Linezolid

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Acidosis def postmarketing x x x x x x
Lactic acidosis def postmarketing x x x x x x
Anaphylactic shock def postmarketing x x x x x x
Anaemia def postmarketing x x x x x x x
Angioedema def postmarketing x x
Blister def postmarketing x x
Convulsion def postmarketing x x x x x x x
Leukopenia def postmarketing x x x x x x x
Optic nerve disorder def postmarketing x x x x x
Pancytopenia def postmarketing x x x x x x x
Neuropathy peripheral def postmarketing x x x x x
Skin disorder def postmarketing x x x x x x
Stevens-Johnson syndrome def postmarketing x x
Thrombocytopenia def postmarketing x x x x x x x x
Tooth discolouration def postmarketing x
Tongue discolouration postmarketing x x x x x x x x
Neuropathy def postmarketing x x x x x x x
Blindness def postmarketing x x x x x
Myelosuppression def postmarketing x x x x x x x
Abdominal cramps def x
Abdominal pain def x x x x x x x x
Anorexia def x
Apnoea def x x x x x x
Asthenia def x
Candidiasis def x x x x x x x x
Skin candida def x
Oral candidiasis def x x x x x x x x
Vaginal moniliasis x x x x x x x x
Transient ischaemic attack def x
Colitis def x
Constipation def x x x x x x x x
Cough def x x x x x x
Dermatitis def x
Fungal skin infection def x
Diarrhoea def x x x x x x x x
Dizziness def x x x x x x x x
Dysgeusia def x x x x x x x x
Dyspepsia def x x x x x x x x
Dyspnoea def x x x x x x x
Ecchymosis def x
Oedema def x x x x x x
Eosinophilia def x x x x x x x
Rash def x x x x x x x x
Fatigue def x
Body temperature increased def x x x x x x x
Flatulence def x
Gastritis def x
Gastrointestinal disorder def x
Gastrointestinal haemorrhage def x x x x x x x
Glossitis def x
Headache def x x x x x x x x
Cardiac failure def x
Cardiac failure congestive def x
Haemorrhage def x x x x x x x x
Hyperglycaemia def x
Hypertension def x x x x x x x x
Hypoaesthesia def x
Hypoglycaemia def x
Hypokalaemia def x x x x x x x
Hyponatraemia def x
Jaundice def x
Jaundice cholestatic def x
Cramp muscle def x
Fungal infection def x x x x x x x x
Nausea def x x x x x x x x
Neutropenia def x
Pain def x x x x x x x x
Pancreatitis def x
Paraesthesia def x
Pharyngitis def x x x x x x
Phlebitis def x
Polyuria def x
Pruritus def x x x x x x x x
Rectal disorder def x
Renal failure def x
Respiratory tract infection def x x x x x x
Skin ulcer def x
Stomatitis def x
Thirst def x
Thrombophlebitis def x
Tinnitus def x
Erythema def x
Upper respiratory tract infection def x x x x x x
Urticaria def x
Vaginal inflammation def x
Angiopathy def x
Vertigo def x x x x x x
Vomiting def x x x x x x x x
Dry mouth def x
Peripheral vascular disorder def x
Chills def x
Hepatic function abnormal x x x x x x x x
Amylase increased x
Creatine phosphokinase increased def x
Generalised oedema x x x x x x
Impaired healing x
Injection site reaction def x x x x x x
Lactic dehydrogenase activity increased x
Liver function test abnormal x x x
Mucous membrane disorder x
Biliary colic def x
Aspartate aminotransferase increased def x
Alanine aminotransferase increased def x
Sickness x x x x x x
Decreased appetite x
Disorientation x
Clostridium difficile colitis def x
Creatine phosphokinase serum increased x
Increased thirst x
Sepsis def x x x x x x
Aplasia x
Vision blurred def x
Abdominal pain generalised x x x x x x
Platelet count decreased x x x x x x x x
Vaginal infection def x
Laboratory test abnormal x
Pain localised x x x x x x x
Sweating increased x
Thrombocytosis def x x x x x x
Insomnia def x x x x x x x x
Somnolence def x
Indication Labels
Bacteraemia def x x x x x x x x
Decubitus ulcer def x x x x x x x x
Diabetic foot def x x x x x x x x
Diabetic foot infection x x x x x x
Empiric treatment x
Fasciitis def x
Foot infection x x x x x x
Infection def x x x x x x x x
Necrotising fasciitis def x
Nosocomial pneumonia x x x x x x x x
Osteomyelitis def x x x x x x
Pneumonia def x x x x x x x x
Ulcer def x x x x x x x x
Urinary tract infection def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: J01XX08

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. LINEZOLID / ZYVOX : 25 side effects (Drugs@FDA)
  2. linezolid / Zyvox : 50 side effects (FDA CDER)
  3. LINEZOLID / ZYVOX : 52 side effects (Drugs@FDA)
  4. LINEZOLID / ZYVOX : 55 side effects (Drugs@FDA)
  5. linezolid / Zyvox : 55 side effects (FDA MedWatch)
  6. LINEZOLID / ZYVOX : 58 side effects (Drugs@FDA)
  7. linezolid : 60 side effects (FDA XML label)
  8. LINEZOLID / ZYVOXAM 600 MG : 101 side effects (Health Canada)