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Afatinib

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2
Dermatitis acneiform very common, 0% - 90% x x
Diarrhoea very common, 0% - 96% x x
Rash very common, 0% - 90% x x
Paronychia very common, 0% - 58% x x
Stomatitis very common, 0% - 71% x x
Decreased appetite very common, 0% - 29% x x
Epistaxis very common, 0% - 17% x x
Pruritus very common, 0% - 21% x x
Dry skin very common, 0% - 31% x x
Dehydration common x
Dysgeusia common x
Dyspepsia common x
Renal failure common x
Muscle spasms common x
Aspartate aminotransferase increased common, 2% - 8% x x
Dry eye common x
Renal impairment common x
Hypokalaemia common, 2% - 11% x x
Vomiting 0% - 23% x x
Alanine aminotransferase increased common, 0% - 11% x x
Cystitis common, 0% - 13% x x
Weight decreased common, 0% - 17% x x
Cheilitis common, 0% - 12% x x
Conjunctivitis common, 0% - 11% x x
Body temperature increased common, 0% - 12% x x
Rhinorrhoea common, 0% - 11% x x
Fatigue 0% - 19% x x
Nausea 0% - 25% x
Keratitis uncommon x x
Interstitial lung disease uncommon x x
Pneumonia 0.43% x
Sepsis 0.43% x
Alopecia 0% - 13% x
Back pain 0% - 14% x
Mental disorder x
Infection x x
Connective tissue disorder x
Constipation 0% - 13% x
Cough 0% - 15% x
Dizziness 0% - 11% x
Dyspnoea x
Eye disorder x x
Gastrointestinal disorder x x
Headache 0% - 14% x
Mediastinal disorder x x
Nasopharyngitis 0% - 14% x
Nervous system disorder x
Skin disorder x
Aphthous stomatitis x
Upper respiratory tract infection 0% - 11% x
Urinary tract infection x
Urinary tract disorder x
Mouth ulceration x
Malnutrition x x
Unspecified disorder of skin and subcutaneous tissue x x
Mucosal ulceration x
Conjunctival irritation x
Disease progression x
Left ventricular dysfunction x
Ventricular dysfunction x
Acne pustular x
Hepatobiliary disease x
Mucosal inflammation x
Nail infection x
Oral mucosa erosion x
Pruritus generalised x
Diastolic dysfunction x
Nail bed infection x
Mucosal erosion x
Chapped skin x
Infestation NOS x x
Blood potassium decreased x
Insomnia 0% - 15% x
Pulmonary toxicity x
Conjunctival hyperaemia x
Nasal inflammation x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

afatinib

Side effects:38
Source:FDA Structured Product Label

afatinib (as afatinib dimaleate) / GIOTRIF

Side effects:67
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label