Levetiracetam

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 44)
1 2 3 4 5 6 7 8 9 10
Somnolence def Somnolence def postmarketing, 0% - 23% 0% - 11% x x x x x x x x x x
Headache def Headache def 13% - 19% 13% - 15% x x x x x x x x x x
Asthenia def Asthenia def 0.683% - 15% 0% - 9% x x x x x x x x x x
Fatigue def 10% - 11% 5% - 8% x x x x x x
Nasopharyngitis def Nasopharyngitis def 7% - 15% 5% - 12% x x x x
Common cold def x
Vomiting def Vomiting def postmarketing, 13% - 15% 12% - 13% x x x x x x x x
Decreased appetite Anorexia def 2% - 13% 2% - 8% x x x x x x x x
Decreased appetite 8% 2%
Infection def Infection def 1% - 13% 1% - 8% x x x x x x x x x x
Rhinitis def Rhinitis def 2% - 13% 0% - 8% x x x x x x x x x
Common cold def x
Hostility def Hostility def 1% - 12% 1% - 6% x x x x x x x x x x
Irritability def Irritability def 0% - 12% 0% - 2% x x x x x x
Cough def Cough def 1% - 11% 1% - 7% x x x x x x x x
Cough increased 1% - 11% 1% - 7% x x x x x x
Fatigue def Fatigue def 10% - 11% 5% - 8% x x x x x x
Aggression def Aggression def postmarketing, 10% 5%
Nervousness def Nervousness def 0% - 10% 0% - 2% x x x x x x x x x x
Tension def Nervousness def 0% - 10% 0% - 2% x x x x x x x x x x
Pharyngitis def Pharyngitis def 0% - 10% 0% - 8% x x x x x x x x x x
Abdominal pain def Abdominal pain def 9% 8% x x x x x x x x
Gastrointestinal pain def Abdominal pain def 9% 8% x x x x x x x x
Dizziness def Dizziness def 1% - 9% 0% - 5% x x x x x x x x x x
Nasal congestion def Nasal congestion def 9% 2%
Pain def Pain def 0% - 9% 0% - 8% x x x x x x x x x
Abdominal pain upper Abdominal pain upper 9% 8%
Neck pain def Neck pain def 1% - 8% 1% - 2% x x x x x x x
Diarrhoea def Diarrhoea def 6% - 8% 5% - 7% x x x x x x x x
Gastrointestinal disorder def Gastrointestinal disorder def 8% 7% x x
Influenza def Influenza def 2% - 8% 1% - 4% x x x x x x x x x
Personality disorder def Personality disorder def 7% - 8% 7% x x x x x
Abnormal behaviour Abnormal behaviour 7% 4%
Oropharyngeal pain Pharyngolaryngeal pain def 7% 4%
Lethargy def Lethargy def 6% 2%
Agitation def Agitation def postmarketing, 1% - 6% 1% x x x x x
Hyperkinesia def x x x x x x
Mood swings Mood swings 0% - 6% 0% - 4% x x x x x x x x
Affect lability Mood swings 0% - 6% 0% - 4% x x x x x x x x
Affect lability 2% 1%
Nausea def Nausea def 5% 3% x x x x x x x x
Vertigo def Vertigo def 1% - 5% 1% - 3% x x x x x x x x x
Insomnia def Insomnia def 0% - 5% 0% - 3% x x x x x x x x x
Albuminuria def Albuminuria def 0% - 4% 0% x x x x x
Ecchymosis def Ecchymosis def 1% - 4% 1% x x x x x x x x x
Gastroenteritis def Gastroenteritis def 2% - 4% 0% - 2% x x x x x x x x
Convulsion def Convulsion def 2.99% - 3.42% 3.42% x x x x x x x x x
Anxiety def Anxiety def 1% - 3.33% 1% - 2% x x x x x x x x x
Ataxia def Ataxia def 1% - 3% 1% x x x x x x x x x x
Conjunctivitis def Conjunctivitis def 2% - 3% 0% - 2% x x x x x
Constipation def Constipation def 1% - 3% 1% x x x x x x x x
Amblyopia def Amblyopia def 0% - 2% 0% x x x x x x x x
Amnesia def Amnesia def 1% - 2% 1% x x x x x x x x x
Arthralgia def Arthralgia def 2% 0% x x x x x x x x
Musculoskeletal discomfort Arthralgia def 2% 0% x x x x x x x x
Myalgia def
Asthma def Asthma def 1% - 2% 1% x x x x x
Confusional state def Confusional state def 0% - 2% 0% x x x x x x x x
