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Bupropion

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N06AX12

Side effects

Options: Hide MedDRA Preferred Terms ,   display all 77 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Nervous system disorder Nervous system disorder 33.9% 27% x x x
Headache Headache postmarketing — 1.1% - 34% 22.2% - 26% x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder 25.5% x x x
Digestion impaired 2.1% x x
Dry mouth Dry mouth 4% - 27.6% 4% - 18.4% x x x x x x x x x x x x x x x x x x x
Weight decreased Weight decreased 23.2% 23.2% x
Hyperhidrosis Sweating increased 22.3% 14.6% x
Sweating postmarketing — 1.6% - 6% 2% x x x x x x x x x x x x x x x
Hyperhidrosis
Insomnia Insomnia 1% - 45% 6% - 21% x x x x x x x x x x x x x x
Difficulty sleeping
Application site reaction Application site reaction 11% - 17% 7% x x
Weight increased Weight increased postmarketing — 13.6% 22.7% x x
Nasopharyngitis Nasopharyngitis 13% 12% x x x
Rhinorrhoea
Nausea Nausea 0.8% - 22.9% 0.3% - 18.9% x x x x x x x x x x x x x x x x x x x
Rhinitis Rhinitis 6.7% - 12% 8% x x x x x
Constipation Constipation 4% - 26% 2% - 17.3% x x x x x x x x x x x x x x x x x x
Upper respiratory tract infection Upper respiratory tract infection 9% 8% x x x
Confusional state Confusional state postmarketing — 8.4% 4.9% x x x x x x x x x
Feeling abnormal Confusional state postmarketing — 8.4% 4.9% x x x x x x x x x
Malaise postmarketing, rare x x x x x x x x x x x x x x
Feeling abnormal
Infection Infection rare, 4.7% - 9% 6% x x x x x x x x x x x
Dizziness Dizziness 0.5% - 22.3% 5% - 16.2% x x x x x x x x x x x x x x x x
Syncope postmarketing — 1.2% 0.5% x x x x x x x x x x x x x x x x x
Bradykinesia Bradykinesia 8% 8.6%
Diarrhoea Diarrhoea 3% - 7% 1% - 8.6% x x x x x x x x x x x x x
Loose stools
Anxiety Anxiety 0.8% - 9% 1.1% - 6% x x x x x x x x x x x x x x x x
Flatulence Flatulence postmarketing — 1.8% - 6% 3% x x x x x x
Tinnitus Tinnitus postmarketing, 0% - 6% 0% - 2% x x x x x x x x x x x x x x x x x x x
Arrhythmia Arrhythmia 5.3% 4.3% x x x x x
Hearing impaired Auditory disorder NOS 5.3% 3.2% x x x x x
Decreased appetite Anorexia 1% - 18.3% 1% - 18.4% x x x x x x x x x x x x x x x x
Decreased appetite 4% 1% x x x
Appetite absent
Asthenia Fatigue 5% 8.6%
Asthenia postmarketing — 1.6% - 4% 2% x x x x x x x x x x x x x x
Fatigue Fatigue 5% 8.6%
Myoclonus Myoclonus frequent x x
Nocturia Nocturia frequent x x
Convulsion Convulsion postmarketing — frequent x x x x x x x x x x
Mania Mania frequent x x x x x
Manic psychosis postmarketing x x x x x x x x x x x x x
Influenza like illness Influenza-like symptoms rare, frequent x x
Influenza like illness
Sexual dysfunction Sexual dysfunction frequent x x
Cough Cough 4% 3% x x x
Cough increased 1% - 5% 1% x x x x x x x x x x x x
Mediastinal disorder Mediastinal disorder 4% 3% x x x
Vomiting Vomiting postmarketing — 1.6% - 22.9% 2% - 18.9% x x x x x x x x x x x x x x x x x x
Sensory disturbance Sensory disturbance 4% 3.2% x x x x x
Malnutrition Malnutrition 4% 1% x x x
Palpitations Palpitations 0% - 6% 0% - 2.2% x x x x x x x x x x x x x x x x
Increased appetite Increased appetite 2% - 3.7% 1% - 2.2% x x x x x x x x x
Dyspepsia Dyspepsia postmarketing — 3.1% - 4.7% 2.2% x x x x x x x x x x
Digestion impaired 2.1% x x
Influenza Influenza 2.4% - 6.2% x x
Disturbance in attention Cerebration impaired 3% - 9% 3.8% - 4% x x x
Impairment of attention rare x x
Disturbance in attention
Mental disability Cerebration impaired 3% - 9% 3.8% - 4% x x x
Thinking abnormal
Abdominal pain Abdominal pain 1% - 9% 1% - 2% x x x x x x x x x x x x x x x
