Definition: A hypersensitivity reaction characterized by the sudden appearance of symmetrical cutaneous and mucocutaneous macular or popular lesions which evolve into lesions with bright red borders (target lesions). The lesions usually appear in the hands, feet, extremities, and face. Symptoms include fever, malaise, sore throat, cough, vomiting, diarrhea, arthalgia, and myalgia. Causes include infections (most commonly herpes simplex virus), drugs (e.g., sulfonamides, anticonvulsants, and antibiotics), malignancies, and collagen vascular disorders.
Synonyms (terms occurring on more labels are shown first): erythema multiforme, multiforme erythema
Proteins predicted to cause Erythema multiforme: CYP2C9 (inhibition), PTGS2, CYP2C9 (16 predictions in total) Show drugs with this side effect as MedDRA Preferred Term