Tolvaptan

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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Side effect Data for drug Placebo Labels
1
Thirst def 15.7% 5% x
Polydipsia def 15.7% 5% x
Dry mouth def 12.6% 4.09% x
Nocturia def 11.2% 3.18% x
Polyuria def 11.2% 3.18% x
Pollakiuria def 11.2% 3.18% x
Micturition urgency def 11.2% 3.18% x
Urine output increased 11.2% 3.18% x
Urine output 11.2% 3.18% x
Asthenia def 8.52% 4.09% x
Constipation def 7.17% 1.82% x
Diabetes mellitus def 6.28% 0.909% x
Hyperglycaemia def 6.28% 0.909% x
Body temperature increased def 4.04% 0.909% x
Anorexia def 3.59% 0.909% x
Decreased appetite 3.59% 0.909% x
Breast disorder def x
Colitis def x
Connective tissue disorder def x
Diabetic ketoacidosis def x
Disseminated intravascular coagulation def x
Embolism def x
Gastrointestinal disorder def x
Cardiac disorder def x
Haemorrhage def x
Mediastinal disorder def x
Nausea def x
Pulmonary embolism def x
Rhabdomyolysis def x
Cerebrovascular accident def x
Thrombosis def x
Urinary tract disorder def x
Angiopathy def x
Venous thrombosis def x
Ventricular fibrillation def x
Deep vein thrombosis def x
Prothrombin level increased x
Colitis ischaemic def x
Ketoacidosis x
Cardiac fibrillation x
Urethral haemorrhage def x
Clot blood def x
Dissecting aortic aneurysm, thoracic x
Hyponatraemic x
Intracardiac thrombus x
Respiratory failure def x
Death x
Vaginal haemorrhage def x
Indication Labels
Cardiac failure def x
Hepatic cirrhosis def x
Hyponatraemia def x
Inappropriate antidiuretic hormone secretion def x
Neurological symptom x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: C03XA01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. tolvaptan : 48 side effects (FDA XML label)