Medroxyprogesterone acetate

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 14)
1 2 3 4 5 6 7 8 9 10
Congenital anomaly def postmarketing x
Abortion spontaneous def postmarketing x
Abortion missed def postmarketing x
Abscess def postmarketing x x
Pancreatitis acute def postmarketing x
Amnesia def postmarketing x
Anaphylactic shock def postmarketing x x x x x x x x x x
Anaemia def postmarketing x x x x x
Haemolytic anaemia def postmarketing x
Anencephaly def postmarketing x
Angioedema def postmarketing x x x x x x
Anosmia def postmarketing x
Anovulation def postmarketing x x
Anxiety def postmarketing x x
Arthralgia def postmarketing x x x x x
Asthenia def postmarketing x x x x x
Asthma def postmarketing x x x x x x
Ataxia def postmarketing x
Mental disorder def postmarketing x x
Blister def postmarketing x
Bone disorder def postmarketing x x
Breast disorder def postmarketing x x
Bronchospasm def postmarketing x
Cachexia def postmarketing x
Squamous cell carcinoma def postmarketing x
Cerebral infarction def postmarketing
Transient ischaemic attack def postmarketing x
Cervical dysplasia def postmarketing x
Chest pain def postmarketing x x x x x
Cholangitis def postmarketing x
Cholelithiasis def postmarketing x
Cleft palate def postmarketing x
Confusional state def postmarketing x
Connective tissue disorder def postmarketing x
Convulsion def postmarketing x x x x
Cyst def postmarketing x x x x x
Dysphagia def postmarketing x
Scleroderma def postmarketing x x x x
Trisomy 21 def postmarketing x
Dysarthria def postmarketing x
Dysgeusia def postmarketing x
Dyspnoea def postmarketing x x x x x
Eating disorder def postmarketing x
Oedema def postmarketing x x x x x x x
Embolism def postmarketing x x x x
Epistaxis def postmarketing x
Erythema multiforme def postmarketing x x x x
Erythema nodosum def postmarketing x x x x
Oesophageal atresia def postmarketing x
Oesophageal disorder def postmarketing x
Rash def postmarketing x x x x x x x
Eye disorder def postmarketing x
Facial paralysis def postmarketing x x x x x
Fatigue def postmarketing x x x x x x x x x x
Microsomia def postmarketing x
Body temperature increased def postmarketing x x x x x x x x x
Fibrocystic breast disease def postmarketing x x
Fistula def postmarketing x
Gallbladder disorder def postmarketing x x x x
Gastrointestinal disorder def postmarketing x x
Malformation heart (NOS) def postmarketing x
Cardiac disorder def postmarketing x x
Blood disorder def postmarketing x x x x x
Haemorrhagic disorder def postmarketing x
Hepatitis def postmarketing x
Hepatomegaly def postmarketing x
Hereditary disorder def postmarketing x
Hernia def postmarketing x
Diaphragmatic hernia def postmarketing x
Congenital megacolon def postmarketing x
Hoarseness def postmarketing x x x x x
Hydatidiform mole def postmarketing x
Polyhydramnios def postmarketing x
Hydrocephalus def postmarketing x
Hydrops foetalis def postmarketing x
Hypernatraemia def postmarketing x x x
Hypersensitivity def postmarketing x x x x x x x
Hypertension def postmarketing x
Hyperthyroidism def postmarketing x
Hypertriglyceridaemia def postmarketing x x
Hypertrophy def postmarketing x x
Salivary gland enlargement postmarketing x
Hypoglycaemia def postmarketing x
Hypokalaemia def postmarketing x
Hypopituitarism def postmarketing x
Hypotension def postmarketing x
Orthostatic hypotension def postmarketing x
Hypothyroidism def postmarketing x
Immune system disorder def postmarketing x x
Libido increased def postmarketing x x x x x
Infarction def postmarketing x x
Infection def postmarketing x x x x x
Irritability def postmarketing x x x x x x
