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Bupropion

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N06AX12

Side effects

Options: Show MedDRA Preferred Terms,   display all 77 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Nervous system disorder 33.9% 27% x x
Headache postmarketing — 1.1% - 34% 22.2% - 26% x x x x x x x x x x x x x x x x
Gastrointestinal disorder 25.5% x x
Dry mouth 4% - 27.6% 4% - 18.4% x x x x x x x x x x x x x x x x x x x
Weight decreased 23.2% 23.2% x
Sweating increased 22.3% 14.6%
Insomnia 1% - 45% 6% - 21% x x x x x x x x x x x x x
Application site reaction 11% - 17% 7%
Weight increased postmarketing — 13.6% 22.7% x x
Nasopharyngitis 13% 12% x x
Nausea 0.8% - 22.9% 0.3% - 18.9% x x x x x x x x x x x x x x x x x x x
Rhinitis 6.7% - 12% 8% x x x x
Constipation 4% - 26% 2% - 17.3% x x x x x x x x x x x x x x x x
Upper respiratory tract infection 9% 8% x x
Confusional state postmarketing — 8.4% 4.9% x x x x x
Infection rare, 4.7% - 9% 6% x x x x x x x x x x x x
Dizziness 0.5% - 22.3% 5% - 16.2% x x x x x x x x x x x x x x x x
Bradykinesia 8% 8.6%
Diarrhoea 3% - 7% 1% - 8.6% x x x x x x x x x x x x
Anxiety 0.8% - 9% 1.1% - 6% x x x x x x x x x x x x x x x x
Flatulence postmarketing — 1.8% - 6% 3% x x x x x x
Tinnitus postmarketing, 0% - 6% 0% - 2% x x x x x x x x x x x x x x x x x x x
Arrhythmia 5.3% 4.3% x x x
Auditory disorder NOS 5.3% 3.2% x x x
Anorexia 1% - 18.3% 1% - 18.4% x x x x x x x x x x x x x x x x
Fatigue 5% 8.6%
Myoclonus frequent
Nocturia frequent x
Convulsion postmarketing — frequent x x x x x x
Sweating postmarketing — 1.6% - 6% 2% x x x x x x x x x x x x x x x x
Mania frequent x x
Influenza-like symptoms rare, frequent x
Sexual dysfunction frequent
Cough 4% 3% x x
Mediastinal disorder 4% 3% x x
Vomiting postmarketing — 1.6% - 22.9% 2% - 18.9% x x x x x x x x x x x x x x x x
Sensory disturbance 4% 3.2% x x x
Malnutrition 4% 1% x x
Decreased appetite 4% 1% x x
Palpitations 0% - 6% 0% - 2.2% x x x x x x x x x x x x x x x x
Increased appetite 2% - 3.7% 1% - 2.2% x x x x x x
Dyspepsia postmarketing — 3.1% - 4.7% 2.2% x x x x x x x
Influenza 2.4% - 6.2% x x x
Cerebration impaired 3% - 9% 3.8% - 4% x
Abdominal pain 1% - 9% 1% - 2% x x x x x x x x x x x x x x x x
Chest pain infrequent, 1% - 4% 1% x x x x x x x x x x x x x x
Rash postmarketing — 0.8% - 8% 0% - 6.5% x x x x x x x x x x x x x x x x x x x
Nervousness 1% - 5% 2% - 3% x x x x x x x x x x x x
Pain in extremity 2% - 3% 2% x x
Pharyngitis 1.3% - 11% 0% - 2% x x x x x x x x x x x x x x x
Sinusitis 1% - 5% 1% - 4% x x x x x x x x x x x x
Tremor 1% - 21.1% 0% - 7.6% x x x x x x x x x x x x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue 3% 2% x x
Abnormal dreams 3% 2% x x x x x
Vision blurred postmarketing — 2% - 14.6% 2% - 10.3% x x x x x x x x x x
Feeling jittery 3% 2% x x
Ear and labyrinth disorders 3% 1% x x
Pollakiuria postmarketing — 1.3% - 5% 2% - 2.2% x x x x x x x x x x x x x x x x
Amblyopia postmarketing — 1.8% - 3% 2% x x x x
Skin disorder 1.9% - 2.4% x x
Pruritus 1% - 5% 0% - 2% x x x x x x x x x x x x x
Digestion impaired 2.1% x
Arthritis postmarketing, 0% - 3.1% 0% - 2.7% x x x x x x x x x x x x
Asthenia postmarketing — 1.6% - 4% 2% x x x x x x x x x x x x x
Breast disorder 2% 1% x x
Diplopia postmarketing — 2% - 3% 2% x x x x x x x x x x x x x x x x
Dysgeusia 0.3% - 4% 1% - 2% x x x x x x x x x x x x
Dysmenorrhoea 2% 1% x x x x
Irritability postmarketing — 0.5% - 3.9% 2% x x x x x x x x x x x x x
