Clozapine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Sort by: related terms – frequency

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Weight Gain def 4% — 56% x x x x x x x x x x x x x x x x
Sialorrhea def 6% — 48% x x x x x x x x x x x x x x x x
Drowsiness 25% — 46% x x x x x x x x x x x x x x x x
Sleeplessness 2% — 33% x x x x x x x x x x x x x x x x
Vertigo def 12% — 27% x x x x x x x x x x x x x x x x
Dizziness def 12% — 27% x x x x x x x x x x x x x x x x
Tachycardia def 25% x x x x x x x x x x x x x x x x
Constipation def 10% — 25% x x x x x x x x x x x x x x x x
Vomiting def 3% — 17% x x x x x x x x x x x x x x x x
Nausea def 1% — 17% x x x x x x x x x x x x x x x x
Dyspepsia def 8%, 14% x x x x x x x x x x
Hypotension def 9% x x x x x x x x x x x x x x x x
Headache def 7% x x x x x x x x x x x x x x x x
Tremor def 6% x x x x x x x x x x x x x x x x
Xerostomia def 6% x x x x x x x x x x x x x x x x
Sweating def 6% x x x x x x x x x x x x x x x x
Syncope def 6% x x x x x x x x x x x x x x x x
Fever def 5% x x x x x x x x x x x x x x x x
Nightmares 4% x x x x x x x x x x x x x x x x
Heartburn def 4% x x x x x x x x x x x x x x x x
Agitation def 4% x x x x x x x x x x x x x x x x
Hypertensive disease def 4% x x x x x x x x x x x x x x x x
Convulsions def 3% x x x x x x x x x x x x x x x x
Neutropenia def 3% x x x x x x x x x x x x x x x x
Leukopenia def 3% x x x x x x x x x x x x x x x x
Confusion def 3% x x x x x x x x x x x x x x x x
Diarrhea def 2% x x x x x x x x x x x x x x x x
Fatigue def 2% x x x x x x x x x x x x x x x x
Exanthema def 2% x x x x x x x x x x x x x x x x
Congenital Heart Defects def 1% x x x x x x x x x x x x x x x x
[D]Urgency of micturition 1% x x x x x x x x x x x x x x x x
Nasal congestion 1% x x x x x x x x x x x x x x x x
Ataxia def 1% x x x x x x x x x x x x x x x x
Muscle Weakness def 1% x x x x x x x x x x x x x x x x
Urinary Retention def 1% x x x x x x x x x x x x x x x
Eosinophilia def 1% x x x x x x x x x x x x x x x x
Urinary Incontinence def 1% x x x x x x x x x x x x x x x x
Shortness of Breath 1% x x x x x x x x x x x x x x x x
Angina Pectoris def 1% x x x x x x x x x x x x x x x x
Spasm def postmarketing, 1% x x x x x x x x x x x x x x x x
Myalgia def 1% x x x x x x x x x x x x x x x x
Sore Throat 1% x x x x x x x x x x x x x x x x
Dyspnea def postmarketing, 1% x x x x x x x x x x x x x x x x
Chest Pain def 1% x x x x x x x x x x x x x x x x
Anorexia def 1% x x x x x x x x x x x x x x x x
Anxiety def 1% x x x x x x x x x x x x x x x x
Paresis def 1% x x x x x x x x x x x x x x x x
Pain def 1% x x x x x x x x x x x x x x x x
Angle Closure Glaucoma def postmarketing x x x x x x x x x x x
[D]Respiratory arrest postmarketing x x x x
Status Epilepticus def postmarketing x x x x x x x x x x x x x x x x
[D]Elevated sedimentation rate postmarketing x x x x x x x x x x x x x x x x
Hypertriglyceridemia def postmarketing x x x x x x x x x x
Cataplexy def postmarketing x x x x x x x x x x x x x x x x
Acute pancreatitis unspecified postmarketing x x x x x x x x x x x x x x x x
Ketoacidosis postmarketing x x x x
Fecal Impaction def postmarketing x x x x x x x x x x x x x x x x