Ischaemia def postmarketing x
Jaundice def postmarketing x x x x x x x x x
Jaundice cholestatic def postmarketing x x x x x
Renal neoplasm def postmarketing x
Laryngeal oedema def postmarketing x
Laryngospasm def postmarketing x
Leukaemia def postmarketing x
Leukocytosis def postmarketing x
Breast mass def postmarketing x x x x x
Lymphatic disorder def postmarketing x
Mediastinal disorder def postmarketing x
Megacolon def postmarketing x
Malignant melanoma def postmarketing x
Chloasma postmarketing x x x x x x x x
Meningioma def postmarketing x
Premature menopause def postmarketing x
Menorrhagia def postmarketing x x x
Microcephaly def postmarketing x
Myocardial infarction def postmarketing x x
Myoclonus def postmarketing x
Necrosis def postmarketing x
Neoplasm def postmarketing x x x
Nephritis def postmarketing x
Nephritis interstitial def postmarketing x
Nephrotic syndrome def postmarketing x
Nervous system disorder def postmarketing x x
Nervousness def postmarketing x x x x x x x x x
Neuritis def postmarketing x x x x x x
Neurofibroma def postmarketing x
Melanocytic naevus def postmarketing x
IIIrd nerve paralysis def postmarketing x
Oligomenorrhoea def postmarketing x x
Optic neuritis def postmarketing x x x x x x
Osteonecrosis def postmarketing x
Osteoporosis def postmarketing x x x x x
Ovarian cyst def postmarketing x
Palpitations def postmarketing x x x
Pancreatitis def postmarketing x x
Papilloedema def postmarketing x
Paraesthesia def postmarketing x x x x x
Pericarditis def postmarketing x
Porphyria def postmarketing x x
Ectopic pregnancy def postmarketing x
Ptosis def postmarketing x
Proteinuria def postmarketing x
Pruritus def postmarketing x x x x x x x
Benign intracranial hypertension def postmarketing x
Psychotic disorder def postmarketing x
Pulmonary embolism def postmarketing x x x x x x
Purpura def postmarketing x
Thrombotic thrombocytopenic purpura def postmarketing x
Renal infarct postmarketing x
Respiratory disorder def postmarketing x
Acute respiratory distress syndrome def postmarketing x
Retinal vein occlusion def postmarketing x
Salpingitis def postmarketing x
Seizures def postmarketing x
Skin disorder def postmarketing x
Muscle spasms def postmarketing
Speech disorder def postmarketing x
Splenic infarction def postmarketing x
Cerebrovascular accident def postmarketing x x
Sudden infant death syndrome def postmarketing x
Swelling def postmarketing x x x x x x x
Syncope def postmarketing x x x x x
Tachycardia def postmarketing x x x x x
Supraventricular tachycardia def postmarketing x
Thirst def postmarketing x x x x x
Thrombocytopenia def postmarketing x
Thrombophlebitis def postmarketing x x x x x x x x
Thrombosis def postmarketing x x x x x x x x x
Thyroiditis def postmarketing x
Tinnitus def postmarketing x
Tracheo-oesophageal fistula def postmarketing x
Tremor def postmarketing x
Ulcer def postmarketing x
Attention deficit disorder def postmarketing x
Erythema def postmarketing x x x x x
Urinary tract disorder def postmarketing x
Urticaria def postmarketing x x x x x x x
Uterine leiomyoma def postmarketing x x
Angiopathy def postmarketing x x
Venous thrombosis def postmarketing x x x x x x
Vertigo def postmarketing x x
Weight decreased def postmarketing x
Spina bifida def postmarketing x
Urinary retention def postmarketing x
Chills def postmarketing x x x x x
Body odor def postmarketing x x x x x
Hepatic failure def postmarketing x
Agitation def postmarketing x
Mood swings postmarketing x
Acute leukaemia def postmarketing x
Breast discharge def postmarketing x x
Mouth ulceration def postmarketing x
Deep vein thrombosis def postmarketing x x x x x
