Oxaliplatin

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 15)
1 2 3 4 5 6 7 8 9 10
Acidosis def postmarketing x x x x x x
Alopecia def postmarketing x x x x x x x
Anaphylactic shock def postmarketing x x x x x x
Anaemia def postmarketing x x x x x x x x
Haemolytic anaemia def postmarketing x x x x
Angioedema def postmarketing x x x x
Coagulopathy def postmarketing x x x x x
Colitis def postmarketing x x x x
Convulsion def postmarketing x x x
Deafness def postmarketing x x x x
Diarrhoea def postmarketing x x x x x x x x x x
Dysarthria def postmarketing x x x x x x
Epistaxis def postmarketing x x x x x
Extravasation def postmarketing x x x x x x
Fasciculation def postmarketing x x x x x
Fibrosis def postmarketing x x x x x
Gastrointestinal haemorrhage def postmarketing x x x x x x
Haematuria def postmarketing x x x x x
Haemolytic uraemic syndrome def postmarketing x x x x x
Haemorrhage def postmarketing x x x x x x x x x
Venoocclusive liver disease def postmarketing x x x x
Hyperbilirubinaemia def postmarketing x x x
Hypokalaemia def postmarketing x x x x x x x x
Infection def postmarketing x x x x x x x
Intestinal obstruction def postmarketing x x x x x
Nephropathy def postmarketing x x x
Renal failure acute def postmarketing x x x
Nephrosis lower nephron def postmarketing x x x
Liver disorder def postmarketing x x x x
Lung disorder def postmarketing x x x x
Nausea def postmarketing x x x x x x x x
Necrosis def postmarketing x x x x x x x x
Nephritis def postmarketing x x x
Nephritis interstitial def postmarketing x x x
Nervous system disorder def postmarketing x x x x x x
Neuritis def postmarketing x x x x x
Neutropenia def postmarketing x x x x x x x x
Obstruction def postmarketing x x x x x x
Optic neuritis def postmarketing x x x x x
Pain def postmarketing x x x x x x
Pancreatitis def postmarketing x x x x x
Neuropathy peripheral def postmarketing x x x x x x x
Pulmonary fibrosis def postmarketing x x x x x
Renal failure def postmarketing x x x
Respiratory disorder def postmarketing x x x x
Shock def postmarketing x x x x
Skin disorder def postmarketing x x x
Stomatitis def postmarketing x x x x x x
Swelling def postmarketing x x x x x
Thrombocytopenia def postmarketing x x x x x x x x
Thromboembolism def postmarketing x x x x x
Vomiting def postmarketing x x x x x x x x x x
Acute interstitial nephritis postmarketing x x x
Cranial nerve paralysis postmarketing x x x x x
Injection site reaction def postmarketing x x x x x x
Renal tubular disorder def postmarketing x x x
Phosphatase alkaline increased postmarketing x x
Prothrombin level increased postmarketing x x x
Interstitial lung disease def postmarketing x x x x
Metabolic acidosis def postmarketing x x x x x x
Visual acuity reduced postmarketing x x x x x x
Neurological symptom postmarketing x x x x x
Diarrhoea, Clostridium difficile postmarketing x x
Sepsis def postmarketing x x x
Nerve paralysis postmarketing x x x x x
Uraemic syndrome postmarketing x x x x x
Redness def postmarketing x x x x x
Mucosal inflammation def postmarketing x x x x x x
Blindness def postmarketing x x x
Paralysis def postmarketing x x x x x x
Febrile neutropenia def postmarketing x x x x x x x
Thromboembolic event postmarketing x x x x
Neutropenic sepsis postmarketing x x x
Ileus def postmarketing x x x x x x
Renal tubular necrosis postmarketing x x x
Cerebral haemorrhage def postmarketing x x x
Abdominal pain def x x x x x x x
Agranulocytosis def x
Anorexia def x x x x x x x
Anxiety def x x x x x
Aphasia def x
Aphonia def x
Arrhythmia def x
Arthralgia def x x x x x x
Ascites def x x
Asphyxia def x
Ataxia def x x x x
Back pain def x x x x x x
Bronchospasm def x x x
Cerebral infarction def x x x
Chest pain def x x x x x
Conjunctivitis def x x x x x
Connective tissue disorder def x
Constipation def x x x x x x
Cough def x x x x x
Cyanosis def x
Dysphagia def x
Dehydration def x x x x x x x
Diplopia def x
Dizziness def x x x x x x
Dysgeusia def x x x x x x
Dyspepsia def x x x x x x
Dyspnoea def x x x x x x x
Dysuria def x x x x x
Oedema def x x x x x x
Rash def x x x x x x
Facial pain def x
Fatigue def x x x x x x
Body temperature increased def x x x x x x x x
Flatulence def x x x x x x
Flushing def x x x x x x
