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Metrodin

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: G03GA04

Side effects

Options: Hide MedDRA Preferred Terms ,   display only 20 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Abdominal pain Abdominal cramps 14% x x x x x
Abdominal pain postmarketing — 0.537% - 23.2% x x x x x x x x x x x x x x x x x x x x x x
Abdominal distension Enlargement abdomen 2.7% - 13.9% x x x x x x x x x x x x
Fullness abdominal 6.67% x x x
Abdominal distension postmarketing — 1.07% - 1.19% x x x x x x x
Abdominal bloating x x x
Headache Headache postmarketing — 1.05% - 26.5% x x x x x x x x x x x x x x x x x x x x x x
Injection site haemorrhage Injection site bruising 9.7% x x x x x x x
Injection site haemorrhage x x
Injection site bruising Injection site bruising 9.7% x x x x x x x
Pelvic discomfort Pelvic discomfort 8.26% x
Muscle spasms Cramp muscle 6.67% x x x
Muscle spasms postmarketing, 2.67% x x
Cramps of lower extremities x
Breast pain Breast pain female 4.2% - 6.1% x x x x x x x
Breast pain x x x
Upper respiratory tract infection Upper respiratory tract infection 1.7% - 11.9% x x x x
Ovarian hyperstimulation syndrome Ovarian hyperstimulation 3.5% - 7.23% x x x x x x x x x
Ovarian hyperstimulation syndrome very rare — 3.65% - 11.4% x x x x x x x x x x x x x x x
Cyst Cyst 2.86% - 8.11% x x
Pharyngitis Pharyngitis 2.5% - 7.23% x x x x x x x
Sinusitis Sinusitis 2% - 6.02% x x x x x x x x x x x
Breast disorder Breast disorder postmarketing, common x x x x x x
Nervous system disorder Nervous system disorder postmarketing, common x x x x x x x
Varicocele Varicocele common x x x x x
Rhinitis Rhinitis 0.8% - 7.23% x x x x x x x x x
Pelvic pain Pelvic pain female 1.7% - 7.1% x x
Pelvic pain postmarketing, 1.24% - 6.67% x x x x x x x
Dysmenorrhoea Dysmenorrhoea 2.5% - 6.1% x x x
Injection site reaction Injection site reaction postmarketing — 4% - 6.67% x x x x x x x x x x x x x x x x x x x x x
Abortion spontaneous Abortion spontaneous 0.679% - 11.3% x x x x x x x x x x x x x x x x x x x
Foetal disorder Foetal disorder 4.2% x
Gynaecomastia Gynaecomastia common, 3.33% x x x x x x x x x
Metrorrhagia Metrorrhagia postmarketing, 3.6% - 9.3% x x x x x x x x x x
Back pain Back pain 1.8% - 5.1% x x x x x x x x x x
Low back pain x
Diarrhoea Diarrhoea postmarketing — 0% - 7.6% x x x x x x x x x x x x x x x x x x
Loose stools x
Flatulence Flatulence 0% - 8.8% x x x x x x x x x
Abdominal bloating x x x
Nausea Nausea postmarketing — 0% - 13.6% x x x x x x x x x x x x x x x x x x x x x x
Ovarian cyst Ovarian cyst very common, 2.86% - 28.9% x x x x x x x x x x x x x x x x x x
Toothache Toothache 3.61% x x x x x
Migraine Migraine 3.61% x x x x x x x
Acne Acne common, 0% - 6.67% x x x x x x x x x x x x x x x
Influenza like illness Influenza-like symptoms 2.6% - 4.2% x x x x x x
Dermoid cyst Dermoid cyst 3.33% x x x x
Injection site inflammation Injection site inflammation 2.41% - 4.22% x x x x x x x x
Gastrointestinal pain Abdominal pain postmarketing — 0.537% - 23.2% x x x x x x x x x x x x x x x x x x x x x x
Pain Pain postmarketing, 0% - 8.11% x x x x x x x x x x x x x x x x x
Ache x x x
Abdominal discomfort Abdominal discomfort postmarketing — 1.5% - 2.9% x x x x x x x x x
Upset stomach x
Weight increased Weight increased common, 0% - 3.6% x x x x x x x
Ovarian disorder Ovarian disorder 1.7% - 8.11% x x x x x x
Urinary tract infection Urinary tract infection postmarketing, 0% - 4.4% x x x x x x
Dermatitis Rash postmarketing, 2.67% - 3.33% x x x x x x x x x x x x
Rash Rash postmarketing, 2.67% - 3.33% x x x x x x x x x x x x
Vaginal discharge Vaginal discharge postmarketing, 2.67% x x x x
Leukorrhea 1.7% - 3.4% x x
Vaginal haemorrhage Spotting vaginal 2.67% x x x
Vaginal haemorrhage postmarketing, 0% - 8.57% x x x x x x x x x x x x x x x x
Vomiting Vomiting postmarketing — 0% - 2.7% x x x x x x x x x x
Hyperemesis x
Mood swings Mood swings 0% - 5.1% x x x x x
Affect lability Mood swings 0% - 5.1% x x x x x
