Fatigue

Definition: That state, following a period of mental or bodily activity, characterized by a lessened capacity for work and reduced efficiency or accomplishment, usually accompanied by a feeling of weariness, sleepiness, or irritability. (On-line Medical Dictionary)

Synonyms (terms occurring on more labels are shown first): fatigue, tiredness, lack of energy, fatigued, loss of energy, extreme fatigue, weariness, decreased energy

More information: PubMed search and possibly Wikipedia or Medpedia

Proteins predicted to cause Fatigue: CYP3A4, HTR1D, HTR1B (3 predictions in total) Show drugs for which this side effect directly occurs

Drugs with this side effect as MedDRA Preferred Term Clemastine Fatigue Dexchlorpheniramine Maleate Fatigue Mecamylamine Fatigue Pentostatin Fatigue: 29% - 55% Premetrexed Fatigue Tacrine Hydrochloride Capsules Fatigue Exhaustion: rare Thiotepa Fatigue Tolcapone Fatigue acebutolol (acebutolol hydrochloride) Fatigue: 11% acetaminophen Fatigue acetazolamide Fatigue acitretin Fatigue: postmarketing acyclovir Fatigue albuterol Fatigue: 1% alkeran Fatigue almotriptan Fatigue: infrequent alprazolam Fatigue: 9.2% - 48.6% altretamine Fatigue amantadine Fatigue amiloride Fatigue Fatigability amiodarone Fatigue amitriptyline Fatigue amlodipine Fatigue amoxapine Fatigue amprenavir Fatigue: 1% - 4% amsacrine Fatigue anastrozole Fatigue: postmarketing apomorphine Fatigue aripiprazole Fatigue: 2% - 17% Exhaustion: rare arsenic trioxide Fatigue asenapine Fatigue: 3% - 4% atenolol Fatigue: postmarketing, 0.6% - 26% atorvastatin calcium Fatigue: postmarketing azacitidine Fatigue azelastine Fatigue: 0% - 2.19% azithromycin Fatigue: postmarketing azopt Fatigue baclofen Fatigue: rare Lassitude Exhaustion balsalazide Fatigue: 2.32% - 4.41% benazepril Fatigue: 2.39% - 2.4% bendamustine Fatigue betaxolol Fatigue bexarotene Fatigue bicalutamide Fatigue bisoprolol fumarate Fatigue: postmarketing bortezomib Fatigue brimonidine Fatigue bromazepam Fatigue bromocriptine Fatigue: postmarketing Lassitude budesonide Fatigue bumetanide Fatigue buprenorphine Fatigue: 5% buserelin (buserelin acetate) Fatigue buspirone Fatigue: frequent busulfan Fatigue cabergoline Fatigue calcitonin salmon Fatigue candesartan cilexetil Fatigue capecitabine Fatigue: 4% - 46% captopril Fatigue carbamazepine Fatigue carbinoxamine Fatigue carvedilol Fatigue caspofungin (caspofungin acetate) Fatigue cefpodoxime Fatigue ceftibuten Fatigue ceftobiprole (ceftobiprole medocaril) Fatigue celecoxib Fatigue cephalexin Fatigue cetirizine Fatigue: 1.19% - 4.3% cevimeline hydrochloride Fatigue: 3.3% chlorambucil Fatigue ciclesonide Fatigue cilazapril (cilazapril monohydrate) Fatigue: postmarketing ciprofloxacin Fatigue: postmarketing cladribine Fatigue clindamycin Fatigue clobazam Fatigue: 3% - 5% clofarabine Fatigue clofazimine Fatigue clomiphene Fatigue clomipramine Fatigue: 35% - 39% clonazepam Fatigue: 6% - 9% Lassitude clonidine Fatigue: postmarketing, 4% - 16% clozapine Fatigue: 2% codeine Fatigue colchicine Fatigue: 1.35% - 3.85% colestipol Fatigue crixivan Fatigue cromolyn Fatigue cubicin Fatigue cyclobenzaprine Fatigue: postmarketing, frequent, 2% - 6% cyclophosphamide Fatigue cyclosporine Fatigue: rare, 3% - 12% cyproheptadine Fatigue cyproterone acetate Fatigue Lassitude