Gastrointestinal pain Abdominal pain 1% - 9% 1% - 2% x x x x x x x x x x x x x x x
Gastrointestinal pain
Chest pain Chest pain infrequent, 1% - 4% 1% x x x x x x x x x x x x x x x x
Chest discomfort
Dermatitis Rash postmarketing — 0.8% - 8% 0% - 6.5% x x x x x x x x x x x x x x x x x x x
Rash Rash postmarketing — 0.8% - 8% 0% - 6.5% x x x x x x x x x x x x x x x x x x x
Nervousness Nervousness 1% - 5% 2% - 3% x x x x x x x x x x x x x
Feeling jittery 3% 2% x x x
Tension Nervousness 1% - 5% 2% - 3% x x x x x x x x x x x x x
Tension
Pain in extremity Pain in extremity 2% - 3% 2% x x x
Pharyngitis Pharyngitis 1.3% - 11% 0% - 2% x x x x x x x x x x x x x x
Sinusitis Sinusitis 1% - 5% 1% - 4% x x x x x x x x x x x x x
Tremor Tremor 1% - 21.1% 0% - 7.6% x x x x x x x x x x x x x x x x x x x
Shakiness
Skin disorder Unspecified disorder of skin and subcutaneous tissue 3% 2% x x x
Skin disorder 1.9% - 2.4% x x x x
Abnormal dreams Abnormal dreams 3% 2% x x x x x
Vision blurred Vision blurred postmarketing — 2% - 14.6% 2% - 10.3% x x x x x x x x x x x
Feeling jittery Feeling jittery 3% 2% x x x
Pollakiuria Pollakiuria postmarketing — 1.3% - 5% 2% - 2.2% x x x x x x x x x x x x x x x x
Micturition urgency postmarketing — 2% 0% x x x x x x x x x x x x
Amblyopia Amblyopia postmarketing — 1.8% - 3% 2% x x x
Pruritus Pruritus 1% - 5% 0% - 2% x x x x x x x x x x x x x x x
Arthritis Arthritis postmarketing, 0% - 3.1% 0% - 2.7% x x x x x x x x x x x x x x
Breast disorder Breast disorder 2% 1% x x x
Diplopia Diplopia postmarketing — 2% - 3% 2% x x x x x x x x x x x x x x x x
Dysgeusia Dysgeusia 0.3% - 4% 1% - 2% x x x x x x x x x x x x x
Dysmenorrhoea Dysmenorrhoea 2% 1% x x x x
Irritability Irritability postmarketing — 0.5% - 3.9% 2% x x x x x x x x x x x x x x
Pain Pain postmarketing — 1.3% - 3% 2% x x x x x x x x x x x x x
Angiopathy Angiopathy 1.86% - 2% 0% x x x
Micturition urgency Micturition urgency postmarketing — 2% 0% x x x x x x x x x x x x
Agitation Agitation postmarketing — 0.3% - 31.9% 0.3% - 22.2% x x x x x x x x x x x x x
Hyperkinesia postmarketing, infrequent x x x x x x x x x x x x x x
Injury Accidental injury 1% - 2% 1% x x x x x
Myalgia Myalgia postmarketing, 1.6% - 6% 1% - 3% x x x x x x x x x x x x x x x x x x x
Musculoskeletal discomfort Myalgia postmarketing, 1.6% - 6% 1% - 3% x x x x x x x x x x x x x x x x x x x
Arthralgia postmarketing, 0.5% - 5% 1% - 3% x x x x x x x x x x x x x x x x x x x
Somnolence Somnolence 2% - 3% 1% - 2% x x x x x x x x x x x x x
Muscle spasms Muscle spasms 1.9% 3.2%
Cramps of lower extremities postmarketing — 0.2% - 1% x x x x x x x x x x x x x
Cramp muscle
Migraine Migraine postmarketing — 0% - 25.7% 0.3% - 22.2% x x x x x x x x x x x x x x x x x
Akathisia Akathisia 1.5% 1.1% x x x x x
Parkinsonism Pseudoparkinsonism 1.5% 1.6%
Parkinsonism x
Neck pain Neck pain 1% - 2% 0% - 1% x x x x x
Arthralgia Arthralgia postmarketing, 0.5% - 5% 1% - 3% x x x x x x x x x x x x x x x x x x x
Flushing Flushing postmarketing — 1% - 4% x x x x x x x x x x x x x x x
Hypersensitivity Hypersensitivity postmarketing, 1% 0% x x x x x x
Paraesthesia Paraesthesia postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x x x x
Urticaria Urticaria postmarketing, 0% - 2% 0% x x x x x x x x x x x x x x x x x
Muscle twitching Muscle twitching postmarketing — 0.3% - 2% x x x x x x x x x x x x x x
Menopausal symptoms Hot flush 0.8% - 3% 0% - 1% x x x x x x x x x x x x x
Hot flush Hot flush 0.8% - 3% 0% - 1% x x x x x x x x x x x x x
Vaginal haemorrhage Vaginal haemorrhage 0% - 2% x x x x x x x x