Application site oedema Application site oedema 2.53% x x x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue postmarketing, common x x x x x x x
Skin disorder x
Cough Cough 1.7% - 2.6% x x x x x x x x
Cough increased x
Cystitis Cystitis 2.41% x x x x x x x
Bladder pain Cystitis 2.41% x x x x x x x
Cystitis noninfective Cystitis 2.41% x x x x x x x
Dizziness Dizziness 0% - 2.5% x x x x x x x x x x x
Syncope x
Dyspepsia Dyspepsia 1.7% - 3.5% x x x x x x x
Body temperature increased Body temperature increased 0% - 4.2% x x x x x x x x x x x x x x x x
Reaction febrile x x x
Mouth ulceration Ulcerative stomatitis 2.41% x x x x x
Pollakiuria Pollakiuria 2.41% x x x x x x
Uterine haemorrhage Uterine haemorrhage 2.41% x x x x
Viral infection Viral infection 2.41% x x x x x x x x
Malaise Malaise 2.41% x x x x x x x x x x
Discomfort Malaise 2.41% x x x x x x x x x x
Discomfort x
Feeling abnormal Malaise 2.41% x x x x x x x x x x
Ill-defined disorder Malaise 2.41% x x x x x x x x x x
Menopausal symptoms Hot flush postmarketing, 0% - 5.71% x x x x x x x x x
Hot flush Hot flush postmarketing, 0% - 5.71% x x x x x x x x x
Genital pain Gynecological-related pain 2.41% x x x x x
Asthenia Fatigue 2.26% x x x
Fatigue Fatigue 2.26% x x x
Injection site pain Injection site pain 0.5% - 6.67% x x x x x x x x x x x x x x
Constipation Constipation postmarketing, 0% - 2.7% x x x x x x x x x x x x x
Abdominal pain lower Abdominal pain lower 1.49% - 2.86% x x
Ectopic pregnancy Ectopic pregnancy 0.198% - 3.8% x x x x x x x x x x x x x x x x x x
Fungal infection Fungal infection 2% x x x
Menstrual disorder Menstrual disorder 0.9% - 2.5% x x
Cervix disorder Uterine cervical lesion 0.9% - 2.5% x x
Cervix disorder 0% - 2.86% x x x
Genital candidiasis Genital candidiasis 0.9% - 2.5% x x
Neck pain Neck pain 0% - 2.7% x x x
Dehydration Dehydration 0% - 2.7% x x x
Depression Depression 0% - 2.7% x x x
Dermatitis exfoliative Dermatitis exfoliative 0% - 2.7% x x x
Hypertension Hypertension 0% - 2.7% x x x
Injury Accidental injury 0% - 2.7% x x x
Breast tenderness Breast tenderness postmarketing, 2% x x x x x x x x x x x
Infection Infection postmarketing x x x
Connective tissue disorder Connective tissue disorder postmarketing x x
Contusion Contusion postmarketing x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing x x x x x x x
Gastrointestinal symptom NOS x x
Hypersensitivity Hypersensitivity very rare, postmarketing x x x x x x x x x x x x x x x
Nasopharyngitis Nasopharyngitis postmarketing x x
Multiple pregnancy Multiple pregnancy postmarketing x
Pruritus Pruritus postmarketing x x x x x x x
Swelling Swelling postmarketing x x x x x x x x x x
Angiopathy Angiopathy postmarketing x x x x x
Erythema Redness postmarketing x x x x x x x x
Erythema x x x x x x x x
Anaphylactic shock Anaphylactoid reaction postmarketing x x x x x x x
Anaphylactic shock very rare x x x x
Anaphylactoid reaction Anaphylactoid reaction postmarketing x x x x x x x
Ovarian enlargement Ovarian enlargement postmarketing x x x x x x x x x x x x x x x x x x x x
Infestation Infestation NOS postmarketing x x
Asthma Asthma very rare, postmarketing x x x x x x x
Exacerbation of asthma x
Embolism Thromboembolism very rare, postmarketing x x x x x x x x
Thromboembolic event x x x x
Embolism venous Thromboembolism very rare, postmarketing x x x x x x x x
Immune system disorder Immune system disorder very rare x x
Mediastinal disorder Mediastinal disorder very rare x x x
Shock Shock very rare x x
Syncope x
Congenital anomaly Congenital anomaly x x x x x x x x x x x x x x
Developmental delay Congenital anomaly x x x x x x x x x x x x x x
Multiple congenital abnormalities Multiple congenital abnormalities x x
Abscess Abscess x
Alopecia Alopecia x x x x
Decreased appetite Anorexia x x
Anxiety Anxiety x x x
Arthralgia Arthralgia x x x
Musculoskeletal discomfort Arthralgia x x x
Myalgia x x
Atelectasis Atelectasis x x x
Pneumothorax Atelectasis x x x
Mental disorder Mental disorder x
Coagulopathy Coagulopathy x
Bronchitis Bronchitis x x
