Search results :

Irinotecan

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01XX19

Side effects

Options: Show MedDRA Preferred Terms,   display only 20 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Alopecia 16.8% - 72% x x x x x x x x x x x x x x x x x x x x x x x x
Diarrhoea postmarketing, 1.6% - 88% x x x x x x x x x x x x x x x x x x x x x
Leukopenia 0% - 98.6% x x x x x x x x x x x x x x x x x x x x x x x
Nausea 2.1% - 86.2% x x x x x x x x x x x x x x x x x x x x x x x x
Pain 2% - 61.5% x x x x x x x x x x x x x x x x x x x x x x x x
Abdominal cramps 8.7% - 57% x x x x x x x x x x x x x x x x x x x x x x x
Sweating 0% - 57% x x x x x x x x x x x x x x x x x x x x x x x
Visual disturbance 15% x
Asthenia 4.2% - 76% x x x x x x x x x x x x x x x x x x x x x x x
Abdominal pain 0.7% - 67.7% x x x x x x x x x x x x x x x x x x x x x x x x
Rash 0% - 46.1% x x x x x x x x x x x x x x x x x x x x x x x
Vomiting postmarketing, 2.8% - 67% x x x x x x x x x x x x x x x x x x x x x x x x
Flatulence 0% - 12.2% x x x x x x x x x x x x x x x x x x x x x x x
Lacrimation 12% x x x x x x x x x x x x x x x x x x
Salivation 11% x
Dyspepsia 0% - 10.5% x x x x x x x x x x x x x x x x x x x x x x x
Miosis 10% x x x x x x x x x x x x x x x x x x
Insomnia 0% - 19% x x x x x x x x x x x x x x x x x x x x x x x
Headache 0.7% - 17% x x x x x x x x x x x x x x x x x x x x x x x
Body temperature increased 0.4% - 45.4% x x x x x x x x x x x x x x x x x x x x x x x x
Back pain 1.6% - 14.5% x x x x x x x x x x x x x x x x x x x x x x x
Constipation 0.4% - 32.3% x x x x x x x x x x x x x x x x x x x x x x x x
Rhinitis 0% - 16% x x x x x x x x x x x x x x x x x x x x x x x
Anaemia 2.1% - 98.6% x x x x x x x x x x x x x x x x x x x x x x x x
Chills 0% - 14% x x x x x x x x x x x x x x x x x x x x x x x
Stomatitis 0.7% - 12% x x x x x x x x x x x x x x x x x x x x x x x
Anorexia 0.7% - 55% x x x x x x x x x x x x x x x x x x x x x x x x
Febrile neutropenia 0.7% - 14.6% x x x x x x x x x x x x x x x x x x x x x x x
Oedema 1% - 10% x x x x x x x x x x x x x x x x x x x x x x x
Flushing 0% - 11% x x x x x x x x x x x x x x x x x x x x x x x
Vasodilation 0% - 11% x x x x x x x x x x x x x x x x x x x x x x
Enlargement abdomen 0% - 10% x x x x x x x x x x x x x x x x x x x x x x x
Bradycardia 5% x x x x x x x x x x x x x x x x x
Dehydration postmarketing, 4% - 15% x x x x x x x x x x x x
Dyspnoea postmarketing, 0% - 22% x x x x x x x x x x x
Neutropenia 0% - 98.6% x x x x x x x x x x x x x x x x x x x
Piloerection 3% x
Mucosal inflammation 1% - 76.3% x x x x x x x x x x x x x x x x x x x x x x x
Thrombocytopenia 0% - 98.6% x x x x x x x x x x x x x x x x x x x x x x x x
Confusional state 0% - 4.1% x x x x x x x x x x x x x x
Dizziness 0% - 21.1% x x x x x x x x x x x x x x x x x x x x x x x
Neutropenic infection 0% - 2.2% x x x x x x x x x x x x x x x x x x x x x x
Somnolence 1.3% - 9.4% x x x x x x x x x x x x x x x x x
Pneumonia 1% - 3.6% x x x x x x x x x x x x x x
Cough 0% - 20.2% x x x x x x x x x x x x x x x x x x x x x x x
Haemorrhage postmarketing, 1% - 5% x x x x x x x x x x x x x x x x x x x x x x x
Hypotension postmarketing, 0% - 11.4% x x x x x x x x x x x x x x x x x x x
Dermatitis exfoliative 0% - 26.5% x x x x x x x x x x x x x x
Colitis postmarketing x x x x x x x x x
Colitis ulcerative postmarketing x x
Infection postmarketing, 0% - 33.6% x x x x x x x x x x x x x x x x x x x x x x x x
Connective tissue disorder postmarketing x x
Dysarthria postmarketing x x x x x x x x x x x
Gastrointestinal disorder postmarketing x x
Gastrointestinal haemorrhage postmarketing x x x x x x x x x x x x x
Cardiac disorder postmarketing x
Hiccups postmarketing x x x x x x x
Hypersensitivity postmarketing x x x x x x x x x x x x x x x x
Hyponatraemia postmarketing x x x x x x x x x x x x x x x x x
Immune system disorder postmarketing x x
Intestinal obstruction postmarketing x x
Intestinal perforation postmarketing x x x x x x x x x x
Renal failure acute postmarketing x x x x x x x x x x x x
Lung disorder postmarketing x x x x x x x x x x x x x x x x
Mediastinal disorder postmarketing x x
Megacolon postmarketing x x x x x x
Megacolon toxic postmarketing x x x x
Cramp muscle postmarketing x x x x x x x x x x x
Nervous system disorder postmarketing x x
Pancreatitis postmarketing x x x x x x x x x x x x x x x x x x
Paraesthesia postmarketing x x x x x x x x x
Shock postmarketing x x x x x x x x x x
Speech disorder postmarketing x x
Ulcer postmarketing x x x x x x x x x x x x x x x
Colitis ischaemic postmarketing x x x x x x x x
Lung infiltration postmarketing x x x x x x x x x x
Sepsis postmarketing x x x x x x x x x x x x x x x x x x x
Caecitis postmarketing x x x x x x x x x x
Cholinergic syndrome postmarketing, 0% - 1.4% x x x x x x x x x x x x x x x x x x x x x x x x
Anaphylactoid reaction postmarketing x x x x x x x x x x x x x x x
Neutropenic enterocolitis postmarketing x x
Metastases to liver postmarketing x x x x x x x x x x x x x x x
Hypovolaemia postmarketing x x
Lipase increased postmarketing x x x x x x x x
Thromboembolic event postmarketing, 5.4% - 11.4% x x x x x x x x x x x x x x x x x x x x x
Ileus postmarketing x x x x x x x x x x x x x x x
Renal impairment postmarketing x x x x x x x x x x x x x x
Angina pectoris x x x x x x x x x x
Arrhythmia x x x x x x x x x x x x x
Neoplasm malignant x
Colon cancer x x x x x x x x x x x
Cerebral infarction x x x x x x x x x x
Sudden death x x x x x x x x x x
Extravasation x
Fatigue x
Cardiac arrest x x x x x x x x x x
Hepatomegaly x x x x x x x x x x x x
Hyperbilirubinaemia x x
Hypertension x
Hypokalaemia x x
Orthostatic hypotension x x x x x x x x x x x x x x x x
Ischaemia x x x x x x x x x x x x
Jaundice x x x x x x x x x x x x x x
Lung neoplasm x x x x x x x x x x x x x x x x
Lymphopenia x x x x x x x x x x x x x x x x x x x x x x
Myocardial infarction x x x x x x x x x x
Neoplasm x x x x x x x x x x x x x
Genetic polymorphism x
Pulmonary embolism x x x x x x x x x x x
Rectal disorder x x
Salivary hypersecretion x x x x x x x x x x x x x x x x x
Cerebrovascular accident x x x x x x x x x x
Syncope x x x x x x x x x x x x x x
Thrombophlebitis x x x x x x x x x x x
Thrombosis x x x x x x x x x x
Tumour lysis syndrome x x
Upper respiratory tract infection x x x x x x x x x x x x
Angiopathy x x x x x x x x x x
Vertigo x x x x x x x x x x x x
Weight decreased x x x x x x x x x x x x x x x x x x x x
Peripheral vascular disorder x x x x x x x x x x
Acute leukaemia x
Hypokinesia x
Embolus leg x x x x x x x x x x
Hypomagnesaemia x x
Accidental injury x x x x x x x x x x x x
Myocardial ischaemia x x x x x x x x x x
Phosphatase alkaline increased x x x
Aspartate aminotransferase increased x x x
Arterial thrombosis x x x x x x x x x x
Lung cancer metastatic x x x x x x x x x x x x x x x x
Sickness x x x
Malaise x x
Frequent bowel movements x
Blood bilirubin increased x x
Blacked-out (not amnesia) x x
Electrolyte imbalance x
Akathisia x x x x x x x
Cough increased x x
Gait disturbance x x
Serum creatinine increased x x
Sweating increased x x x x x x x x x x x x x x x x x x
Hypotension orthostatic symptomatic x
Hand and foot syndrome secondary to sickle cell anaemia 0% - 20.3% x x x x x x x x
Hand rash x
Neutropenic sepsis x x x x x x x x x x x x x x x x x x x x x x
Bilirubin abnormal x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Irinotecan

