Insomnia

Definition: A sleep disorder characterized by difficulty in falling asleep and/or remaining asleep.

Synonyms (terms occurring on more labels are shown first): insomnia, sleeplessness

More information: PubMed search and possibly Wikipedia

Proteins predicted to cause Insomnia: HTR1D, HTR1B, DRD5 (13 predictions in total) Show drugs with this side effect as MedDRA Preferred Term

Drugs with this side effect busulfan: 84% tacrolimus: 0% - 68% mycophenolic acid: 37.7% - 52.3% ribavirin: 9% - 41% fluvoxamine maleate: frequent, 1% - 35% clozapine: 2% - 33% risperidone: 4% - 32% leuprolide acetate: 12.7% - 31.4% alprazolam: frequent, 8.9% - 29.4% buprenorphine: 3% - 28.2% sertraline: postmarketing, 1% - 28% pamidronate disodium: rare, 0% - 25.1% cytarabine: 14% - 25% clomipramine: 11% - 25% valcyte: 6% - 20% irinotecan: 0% - 19% atovaquone: 9% - 19% bortezomib: 0% - 18.1% aripiprazole: 2% - 18% methylphenidate hydrochloride: postmarketing, 2.8% - 17% zoledronic acid: 15% - 16% asenapine: 6% - 16% strattera: 7% - 15% decitabine: 14.1% donepezil: 6% - 14% imatinib mesylate: 0% - 14% pramipexole dihydrochloride monohydrate: postmarketing, 4% - 13% exemestane: 12.4% guanfacine: postmarketing, 0% - 12% olanzapine: 12% vigabatrin: postmarketing, 10% - 12% glutamine: 0% - 11.1% goserelin: 1% - 11% meridia: 10.7% lamotrigine: 2% - 10% pindolol: 3% - 10% estrogens, conjugated: 5.7% - 9.8% thalidomide: 0% - 9.38% cubicin: 9.17% valproic acid: postmarketing, 9% topiramate: postmarketing, frequent, 8% - 9% tramadol: postmarketing, 0.926% - 9% acamprosate calcium: 6% - 9% fentanyl: postmarketing, 0% - 8% capecitabine: 7% - 8% pergolide mesylate: frequent, 3.2% - 7.9% clobazam: 2% - 7% lamivudine: 7% letrozole: 7% plerixafor: 0% - 7% nelarabine: 0% - 7% natrecor: 2.2% - 6.1% clonidine: 2% - 6% modafinil: 4% - 6% tiagabine hydrochloride: 5% - 6% zonisamide: 3% - 6% oxcarbazepine: 3% - 6% raloxifene: 5.5% conivaptan hydrochloride: 3.81% - 5.41% carmustine: 5% cyclobenzaprine: postmarketing, frequent galantamine: 5% sodium oxybate: postmarketing, infrequent, frequent levetiracetam: 0% - 5% frovatriptan: frequent paricalcitol: 2% - 5% ipratropium bromide: 0.5% - 4.6% estradiol: postmarketing, 4% cyclosporine: postmarketing, 0% - 4% simvastatin: 4% dofetilide: 4% tapentadol: 2% - 4% tipranavir: 3.7% nizatidine: 2.7% - 3.4% rimantadine: 0.9% - 3.4% albuterol: postmarketing, 1% - 3.1% acebutolol (acebutolol hydrochloride): 3% geodon: postmarketing, 0% - 3% celecoxib: 2.3% - 2.9% ibandronate sodium: 0.8% - 2.6% cevimeline hydrochloride: 2.4% tamsulosin: 1.4% - 2.4% mesalamine: postmarketing, 0% - 2.34% balsalazide: 2.32% doxycycline anhydrous: 2% propafenone hydrochloride: 0% - 2% zelnorm: 1% - 2% ursodiol: 1.9% - 1.94% baclofen: rare, 0% - 1.6% terbutaline: 1.5% fesoterodine: 0.4% - 1.3% doxazosin: 0.3% - 1.2% butorphanol tartrate: infrequent dihydroergotamine: infrequent gabapentin: postmarketing, infrequent tamiflu: 1% rivastigmine: infrequent testosterone: postmarketing, 0% - 1% relpax: infrequent almotriptan: infrequent entecavir: 1% rifabutin: 1% diltiazem: 0.952% allopurinol: postmarketing niacin: postmarketing naproxen: postmarketing anastrozole: postmarketing benazepril: postmarketing bisoprolol fumarate: postmarketing verapamil: postmarketing carisoprodol: postmarketing ciprofloxacin: postmarketing diclofenac: postmarketing dicyclomine: postmarketing etodolac: postmarketing felodipine: postmarketing fenofibrate: postmarketing fexofenadine hydrochloride: postmarketing fluconazole: postmarketing flurbiprofen: postmarketing fluvastatin sodium: postmarketing gemcitabine: postmarketing glimepiride: postmarketing ibuprofen: postmarketing iopromide: postmarketing ketoprofen: postmarketing lansoprazole: postmarketing leflunomide: postmarketing lovastatin: postmarketing mefloquine hydrochloride: postmarketing metoclopramide: postmarketing metoprolol: postmarketing singulair: postmarketing nabumetone: postmarketing naltrexone: postmarketing nifedipine: postmarketing omeprazole: postmarketing pantoprazole: postmarketing procarbazine (procarbazine hydrochloride): postmarketing propofol: postmarketing propranolol: postmarketing ramipril: postmarketing ranitidine: postmarketing stavudine: postmarketing trazodone: postmarketing tretinoin: postmarketing triamcinolone: postmarketing zafirlukast: postmarketing pimozide: postmarketing nabilone: postmarketing etonogestrel: postmarketing acitretin: postmarketing clarithromycin: postmarketing imiquimod: postmarketing voriconazole: postmarketing fulvestrant: postmarketing fondaparinux sodium: postmarketing pregabalin: postmarketing lacosamide: postmarketing rosuvastatin calcium: postmarketing glatiramer acetate: postmarketing refludan: postmarketing