Somnolence

Definition: A disorder characterized by characterized by excessive sleepiness and drowsiness.

Synonyms (terms occurring on more labels are shown first): somnolence

More information: PubMed search and possibly Wikipedia or Medpedia

Proteins predicted to cause Somnolence: CYP2C9, CYP2D6, CYP2D6 (inhibition) (3 predictions in total) Show drugs with this side effect as MedDRA Preferred Term

Drugs with this side effect cyclobenzaprine: 0% - 100% tizanidine: 48% - 92% risperidone: postmarketing, 0% - 67% quetiapine (quetiapine fumarate): 18% - 57% clomipramine: 46% - 54% clonazepam: 1% - 50% trazodone: 3.96% - 46% clozapine: 25% - 46% ropinirole: 7% - 40% guanfacine: postmarketing, 0% - 39% olanzapine: 6% - 39% clonidine: 2% - 38% pramipexole dihydrochloride monohydrate: 6% - 36% apomorphine: 35% carbamazepine: 32% clobazam: 16% - 32% oxcarbazepine: 5% - 31% geodon: 8% - 31% pregabalin: postmarketing, 4% - 28% fluvoxamine maleate: frequent, 1% - 27% progesterone: 27% venlafaxine: 1% - 26.1% valproic acid: postmarketing, 1.7% - 26% paliperidone: 6% - 26% vigabatrin: postmarketing, 17% - 25.6% tramadol: 4.34% - 25% oxycodone: 23% - 24% paroxetine: postmarketing, 1.4% - 24% asenapine: 13% - 24% alprazolam: 6% - 23% levetiracetam: postmarketing, 0% - 23% aripiprazole: 4% - 23% nelarabine: 0% - 23% gabapentin: 4.5% - 21.4% tiagabine hydrochloride: 18% - 21% duloxetine: 7% - 21% baclofen: rare, 5.7% - 20.9% fentanyl: postmarketing, 7% - 20% citalopram: 1% - 18% fluoxetine: postmarketing, 2% - 17% zonisamide: 7% - 17% rufinamide: 11% - 17% granisetron: 4% - 15% sertraline: postmarketing, 0% - 15% topiramate: postmarketing, 10% - 15% tapentadol: 12% - 15% sodium oxybate: postmarketing, 1.08% - 14.3% buprenorphine: 2% - 14% carmustine: 10.8% - 13.6% desvenlafaxine: 4% - 12% strattera: 3% - 11% pergolide mesylate: frequent, 3.7% - 10.1% dicyclomine: 9% letrozole: 2% - 9% zolmitriptan: 4% - 8% lacosamide: 5% - 8% relpax: 3% - 7% pamidronate disodium: rare, 0% - 6% cetirizine: 1.9% - 5.7% terbutaline: 5.5% terazosin: postmarketing, 0.2% - 5.4% doxazosin: 1% - 5% almotriptan: frequent varenicline: frequent sprycel: frequent hydromorphone: postmarketing, 1.6% - 4.7% tamsulosin: 2.99% - 4.3% galantamine: 4% lorazepam: 1.5% - 3.8% bupropion: postmarketing, 2% - 3% dihydroergotamine: 3% memantine hydrochloride: 3% ramelteon: 3% fexofenadine hydrochloride: postmarketing, 0.2% - 2.8% desloratadine: 2.1% azelastine: 1.44% - 2.05% entacapone: 2% nizatidine: 1.6% - 1.9% meridia: 1.7% amlodipine: 0.3% - 1.6% benazepril: 1.56% - 1.6% diltiazem: 1.27% diclofenac: 0.699% - 1% imatinib mesylate: infrequent entecavir: 1% olopatadine: 0.852% naproxen: postmarketing anastrozole: postmarketing azithromycin: postmarketing betahistine hydrochloride: postmarketing bisoprolol fumarate: postmarketing brimonidine: postmarketing verapamil: postmarketing baycol: postmarketing ciprofloxacin: postmarketing cyclosporine: postmarketing etodolac: postmarketing famciclovir: postmarketing felodipine: postmarketing fenofibrate: postmarketing finasteride: postmarketing fluconazole: postmarketing flurbiprofen: postmarketing gemcitabine: postmarketing ibuprofen: postmarketing lidocaine: postmarketing ketoprofen: postmarketing lansoprazole: postmarketing mefloquine hydrochloride: postmarketing meloxicam: postmarketing mesalamine: postmarketing metoprolol: postmarketing singulair: postmarketing morphine: postmarketing nabumetone: postmarketing nalbuphine: postmarketing naltrexone: postmarketing nevirapine: postmarketing omeprazole: postmarketing oxybutynin: postmarketing pantoprazole: postmarketing praziquantel: postmarketing propofol: postmarketing ramipril: postmarketing ranitidine: postmarketing rofecoxib: postmarketing timolol: postmarketing zidovudine: postmarketing medroxyprogesterone acetate: postmarketing pimozide: postmarketing nabilone: postmarketing etonogestrel: postmarketing esmolol hydrochloride: postmarketing perindopril erbumine: postmarketing invirase: postmarketing nebivolol: postmarketing voriconazole: postmarketing glatiramer acetate: postmarketing byetta: postmarketing levocarnitine epoprostenol sodium cycloserine allopurinol estradiol cytarabine mesna iodine niacin nicotine pyridoxine doxorubicin hydrochloride phenytoin Tacrine Hydrochloride Capsules amphotericin b acebutolol (acebutolol hydrochloride) acyclovir albuterol amantadine amifostine anagrelide hydrochloride iopidine atenolol atorvastatin calcium bicalutamide bromocriptine budesonide bupivacaine busulfan butorphanol tartrate cabergoline calcitriol candesartan cilexetil captopril carvedilol cefaclor cefprozil ceftibuten cefuroxime celecoxib cevimeline hydrochloride cilazapril (cilazapril monohydrate) cimetidine codeine deferiprone dronabinol dextroamphetamine sulfate diazepam diazoxide diflunisal dipyridamole donepezil trusopt doxepin efavirenz enalapril sodium estazolam etoposide famotidine felbamate fenoprofen calcium flecainide flumazenil fluorouracil formoterol fumarate foscarnet sodium fosfomycin tromethamine ganciclovir gemfibrozil glipizide hydrochlorothiazide hyoscyamine ifosfamide indapamide crixivan indomethacin iodixanol Iohexol iopromide ioversol ioxilan ipratropium bromide irbesartan irinotecan itraconazole ketoconazole ketorolac labetalol leuprolide acetate levocabastine linezolid lisinopril maxaquin loratadine losartan mefenamic acid methotrexate methylphenidate hydrochloride metoclopramide midodrine minocycline mitotane tablets modafinil moxifloxacin hydrochloride mycophenolic acid nefazodone nelfinavir mesylate nicardipine nifedipine nisoldipine norfloxacin levonorgestrel levofloxacin oxaliplatin oxaprozin pentobarbital Pentostatin phenobarbital pilocarpine piroxicam prazosin promethazine propafenone hydrochloride quinapril rabeprazole sodium sirolimus riluzole rimantadine ritonavir rivastigmine rizatriptan (rizatriptan benzoate) stavudine secobarbital selegiline sevoflurane sildenafil sulindac tacrolimus gatifloxacin temozolomide Thiotepa detrol la trandolapril triazolam trospium delavirdine mesylate ursodiol valsartan zalcitabine zaleplon zolpidem eszopiclone tetrabenazine mephobarbital propoxyphene arsenic trioxide amiloride isosorbide-5-mononitrate desmopressin acetate estrogens, conjugated lithium cation metipranolol Septocaine with epinephrine 1:100 moricizine acitretin nitazoxanide sufentanil buserelin (buserelin acetate) lodoxamide goserelin alfentanil octreotide (octreotide acetate) cefpodoxime clarithromycin milnacipran fosphenytoin sodium rotigotine cidofovir anhydrous meropenem ultiva emtricitabine eprosartan (eprosartan mesylate) tiludronic acid trovafloxacin valcyte tipranavir bendamustine telmisartan zoledronic acid acamprosate calcium ropivacaine hydrochloride enablex gemifloxacin mesylate telithromycin frovatriptan paricalcitol tracleer gadobenic acid levitra tadalafil nitisinone clofarabine valdecoxib viread Carglumic acid azilect febuxostat posaconazole reyataz palonosetron invanz gadodiamide etravirine prezista sitaxsentan sodium lenalidomide gadoversetamide micafungin sodium sitagliptin (sitagliptin phosphate monohydrate) doxercalciferol Tolcapone tigecycline bimatoprost methylnaltrexone bromide rifapentine cefdinir ivermectin ceftobiprole (ceftobiprole medocaril) cefditoren pivoxil gadofosveset calcitonin salmon insulin recombinant human prialt natrecor

Drugs with this indication lamotrigine mirtazapine thalidomide