Hypertension Hypertension postmarketing, 1% - 4.3% 0% - 1.6% x x x x x x x x x x x x x x x x x x
Back pain Back pain postmarketing — 1.8% - 4.5% x x x
Bronchitis Bronchitis rare — 2% 0% x x x x x x
Bruxism Bruxism postmarketing, infrequent x x x x x x x x x x x x x x x x
Libido decreased Libido decreased postmarketing — 0.5% - 3.1% 1.6% x x x x x x x x x x x x x x x
Disturbance in sexual arousal Libido decreased postmarketing — 0.5% - 3.1% 1.6% x x x x x x x x x x x x x x x
Libido increased postmarketing, frequent x x x x x x x x x x x x x x x x
Disturbance in sexual arousal
Dysphagia Dysphagia postmarketing — 0% - 2% 0% x x x x x x x x x x x x x x
Depersonalisation Depersonalisation postmarketing, infrequent x x x x x x x x x x x x x x x x x
Dyspnoea Dyspnoea rare — 0% - 2% 1% x x x x x x x
Oedema Oedema postmarketing — frequent x x x x x x x x x x x x x x x x
Female sexual arousal disorder Frigidity infrequent x x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease postmarketing, infrequent x x x x x x x x x x x x x x
Gingivitis Gingivitis postmarketing, infrequent x x x x x x x x x x x x x x
Inguinal hernia Inguinal hernia postmarketing, infrequent x x x
Hostility Hostility postmarketing — 5.6% 3.8% x x x x x x x x x x x x x x x x
Jaundice Jaundice postmarketing, infrequent x x x x x x x x x x x x x x x x
Polyuria Polyuria postmarketing, infrequent x x x x x x x x x x x x x
Urine output increased Polyuria postmarketing, infrequent x x x x x x x x x x x x x
Psychotic disorder Psychotic disorder infrequent x x x x x
Paranoia infrequent x x
Stomatitis Stomatitis postmarketing — frequent x x x x x x x x x x x x x x x x
Mouth ulceration postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x
Tachycardia Tachycardia postmarketing — 0.5% - 10.8% 8.6% x x x x x x x x x x x x x x x x
Thirst Thirst postmarketing — 1% - 2% 0% x x x x x x x x x x x x x x x
Toothache Toothache infrequent x x
Urinary tract infection Urinary tract infection infrequent, 0% - 1.8% x x x x x x x x x x x x
Vertigo Vertigo postmarketing, infrequent x x x x x x x x x x x x x x x
Chills Chills postmarketing — 1.2% 0.5% x x x x x x x x x x x x x x x
Rigors
Mood swings Mood swings postmarketing, infrequent x x x x x x x x x x x x x x
Affect lability Mood swings postmarketing, infrequent x x x x x x x x x x x x x x
Affect lability
Hepatic function abnormal Hepatic function abnormal postmarketing, infrequent x x x x x x x x x x x x x
Mouth ulceration Mouth ulceration postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x
Dry skin Dry skin postmarketing — 2% 0% x x x x
Dysphoria Dysphoria postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x x
Memory impairment Memory impairment infrequent x x x
Erectile dysfunction Erectile dysfunction postmarketing — 3.4% 3.1% x x x x x x x x x x x x x x x
Dry eye Dry eye postmarketing, infrequent x x x x x x x x x x x x x x
Keratoconjunctivitis sicca
Photosensitivity reaction Photosensitivity postmarketing, infrequent x x x x x x x x x x x x x
Sunburn
Photosensitivity reaction
Coordination abnormal Coordination abnormal postmarketing — frequent x x x x x x x x x x x x x x x x x
Visual impairment Visual disturbance rare, infrequent x x x
Vulvovaginal discomfort Vaginal irritation infrequent x x
Gingival pain Irritation gum infrequent x x
Gingival pain
Paranoia Paranoia infrequent x x
Paranoid reaction postmarketing x x
Testicular swelling Testicular swelling infrequent x x
Face oedema Face oedema postmarketing — 0% - 1% 0% x x x x x x x x x x x x x x
Aggression Aggression postmarketing x x x x x x x x x x x x x x x x x
Alopecia Alopecia postmarketing, infrequent x x x x x x x x x x x x x x x x
