Definition: abnormally large or dilated colon due to congenital absence of myenteric ganglion cells in a distal segment of the large bowel; resultant loss of motor function in this segment causes massive hypertrophic dilatation of the normal proximal colon; condition appears soon after birth; called also Hirschsprung's disease, aganglionic megacolon and pelvirectal achalasia.
Synonyms (terms occurring on more labels are shown first): congenital megacolon
More information: PubMed search and possibly Wikipedia
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