Methylnaltrexone bromide

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1
Abdominal distension def x
Abdominal pain def x
Abscess def x
Anaemia def x
Aneurysm def x
Anxiety def x
Aphasia def x
Apnoea def x
Arthralgia def x
Ascites def x
Asthenia def x
Back pain def x
Bacteraemia def x
Mental disorder def x
Breast cancer def x
Breast disorder def x
Bronchitis def x
Bunion def x
Neoplasm malignant def x
Candidiasis def x
Oral candidiasis def x
Cellulitis def x
Neck pain def x
Chest pain def x
Clostridial infection def x
Tongue coated x
Coma def x
Confusional state def x
Connective tissue disorder def x
Convulsion def x
Cough def x
Cyanosis def x
Cyst def x
Decubitus ulcer def x
Dysphagia def x
Dehydration def x
Delirium def x
Delusion def x
Diarrhoea def x
Disseminated intravascular coagulation def x
Dizziness def x
Drooling x
Dysarthria def x
Dyspnoea def x
Ecchymosis def x
Oedema def x
Effusion def x
Embolism def x
Epistaxis def x
Eye disorder def x
Failure to thrive def x
Fatigue def x
Body temperature increased def x
Fibrosis def x
Fistula def x
Flatulence def x
Flushing def x
Pathological fracture def x
Gastrooesophageal reflux disease def x
Gastrointestinal disorder def x
Hallucination def x
Headache def x
Cardiac arrest def x
Cardiac disorder def x
Cardiac failure def x
Cardiac failure congestive def x
Cardiac murmur def x
Haematoma def x
Haematuria def x
Haemorrhage def x
Haemorrhoids def x
Hypercalcaemia def x
Hyperglycaemia def x
Hyperhidrosis def x
Hyperkalaemia def x
Hypoaesthesia def x
Hypocalcaemia def x
Hypoglycaemia def x
Hypokalaemia def x
Hyponatraemia def x
Hypotension def x
Orthostatic hypotension def x
Cerumen impaction x
Infarction def x
Infection def x
Inflammation def x
Ischaemia def x
Renal failure acute def x
Kyphosis def x
Lethargy def x
Lung disorder def x
Chronic obstructive pulmonary disease def x
Mediastinal disorder def x
Myocardial infarction def x
Myoclonus def x
Nasal congestion def x
Nasopharyngitis def x
Nausea def x
Neoplasm def x
Nervous system disorder def x
Nervousness def x
Neutropenia def x
Night sweats def x
Obstruction def x
Osteomyelitis def x
Pain def x
Intractable pain def x
Pancreatitis def x
Piloerection def x
Pleural disorder def x
Pleural effusion def x
Pneumonia def x
Pneumonia aspiration def x
Polyp def x
Pruritus def x
Psoriasis def x
Pulmonary oedema def x
Pulmonary embolism def x
Pulmonary fibrosis def x
Rales x
Proctalgia def x
Renal failure def x
Respiratory tract infection def x
Rhonchi def x
Seizures def x
Shock def x
Septic shock def x
Shoulder pain def x
Salivary hypersecretion def x
Skin infection def x
Skin ulcer def x
Muscle spasms def x
Speech disorder def x
Gastric disorder def x
Gastric ulcer def x
Stomatitis def x
Aphthous stomatitis def x
Cerebrovascular accident def x
Withdrawal syndrome def x
Sweating def x
Tachycardia def x
Tinnitus def x
Tooth impacted def x
Tremor def x
Ulcer def x
Erythema def x
Urinary tract infection def x
Urinary tract disorder def x
Angiopathy def x
Vomiting def x
Weight increased def x
Wheezing def x
Dry mouth def x
Yawning def x
Chills def x
Agitation def x
Oedema peripheral def x
Bleeding time prolonged x
Creatinine increased def x
Generalised oedema x
Oedema genital def x
Myocardial ischaemia def x
Injection site pain x
Drug withdrawal syndrome def x
Lacrimation increased def x
Pseudomonal sepsis x
Abnormal bowel sounds x
Haemoglobin decreased def x
Respiratory arrest x
Aneurysm ruptured def x
Neoplasm progression def x
Paraparesis def x
Myalgia def x
Respiratory rate decreased def x
Breath sounds abnormal x
Gallop rhythm x
Cold sweat x
Abdominal discomfort x
Abdominal pain upper x
Abdominal tenderness x
Retching def x
Borborygmi x
Disorientation x
Discomfort def x
Tenderness def x
Simple partial seizures x
Feeling cool x
Upset stomach x
Lung infiltration x
Heart rate irregular x
Skin turgor decreased x
Respiratory sounds decreased x
Productive cough def x
Oesophageal obstruction def x
Pulmonary congestion x
Hypoxia def x
Furuncle def x
Disease progression def x
Sepsis def x
Wound dehiscence def x
Onychomadesis def x
Rectal haemorrhage def x
Ulcer haemorrhage x
Mucosal inflammation def x
Gastric ulcer haemorrhage x
Renal impairment def x
Platelet count decreased x
Hypoventilation def x
Lacrimation def x
Suicidal ideation def x
Bladder spasm def x
Anal haemorrhage def x
Bradycardia def x
Respiratory distress def x
Lymphadenopathy def x
Blood pressure increased x
Coordination abnormal x
Visual disturbance x
Depressed level of consciousness def x
Monocyte count increased x
Ca++ increased x
Verbal abuse x
Yellow skin x
Balance disorder x
Heart sounds abnormal x
Sensation of heaviness x
Cancer pain def x
Sedation x
Hot flush def x
Aspiration x
Abscess neck x
Dissecting aortic aneurysm, thoracic x
COPD exacerbation x
Bedridden def x
Partial seizures def x
Infestation NOS x
Pain worsened x
Pharyngolaryngeal pain def x
Albumin low x
Potassium low x
Protein total decreased x
Calcium low x
Hypoglycaemic seizure x
Insomnia def x
Acute coronary syndrome def x
Organ failure x
Infusion related reaction def x
Respiratory failure def x
Ileus def x
Rhinorrhoea def x
Death x
Physical abuse x
Somnolence def x
Indication Labels
Constipation def x
Sickness x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: A06AH01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. METHYLNALTREXONE BROMIDE / RELISTOR : 253 side effects (Health Canada)