cytarabine Fatigue: 25% - 46% dacarbazine Fatigue danazol Fatigue dantrolene Fatigue decitabine Fatigue: 46.5% deferasirox Fatigue degarelix Fatigue delavirdine mesylate Fatigue desflurane Fatigue: postmarketing desipramine Fatigue desloratadine Fatigue: 2.1% desmopressin acetate Fatigue detrol la Fatigue dextroamphetamine sulfate Fatigue Exhaustion: postmarketing diazepam Fatigue diclofenac Fatigue: postmarketing dicyclomine Fatigue diflunisal Fatigue dihydroergotamine Fatigue: 1% diltiazem Fatigue diphenhydramine Fatigue dipyridamole Fatigue: postmarketing disopyramide Fatigue disulfiram Fatigability docetaxel Fatigue dolasetron mesylate Fatigue: 2.55% - 5.73% donepezil Fatigue: 3% - 8% doxazosin Fatigue: postmarketing, 1.7% - 12% doxorubicin hydrochloride Fatigue dronabinol Fatigue: postmarketing edetic acid Fatigue efavirenz Fatigue: 2% emtricitabine Fatigue enalapril sodium Fatigue: 3% entacapone Fatigue: 6% entecavir Fatigue: 1% eplerenone Fatigue epoprostenol sodium Fatigue eprosartan (eprosartan mesylate) Fatigue: 2% esmolol hydrochloride Fatigue: postmarketing estradiol Fatigue estrogens, conjugated Fatigue ethacrynic acid Fatigue ethosuximide Fatigue ethotoin Fatigue etodolac Fatigue etonogestrel Fatigue: postmarketing etoposide Fatigue etravirine Fatigue exemestane Fatigue: 16.1% ezetimibe Fatigue: postmarketing famciclovir Fatigue: 0.6% - 4.8% famotidine Fatigue febuxostat Fatigue felbamate Fatigue fenofibrate Fatigue fenoprofen calcium Fatigue fentanyl Fatigue: postmarketing fexofenadine hydrochloride Fatigue: 0.2% - 2.8% flecainide Fatigue: 3% - 7.7% fluconazole Fatigue: postmarketing flucytosine Fatigue fludarabine Fatigue: postmarketing, 13% - 31% flumazenil Fatigue flunisolide Fatigue fluticasone propionate Fatigue fluvastatin sodium Fatigue fluvoxamine maleate Fatigue formoterol fumarate Fatigue fosamprenavir calcium Fatigue: 1% - 4% fosaprepitant dimeglumine Fatigue foscarnet sodium Fatigue fosinopril sodium Fatigue frovatriptan Fatigue fulvestrant Fatigue gabapentin Fatigue: 1.6% - 11% Lassitude: rare gadobenic acid Fatigue gadodiamide Fatigue gadofosveset Fatigue gadopentetate dimeglumine Fatigue galantamine Fatigue: 5% ganciclovir Fatigue gefitinib Fatigue gemcitabine Fatigue: postmarketing gemfibrozil Fatigue: postmarketing, 3.8% gemifloxacin mesylate Fatigue gliclazide Fatigue glutamine Fatigue: 0% - 13.3% goserelin Fatigue: 2% - 5% griseofulvin Fatigue guanfacine Fatigue: postmarketing, 0% - 14% halofantrine hydrochloride Fatigue histrelin Fatigue hydrochlorothiazide Fatigue hydrocortisone Fatigue hydromorphone Fatigue: postmarketing hydroxychloroquine Lassitude hydroxyurea Fatigue hyoscyamine Fatigue ibandronate sodium Fatigue: 1.1% - 2.8% ibutilide Fatigue ifosfamide Fatigue imatinib mesylate Fatigue: 1% - 74.9% imipramine Fatigue imiquimod Fatigue: 1% - 4.38% indapamide Fatigue indomethacin Fatigue insulin recombinant human Fatigue: postmarketing invanz Fatigue invirase Fatigue iodine Fatigue iodixanol Fatigue iopamidol Fatigue iopidine Fatigue ipratropium bromide Fatigue irbesartan Fatigue irinotecan Fatigue isoniazid Fatigue isosorbide-5-mononitrate Fatigue itraconazole Fatigue ivermectin Fatigue labetalol Fatigue: 5% lacosamide Fatigue: 7% - 15% lamivudine Fatigue: postmarketing, rare, 23% - 24% lamotrigine Fatigue: 5% - 