	23.7%		x	x
Rhinorrhoea	10.8%	0%	x	x	x	x	x
Pharyngolaryngeal pain	9.46%	1.69%	x	x	x	x	x
Diarrhoea	8.11%	5.08%	x	x	x	x	x
Gastrointestinal disorder	8.11%	5.08%	x	x	x
Vomiting	postmarketing, 8.11%	6.78%	x	x	x	x	x
Cough	6.76%	5.08%	x	x	x	x	x
Body temperature increased	6.76%	6.78%		x	x	x
Contusion	5.41%	1.69%		x	x	x
Unspecified disorder of skin and subcutaneous tissue	5.41%	6.78%		x	x
Nasal congestion	4.05%	0%	x	x	x	x	x
Abdominal pain	postmarketing, 5.41%	8.47%	x	x	x	x	x
Anaphylactic shock	postmarketing						x
Dyspepsia	postmarketing						x
Rash	postmarketing, 5.41%	6.78%	x	x	x	x	x
Gastritis	postmarketing					x	x
Hypersensitivity	postmarketing		x	x	x		x
Nausea	postmarketing					x	x
Pharyngitis	postmarketing						x
Convulsion	postmarketing			x	x	x	x
Oesophageal pain	postmarketing						x
Hyperkinesia	postmarketing						x
Tetrahydrobiopterin deficiency	postmarketing			x	x
Oropharyngeal pain	postmarketing						x
Arthralgia						x	x
Cardiovascular disorder						x	x
Dizziness						x	x
Gastrointestinal haemorrhage						x	x
Irritability						x	x
Mediastinal disorder			x
Myocardial infarction						x	x
Neutropenia						x
Polyuria						x	x
Spinal cord injury						x
Streptococcal infection						x
Urinary tract infection						x
Agitation						x	x
Oedema peripheral						x	x
Malnutrition			x
Abdominal pain upper							x
Carcinoma testes						x
Post procedural haemorrhage						x	x
Respiratory failure						x	x

Information about indications was extracted from the indications and usage sections of the labels.

Indication			Labels
Phenylketonuria			x			x	x

Side effects:	14
Source:	EMA

Side effects:	20
Source:	medicines.org.au

Side effects:	20
Source:	Medsafe

Side effects:	32
Source:	FDA

Side effects:	33
Source:	FDA Structured Product Label

standard – alternative

Tetrahydrobiopterin