Feeling abnormal Confusional state def 0% - 2% 0% x x x x x x x x
Dehydration def Dehydration def 1% - 2% 1% x x x x x
Diplopia def Diplopia def 0% - 2% 0% - 1% x x x x x x x x
Ear pain def Ear pain def 0% - 2% 0% - 1% x x x x
Oedema def Oedema def 1% - 2% 1% x x x x x
Dermatitis def Rash def 0% - 2% 0% - 1.14% x x x x x x x x x
Rash def Rash def 0% - 2% 0% - 1.14% x x x x x x x x x
Paraesthesia def Paraesthesia def 1% - 2% 1% x x x x x x x x
Pruritus def Pruritus def 0% - 2% 0% x x x x x
Sinusitis def Sinusitis def 1% - 2% 1% x x x x x x x x x x
Viral infection def Viral infection def 1% - 2% 1% x x x x
Rash pustular def Vesiculobullous rash 0% - 2% 0% x x x x
Dermatitis bullous def Vesiculobullous rash 0% - 2% 0% x x x x
Hyperreflexia Hyperreflexia 1% - 2% 1% x x x x
Skin discolouration def Skin discolouration def 0% - 2% 0% x x x x
Urine abnormality Urine abnormality 1% - 2% 1% x x x x
Urine analysis abnormal Urine abnormality 1% - 2% 1% x x x x
Depressed mood def Depressed mood def 0% - 2% 0% x x x x x
Face oedema def Face oedema def 1% - 2% 1% x x x x
Sedation Sedation 2% 1%
Hypersomnia def Hypersomnia def 0% - 2% 0% x x x x x x
Alopecia def Alopecia def postmarketing x x x x x x x x
Mental disorder def Mental disorder def postmarketing x x x x x
Coma def Coma def postmarketing
Dyskinesia def Dyskinesia def postmarketing
Erythema multiforme def Erythema multiforme def postmarketing
Hepatitis def Hepatitis def postmarketing x x x x x x x
Leukopenia def Leukopenia def postmarketing x x x x x x x x x
Neutropenia def Neutropenia def postmarketing x x x x x x x x x
Pancreatitis def Pancreatitis def postmarketing x x x x x x x x
Pancytopenia def Pancytopenia def postmarketing x x x x x x x x x
Completed suicide Suicide def postmarketing x x x
Completed suicide postmarketing x x x
Suicide attempt def Suicide attempt def postmarketing x
Thrombocytopenia def Thrombocytopenia def postmarketing x x x x x x x x x
Erythema def Erythema def postmarketing
Weight decreased def Weight decreased def postmarketing x x x x x x x
Choreoathetosis Choreoathetosis postmarketing
Hepatic failure def Hepatic failure def postmarketing x x x x x
Hepatic function abnormal Hepatic function abnormal postmarketing x x x x x x x
Liver function test abnormal Liver function test abnormal postmarketing x x x x x x x
Respiratory depression Respiratory depression postmarketing
Pulmonary function test decreased Respiratory depression postmarketing
Renal impairment def Renal impairment def postmarketing
Suicidal ideation def Suicidal ideation def postmarketing x
Lymphadenopathy def Lymphadenopathy def postmarketing x
Altered state of consciousness Depressed level of consciousness def postmarketing
Depressed level of consciousness def Depressed level of consciousness def postmarketing
Suicidal behaviour Suicidal behaviour postmarketing x x x
Back pain def Back pain def x x x x x x x x
Bronchitis def Bronchitis def x x x x x x x x
Chest pain def Chest pain def x x x x x x x x
Connective tissue disorder def Connective tissue disorder def x x x x
Depersonalisation def Depersonalisation def
Drug abuse def Drug abuse def x x
Dysmenorrhoea def Dysmenorrhoea def
Dyspepsia def Dyspepsia def x x x x x x x x
Eczema def Eczema def