8% lansoprazole Fatigue lenalidomide Fatigue letrozole Fatigue: 0.2% - 13% leucovorin Fatigue: 11.1% - 32.2% leuprolide acetate Fatigue levetiracetam Fatigue: 10% - 11% levocabastine Fatigue levocarnitine Fatigue levofloxacin Fatigue levonorgestrel Fatigue: postmarketing levothyroxine Fatigue linezolid Fatigue lisinopril Fatigue: 2.5% lithium cation Fatigue lodoxamide Fatigue loperamide hydrochloride Fatigue: postmarketing loratadine Fatigue lorazepam Fatigue losartan Fatigue: postmarketing, 10% - 14% lotronex Fatigue: infrequent lubiprostone Fatigue: 2% maraviroc Exhaustion maxaquin Fatigue meclizine Fatigue medroxyprogesterone acetate Fatigue: postmarketing mefloquine hydrochloride Fatigue: postmarketing meloxicam Fatigue: postmarketing memantine hydrochloride Fatigue: 2% mephenytoin Fatigue mesalamine Fatigue: postmarketing, 1% - 6.25% mesna Fatigue metformin Fatigue methamphetamine hydrochloride Fatigue methazolamide Fatigue methotrexate Fatigue methylnaltrexone bromide Fatigue methylphenidate hydrochloride Fatigue methysergide Fatigue metoclopramide Fatigue: postmarketing Lassitude: postmarketing metolazone Fatigue Lassitude metoprolol Fatigue: postmarketing metronidazole Fatigue metyrosine Fatigue mexiletine Fatigue micafungin sodium Fatigue mifepristone Fatigue miglustat Fatigue milnacipran Fatigue minocycline Fatigue misoprostol Fatigue: postmarketing mitomycin Fatigue mitoxantrone Fatigue: 8% - 39% modafinil Fatigue: 2% moexipril hydrochloride Fatigue mometasone furoate Fatigue moricizine Fatigue morphine Fatigue: postmarketing mycophenolic acid Fatigue: postmarketing nabilone Fatigue nabumetone Fatigue: postmarketing nadolol Fatigue naltrexone Fatigue: postmarketing Exhaustion: postmarketing naproxen Fatigue naratriptan Fatigue: 2% nardil Fatigue nateglinide Fatigue nebivolol Fatigue nedocromil sodium inhalation aerosol Fatigue nelarabine Fatigue: 2% - 50% nevirapine Fatigue: postmarketing nexavar Fatigue nicotine Fatigue nifedipine Fatigue nilotinib (nilotinib hydrochloride monohydrate) Fatigue nitrazepam Fatigue nortriptyline Fatigue olanzapine Fatigue: 2% - 14% olmesartan medoxomil Fatigue olopatadine Fatigue: 0.852% olsalazine Fatigue: 1.8% omeprazole Fatigue: postmarketing ondansetron Fatigue: 2% - 13.2% orlistat Fatigue: 3.1% oxaliplatin Fatigue oxcarbazepine Fatigue: 5% - 21% oxybutynin Fatigue: postmarketing oxycodone Fatigue paclitaxel Fatigue paliperidone Fatigue: 0% - 4% palonosetron Fatigue pamidronate disodium Fatigue: 0% - 40.3% pantoprazole Fatigue: postmarketing paricalcitol Fatigue penicillin g Prostration perindopril erbumine Fatigue: postmarketing phenoxybenzamine Fatigue pindolol Fatigue: 4% - 8% piperacillin (piperacillin sodium) Fatigue pirbuterol Fatigue: 0% pizotifen (pizotifen malate) Fatigue plavix Fatigue plerixafor Fatigue: 0% - 27% porfimer sodium Fatigue posaconazole Fatigue pralatrexate Fatigue: 1.8% - 36% pramipexole dihydrochloride monohydrate Fatigue: postmarketing, 3% - 9% pramlintide acetate Fatigue: 3.87% - 6.85% prasugrel Fatigue pravastatin sodium Fatigue: 1.9% - 8.4% prazosin Fatigue prednisone Fatigue pregabalin Fatigue: postmarketing, 5% - 8% prezista Fatigue prialt Fatigue primidone Fatigue procarbazine (procarbazine hydrochloride) Fatigue: postmarketing progesterone Fatigue: 1.73% - 8% promethazine