Quetiapine (quetiapine fumarate)

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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Side effect Data for drug Placebo Labels (show all 20)
1 2 3 4 5 6 7 8 9 10
Sedation 25% - 57% 9% - 15% x x x x x x
Somnolence def 18% - 57% 8% - 15% x x x x x x x x x x
Dry mouth def 7% - 44% 0% - 13% x x x x x x x x x x
Headache def 2% - 21% 1% - 14% x x x x x x x x x
Agitation def postmarketing, 0.7% - 20% 0% - 17% x x x x x x x x x
Dizziness def 1% - 18% 0% - 11% x x x x x x x x x x
Fatigue def 3% - 14% 2% - 8% x x x x x
Increased appetite infrequent, 2% - 12% 0% - 6% x x x x x x x
Constipation def 6% - 11% 3% - 6% x x x x x x x x x x
Asthenia def 2% - 10% 1% - 4% x x x x x x
Drooling 0.7% - 8% 0.7% - 5% x x x
Dyskinesia def infrequent, 0% - 8% 0% - 5% x x x x x x
Extrapyramidal disorder def 0.7% - 8% 0% - 5% x x x x x x x x
Movement disorder def 0.7% - 8% 0% - 5% x
Hypertonia def frequent, 0% - 8% 0% - 5% x x x x x x x
Muscle rigidity def 0% - 8% 0% - 5% x x x x x x x x
Nausea def 7% - 8% 4% - 7% x x x x x x x x
Tachycardia def 1% - 8% 0% - 4% x x x x x x x x x
Tremor def 0.7% - 8% 0.7% - 7% x x x x x x x x
Vomiting def 1% - 8% 1% - 6% x x x x x x x
Cogwheel rigidity 0.7% - 8% 0.7% - 5% x x x x x x x
Extrapyramidal symptoms 4% - 8% 1% - 5% x x x x x x x x
Akathisia def 1% - 8% 0% - 5% x x x x x x x x
Dystonia def 0% - 8% 0% - 5% x x x x x x
Hyperkinesia def infrequent, 4% - 8% 4% - 5% x x x x x
Parkinsonian gait 8% 5% x
Tardive dyskinesia def infrequent, 0% - 8% 0% - 5% x x x x
Abdominal pain def 4% - 7% 1% - 3% x x x x x x
Dyspepsia def 2% - 7% 1% - 4% x x x x x x x x x x
Hypotension def 2% - 7% 0% - 5% x x x x x x x x x x
Orthostatic hypotension def 2% - 7% 0% - 5% x x x x x x x x x
Pain def infrequent, 1% - 7% 0% - 5% x x x x x x x x
Weight increased def 3% - 7% 0% - 3% x x x x x x x x x x
Pharyngitis def frequent, 4% - 6% 3% x x
Hypokinesia def 0.7% - 6% 0.7% - 4% x x x x x
Anorexia def frequent x
Back pain def 2% - 5% 1% - 3% x x x x x x x x
Cough def frequent, 3% 1% x x x x
Dysarthria def frequent, 1% - 5% 0% x x x x x x x
Dyspnoea def postmarketing, frequent x x x x
Oedema def rare — 4% 2% x x x x x x x x x
Influenza def frequent, 1% - 2% 0% x x x
Lethargy def 1% - 5% 0% - 2% x x x x
Leukopenia def postmarketing, frequent x x x x x x x x x
Nasal congestion def 3% - 5% 1% - 3% x x x x x
Palpitations def postmarketing — 4% 1% x x x x x x
Rhinitis def frequent, 3% - 4% 1% - 2% x x x x x x x x x
Sweating def frequent, 2% 1% x x x
Oedema peripheral def frequent, 4% 2% x x x x x x x x x
Alanine aminotransferase increased def 5% 1% x x x x x x
Cough increased frequent x x
Anxiety def 2% - 4% 0% - 3% x x x x
Arthralgia def infrequent, 1% - 4% 0% - 2% x x x x x
Rash def infrequent, 4% 2% x x x x x x x x
Gastroenteritis def infrequent, 2% - 4% 0% - 1% x x x x
Irritability def 1% - 4% 0% - 3% x x x x
Viral diarrhoea 4% 1% x x
Muscle twitching def infrequent, 4% 1% x
Vision blurred def 1% - 4% 1% - 2% x x x x x x
Amblyopia def 2% - 3% 1% - 2% x x
Infection def 2% - 3% 0% - 2% x x x x x
Paraesthesia def 3% 2% x x x x x x
Respiratory tract infection def 2% - 3% 2% x x x
Muscle spasms def 1% - 3% 1% x x x x
Speech disorder def 3% 1%
Toothache def 2% - 3% 0% - 1% x x
Upper respiratory tract infection def 2% - 3% 2% x x x
Hormone level abnormal 3% 0%
