Vinorelbine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Neutropenia def 4% - 95% x x x x x x
Leukopenia def 6% - 94% x x x x x x x
Agranulocytosis def 80% - 90% x x x x x x
Anaemia def 77% - 83% x x x x x x x
Nausea def 0% - 74% x x x x x x x
Vomiting def 0% - 74% x x x x x x x
Alopecia def 0% - 51% x x x x x x x
Constipation def 0% - 44% x x x x x x x
Neuropathy peripheral def 0% - 44% x x x x x x x
Neuropathy def postmarketing, 0% - 44% x x x x x x x
Injection site reaction def postmarketing, 0% - 38% x x x x x x x
Asthenia def 0% - 36% x x x x x x
Diarrhoea def 0% - 25% x x x x x x x
Hypoaesthesia def 0% - 25% x x x x x x x
Paraesthesia def 0% - 25% x x x x x x x
Local reaction 0% - 22% x x x x x
Pain def postmarketing, 0% - 16% x x x x x x x
Injection site pain 0% - 16% x x x x x x x
Thrombocytopenia def 0% - 15% x x x x x x x
Creatinine increased def 13% x x x x x
Phlebitis def 0% - 10% x x x x x x x
Dyspnoea def postmarketing, 0% - 7% x x x x x x x
Blood bilirubin increased def 5% x x x x
Febrile neutropenia def 4% x x x x x x
Abdominal pain def postmarketing x x x x x x x
Anaphylactic shock def postmarketing x x x x x x x
Angioedema def postmarketing x x x x x x x
Back pain def postmarketing x x x x x x x
Blister def postmarketing x x x x x x
Cough def postmarketing x x
Dysphagia def postmarketing x x x x x x x
Dermatitis def postmarketing x x x x x x x
Oedema def postmarketing x x x x x x x
Oesophagitis def postmarketing x x x x x x x
Rash def postmarketing x x x x x x x
Flushing def postmarketing x x x x x x x
Headache def postmarketing x x x x x x x
Hypersensitivity def postmarketing x x x x x x x
Hypertension def postmarketing x x x x x x x
Hyponatraemia def postmarketing x x x x x x
Hypotension def postmarketing x x x x x x x
Inappropriate antidiuretic hormone secretion def postmarketing x x x x x x x
Musculoskeletal pain def postmarketing x x x x x x
Neoplasm def postmarketing x x x x x x x
Pneumonia def postmarketing x x x x x x x
Pruritus def postmarketing x x x x x x x
Pulmonary oedema def postmarketing x x x x x x x
Pulmonary embolism def postmarketing x x x x x x x
Tachycardia def postmarketing x x x x x x x
Thrombosis def postmarketing x x x x x x x
Urticaria def postmarketing x x x x x x x
Vasodilation def postmarketing x x x x x x x
Venous thrombosis def postmarketing x x x x x x
Deep vein thrombosis def postmarketing x x x x x x
Muscular weakness def postmarketing x x x x x x x
Skin necrosis postmarketing x x x x x
Ache def postmarketing x x x x x x
Mucosal inflammation def postmarketing x x x x x x x
Localized rash postmarketing x x x x x x x
Hypoxemia def postmarketing x x
Thromboembolic event postmarketing x x x x x x x
Embolus def postmarketing x x x x x x x
Weakness def postmarketing x x x x x x x
Anorexia def x x x x x x x
Arrhythmia def x
Arthralgia def x x x x x x
Bronchospasm def x
Cardiovascular disorder def x x x x x x x
Chest pain def x x x x x x x
Cystitis def x x x x x x
Dizziness def x x x x x
Embolism def x x x x x
Extravasation def x
Fatigue def x x x x x x
Body temperature increased def x x x x x x x
Infarction def x x x x x x x
Infection def x x x x x x x
Ischaemia def x x x x x x
Lethargy def x x x x x
Myocardial infarction def x x x x x x x
Necrosis def x
Numbness def x x x x x
Pancreatitis def x x x x x
Ileus paralytic def x
Parity def x
Respiratory tract infection def x x x x x
Stomatitis def x x
Cerebrovascular accident def x x x x
Thrombophlebitis def x
Erythema def x x x x x x x
Vertigo def x x x x x
Weight decreased def x x x x x
Cystitis haemorrhagic x x x x x x
Myocardial ischaemia def x x x x x x
Acute pain def x
Malaise def x x x x x
Myalgia def x x x x x x
Pain in jaw x x x x x x
Sepsis def x x x x x x x
Head and neck cancer def x
Transaminases increased x x x x x
Vein discolouration x x x x x x x
Nephropathy toxic x x x x x
Acute dyspnea x
Myelosuppression def x x x x x x
Neutropenic sepsis x
Myasthenia def x
Pain during injection x x x x x x x
Ileus def x x x x x x
Hepatic insufficiency def x x x x x
Peripheral arterial disease def x
Radiation recall reaction (dermatologic) def x
Indication Labels
Breast cancer def x x
Breast cancer stage IV def x
Cervix carcinoma def x
Death x
Lung neoplasm malignant def x x x x x x x
Metastatic disease def x
Neoplasm malignant def x x x x x x x
Non-small cell lung cancer def x x x x x x
Non-small cell lung cancer metastatic def x x x x x
Non-small cell lung cancer stage III def x x x x x
Ovarian cancer def x
Small cell lung cancer stage unspecified def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: L01CA04

Legend

Color scheme: standardalternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. Vinorelbine : 84 side effects (BC Cancer)
  2. VINORELBINE (VINORELBINE TARTRATE) / VINORELBINE TARTRATE FOR INJECTION : 74 side effects (Health Canada)
  3. vinorelbine tartrate / Navelbine : 92 side effects (FDA CDER)
  4. Vinorelbine : 94 side effects (FDA XML label)
  5. Vinorelbine : 95 side effects (FDA XML label)
  6. VINORELBINE : 95 side effects (FDA XML label)
  7. Vinorelbine : 95 side effects (FDA XML label)