Colchicine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2
Diarrhoea def 23% - 76.9% 13.6% x x
Gastrointestinal disorder def 25.7% - 76.9% 20.3% x
Nausea def 4.05% - 17.3% 5.08% x x
Vomiting def 0% - 17.3% 0% x x
Fatigue def 1.35% - 3.85% 1.69% x
Mediastinal disorder def 1.92% - 2.7% 0% x
Dissecting aortic aneurysm, thoracic 1.92% - 2.7% 0% x
Pharyngolaryngeal pain def 1.92% - 2.7% 0% x
Headache def 1.35% - 1.92% 3.39% x
Nervous system disorder def 1.92% 3.39% x
Disseminated intravascular coagulation def postmarketing x
Myelosuppression def postmarketing x
Abdominal discomfort 0% 3.39% x
Discomfort def 0% 3.39% x
Abdominal cramps def x
Abdominal pain def x x
Agranulocytosis def x x
Alopecia def x x
Anaemia def x x
Aplastic anaemia def x x
Azoospermia def x
Rash def x x
Gastrointestinal haemorrhage def x
Haemorrhage def x
Lactose intolerance def x
Leukopenia def x
Cramp muscle def x
Myopathy def x x
Myotonia def x
Oligospermia def x
Pancytopenia def x
Neuropathy peripheral def x
Purpura def x
Rhabdomyolysis def x
Thrombocytopenia def x x
Hepatic function abnormal x
Creatine phosphokinase increased def x
Hepatocellular injury x
Muscular weakness def x
Aspartate aminotransferase increased def x
Alanine aminotransferase increased def x
Myalgia def x
Peripheral motor neuropathy def x
Rash maculo-papular def x
Neuropathy def x x
Gout flare x
Weakness def x
Indication Labels
Body temperature increased def x
Brucellosis def x
Familial mediterranean fever def x
Gout def x x
Gout acute x
Pain def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: M04AC01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. COLCHICINE : 17 side effects (FDA XML label)
  2. Colchicine : 42 side effects (FDA XML label)