Hypertension

Definition: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Synonyms (terms occurring on more labels are shown first): hypertension, arterial hypertension, high blood pressure, hypertension NOS, Vascular Hypertension, systemic hypertension

More information: PubMed search and possibly Wikipedia or Medpedia

Proteins predicted to cause Hypertension: CYP3A4, PTGS2 (inhibition), PTGS1 (inhibition) (7 predictions in total) Show drugs with this side effect as MedDRA Preferred Term

Drugs with this side effect mycophenolic acid: 28.2% - 77.5% tacrolimus: 0% - 56% cyclosporine: postmarketing, rare, 0% - 53% busulfan: 36% Dexmedetomidine: postmarketing, 11% - 28% lantus: 19.6% valcyte: 12% - 18% cytarabine: 4% - 15% zoledronic acid: postmarketing, 5.1% - 12.7% celecoxib: 12.5% amphotericin b: 2.33% - 11.3% leflunomide: postmarketing, 0% - 10% exemestane: 9.8% ibuprofen: postmarketing, 9.68% carmustine: 3.64% - 9.17% Hydroxyprogesterone Caproate: 4.6% - 8.8% conivaptan hydrochloride: 6.35% - 8.11% letrozole: 5% - 8% midodrine: 7.3% ibandronate sodium: 5.3% - 7.3% paricalcitol: 7% ultiva: 1.09% - 6.17% decitabine: 6.06% pamidronate disodium: 0% - 6% goserelin: postmarketing, 6% cubicin: 5.83% nilutamide: 5.3% insulin recombinant human: 3.9% - 5.3% Tacrine Hydrochloride Capsules: frequent citalopram: postmarketing, rare, infrequent, frequent donepezil: frequent fluoxetine: rare, postmarketing, infrequent, frequent gabapentin: infrequent, frequent galantamine: frequent mirtazapine: frequent mitoxantrone: 3.57% - 5% paroxetine: postmarketing, frequent, 0% - 2% pergolide mesylate: rare, frequent, 1.1% - 1.6% ropinirole: postmarketing, infrequent, frequent, 3% - 5% selegiline: postmarketing, frequent tiagabine hydrochloride: frequent venlafaxine: 1.1% - 5% sodium oxybate: frequent aripiprazole: frequent geodon: frequent, 0% - 3% varenicline: frequent sprycel: postmarketing, frequent, 0% - 1% glatiramer acetate: frequent dexamethasone: 0.602% - 4.63% clozapine: 4% ipratropium bromide: 0.9% - 4% memantine hydrochloride: 4% salmeterol xinafoate: postmarketing, 2% - 4% albuterol: postmarketing, 1% - 3.1% olanzapine: 0% - 3% risperidone: postmarketing, infrequent, 3% testosterone: postmarketing, 0% - 3% asenapine: 2% - 3% dolasetron mesylate: 2.19% bupropion: postmarketing, 1% - 2% capsaicin: 1% - 2% fluvoxamine maleate: infrequent, 2% quetiapine (quetiapine fumarate): 1% - 2% ibutilide: 1.19% - 1.2% buspirone: infrequent butorphanol tartrate: postmarketing, infrequent fentanyl: postmarketing, 0% - 1% lamotrigine: infrequent mesalamine: 1% nefazodone: infrequent sertraline: postmarketing, rare, infrequent imatinib mesylate: infrequent topiramate: infrequent zaleplon: infrequent zolpidem: rare, infrequent eszopiclone: infrequent relpax: infrequent baclofen: 0.2% - 0.6% gadobenic acid: 0.5% metaproterenol: 0.4% mesna: postmarketing enoxaparin sodium: postmarketing naproxen: postmarketing anastrozole: postmarketing azelastine: postmarketing bromocriptine: postmarketing budesonide: postmarketing carbamazepine: rare baycol: postmarketing ciprofloxacin: postmarketing clomiphene: postmarketing cyclobenzaprine: postmarketing dextroamphetamine sulfate: postmarketing diclofenac: postmarketing dicyclomine: postmarketing didanosine: postmarketing valproic acid: postmarketing efavirenz: postmarketing etodolac: postmarketing flurbiprofen: postmarketing ganciclovir: postmarketing gemcitabine: postmarketing glycopyrrolate: postmarketing iodixanol: postmarketing iopromide: postmarketing ketoprofen: postmarketing lansoprazole: postmarketing leuprolide acetate: postmarketing lorazepam: postmarketing mefloquine hydrochloride: postmarketing meloxicam: postmarketing metoclopramide: postmarketing nabumetone: postmarketing levonorgestrel: postmarketing oxybutynin: postmarketing procarbazine (procarbazine hydrochloride): postmarketing progesterone: postmarketing propofol: postmarketing ribavirin: postmarketing rofecoxib: postmarketing tramadol: postmarketing valacyclovir: postmarketing vinorelbine: postmarketing medroxyprogesterone acetate: postmarketing carboplatin: postmarketing desflurane: postmarketing octreotide (octreotide acetate): postmarketing voriconazole: postmarketing bortezomib: postmarketing levitra: postmarketing almotriptan: rare pregabalin: rare misoprostol: postmarketing cefdinir: postmarketing venofer: postmarketing aprotinin: postmarketing Corticotropin: postmarketing trelstar: postmarketing doxycycline anhydrous: 0% levocarnitine dinoprostone alprostadil mannitol aminocaproic acid dopamine histamine iodine epinephrine liothyronine nicotine Norepinephrine doxorubicin hydrochloride phenytoin azacitidine acetaminophen allopurinol amantadine diatrizoic acid amifostine amitriptyline amoxapine anagrelide hydrochloride azithromycin betaxolol bicalutamide bretylium tosylate bupivacaine buprenorphine calcitriol cetirizine cevimeline hydrochloride chlorhexidine clindamycin plavix danazol deferiprone demeclocycline desipramine dihydroergotamine dipivefrin hydrochloride dipyridamole docetaxel doxepin droperidol ergocalciferol etoposide felbamate flecainide fluphenazine flumazenil flunisolide flutamide formoterol fumarate foscarnet sodium gentamicin gliclazide glipizide granisetron haloperidol hydrocortisone hydromorphone lidocaine ifosfamide imipramine indomethacin Iohexol iopamidol iothalamic acid ioversol ioxilan irinotecan isoproterenol Isosorbide dinitrate itraconazole ketorolac ketotifen (ketotifen fumarate) linezolid maxaquin loxapine mefenamic acid mepivacaine metformin methylergonovine methylphenidate hydrochloride methylprednisolone metronidazole mexiletine minocycline mitotane tablets modafinil morphine moxifloxacin hydrochloride nalbuphine naloxone naltrexone naphazoline nimodipine nitrofurantoin nortriptyline repaglinide levofloxacin omeprazole oxaliplatin oxaprozin Oxytetracycline pantoprazole pentazocine Pentostatin pentoxifylline perphenazine piroxicam pramipexole dihydrochloride monohydrate prednisolone prednisone Procaine propafenone hydrochloride protriptyline rabeprazole sodium sirolimus riluzole rimantadine ritonavir rivastigmine rizatriptan (rizatriptan benzoate) sevoflurane risedronate sodium succinylcholine sulfisoxazole sulindac sumatriptan (sumatriptan succinate) tamoxifen citrate gatifloxacin temozolomide teniposide thalidomide tirofiban hydrochloride trazodone tretinoin triamcinolone delavirdine mesylate ursodiol zalcitabine zolmitriptan zonisamide phentolamine vincristine diethylpropion Imagent arsenic trioxide estramustine phosphate sodium megestrol isosorbide-5-mononitrate desmopressin acetate estrogens, conjugated fludrocortisone Sincalide oxcarbazepine moricizine nabilone etonogestrel nitazoxanide sufentanil alfentanil cefpodoxime milnacipran fosphenytoin sodium imiquimod rotigotine cidofovir anhydrous rocuronium meropenem gadoteridol invirase Premetrexed adefovir dipivoxil tiludronic acid capecitabine urofollitropin fluticasone propionate trovafloxacin bendamustine acamprosate calcium ropivacaine hydrochloride dofetilide lanreotide enablex rosiglitazone maleate bexarotene paliperidone clofarabine valdecoxib fondaparinux sodium caspofungin (caspofungin acetate) febuxostat posaconazole temsirolimus reyataz palonosetron invanz nepafenac fosaprepitant dimeglumine solifenacin succinate sensipar gadopentetate dimeglumine lubiprostone macugen anidulafungin etravirine prezista nexavar lenalidomide cortisone gadoversetamide ciclesonide micafungin sodium nilotinib (nilotinib hydrochloride monohydrate) thioguanine porfimer sodium sutent sitagliptin (sitagliptin phosphate monohydrate) doxercalciferol entacapone Tolcapone carboprost (carboprost tromethamine) tigecycline olsalazine verteporfin rifapentine ceftobiprole (ceftobiprole medocaril) prasugrel gadofosveset calcitonin salmon cosyntropin forteo prialt bivalirudin glucagon degarelix natrecor