Pain postmarketing — 1.3% - 3% 2% x x x x x x x x x x x x x
Angiopathy 1.86% - 2% 0% x x
Micturition urgency postmarketing — 2% 0% x x x x x x x x x x x
Agitation postmarketing — 0.3% - 31.9% 0.3% - 22.2% x x x x x x x x x x x x
Accidental injury 1% - 2% 1% x x x x
Myalgia postmarketing, 1.6% - 6% 1% - 3% x x x x x x x x x x x x x x x x x x x
Cough increased 1% - 5% 1% x x x x x x x x x x x
Somnolence 2% - 3% 1% - 2% x x x x x x x x x x x x
Muscle spasms 1.9% 3.2%
Migraine postmarketing — 0% - 25.7% 0.3% - 22.2% x x x x x x x x x x x x x x x
Akathisia 1.5% 1.1% x x x
Pseudoparkinsonism 1.5% 1.6%
Neck pain 1% - 2% 0% - 1% x x x x
Arthralgia postmarketing, 0.5% - 5% 1% - 3% x x x x x x x x x x x x x x x x x x x
Flushing postmarketing — 1% - 4% x x x x x x x x x x x x x
Hypersensitivity postmarketing, 1% 0% x x x x x
Paraesthesia postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x x
Urticaria postmarketing, 0% - 2% 0% x x x x x x x x x x x x x x x
Muscle twitching postmarketing — 0.3% - 2% x x x x x x x x x x x x x
Hot flush 0.8% - 3% 0% - 1% x x x x x x x x x x x x
Vaginal haemorrhage 0% - 2% x x x x x x x x x
Hypertension postmarketing, 1% - 4.3% 0% - 1.6% x x x x x x x x x x x x x x x x x x
Back pain postmarketing — 1.8% - 4.5% x x x x
Bronchitis rare — 2% 0% x x x x
Bruxism postmarketing, infrequent x x x x x x x x x x x x x x x x
Libido decreased postmarketing — 0.5% - 3.1% 1.6% x x x x x x x x x x x x x x x
Dysphagia postmarketing — 0% - 2% 0% x x x x x x x x x x x x
Depersonalisation postmarketing, infrequent x x x x x x x x x x x x x x x x
Dyspnoea rare — 0% - 2% 1% x x x x
Oedema postmarketing — frequent x x x x x x x x x x x x x x x x
Frigidity infrequent
Gastrooesophageal reflux disease postmarketing, infrequent x x x x x x x x x x x x x x x
Gingivitis postmarketing, infrequent x x x x x x x x x x x x x x x
Inguinal hernia postmarketing, infrequent x
Hostility postmarketing — 5.6% 3.8% x x x x x x x x x x x x x x x x
Jaundice postmarketing, infrequent x x x x x x x x x x x x x x x x
Polyuria postmarketing, infrequent x x x x x x x x x x x x x x
Psychotic disorder infrequent x x
Stomatitis postmarketing — frequent x x x x x x x x x x x x x x x x
Tachycardia postmarketing — 0.5% - 10.8% 8.6% x x x x x x x x x x x x x x x x
Thirst postmarketing — 1% - 2% 0% x x x x x x x x x x x x x x x
Toothache infrequent x
Urinary tract infection infrequent, 0% - 1.8% x x x x x x x x x x x x
Vertigo postmarketing, infrequent x x x x x x x x x x x x x x
Chills postmarketing — 1.2% 0.5% x x x x x x x x x x x x x x x
Mood swings postmarketing, infrequent x x x x x x x x x x x x x x x
Hepatic function abnormal postmarketing, infrequent x x x x x x x x x x x x x x
Mouth ulceration postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x x
Dry skin postmarketing — 2% 0% x x
Dysphoria postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x
Memory impairment infrequent x
Erectile dysfunction postmarketing — 3.4% 3.1% x x x x x x x x x x x x x x x
Dry eye postmarketing, infrequent x x x x x x x x x x x x x x x
Photosensitivity postmarketing, infrequent x x x x x x x x x x x x x x
Coordination abnormal postmarketing — frequent x x x x x x x x x x x x x x x x
Visual disturbance rare, infrequent x x
Vaginal irritation infrequent x
Irritation gum infrequent x
Paranoia infrequent
Testicular swelling infrequent x
Face oedema postmarketing — 0% - 1% 0% x x x x x x x x x x x x x x x
Aggression postmarketing x x x x x x x x x x x x x x x x x
Alopecia postmarketing, infrequent x x x x x x x x x x x x x x x x