Amnesia Amnesia postmarketing, rare x x x x x x x x x x x x x x
Anaemia Anaemia postmarketing, rare x x x x x x x x x x x x x x x x x
Angioedema Angioedema postmarketing x x x x x x x x x x x x x x x x x x
Aphasia Aphasia postmarketing, rare x x x x x x x x x x x x x x x
Ataxia Ataxia postmarketing — frequent x x x x x x x x x x x x x x x x x x
Bronchospasm Bronchospasm postmarketing, rare x x x x x x x x x x x x x x x
Cardiovascular disorder Cardiovascular disorder postmarketing x x x
Colitis Colitis postmarketing, rare x x x x x x x x x x x x x x x
Coma Coma postmarketing x x x x x x x x x x x x x x x x x x
Cystitis Cystitis postmarketing, rare x x x x x x x x x x x x x x x
Bladder pain Cystitis postmarketing, rare x x x x x x x x x x x x x x x
Cystitis noninfective Cystitis postmarketing, rare x x x x x x x x x x x x x x x
Deafness Deafness postmarketing x x x x x x x x x x x x x
Delirium Delirium postmarketing x x x x x x x x x x x x x x x x x x
Delusion Delusion postmarketing, 1.2% 1.1% x x x x x x x x x x x x x
Dermatitis exfoliative Dermatitis exfoliative postmarketing x x x x x x x x x x x x x x x x x x
Dysarthria Dysarthria postmarketing, infrequent x x x x x x x x x x x x x x x x
Osteoarthritis Dysarthria postmarketing, infrequent x x x x x x x x x x x x x x x x
Dyskinesia Dyskinesia postmarketing, frequent x x x x x x x x x x x x x x x x
Dysuria Dysuria postmarketing, rare x x x x x x x x x x x x x x x
Ecchymosis Ecchymosis postmarketing, infrequent x x x x x x x x x x x x x x x x x x
Enuresis Enuresis rare x x
Epistaxis Epistaxis rare, 1% - 2% 0% x x x x x
Erythema multiforme Erythema multiforme postmarketing x x
Stevens-Johnson syndrome postmarketing x x x x x x x x
Oesophagitis Oesophagitis postmarketing x x x x x x x x x x x x x x x x x x
Extrapyramidal disorder Extrapyramidal disorder postmarketing x x x x x x x x x x x x x x
Body temperature increased Body temperature increased postmarketing — 1% - 2% 0.5% x x x x x x x x x x x x x x x x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage postmarketing, rare x x x x x x x x x x x x x x x
Gingival bleeding Gingival bleeding postmarketing x x x x x x x x x x x x x x
Angle closure glaucoma Angle closure glaucoma postmarketing x x
Glossitis Glossitis postmarketing — infrequent x x x x x x x x x x x x x
Glycosuria Glycosuria postmarketing, rare x x x x x x x x x x x x x x x x
Gynaecomastia Gynaecomastia postmarketing, infrequent x x x x x x x x x x x x x x x x
Hallucination Hallucination postmarketing, frequent x x x x x x x x x x x x x x x
Hepatitis Hepatitis postmarketing x x x x x x x x x x x x x x x x x x
Hirsutism Hirsutism postmarketing, rare x x x x x x x x x x x x x x x
Hyperglycaemia Hyperglycaemia postmarketing x x x x x x x x x x x x x x x x x x
Type IV hypersensitivity reaction Type IV hypersensitivity reaction postmarketing x x x x x x x x x x x x x x x x x x
Hypoaesthesia Hypoaesthesia postmarketing, infrequent x x x x x x x x x x x x x x
Hypoglycaemia Hypoglycaemia postmarketing x x x x x x x x x x x x x x x x x
Hypotension Hypotension postmarketing, 2.5% 2.2% x x x x x x x x x x x x x x x
Orthostatic hypotension Orthostatic hypotension postmarketing, infrequent x x x x x x x x x x x x x x x x x x x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion postmarketing x x x x x x x x x x x x x x x x x x
Libido increased Libido increased postmarketing, frequent x x x x x x x x x x x x x x x x
Intestinal perforation Intestinal perforation postmarketing, rare x x x x x x x x x x x x x x x x
Leukocytosis Leukocytosis postmarketing x x x x x x x x x x x x x x x x x x
