Gastrooesophageal reflux disease

Definition: A disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is chronic in nature and usually caused by incompetence of the lower esophageal sphincter, and may result in injury to the esophageal mucosal. Symptoms include heartburn and acid indigestion.

Synonyms (terms occurring on more labels are shown first): reflux, gastroesophageal reflux, gastroesophageal reflux disease, GERD, esophageal reflux, gastric reflux, acid reflux, esophageal reflux disease, gastrooesophageal reflux, gastrooesophageal reflux disease, oesophageal reflux, gastro esophageal reflux disease, gastro esophageal reflux

More information: PubMed search and possibly Wikipedia or Medpedia

Proteins predicted to cause Gastrooesophageal reflux disease: CYP3A4, CYP2D6 (2 predictions in total) Show drugs with this side effect as MedDRA Preferred Term

Drugs with this side effect decitabine: 5.05% citalopram: postmarketing, rare, infrequent, frequent ropinirole: infrequent, frequent celecoxib: 4.7% byetta: 2% - 3% fosamax: 0.7% - 2.8% lotronex: 2% quetiapine (quetiapine fumarate): infrequent, 2% topiramate: infrequent, 1% - 2% clomipramine: infrequent risperidone: rare, infrequent rivastigmine: infrequent imatinib mesylate: rare, infrequent aripiprazole: rare, infrequent argatroban: 0.893% bupropion: postmarketing meloxicam: postmarketing memantine hydrochloride: postmarketing naltrexone: postmarketing oxybutynin: postmarketing paroxetine: postmarketing tacrolimus: postmarketing venlafaxine: rare vigabatrin: postmarketing gemifloxacin mesylate: postmarketing frovatriptan: rare bortezomib: postmarketing tadalafil: postmarketing almotriptan: rare misoprostol: postmarketing epoprostenol sodium estradiol theophylline anhydrous cevimeline hydrochloride cyclophosphamide doxepin felbamate fentanyl gliclazide hydromorphone hyoscyamine ibuprofen morphine mycophenolic acid naratriptan nifedipine levofloxacin oxaliplatin pramipexole dihydrochloride monohydrate propafenone hydrochloride rofecoxib sildenafil sumatriptan (sumatriptan succinate) testosterone Thiotepa detrol la tramadol trazodone delavirdine mesylate zolpidem milnacipran imiquimod invirase ultiva tiotropium ibandronate sodium tipranavir bendamustine telmisartan levitra valdecoxib febuxostat posaconazole fosaprepitant dimeglumine lubiprostone varenicline etravirine nexavar lenalidomide nilotinib (nilotinib hydrochloride monohydrate) sutent sitagliptin (sitagliptin phosphate monohydrate) tigecycline methylnaltrexone bromide zelnorm tekturna dabigatran etexilate insulin recombinant human enfuvirtide

Drugs with this indication diatrizoic acid cimetidine famotidine lansoprazole metoclopramide nizatidine omeprazole pantoprazole rabeprazole sodium ranitidine