Amnesia postmarketing, rare x x x x x x x x x x x x x x x
Anaemia postmarketing, rare x x x x x x x x x x x x x x x x x x
Angioedema postmarketing x x x x x x x x x x x x x x x x x x
Aphasia postmarketing, rare x x x x x x x x x x x x x x x
Ataxia postmarketing — frequent x x x x x x x x x x x x x x x x x
Bronchospasm postmarketing, rare x x x x x x x x x x x x x x x x
Cardiovascular disorder postmarketing x
Colitis postmarketing, rare x x x x x x x x x x x x x x x x
Coma postmarketing x x x x x x x x x x x x x x x x x x
Cystitis postmarketing, rare x x x x x x x x x x x x x x x
Deafness postmarketing x x x x x x x x x x x x x x
Delirium postmarketing x x x x x x x x x x x x x x x x x x
Delusion postmarketing, 1.2% 1.1% x x x x x x x x x x x x x x
Dermatitis exfoliative postmarketing x x x x x x x x x x x x x x x x x x
Dysarthria postmarketing, infrequent x x x x x x x x x x x x x x x
Dyskinesia postmarketing, frequent x x x x x x x x x x x x x x x
Dysuria postmarketing, rare x x x x x x x x x x x x x x x x
Ecchymosis postmarketing, infrequent x x x x x x x x x x x x x x x x x x
Enuresis rare x
Epistaxis rare, 1% - 2% 0% x x x
Erythema multiforme postmarketing x x
Oesophagitis postmarketing x x x x x x x x x x x x x x x x x x
Extrapyramidal disorder postmarketing x x x x x x x x x x x x x x x
Body temperature increased postmarketing — 1% - 2% 0.5% x x x x x x x x x x x x x x x x x x x
Gastrointestinal haemorrhage postmarketing, rare x x x x x x x x x x x x x x x x
Gingival bleeding postmarketing x x x x x x x x x x x x x x x
Angle closure glaucoma postmarketing x
Glossitis postmarketing — infrequent x x x x x x x x x x x x x x x
Glycosuria postmarketing, rare x x x x x x x x x x x x x x x x
Gynaecomastia postmarketing, infrequent x x x x x x x x x x x x x x x x
Hallucination postmarketing, frequent x x x x x x x x x x x x x x
Hepatitis postmarketing x x x x x x x x x x x x x x x x x x
Hirsutism postmarketing, rare x x x x x x x x x x x x x x x x
Hyperglycaemia postmarketing x x x x x x x x x x x x x x x x x x
Type IV hypersensitivity reaction postmarketing x x x x x x x x x x x x x x x x x x
Hypoaesthesia postmarketing, infrequent x x x x x x x x x x x x x x x
Hypoglycaemia postmarketing x x x x x x x x x x x x x x x x x
Hypotension postmarketing, 2.5% 2.2% x x x x x x x x x x x x x x x
Orthostatic hypotension postmarketing, infrequent x x x x x x x x x x x x x x x x x x x
Inappropriate antidiuretic hormone secretion postmarketing x x x x x x x x x x x x x x x x x x
Libido increased postmarketing, frequent x x x x x x x x x x x x x x x
Intestinal perforation postmarketing, rare x x x x x x x x x x x x x x x x
Cramps of lower extremities postmarketing — 0.2% - 1% x x x x x x x x x x x x x x
Leukocytosis postmarketing x x x x x x x x x x x x x x x x x x
Leukopenia postmarketing x x x x x x x x x x x x x x x x x x
Menopause postmarketing, rare x x x x x x x x x x x x x x x
Hypertonia postmarketing — 0.5% - 1.2% x x x x x x x x x x x x x x x
Muscle rigidity postmarketing x x x x x x x x x x x x x x x x x x
Mydriasis postmarketing, infrequent x x x x x x x x x x x x x x x
Myocardial infarction postmarketing, rare x x x x x x x x x x x x x x x x
Neuralgia postmarketing x x x x x x x x x x x x x x x
Ovarian disorder rare x
Pallor rare x
Pancreatitis postmarketing x x x x x x x x x x x x x x x
Pancytopenia postmarketing, rare x x x x x x x x x x x x x x x x x x
Pelvic infection rare x
Phlebitis postmarketing, rare x x x x x x x x x x x x x x x x
