Type IIb hyperlipoproteinemia
Definition: Type IIb hyperlipoproteinemia is caused by mutation in the receptor-binding domain of APOLIPOPROTEIN B-100 which is a major component of LOW-DENSITY LIPOPROTEINS and VERY-LOW-DENSITY LIPOPROTEINS resulting in reduced clearance of these lipoproteins. It is characterized by both hypercholesterolemia and HYPERTRIGLYCERIDEMIA (combined hyperlipidemia).
Synonyms (terms occurring on more labels are shown first): Type IIb hyperlipoproteinemia, Type IIb hyperlipoproteinaemia
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