Congestive cardiomyopathy Congestive cardiomyopathy x x
Chest pain Chest pain x x x
Conjunctivitis Conjunctivitis x
Cryptorchism Cryptorchism x x
Drug abuse Drug abuse x x x
Dyspnoea Dyspnoea x x x x x x
Dysuria Dysuria x
Eczema Eczema x
Oedema Oedema x x
Endocrine disorder Endocrine disorder x
Congenital eye disorder Congenital eye disorder x
Eye disorder Congenital eye disorder x
Assisted fertilisation Fertilization x x x x x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease x
Haematoma Haematoma x x x
Peritoneal haemorrhage Peritoneal haemorrhage x x x x x x x x x x x x x x
Haemoptysis Haemoptysis x x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Haemorrhoids Haemorrhoids x x
Genital herpes Genital herpes x
Herpes simplex Herpes simplex x
Herpes zoster Herpes zoster x x
Joint dislocation Hip dislocation x x
Benign hydatidiform mole Hydatidiform mole x
Hydrocephalus Hydrocephalus x x
Hypotension Hypotension x x
Influenza Influenza x x
Arthropathy Arthropathy x
Osteoarthritis Arthropathy x
Nephrolithiasis Calculus of kidney x
Premature labour Premature labour x x x x x x x x x x x
Leukopenia Leukopenia x
Systemic lupus erythematosus Systemic lupus erythematosus x x
Melaena Melaena x
Menorrhagia Menorrhagia x
Nasal congestion Nasal congestion x
Neoplasm Neoplasm x x x x x x x x x x x
Nervousness Nervousness x x x
Tension Nervousness x x x
Neutropenia Neutropenia x
Otitis media Otitis media x
Palpitations Palpitations x x
Paraesthesia Paraesthesia x x
Pilonidal cyst Pilonidal cyst x x x x
Pregnancy Pregnancy x x x x x
Pruritus genital Pruritus genital x x
Acute respiratory distress syndrome Acute respiratory distress syndrome x
Spermatocele Spermatocele x x
Hyperhidrosis Sweating x
Syncope Syncope x
Syncope vasovagal x
Loss of consciousness Syncope x
Tachycardia Tachycardia x x x x
Thirst Thirst x x
Thrombosis Thrombosis x
Tooth disorder Tooth disorder x x x
Urinary incontinence Urinary incontinence x
Urticaria Urticaria x x x x x x x
Uterine disorder Uterine disorder x
Vulvovaginal pruritus Vaginal itching x
Vaginal inflammation Vaginal inflammation x x
Vaginal infection Vaginal inflammation x x
Varicose vein Varicose vein x x
Presyncope Syncope vasovagal x
Vulvovaginitis Vulvovaginitis x
Chills Chills x x x
Adnexal torsion Torsion of ovary x x x x x x
Adnexal torsion x x x x x x x x x x x x x x
Blood urea increased Blood urea increased x
Swelling face Swelling face x x
Complication of pregnancy Pregnancy disorder x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Dry skin Dry skin x x x x
Uterine enlargement Uterine enlargement x x x
Uterine spasm Uterine spasm x
Trisomy 18 Trisomy 18 x x
General symptom General symptom x
Abnormal faeces Abnormal faeces x
Upper limb fracture Upper limb fracture x
Emotional distress Distress x x
Myalgia Myalgia x x
Tachypnoea Tachypnoea x x x
Abdominal pain upper Abdominal pain upper x
Tenderness Tenderness x
Hyperaesthesia Nipple pain x
Nipple pain Nipple pain x
Oropharyngeal discomfort Throat sore x
Oropharyngeal pain Throat sore x
Sepsis Sepsis x
Secondary hypogonadism Secondary hypogonadism x x
Blood bilirubin increased Blood bilirubin increased x
Induration Induration x
Anovulatory cycle Anovulatory cycle x x
Dependence Dependence x
Adnexa uteri pain Ovarian pain x
Lymphadenopathy Lymphadenopathy x x x
Injection site irritation Injection site irritation x
Injection site induration Injection site induration x
Face oedema Face oedema x
Throat irritation Throat irritation x
Genital infection Genital infection x
Exomphalos Omphalocele x x
Blood lactate dehydrogenase increased Blood lactate dehydrogenase increased x
Local reaction Local reaction x x x x x
Red blood cells semen positive Red blood cells semen positive x
Laryngeal pain Pharyngolaryngeal pain x
Insomnia Insomnia x
Ovarian neoplasm Ovarian neoplasm x x x x x x x x x x x x x x x x
Meningocele Meningocele x x
Puerperal pyrexia Puerperal pyrexia x x x x x x x x x x
Somnolence Somnolence x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