Pneumonia postmarketing, rare x x x x x x x x x x x x x x x
Prostatic disorder postmarketing, infrequent x x x x x x x x x x x x x x x
Pulmonary embolism postmarketing, rare x x x x x x x x x x x x x x x x
Rhabdomyolysis postmarketing x x x x x x x x x x x x x x x x x x
Salpingitis postmarketing x x x x x x x x x x x x x x x
Sciatica rare
Serum sickness postmarketing x x x x x x x x x x x x x x x x x x
Salivary hypersecretion postmarketing, infrequent x x x x x x x x x x x x x x x
Stevens-Johnson syndrome postmarketing x x x x x x
Gastric ulcer postmarketing, rare x x x x x x x x x x x x x x x x
Cerebrovascular accident postmarketing, infrequent x x x x x x x x x x x x x x x
Suicide attempt postmarketing x x x x x x x x
Syncope postmarketing — 1.2% 0.5% x x x x x x x x x x x x x x x x x
Thrombocytopenia postmarketing x x x x x x x x x x x x x x x x x x
Urinary incontinence postmarketing, rare x x x x x x x x x x x x x x x x
Urinary tract disorder postmarketing x
Vaginal inflammation postmarketing x x x x x x x x x x x x x x
Vasodilation postmarketing, infrequent x x x x x x x x x x x x x x x
Urinary retention postmarketing, 1.9% 2.2% x x x x x x x x x x x x x x x
Body odor rare x
Akinesia postmarketing, 8% 8.6% x x x x x x x x x x x x x x x
Oedema peripheral postmarketing, infrequent x x x x x x x x x x x x x x
Hypokinesia postmarketing x x x x x x x x x x x x x x x
Atrioventricular block complete postmarketing x x x x x x x x x x x x x x x x x
Tongue oedema postmarketing, rare x x x x x x x x x x x x x x x x
Electroencephalogram abnormal postmarketing x x x x x x x x x x x x x x x
Hepatocellular injury postmarketing, infrequent x x x x x x x x x x x x x x x x
Manic psychosis postmarketing x x x x x x x x x x x x x x
Muscular weakness postmarketing x x x x x x x x x x x x x x x x x
Paranoid reaction postmarketing x x
Malaise postmarketing, rare x x x x x x x x x x x x x x x
Derealisation postmarketing, rare x x x x x x x x x x x x x x x x
Painful erection postmarketing, infrequent x x x x x x x x x x x x x x x x
Intraocular pressure increased postmarketing x x x x x x x x x x x x x x
Euphoric mood postmarketing, 1.2% 0.5% x x x x x x x x x x x x x x
Swollen tongue postmarketing, rare x x x x x x x x x x x x x x x x
Impairment of attention rare
Hypomania postmarketing — frequent x x x x x x x x x x x x x x x x
Painful ejaculation rare x
Extrasystoles postmarketing, infrequent x x x x x x x x x x x x x x x x
Rash maculo-papular postmarketing, rare x x x x x x x x x x x x x
Suicidal ideation postmarketing — infrequent x x x x x x x x x
Hyperkinesia postmarketing, infrequent x x x x x x x x x x x x x x x
Neuropathy postmarketing x x x x x x x x x x x x x x x
Hair colour changes rare x
Musculoskeletal chest pain postmarketing — infrequent x x x x x x x x x x x x x x x x
Lymphadenopathy postmarketing, rare x x x x x x x x x x x x x x x x x
Tardive dyskinesia postmarketing x x x x x x x x x x x x x x x x x
Completed suicide postmarketing x x x x x x x x x x x x x
Neurological examination abnormal rare
Dyspareunia postmarketing, rare x x x x x x x x x x x x x x x x
Abnormal ejaculation postmarketing x x x x x x x x x x x x x x x
Abdominal distension
Amenorrhoea
Anaphylactic shock x
Anger
Asthma
Back injury
Mental disorder
Bipolar disorder
Concussion
Breast cancer
Bursitis
Basal cell carcinoma
Carpal tunnel syndrome
Pleuritic pain
Chest wall pain
Conjunctivitis
Connective tissue disorder x x
Contusion
Cyst
Dehydration
Dental caries
Dermatitis atopic
Drug abuse