Aspartate aminotransferase increased def 3% 1% x x x x
Abnormal dreams infrequent, 2% - 3% 0% - 1% x x x
Hypersomnia def 1% - 3% 0% x x x
Choreoathetosis rare, 0% - 2.74% 0% x x
Nuchal rigidity 0% - 2.74% 0% x
Aggression def 2% 1%
Ataxia def infrequent, 2% 0% x
Neck pain def infrequent, 2% 0% x x x
Confusional state def infrequent, 1% - 2% 0% x x x
Libido decreased def rare, 0% - 2% 0% - 1% x x
Dysphagia def infrequent, 2% 0% x x x x x x x
Ear pain def 1% - 2% 0% - 1% x x x x
Body temperature increased def 1% - 2% 0% - 1% x x x x x x x x x
Gastrooesophageal reflux disease def infrequent, 2% 1% x
Seasonal allergy def 2% 1% x
Hyperhidrosis def 2% 1% x x x
Hypersensitivity def 2% 1% x x x x x x x
Hypertension def 1% - 2% 0% - 1% x x x
Hypoaesthesia def 2% 1%
Hypothyroidism def infrequent, 2% 1% x x x x
Pain in extremity def 2% 1% x
Restless legs syndrome def postmarketing, 2% 0% - 1% x x x x x x x
Sinus headache 2% 1% x
Sinusitis def 2% 1% x x
Gastric disorder def 2% 1% x
Syncope def 2% 0% x x x x x
Pollakiuria def infrequent, 2% 1% x x
Urinary tract infection def 2% 0% - 1% x x
Vertigo def infrequent, 2% 1% x x
Migraine def infrequent, 2% 1% x x
Sinus congestion 2% 1% x
Myalgia def 2% 1% x x
Decreased appetite 2% 1% x x x
Disorientation 2% 0% x x
Disturbance in attention 2% 1% x x x
Thinking abnormal infrequent, 2% 0% x
Discomfort def 2% 1% x
Upset stomach 2% 1% x
Stiffness 2% 1% x
Coordination abnormal infrequent, 2% 1% x
Balance disorder 2% 1%
Acne def infrequent, 2% 1% x
Sluggishness 2% 1% x x
Mental disability 2% 0% x x
Abdominal distension def 0% - 1% 0% x
Abscess def 1% 0%
Amenorrhoea def infrequent x
Amnesia def infrequent x
Anaemia def infrequent x
Hypochromic anaemia def infrequent x
Arthritis def infrequent x
Asthma def infrequent x
Blepharitis def infrequent x
Breast feeding def infrequent, 1% 0% x
Bruxism def infrequent x
Bundle branch block def infrequent x
Candidiasis def infrequent x
Vaginal moniliasis infrequent x
Catatonia def infrequent x
Conjunctivitis def infrequent x
Cyanosis def infrequent x
Cystitis def infrequent x
Dehydration def infrequent x
Delusion def infrequent x
Dental caries def infrequent x
Depersonalisation def infrequent x
Dermatitis def rare, infrequent x
Dermatitis contact def infrequent x
Diabetes mellitus def postmarketing, infrequent x x x
Dysgeusia def infrequent, 1% 0% x x x
Dysmenorrhoea def infrequent x
Dysuria def infrequent x
Ear disorder def 1% 0% x
Ecchymosis def infrequent x
Eczema def infrequent x
Eosinophilia def infrequent x x x x x x x
Epistaxis def infrequent x
Faecal incontinence def infrequent x
Flatulence def infrequent, 1% 0% x
Pathological fracture def infrequent x
Gastritis def infrequent x
Gastrointestinal disorder def 1% 0% x x x x x
Gingival bleeding def infrequent x
Gingivitis def infrequent x
Gynaecomastia def rare, infrequent x
Hallucination def infrequent x
Hemiplegia def infrequent x
Haemorrhage def infrequent, 1% 0% x
Haemorrhoids def infrequent x
Hyperglycaemia def postmarketing, infrequent x x x x x
Hyperlipidaemia def infrequent x x x
Hypoglycaemia def infrequent x
Incontinence def infrequent x
Libido increased def infrequent x
Ischaemia def infrequent x
Arthropathy def 1% 0%
Renal failure acute def rare, infrequent x
Cramps of lower extremities infrequent x
Leukocytosis def infrequent x