impaired glucose tolerance def postmarketing x x
Priapism def postmarketing x x x x x x x x x x x x x x x x
Mitral Valve Insufficiency def postmarketing x x x x
thrombocytosis def postmarketing x x x x x x x x x x x x x x x x
Electroencephalogram abnormal postmarketing x x x x x x x x x x x x x x x x
Tardive Dyskinesia def postmarketing x x x x
Rhabdomyolysis def postmarketing x x x x x x x x x x x x x x x x
Deep Vein Thrombosis postmarketing x x x x x x x x x x x
Paralytic Ileus postmarketing x x x x x x x x x x x x x x x x
Pericardial effusion def postmarketing x x x x
Myocarditis def postmarketing x x x x
Pericarditis def postmarketing x x x x
Drug abuse def postmarketing x x
comatose def postmarketing x x x x
Hyperuricemia def postmarketing x x x x x x x x x x x x x x x x
hypercholesterolemia def postmarketing x x x x x x x x x
Glaucoma def postmarketing x x x x x x
Delirium def postmarketing x x x x x x x x x x x x x x x x
Ventricular Fibrillation def postmarketing x x x x x x x x x x x x x x x x
Systemic infection def postmarketing x x x x x x x x x x x x x x x x
Pleural effusion disorder def postmarketing x x x x x x x x x x x x x x x x
Pulmonary Embolism def postmarketing x x x x x x x x x x x x x x x x
Nephritis, Interstitial def postmarketing x x x x x x x x x x x x x x x x
Erythema Multiforme def postmarketing x x x x x x x x x x x x x x x x
Stevens-Johnson Syndrome def postmarketing x x x x x x x x x x x x x x
Hyponatremia def postmarketing x x x x x x x x x x x x x x x x
Diabetes Mellitus def postmarketing x x
Hyperglycemia def postmarketing x x x x x x x x x x x x x x x x
Photosensitivity def postmarketing x x x x x x x x x x x x x x x x
Deglutition Disorders def postmarketing x x x x x x x x x x x x x x x x
Vasculitis def postmarketing x x x x x x x x x x x x x x x x
Venous Thrombosis def postmarketing x x x x x x
Body Weight decreased def postmarketing x x x x x x x x x x x x x x x x
Hepatitis def postmarketing x x x x x x x x x x x x x x x x
Icterus def postmarketing x x x x x x x x x x x x x x x x
Thrombocytopenia def postmarketing x x x x x x x x x x x x x x x
Paresthesia def postmarketing x x x x x x x x x x x x x x x x
Psychotic Disorders def postmarketing x x x x x x x x x x x x x x x x
Edema def postmarketing x x x x x x x x x x x x x x x x
Swelling def postmarketing x x x x x x x x x x x x x x x x
Cardiomyopathies def postmarketing x x x x
Heart failure def postmarketing x x x x
Myocardial Infarction def postmarketing x x x x
Hypersensitivity def postmarketing x x x x x x x x x x x x x x x x
Polydipsia x x x x x x x x x x x x x x x x x
hypothermia, natural def x x x x x x x x x x x x x x x x x
Stuttering def x x x x x x x x x x x x x x x x x
Memory Loss x x x x x x x x x x x x x x x x x
Paranoia def x x x x x x x x x x x x x x x x x
Parkinsonian Disorders def x x x x x x x x x x x x x x x x x
Dementia def x x x x x x x x x x x x x x x x x
Menopausal hot flushes def x x x x x x x x x x x x x x x x x
Snuffles x x x x x x x x x x x x x x x x x
Sneezing def x x x x x x x x x x x x x x x x x
Eyelid Diseases def x x x x x x x x x x x x x x x x x