FOLLITROPIN ALFA/BETA / FOLLISTIM AQ

Side effects:33
Source:FDA

Follitropin Beta / Follistim

Side effects:42
Source:FDA

FOLLITROPIN

Side effects:31
Source:FDA Structured Product Label

FOLLITROPIN ALFA/BETA / GONAL-F RFF PEN

Side effects:45
Source:FDA

FOLLITROPIN ALFA/BETA / GONAL-F

Side effects:47
Source:FDA

FOLLITROPIN ALFA/BETA / GONAL-F RFF PEN

Side effects:48
Source:FDA

FOLLITROPIN

Side effects:50
Source:FDA Structured Product Label

FOLLITROPIN

Side effects:50
Source:FDA Structured Product Label

follitropin alfa / Gonal-F

Side effects:77
Source:FDA

FOLLITROPIN

Side effects:79
Source:FDA Structured Product Label

FOLLITROPIN ALPHA / GONAL-F PEN

Side effects:42
Source:Health Canada

FOLLITROPIN ALPHA / GONAL-F

Side effects:45
Source:Health Canada

follitropin alfa / follitropin alfa

Side effects:30
Source:EMA

follitropin alfa / follitropin alfa

Side effects:30
Source:EMA

follitropin beta / follitropin beta

Side effects:39
Source:EMA

follitropin

Side effects:39
Source:FDA Structured Product Label

follitropin

Side effects:41
Source:FDA Structured Product Label

UROFOLLITROPIN / BRAVELLE

Side effects:51
Source:FDA

FOLLITROPIN

Side effects:62
Source:FDA Structured Product Label

UROFOLLITROPIN / BRAVELLE

Side effects:85
Source:Health Canada

FOLLITROPIN BETA / PUREGON

Side effects:109
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label