Migraine def postmarketing x x x x
Glucose tolerance decreased postmarketing x x x x x x
Growth retardation def postmarketing x
Injection site reaction def postmarketing x x x
Intracranial pressure increased def postmarketing x
Muscular weakness def postmarketing x
Phosphatase alkaline increased postmarketing x
Electrocardiogram QT prolonged def postmarketing x
Alanine aminotransferase increased def postmarketing x
Dry skin def postmarketing x x x x x
Arterial thrombosis postmarketing x
Cerebral venous thrombosis postmarketing x
Joint swelling postmarketing x
Polydactyly def postmarketing x
Optic ischaemic neuropathy def postmarketing x
Vaginal dysplasia postmarketing x
Porphyria acute def postmarketing x
Fibroadenoma of breast def postmarketing x
Fibroadenoma def postmarketing x
Malaise def postmarketing x
Myalgia def postmarketing x
Galactorrhoea postmarketing x x x x x x x x
Congenital diaphragmatic hernia postmarketing x
Skull malformation postmarketing x
Ischaemic neuropathy postmarketing x
Sickle cell anaemia with crisis def postmarketing x
Oestrogen low postmarketing x
Limb deformity postmarketing x
Testosterone low postmarketing x
Vaginal cyst postmarketing x x x x x
Venous occlusion def postmarketing x
Intestinal infarction postmarketing x
Sepsis def postmarketing x
Nerve paralysis postmarketing x
Vulval abscess postmarketing x
Ear malformation postmarketing x
Blighted ovum postmarketing x
Rectal haemorrhage def postmarketing x x x x x
Hepatobiliary disease def postmarketing x
Uterine cyst postmarketing x
Antepartum haemorrhage postmarketing x
Macular oedema def postmarketing x
Acute psychosis postmarketing x
Deformity postmarketing x
Cervix carcinoma def postmarketing x x x x x
Cushingoid postmarketing x
Dysplasia def postmarketing x x x x x
Anaphylactoid reaction postmarketing x x x x x x x x
Benign breast neoplasm def postmarketing x
Nephrolithiasis def postmarketing x
Hyperkinesia def postmarketing x
Bradycardia def postmarketing x
Neuropathy def postmarketing x
Blindness def postmarketing x
Respiratory distress def postmarketing x
Blood pressure increased postmarketing x x x x x
Osteoporotic fracture def postmarketing x x x x x
Paralysis def postmarketing x x x x x
Face oedema def postmarketing x
Dysfunction adrenal postmarketing x
Balance disorder postmarketing x
Mass def postmarketing x x x x x x
Stillbirth def postmarketing x
Prematurity postmarketing x
Dissecting aortic aneurysm, thoracic postmarketing x
Memory loss postmarketing x
Infestation NOS postmarketing x
Oestrogen deficiency postmarketing x
Oral mucosal blistering postmarketing x
Thrombocytopenic purpura def postmarketing x
Glucose low postmarketing x x x x x x
Cerebral ischaemia def postmarketing x
Dysphemia postmarketing x
Ovarian cancer def postmarketing x x
Attention deficit/hyperactivity disorder def postmarketing x
Talipes postmarketing x
Death postmarketing x
Single umbilical artery def postmarketing x
Paranoia def postmarketing x
Breast neoplasm def postmarketing x
Hypospadias def postmarketing x
Embolus def postmarketing x x x x x
Weakness def postmarketing x x
Excessive thirst postmarketing x x x x x
Somnolence def postmarketing x x x x x x x
Cerebral haemorrhage def postmarketing x
Abdominal cramps def x
Abdominal distension def x
Abdominal mass x
Abdominal pain def x x x x
Alopecia def x x x x x x x
Anorexia def x
Back pain def x x x x x x
Breast swelling x x x
Bronchitis def x x
Candidiasis def x x x
Vaginal moniliasis x x x
Uterine cervical erosion def x x x x x
Chorea def x
Constipation def x
Coronary artery thrombosis def x x
Cystitis def x x x
Libido decreased def x x x x x