Gastrooesophageal reflux disease def x x x x x
Gastrointestinal disorder def x
Gingivitis def x x
Headache def x x x x x x
Haemolysis def x
Haemoptysis def x x x
Haemorrhoids def x x
Hiccups def x x x x x x
Hoarseness def x
Hypercalcaemia def x
Hyperglycaemia def x x x x x x
Hypersensitivity def x x x x x x x x
Hypertension def x x x
Hypoaesthesia def x
Hypocalcaemia def x x x x x x
Hyponatraemia def x x x x x x
Hypotension def x x x x x x
Immune system disorder def x
Incontinence def x x
Infarction def x x x
Inflammation def x x x x
Laryngospasm def x
Leukopenia def x x x x x
Lymphopenia def x x x x x x
Melaena def x x
Cramp muscle def x
Myoclonus def x
Nervousness def x x
Neuralgia def x x x x x x x
Paraesthesia def x x x x x x x x
Pharyngitis def x x x x x
Pigmentation def x x x
Pneumonia def x x x x x
Proctitis def x x
Ptosis def x
Pruritus def x x x x x
Purpura def x x
Proctalgia def x x x
Retinitis pigmentosa def x
Rhinitis def x x x x x x x
Scotoma def x
Muscle spasms def x
Stridor def x
Suicide def x x x
Sweating def x x x x x
Syncope def x x x x
Tachycardia def x x
Thrombosis def x x x x x x x
Tremor def x
Trigeminal neuralgia def x
Trismus def x
Erythema def x x
Upper respiratory tract infection def x x x x
Pollakiuria def x x x x x
Urinary incontinence def x x
Urticaria def x x x x x
Vertigo def x x x
Visual impairment def x x x x x x
Vocal cord paralysis def x
Weight increased def x x x x
Weight decreased def x x x x x
Wheezing def x
Dry mouth def x x x x x
Oedema peripheral def x x x x
Hepatic function abnormal x
Peripheral sensory neuropathy def x x x x x x x x x
Creatinine increased def x x x x x
Bleeding vaginal def x
Muscular weakness def x x
Bone pain def x x x
Eye pain def x
Dry skin def x x x x x
Sensory disturbance def x x x
Congenital tongue anomaly x
Myalgia def x x x x x
Muscle twitching def x
Chest tightness x
Rectal tenesmus def x x
Disorientation x x
Discomfort def x
Nail changes def x x x
Rash erythematous x
Muscle contractions involuntary x x x
Lacrimation abnormal NOS x x x
Hepatic enzyme increased x
Crocodile tears syndrome x x x x x
Hypoalbuminaemia def x x x x x x
Hypoxia def x x x x
Rectal haemorrhage def x x x
Anaphylactoid reaction x x
Enlargement abdomen def x x
Dysaesthesia def x x x x x x x x
Lacrimation def x x x x x x
Rigors x x x x x x x
Neuropathy def x x x x x x x x
Respiratory distress def x
Coordination abnormal x
Choking sensation x
Gait disturbance def x
Balance disorder x
Hot flush def x
Sweating increased x x x
Catheter infection x x x
Colorectal cancer recurrent def x x x x
Insomnia def x x x x x x
Pulmonary toxicity x x
Dysphasia def x x x x x x
Renal anemia
Respiratory failure def
Death x x x x x x
Dysphonia def x
Eosinophilic pneumonia x x x
Weakness def x x
Rhinitis allergic def x x x x x x
Somnolence def x x
Metastatic neoplasm def x
Vaginal haemorrhage def x x
Indication Labels
Adjuvant therapy def x x x x x x
Breast cancer def x
Carcinoma def x x x x x
Carcinoma colon def x x x x x
Colon cancer def x x x x x x
Colon cancer stage III def x x x x x
Colon cancer stage IV x
Colorectal cancer x x x x x
Colorectal cancer metastatic x
Disease progression def x
Gastric cancer def x
Germ cell cancer x
Head and neck cancer def x
Lung neoplasm malignant def x
Lymphoma def x
Malignant neoplasm of pancreas def x
Mesothelioma def x
Metastatic carcinoma def x
Neoplasm def x x x x x x
Neoplasm malignant def x x x x x x x
Ovarian cancer def x
Prostate cancer def x
Prostatic disorder def x
Rectal disorder def x x x x x
Solid tumour def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: L01XA03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. oxaliplatin / Eloxatin : 11 side effects (FDA CDER)
  2. Oxaliplatin : 26 side effects (BC Cancer)
  3. OXALIPLATIN : 50 side effects (FDA XML label)
  4. oxaliplatin / Eloxatin : 77 side effects (FDA MedWatch)
  5. oxaliplatin for injection / Eloxatin : 97 side effects (FDA MedWatch)
  6. OXALIPLATIN / ELOXATIN : 98 side effects (Health Canada)
  7. Oxaliplatin : 99 side effects (FDA XML label)
  8. OXALIPLATIN / ELOXATIN : 132 side effects (Drugs@FDA)
  9. oxaliplatin / Eloxatin : 149 side effects (FDA CDER)
  10. OXALIPLATIN : 167 side effects (FDA XML label)