Grand mal convulsion def Grand mal convulsion def x x x x x x x x
Epistaxis def Epistaxis def x x x x x x
Eye disorder def Eye disorder def
Body temperature increased def Body temperature increased def x x x x x x x x
Gingivitis def Gingivitis def x x x x x x x x
Hallucination def Hallucination def
Hypersensitivity def Hypersensitivity def x x x x x x
Incontinence def Incontinence def x x x x x x
Mediastinal disorder def Mediastinal disorder def
Fungal infection def Fungal infection def x x x x x x x x
Nervous system disorder def Nervous system disorder def x x x x
Neurosis def Neurosis def
Ear infection def Otitis def x x x x x x x x
Otitis media def Otitis media def x x x x x x x x
Psychotic disorder def Psychotic disorder def
Status epilepticus def Status epilepticus def x x x x x x
Tooth disorder def Tooth disorder def x
Tremor def Tremor def x x x x x x x x
Ulcer def Ulcer def
Upper respiratory tract infection def Upper respiratory tract infection def x
Urinary incontinence def Urinary incontinence def x x x x x x
Urinary tract infection def Urinary tract infection def x x x x x x x x
Weight increased def Weight increased def x x x x x x x x
Apathy def Apathy def
Flat affect Apathy def
Stomatitis def Mouth ulceration def
Mouth ulceration def Mouth ulceration def
Drug level increased Drug level increased x x x x x x x x
Paranoia def Paranoid reaction
Myalgia def Myalgia def
Psychiatric symptom Psychiatric symptom
Disturbance in attention Disturbance in attention
Antisocial personality disorder def Antisocial behaviour def
Antisocial behaviour def Antisocial behaviour def
Asocial behaviour Antisocial behaviour def
Thinking abnormal Thinking abnormal x x x x x x x x x
Mental disability Thinking abnormal x x x x x x x x x
Memory impairment def Memory impairment def
Drug withdrawal convulsions Withdrawal seizures
Euphoric mood def Euphoric mood def
Major depression def Depressive type psychosis
Vision blurred def Vision blurred def
Hyperkinesia def Hyperkinesia def x x x x x x
Coordination abnormal Coordination abnormal
Gait disturbance def Gait disturbance def
Balance disorder Balance disorder
Aortic dissection def Dissecting aortic aneurysm, thoracic
Partial seizures def Partial seizures def x x x x x x x
Infestation Infestation NOS x x x x x x
Respiratory failure def Respiratory failure def
Indication Labels
Clonic convulsion def x x x x
Epilepsy def x x x x x x x x x x
Idiopathic generalised epilepsy x x x x
Juvenile myoclonic epilepsy def x x x x x x
Myoclonic epilepsy def x x x x x x x
Seizures def x x x x x x x x x
Tonic-clonic seizures def x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N03AX14

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. LEVETIRACETAM / PHL-LEVETIRACETAM : 29 side effects (Health Canada)
  2. LEVETIRACETAM : 44 side effects (FDA XML label)
  3. LEVETIRACETAM : 50 side effects (FDA XML label)
  4. levetiracetam / Keppra : 56 side effects (FDA MedWatch)
  5. LEVETIRACETAM / KEPPRA : 63 side effects (Drugs@FDA)
  6. LEVETIRACETAM : 79 side effects (FDA XML label)
  7. Levetiracetam : 92 side effects (FDA XML label)
  8. LEVETIRACETAM / KEPPRA : 94 side effects (Drugs@FDA)
  9. LEVETIRACETAM : 95 side effects (FDA XML label)
  10. levetiracetam : 95 side effects (FDA XML label)