Depression def x x x x
Diarrhoea def x x
Distention def x
Dizziness def x x x x x x x x x
Drowsiness def x x x
Dysuria def x x x
Ectropion def x
Toxic epidermal necrolysis def x
Epilepsy def x
Fertilization def x x x
Headache def x x x x x x x x x
Heartburn def x
Haemangioma def x
Hirsutism def x x x x x x x
Hyperglycaemia def x x
Hypocalcaemia def x
Influenza def x x
Jaundice neonatal def x
Cramps of lower extremities x x x x
Leg pain x x
Leukorrhea def x x x
Liver disorder def x
Breast pain def x x x x x x
Metrorrhagia def x x x x x x x x
Cramp muscle def x x x x x x
Musculoskeletal pain def x
Nasopharyngitis def x x
Nausea def x x x x x x x x x
Pain in extremity def x x
Pharyngitis def x x
Polyp def x
Pruritus vulvae def x
Respiratory tract infection def x
Sinusitis def x x
Sweating def x x x
Thromboembolism def x x x
Upper respiratory tract infection def x
Pollakiuria def x
Urinary tract infection def x x
Vaginal itching x x
Vaginal inflammation def x x x x x x
Varicose vein def x x x x x
Vomiting def x x x x
Weight increased def x x x x
Cerebral thrombosis x
Vaginitis bacterial def x x
Oedema peripheral def x
Hepatic function abnormal x x
Injection site atrophy x
Injection site pain x x x x x
Menstruation irregular def x x x x
Vaginal discharge def x
Increased appetite x
Abdominal discomfort x x x
Abdominal pain lower x
Menometrorrhagia x x
Anorgasmia def x x
Discomfort def x x x x x
Abdominal distress x
Rash hemorrhagic x x x x
Superficial phlebothrombosis x
Vein pain x
Breast tenderness x x x x
Fluid retention x x
Ectropion of cervix x
Eruption x x x x
Atrophy def x
Exacerbation of asthma x
Smear cervix abnormal x
Dementia def x
Rash generalised x x x x x
Abscess sterile x x
Sulphobromophthalein retention x
Carbohydrate tolerance decreased x
Visual disturbance x x
Blood glucose increased x x
Drug interaction def
Sweating increased x x x
Acne def x x x x x x x x x x
Skin haemorrhage
Insomnia def x x x x x x x x x x
Pain during injection x x x
Abdominal bloating def x x x x x x
Mood alteration NOS def x
Vaginal haemorrhage def x
Indication Labels
Amenorrhea secondary x x
Amenorrhoea def x x x x
Becker's muscular dystrophy def x x x x x
Breast feeding def x x x x
Carcinoma def x
Dysmenorrhoea def x
Dyspareunia def x
Endocrine disorder def x
Endometrial hyperplasia def x x
Endometriosis def x x
Flushing def x
Haemorrhage def x x
Hot flush def x
Hyperplasia def x x
Induration def x
Leiomyoma def x x
Lymphangioleiomyomatosis def x x
Menopause def x
Neoplasm malignant def x x x
Nulliparous x x x
Pain def x
Pelvic pain def x
Renal carcinoma def x
Tenderness def x
Unintended pregnancy def x x x
Uterine cancer def x x
Uterine haemorrhage def x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Codes: G03AC06, G03DA02, L02AB02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. MEDROXYPROGESTERONE ACETATE / PROVERA : 18 side effects (Drugs@FDA)
  2. medroxyprogesterone : 43 side effects (FDA XML label)
  3. MEDROXYPROGESTERONE ACETATE / NOVO-MEDRONE - TAB 2.5MG : 59 side effects (Health Canada)
  4. MEDROXYPROGESTERONE ACETATE / GEN-MEDROXY TABLET 5MG : 60 side effects (Health Canada)
  5. MEDROXYPROGESTERONE ACETATE / DEPO-PROVERA : 75 side effects (Drugs@FDA)
  6. MEDROXYPROGESTERONE : 76 side effects (FDA XML label)
  7. medroxyprogesterone : 79 side effects (FDA XML label)
  8. MEDROXYPROGESTERONE ACETATE / DEPO-SUBQ PROVERA 104 : 92 side effects (Drugs@FDA)
  9. MEDROXYPROGESTERONE ACETATE / DEPO-SUBQ PROVERA 104 : 97 side effects (Drugs@FDA)
  10. MEDROXYPROGESTERONE ACETATE / DEPO-PROVERA STERILE AQUEOUS SUSPENSION 150 MG/ML : 311 side effects (Health Canada)