Leukorrhea def infrequent x
Metrorrhagia def infrequent x
Cramp muscle def infrequent x
Myoclonus def infrequent x
Nocturia def rare, infrequent x
Orchitis def infrequent x
Pelvic pain def infrequent x
Pneumonia def infrequent x
Polyuria def rare, infrequent x
Pruritus def infrequent x
Psychotic disorder def infrequent x x
Renal failure def rare, infrequent x
Salivation def infrequent x
Seborrhoeic dermatitis def infrequent x
Salivary hypersecretion def infrequent x
Skin ulcer def infrequent x
Stomatitis def infrequent x
Cerebrovascular accident def infrequent x
Suicide def infrequent x x
Suicide attempt def infrequent x
Thirst def infrequent x
Thrombophlebitis def rare, infrequent x
Tinnitus def infrequent x
Ulcer def infrequent x
Urinary incontinence def infrequent x
Urinary tract disorder def 1% 0% x x
Vaginal inflammation def infrequent x
Vasodilation def infrequent x
Visual impairment def infrequent x
Vulvovaginitis def infrequent x
Weight decreased def infrequent x x x x
Urinary retention def infrequent x
Chills def infrequent, 1% 0% x x
Stupor def infrequent x
Apathy def infrequent x
Mouth ulceration def infrequent x
Neck stiffness 1% 0% x x x x x
Alcohol intolerance def infrequent x
Creatinine increased def infrequent x
Tongue oedema infrequent
Gamma-glutamyltransferase increased def infrequent, 1% 0% x x x
Manic psychosis infrequent x
Bone pain def infrequent x
Eye pain def infrequent x
Paranoid reaction infrequent x
Phosphatase alkaline increased infrequent x
Electrocardiogram QT prolonged def infrequent x
Deep thrombophlebitis infrequent x
Photosensitivity reaction def infrequent x
Malaise def infrequent x x
Dizziness postural 1% 0% x x x x
Dry throat 1% 0% x x
Erectile dysfunction def infrequent, 1% 0% x x
Rectal haemorrhage def infrequent x
Dry eye infrequent x
Photosensitivity def infrequent x
Pulse irregular def infrequent x
Rash maculo-papular def infrequent x
Movements involuntary def infrequent x
Bradycardia def infrequent x
Lymphadenopathy def infrequent, 1% 0% x
Tooth abscess 1% 0%
Electrocardiogram T wave inversion def infrequent x
Face oedema def infrequent x
Gait disturbance def infrequent x
Cerebral ischaemia def infrequent x
Myasthenia def infrequent x
Abnormal ejaculation infrequent x
Vaginal haemorrhage def infrequent x
Agranulocytosis def postmarketing x x x x
Anaphylactic shock def postmarketing x x x x x x
Angina pectoris def rare x
Aphasia def rare x
Atrial fibrillation def rare x
Atrioventricular block def rare x
Coma def postmarketing x x
Deafness def rare x
Delirium def rare x
Dermatitis exfoliative def rare x
Diabetic ketoacidosis def postmarketing x x
Drug abuse def postmarketing
Glaucoma def rare x
Glossitis def rare x
Glycosuria def rare x
Gout def rare x
Cardiac failure def rare x
Cardiac failure congestive def rare x
Haematemesis def rare x
Haematoma def rare x
Subdural haematoma def rare x
Haemolysis def rare x
Hiccups def rare x
Hyperthyroidism def rare x
Hyperventilation def rare x
Hypokalaemia def rare x
Hyponatraemia def postmarketing x x x x
Body temperature decreased def postmarketing x
Inappropriate antidiuretic hormone secretion def postmarketing x x x x
Intestinal obstruction def rare x
Melaena def rare x
Myocarditis def postmarketing x x x
Neuralgia def rare x
Neutropenia def postmarketing x x x x x x x
Obstruction def rare x