Drug hypersensitivity
Ear pain
Eczema
Epicondylitis
Eructation
Excoriation
Eye disorder
Flank pain
Vitreous floaters
Cardiac flutter
Localised infection
Folliculitis
Food allergy
Food poisoning
Gastritis
Gastroenteritis
Breath odour
Seasonal allergy
Cardiac disorder
Haemorrhage x
Hepatitis C
Herpes zoster
Herpes virus infection
Hordeolum
Hunger
Hypercholesterolaemia
Hyperhidrosis
Hypertrophy of breast
Hyperventilation
Hypotrichosis
Immune system disorder
Keratoconjunctivitis sicca
Laryngitis
Lethargy
Menstrual disorder
Metrorrhagia
Motion sickness
Cramp muscle
Hypotonia
Musculoskeletal disorder
Musculoskeletal pain
Fungal infection
Nasal congestion
Neoplasm
Night sweats
Nightmare
Orgasm abnormal
Osteoporosis
Ovarian cyst
Panic reaction
Sinus disorder
Polyp
Pregnancy
Premenstrual syndrome
Prurigo
Tension headache
Hyperacusis
Respiratory tract infection
Sebaceous gland disorder
Pharyngitis streptococcal
Sinus headache
Sleep disturbance x x x
Sneezing
Snoring
Soft tissue injury
Somnambulism
Suicide x x
Sunburn
Supraventricular tachycardia
Taste disorders x
Tendonitis
Testicular pain
Tinea pedis
Tonsillitis
Tooth disorder x x
Trichotillomania
Micturition disorder
Wheezing
Wound infection
Laceration
Yawning
Muscle strain
Vaginitis bacterial
Apathy
Photophobia
Depressive symptom
Panic attack
Withdrawal symptom x
Swelling face
Impaired healing
Hyperchlorhydria
Eye pain
Urethral pain
Tendon disorder
Duodenal ulcer haemorrhage
Sinus congestion
Skin irritation
Joint swelling
Lacrimation increased
Viral diarrhoea
Menstruation irregular
Facial bones fracture
Joint stiffness
Photosensitivity reaction
Oral pain
Nasal dryness
Cold sweat
Abdominal pain upper
Abdominal pain lower
Disorientation
Disturbance in attention
Affect lability
Feeling of despair
Tension
Thinking abnormal
Perseveration
Hallucination, auditory
Rash erythematous
Muscle contractions involuntary
Difficulty sleeping
Upset stomach
Hepatotoxicity
Chest discomfort
Lacrimation decreased
Hepatic enzyme increased x
Pain in jaw
Heart rate irregular
Circumoral oedema
Genital rash
Gingival pain
Frequent bowel movements
Nipple pain
Prostate infection
Dermal cyst
Pulmonary congestion
Parkinsonism x
Breast tenderness
Vocal cord disorder
Mouth injury
Nerve compression
Peripheral coldness
Viral upper respiratory tract infection
Depressed mood
Gastric irritation
Shakiness
Initial insomnia
Middle insomnia
Joint injury
Increased tendency to bruise
Rigors
Respiratory sighs
Defaecation urgency
Joint sprain
Wrist fracture
Energy increased
Pruritus generalised
Dyslexia
Conjunctivitis infective
Blood pressure increased x
Tooth abscess
Breast microcalcification
Paraesthesia oral
Hypoaesthesia oral
Influenza like illness
Stress symptoms
Self-injurious ideation
Sinus pain
Terminal insomnia
Depressed level of consciousness
Vaginal mycosis
Lip dry
Skin laceration
Renal pain
Gastritis viral
Latex allergy
Sore eye
Sensation of heaviness
Gastrointestinal pain
Ear infection
Throat irritation
Acne
Limb injury
Infestation NOS x x
Sleep disorder
Animal scratch
Arthropod bite
Feelings of worthlessness
Social avoidant behaviour
Disturbance in sexual arousal
Pharyngolaryngeal pain
Tooth infection
Injection site joint pain
Post procedural pain
Muscle tightness
Hypertonic bladder
Hypersomnia
Respiratory tract congestion
Musculoskeletal stiffness
Gastrointestinal discomfort
Infrequent bowel movements
Rhinorrhoea
Increased upper airway secretion
Feeling abnormal
Parosmia
Lower limb fracture
Sore mouth
Appetite absent
Loose stools
Feeling hot