Leukopenia Leukopenia postmarketing x x x x x x x x x x x x x x x x x x
Menopause Menopause postmarketing, rare x x x x x x x x x x x x x x
Hypertonia Hypertonia postmarketing — 0.5% - 1.2% x x x x x x x x x x x x x x
Muscle rigidity Muscle rigidity postmarketing x x x x x x x x x x x x x x x x x x
Mydriasis Mydriasis postmarketing, infrequent x x x x x x x x x x x x x x x x
Myocardial infarction Myocardial infarction postmarketing, rare x x x x x x x x x x x x x x x x
Acute coronary syndrome Myocardial infarction postmarketing, rare x x x x x x x x x x x x x x x x
Neuralgia Neuralgia postmarketing x x x x x x x x x x x x x x
Ovarian disorder Ovarian disorder rare x
Pallor Pallor rare x
Pancreatitis Pancreatitis postmarketing x x x x x x x x x x x x x x
Pancytopenia Pancytopenia postmarketing, rare x x x x x x x x x x x x x x x x x
Pelvic infection Pelvic infection rare x
Phlebitis Phlebitis postmarketing, rare x x x x x x x x x x x x x x x
Pneumonia Pneumonia postmarketing, rare x x x x x x x x x x x x x x
Prostatic disorder Prostatic disorder postmarketing, infrequent x x x x x x x x x x x x x x
Pulmonary embolism Pulmonary embolism postmarketing, rare x x x x x x x x x x x x x x x x
Rhabdomyolysis Rhabdomyolysis postmarketing x x x x x x x x x x x x x x x x x x
Salpingitis Salpingitis postmarketing x x x x x x x x x x x x x x
Sciatica Sciatica rare x
Serum sickness Serum sickness postmarketing x x x x x x x x x x x x x x x x x x
Salivary hypersecretion Salivary hypersecretion postmarketing, infrequent x x x x x x x x x x x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome postmarketing x x x x x x x x
Gastric ulcer Gastric ulcer postmarketing, rare x x x x x x x x x x x x x x x
Cerebrovascular accident Cerebrovascular accident postmarketing, infrequent x x x x x x x x x x x x x x
Suicide attempt Suicide attempt postmarketing x x x x x x x x x x x x
Shock Syncope postmarketing — 1.2% 0.5% x x x x x x x x x x x x x x x x x
Syncope Syncope postmarketing — 1.2% 0.5% x x x x x x x x x x x x x x x x x
Loss of consciousness Syncope postmarketing — 1.2% 0.5% x x x x x x x x x x x x x x x x x
Thrombocytopenia Thrombocytopenia postmarketing x x x x x x x x x x x x x x x x x x
Urinary incontinence Urinary incontinence postmarketing, rare x x x x x x x x x x x x x x x x
Urethral disorder Urinary tract disorder postmarketing x x x
Urinary tract disorder Urinary tract disorder postmarketing x x x
Vaginal inflammation Vaginal inflammation postmarketing x x x x x x x x x x x x x
Vaginal infection Vaginal inflammation postmarketing x x x x x x x x x x x x x
Vaginitis bacterial
Vasodilation procedure Vasodilation postmarketing, infrequent x x x x x x x x x x x x x x
Urinary retention Urinary retention postmarketing, 1.9% 2.2% x x x x x x x x x x x x x x
Skin odour abnormal Body odor rare x
Akinesia Akinesia postmarketing, 8% 8.6% x x x x x x x x x x x x x x
Oedema peripheral Oedema peripheral postmarketing, infrequent x x x x x x x x x x x x x
Hypokinesia Hypokinesia postmarketing x x x x x x x x x x x x x x
Atrioventricular block complete Atrioventricular block complete postmarketing x x x x x x x x x x x x x x x x x
Tongue disorder Tongue oedema postmarketing, rare x x x x x x x x x x x x x
Tongue oedema Tongue oedema postmarketing, rare x x x x x x x x x x x x x
Electroencephalogram abnormal Electroencephalogram abnormal postmarketing x x x x x x x x x x x x x x
Hepatocellular injury Hepatocellular injury postmarketing, infrequent x x x x x x x x x x x x x x x x x
Liver injury Hepatocellular injury postmarketing, infrequent x x x x x x x x x x