Side effects:51
Source:BC Cancer

IRINOTECAN

Side effects:31
Source:FDA Structured Product Label

IRINOTECAN

Side effects:56
Source:FDA Structured Product Label

IRINOTECAN

Side effects:49
Source:FDA Structured Product Label

IRINOTECAN

Side effects:49
Source:FDA Structured Product Label

IRINOTECAN

Side effects:56
Source:FDA Structured Product Label

IRINOTECAN

Side effects:56
Source:FDA Structured Product Label

IRINOTECAN

Side effects:81
Source:FDA Structured Product Label

IRINOTECAN HYDROCHLORIDE / CAMPTOSAR

Side effects:61
Source:FDA

IRINOTECAN

Side effects:73
Source:FDA Structured Product Label

Irinotecan

Side effects:76
Source:FDA Structured Product Label

irinotecan

Side effects:77
Source:FDA Structured Product Label

IRINOTECAN

Side effects:80
Source:FDA Structured Product Label

Irinotecan

Side effects:86
Source:FDA Structured Product Label

IRINOTECAN HYDROCHLORIDE / CAMPTOSAR

Side effects:77
Source:FDA

irinotecan HCI injection / Camptosar

Side effects:87
Source:FDA

IRINOTECAN HYDROCHLORIDE / CAMPTOSAR

Side effects:88
Source:FDA

IRINOTECAN HYDROCHLORIDE / CAMPTOSAR

Side effects:89
Source:FDA

IRINOTECAN HYDROCHLORIDE / CAMPTOSAR INJECTION

Side effects:96
Source:Health Canada

IRINOTECAN HYDROCHLORIDE / CAMPTOSAR

Side effects:99
Source:FDA

Irinotecan hydrochloride / IRINOTECAN ALPHAPHARM

Side effects:115
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label