Indications

Information about indications was extracted from the indications and usage sections of the labels.

BUPROPION

Side effects:8
Source:FDA Structured Product Label

BUPROPION

Side effects:47
Source:FDA Structured Product Label

BUPROPION

Side effects:48
Source:FDA Structured Product Label

BUPROPION

Side effects:92
Source:FDA Structured Product Label

BUPROPION

Side effects:136
Source:FDA Structured Product Label

BUPROPION

Side effects:145
Source:FDA Structured Product Label

BUPROPION

Side effects:146
Source:FDA Structured Product Label

BUPROPION

Side effects:149
Source:FDA Structured Product Label

BUPROPION

Side effects:158
Source:FDA Structured Product Label

BUPROPION

Side effects:159
Source:FDA Structured Product Label

BUPROPION

Side effects:160
Source:FDA Structured Product Label

BUPROPION

Side effects:160
Source:FDA Structured Product Label

BUPROPION

Side effects:162
Source:FDA Structured Product Label

BUPROPION

Side effects:163
Source:FDA Structured Product Label

BUPROPION HYDROCHLORIDE / RATIO-BUPROPION SR

Side effects:166
Source:Health Canada

BUPROPION

Side effects:167
Source:FDA Structured Product Label

BUPROPION HYDROCHLORIDE / ZYBAN

Side effects:175
Source:FDA

BUPROPION

Side effects:187
Source:FDA Structured Product Label

BUPROPION

Side effects:188
Source:FDA Structured Product Label

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label