trelstar: postmarketing levocarnitine epoprostenol sodium mesna iodine levothyroxine nicotine methamphetamine hydrochloride cladribine doxorubicin hydrochloride phenytoin azacitidine Tacrine Hydrochloride Capsules ziagen amphotericin b acetaminophen spectinomycin acyclovir amantadine theophylline anhydrous amiodarone amitriptyline amlodipine amoxapine amoxicillin anagrelide hydrochloride apomorphine iopidine atenolol atorvastatin calcium azithromycin aztreonam betaxolol bicalutamide brimonidine bromocriptine budesonide bupivacaine cabergoline calcitriol captopril carbamazepine carbinoxamine carteolol carvedilol cefaclor cefprozil ceftibuten baycol cetirizine chloroquine Dexchlorpheniramine Maleate chlorpromazine cilazapril (cilazapril monohydrate) cinoxacin Clemastine clomiphene clonazepam plavix codeine cromolyn cyproheptadine dantrolene dapsone desipramine dexamethasone dextroamphetamine sulfate diazepam diazoxide diflunisal diphenhydramine disopyramide metyrosine docetaxel domperidone (domperidone maleate) trusopt dyphylline efavirenz enalapril sodium ethotoin famotidine felbamate fenoldopam fenoprofen calcium flecainide flumazenil flunisolide fluorouracil formoterol fumarate foscarnet sodium fosfomycin tromethamine fosinopril sodium ganciclovir gliclazide glipizide glycopyrrolate granisetron griseofulvin haloperidol hydrocortisone hydromorphone hyoscyamine nardil imipramine indapamide indomethacin iodixanol isoproterenol itraconazole ketamine ketorolac ketotifen (ketotifen fumarate) linezolid lisinopril maxaquin lorazepam losartan loxapine mefenamic acid meloxicam memantine hydrochloride cantil mephenytoin methadone methocarbamol methoxsalen methscopolamine cation methylprednisolone methysergide metolazone metronidazole midazolam midodrine mifepristone minoxidil morphine moxifloxacin hydrochloride nelfinavir mesylate nicardipine nilutamide nisoldipine norethindrone norfloxacin levonorgestrel nortriptyline levofloxacin oxaliplatin oxaprozin oxycodone oxymetholone pemoline pentazocine Pentostatin pentoxifylline perphenazine phentermine pilocarpine pirbuterol piroxicam podofilox pravastatin sodium prazosin prednisolone prednisone prochlorperazine progesterone promethazine propantheline protriptyline quetiapine (quetiapine fumarate) quinapril rabeprazole sodium ephedrine sirolimus riluzole ritonavir rizatriptan (rizatriptan benzoate) rofecoxib ropinirole salmeterol xinafoate sevoflurane sildenafil sulfadiazine risedronate sodium sotalol hydrochloride sulfisoxazole sulindac tamoxifen citrate gatifloxacin temozolomide terazosin tetrahydrozoline thiothixene timolol tinidazole trandolapril trifluoperazine delavirdine mesylate unoprostone isopropyl valacyclovir valsartan zalcitabine zidovudine zolmitriptan vincristine tetrabenazine methsuximide brompheniramine diethylpropion mephobarbital aminophylline Imagent nandrolone medroxyprogesterone acetate pentosan polysulfate sodium arsenic trioxide amiloride estramustine phosphate sodium megestrol oxtriphylline isosorbide-5-mononitrate desmopressin acetate zinecard fludrocortisone bezafibrate nitazoxanide torsemide buserelin (buserelin acetate) octreotide (octreotide acetate) cefpodoxime treprostinil (treprostinil sodium) milnacipran fosphenytoin sodium rotigotine cidofovir anhydrous meropenem ibutilide invirase emtricitabine eprosartan (eprosartan mesylate) tiludronic acid colestipol urofollitropin fluticasone propionate trovafloxacin bendamustine telmisartan ropivacaine hydrochloride nebivolol enablex rifaximin gemifloxacin mesylate telithromycin bexarotene tracleer levitra tadalafil paliperidone valdecoxib viread mometasone furoate caspofungin (caspofungin acetate) desloratadine olmesartan medoxomil febuxostat sacrosidase posaconazole temsirolimus reyataz palonosetron invanz fosaprepitant dimeglumine lubiprostone varenicline tarceva etravirine ambrisentan prezista sitaxsentan sodium lenalidomide gadoversetamide roflumilast micafungin sodium nilotinib (nilotinib hydrochloride monohydrate) sprycel porfimer sodium sutent sitagliptin (sitagliptin phosphate monohydrate) doxercalciferol tigecycline bimatoprost iloprost silodosin sulfasalazine olsalazine methylnaltrexone bromide deferasirox tekturna gadobutrol rifapentine cefdinir ceftobiprole (ceftobiprole medocaril) cefditoren pivoxil raltegravir calcitonin salmon forteo prialt bivalirudin aprotinin degarelix enfuvirtide synarel histrelin sucralfate

Drugs with this indication bupropion buspirone citalopram flurazepam hydrochloride doxepin estazolam fluoxetine isocarboxazid mirtazapine nefazodone oxybutynin paroxetine pentobarbital phenobarbital secobarbital selegiline temazepam triazolam venlafaxine zaleplon zolpidem eszopiclone oxandrolone duloxetine desvenlafaxine ramelteon