Definition: Type IIb hyperlipoproteinemia is caused by mutation in the receptor-binding domain of APOLIPOPROTEIN B-100 which is a major component of LOW-DENSITY LIPOPROTEINS and VERY-LOW-DENSITY LIPOPROTEINS resulting in reduced clearance of these lipoproteins. It is characterized by both hypercholesterolemia and HYPERTRIGLYCERIDEMIA (combined hyperlipidemia).
Synonyms (terms occurring on more labels are shown first): Type IIb hyperlipoproteinemia, Type IIb hyperlipoproteinaemia
More information: PubMed search and possibly Wikipedia
Drugs with this indication