Drugs with this indication epoprostenol sodium dextrose chloride ion estradiol magnesium cation acebutolol (acebutolol hydrochloride) uroxatral amlodipine atenolol atorvastatin calcium benazepril betaxolol bisoprolol fumarate brimonidine verapamil candesartan cilexetil captopril carteolol carvedilol chlorothiazide chlorthalidone cilazapril (cilazapril monohydrate) clonidine diazoxide diltiazem metyrosine trusopt doxazosin doxycycline anhydrous enalapril sodium felodipine fenofibrate fenoldopam fosinopril sodium furosemide guanfacine hydralazine hydrochlorothiazide hydroflumethiazide indapamide irbesartan labetalol latanoprost levobunolol lisinopril losartan Mecamylamine methyldopa metolazone metoprolol minoxidil nadolol nicardipine nifedipine nisoldipine nitroglycerin orlistat paclitaxel phenobarbital phenoxybenzamine phentermine pilocarpine pindolol pioglitazone (pioglitazone hydrochloride) polythiazide pravastatin sodium prazosin propranolol quinapril ephedrine ramipril reserpine meridia sildenafil sotalol hydrochloride spironolactone terazosin timolol trandolapril unoprostone isopropyl valsartan amiloride metipranolol etomidate torsemide treprostinil (treprostinil sodium) moexipril hydrochloride esmolol hydrochloride tamsulosin perindopril erbumine eprosartan (eprosartan mesylate) colestipol telmisartan azopt nebivolol tracleer tadalafil olmesartan medoxomil nitric oxide eplerenone ezetimibe welchol ambrisentan sitaxsentan sodium rosuvastatin calcium travoprost hydroxocobalamin bimatoprost iloprost silodosin tekturna