Fatigue Lassitude propafenone hydrochloride Fatigue: 2% - 6% propofol Fatigue: postmarketing propranolol Fatigue: postmarketing, 4.49% - 7.06% Lassitude: postmarketing protriptyline Fatigue quetiapine (quetiapine fumarate) Fatigue: 3% - 14% quinapril Fatigue quinidine Fatigue: 7% raltegravir Fatigue ramelteon Fatigue: 3% ramipril Fatigue: 2% relpax Fatigue reyataz Fatigue ribavirin Fatigue: 17% - 68% rifampin Fatigue rifapentine Fatigue rifaximin Fatigue riluzole Fatigue rimantadine Fatigue: 0.9% - 1% risedronate sodium Fatigue risperidone Fatigue: postmarketing, frequent, 1% - 42% Lassitude Fatigability rivastigmine Fatigue rizatriptan (rizatriptan benzoate) Fatigue rofecoxib Fatigue romidepsin Fatigue ropinirole Fatigue: 8% - 11% rosiglitazone maleate Fatigue: 1.9% - 3.6% rotigotine Fatigue rufinamide Fatigue: 2% - 16% salmeterol xinafoate Fatigue secreflo Fatigue sensipar Fatigue singulair Fatigue: postmarketing sitagliptin (sitagliptin phosphate monohydrate) Fatigue sitaxsentan sodium Fatigue solifenacin succinate Fatigue sotalol hydrochloride Fatigue: 2% sprycel Fatigue: 1% - 24% stavudine Fatigue strattera Fatigue: 2% - 9% sulfisoxazole Fatigue Lassitude sulindac Fatigue sumatriptan (sumatriptan succinate) Fatigue: 1% - 3% sutent Fatigue tadalafil Fatigue tamoxifen citrate Fatigue: 1% - 4% tamsulosin Fatigue tapentadol Fatigue: 3% - 9% tarceva Fatigue: 4% - 52% tekturna Fatigue telbivudine Fatigue: 12.5% telithromycin Fatigue telmisartan Fatigue: postmarketing temazepam Fatigue: 4.8% temozolomide Fatigue terazosin Fatigue: 3.3% - 11.3% Lassitude: 3.3% - 11.3% terbinafine Fatigue: postmarketing testosterone Fatigue: postmarketing tetrabenazine Fatigue thalidomide Fatigue thiabendazole Fatigue thiothixene Fatigue tiagabine hydrochloride Fatigue tiludronic acid Fatigue timolol Fatigue: 1% - 5% tinidazole Fatigue tipranavir Fatigue: 5.6% tizanidine Fatigue: 41% - 78% tolazamide Fatigue topiramate Fatigue: postmarketing, frequent topotecan Fatigue: 0% - 29% toremifene Fatigue tracleer Fatigue tramadol Fatigue: 1.7% - 2.78% trandolapril Fatigue tranexamic acid Fatigue travoprost Fatigue trazodone Fatigue: 14.9% trelstar Fatigue: postmarketing treprostinil (treprostinil sodium) Fatigue tretinoin Fatigue: postmarketing triamcinolone Fatigue: postmarketing Lassitude triamterene Fatigue triazolam Fatigue trifluoperazine Fatigue trimetrexate glucuronate Fatigue: 2% troglitazone Fatigue trospium Fatigue trovafloxacin Fatigue trusopt Fatigue uroxatral Fatigue: 2.75% ursodiol Fatigue: 4.5% - 16.1% valacyclovir Fatigue valcyte Fatigue valdecoxib Fatigue valsartan Fatigue: 3% varenicline Fatigue venofer Fatigue: postmarketing verapamil Fatigue: 0.6% - 4.5% vigabatrin Fatigue: postmarketing, 23.1% - 39.5% vinorelbine Fatigue viread Fatigue warfarin Fatigue welchol Fatigue zalcitabine Fatigue zelnorm Fatigue: 1% ziagen Fatigue zidovudine Fatigue zinecard Fatigue: 48% - 61% zoledronic acid Fatigue: postmarketing, 2.1% - 39% zolpidem Fatigue: infrequent zonisamide Fatigue: 5% - 8%

Drugs with this indication bupropion dactinomycin citalopram doxepin fluoxetine isocarboxazid mirtazapine modafinil nefazodone tamiflu paroxetine pioglitazone (pioglitazone hydrochloride) selegiline sertraline venlafaxine octreotide (octreotide acetate) duloxetine desvenlafaxine enfuvirtide