Nystagmus def x x x x x x x x x x x x x x x x x
Dysarthria def x x x x x x x x x x x x x x x x x
Amnesia def x x x x x x x x x x x x x x x x x
Hematemesis def x x x x x x x x x x x x x x x x x
Mastodynia x x x x x x x x x x x x x x x x x
Dysmenorrhea def x x x x x x x x x x x x x x x x x
Rectal hemorrhage def x x x x x x x x x x x x x x x x x
Laryngitis def x x x x x x x x x x x x x x x x x
Gastric ulcer def x x x x x x x x x x x x x x x x x
Numbness x x x x x x x x x x x x x x x x x
Abdomen distended x x x x x x x x x x x x x x x x x
Ventricular Premature Complexes def x x x x x x x x x x x x x x x x x
Bradycardia def x x x x x x x x x x x x x x x x x
Petechiae x x x x x x x x x x x x x x x x x
Irritable Mood def x x x x x x x x x x x x x x x x x
Impotence def x x x x x x x x x x x x x x x x x
Leukocytosis def x x x x x x x x x x x x x x x x x
Wheezing x x x x x x x x x x x x x x x x x
Bronchitis x x x x x x x x x x x x x x x x x
Epistaxis def x x x x x x x x x x x x x x x x x
Phlebitis def x x x x x x x x x x x x x x x x x
Thrombophlebitis def x x x x x x x x x x x x x x x x x
Delusions def x x x x x x x x x x x x x x x x x
Hallucinations def x x x x x x x x x x x x x x x x x
Frequency of micturition def x x x
Eructation def x x x x x x x x x x x x x x x x x
Pneumonia def x x x x x x x x x x x x x x x x x
Arthralgia def x x x x x x x x x x x x x x x x x
Chills def x x x x x x x x x x x x x x x x x
Palpitations def x x x x x x x x x x x x x x x x x
cardiac arrhythmia def x x x x x
Anemia def x x x x x x x x x x x x x x x x x
Gastroenteritis def x x x x x x x x x x x x x x x x x
Coughing def x x x x x x x x x x x x x x x x x
Pruritus def x x x x x x x x x x x x x x x x x
Urticaria def x x x x x x x x x x x x x x x x x
Malaise def x x x x x x x x x x x x x x x x x
Infection def x x x x x x x x x x x x x x x x x
Eczema def x x x x x x x x x x x x x x x x x
Dermatitis def x x x x x x x x x x x x x x x x x
Erythema def x x x x x x x x x x x x x x x x x
Indication Labels
Agranulocytosis def x x x x x x x x x x x x x x x
Premenstrual syndrome def x
Schizoaffective Disorder x x x x x x x x
Schizophrenia def x x x x x x x x x x x x x x x
Seizures def x x x x x x x x x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N05AH02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. CLOZAPINE / CLOZARIL TAB 25MG : 147 side effects (Health Canada)
  2. CLOZAPINE / PMS-CLOZAPINE : 143 side effects (Health Canada)
  3. CLOZAPINE / APO-CLOZAPINE : 143 side effects (Health Canada)
  4. CLOZAPINE / FAZACLO ODT : 132 side effects (FDA CDER)
  5. CLOZAPINE / FAZACLO ODT : 131 side effects (FDA CDER)
  6. CLOZAPINE / FAZACLO ODT : 135 side effects (FDA CDER)
  7. CLOZAPINE / FAZACLO ODT : 135 side effects (FDA CDER)
  8. clozapine : 136 side effects (FDA XML label)
  9. clozapine / Clozaril : 132 side effects (FDA CDER)
  10. CLOZAPINE / CLOZARIL : 133 side effects (FDA CDER)
  11. clozapine / Clozaril : 136 side effects (FDA MedWatch)
  12. clozapine : 136 side effects (FDA XML label)
  13. Clozapine : 135 side effects (FDA XML label)
  14. clozapine : 134 side effects (FDA XML label)
  15. Clozapine : 134 side effects (FDA XML label)