Pancreatitis def rare x
Psoriasis def rare x
Rhabdomyolysis def postmarketing x x x x
Somnambulism def postmarketing x x
Stevens-Johnson syndrome def postmarketing x
Stuttering def rare x
Thrombocytopenia def rare x x
Water intoxication def rare x
Atrioventricular block first degree def rare x
Mood swings rare x
Buccoglossal syndrome rare x
Skin discolouration def rare x
Accommodation disorder rare x
Ketoacidosis postmarketing x x
Cardiac fibrillation rare x
Euphoric mood def rare x
Galactorrhoea postmarketing x x
Edema hands rare x
Dependence physiological def postmarketing
Enlargement abdomen def rare x
Platelet count decreased postmarketing x x x
Electrocardiogram ST segment elevation def rare x
Intoxication rare x
White blood cell count decreased postmarketing x x x x x x
Cardiomyopathy def postmarketing x x x
Diabetic coma def postmarketing x x
Angioedema def x x x x
Bronchitis def
Cardiovascular disorder def x
Central nervous system disorder def
Chest pain def x x
Connective tissue disorder def x x x x
Diarrhoea def x x x x x x
Eye disorder def x x
Fasting def x x
Flushing def
Cardiac disorder def x x x
Hostility def x x
Immune system disorder def x x
Mediastinal disorder def x x
Nasopharyngitis def x
Nervous system disorder def x x x x x
Nervousness def x x
Neuroleptic malignant syndrome def x x x x x x
Night sweats def x
Nightmare def x x x
Nasal disorder def x
Sinus disorder def x
Priapism def x x x x
Respiratory disorder def x x
Seizures def x x x x
Angiopathy def x x x
Akinesia x x x x x
Haemoglobin decreased def x x
Elastosis perforans x x x x x x x x
Abdominal pain upper x
Muscle contractions involuntary x x x
Hepatic enzyme increased x x x
Throat tightness x x x
Protrusion tongue x x x
Blood pressure diastolic decreased x
Suicidal ideation def x
Withdrawn x x x
Electrocardiogram abnormal
Blood glucose increased x
Hot flush def
Regressive behaviour def x x
Drug interaction def x x
Dissecting aortic aneurysm, thoracic x x x
Infestation NOS x x x
Sleep disorder def x
Electrocardiogram change def x x x x
Pharyngolaryngeal pain def x
Insomnia def x x x x x x x x
Malignant syndrome NOS x x x x
High cholesterol def x x
Indication Labels
Adjuvant therapy def x x
Antidepressant therapy x x
Bipolar depression def x
Bipolar disorder def x x x x x x x
Bipolar I disorder x x x x
Bipolar II disorder x x x
Dementia def x x x x
Depressive disorder def x x
Major depression def x x
Mania def x x x x x x x x
Mania acute x x
Mental disorder def x
Schizophrenia def x x x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N05AH04

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. QUETIAPINE : 8 side effects (FDA XML label)
  2. QUETIAPINE (QUETIAPINE FUMARATE) / SANDOZ QUETIAPINE : 38 side effects (Health Canada)
  3. QUETIAPINE FUMARATE / SEROQUEL : 56 side effects (Drugs@FDA)
  4. QUETIAPINE FUMARATE / SEROQUEL XR : 60 side effects (Drugs@FDA)
  5. QUETIAPINE (QUETIAPINE FUMARATE) / CO QUETIAPINE : 66 side effects (Health Canada)
  6. QUETIAPINE (QUETIAPINE FUMARATE) / SEROQUEL XR : 83 side effects (Health Canada)
  7. QUETIAPINE (QUETIAPINE FUMARATE) / RATIO-QUETIAPINE : 86 side effects (Health Canada)
  8. QUETIAPINE : 119 side effects (FDA XML label)
  9. QUETIAPINE : 121 side effects (FDA XML label)
  10. QUETIAPINE FUMARATE / SEROQUEL : 250 side effects (Drugs@FDA)