Paraesthesia

Definition: Abnormal cutaneous sensations of tingling, numbness, pressure, cold, and warmth that an individual experiences without the presence of a stimulus. It results from functional disturbances of sensory neurons. Causes include peripheral vascular disease, peripheral neuropathy, and nerve damage.

Synonyms (terms occurring on more labels are shown first): paresthesia, paresthesias, paraesthesia, abnormal sensation, parasthesia, paraesthesias, parasthesias

More information: PubMed search and possibly Wikipedia or Medpedia

Proteins predicted to cause Paraesthesia: CYP2C9, HTR1B, HTR1D (6 predictions in total) Show drugs for which this side effect directly occurs

Drugs with this side effect as MedDRA Preferred Term Bromfenac Paraesthesia Clemastine Paraesthesia Dexchlorpheniramine Maleate Paraesthesia Imagent Paraesthesia Lindane Paraesthesia: postmarketing Mecamylamine Paraesthesia Pentostatin Paraesthesia Septocaine with epinephrine 1:100 Paraesthesia Tingling sensation Streptomycin Paraesthesia Tacrine Hydrochloride Capsules Paraesthesia: frequent Thiotepa Paraesthesia Tolcapone Paraesthesia acamprosate calcium Paraesthesia: 2% - 3% acebutolol (acebutolol hydrochloride) Paraesthesia acetazolamide Paraesthesia Tingling sensation acyclovir Paraesthesia adenosine Tingling sensation albuterol Paraesthesia alcohol Paraesthesia alkeran Tingling sensation allopurinol Paraesthesia Tingling sensation almotriptan Paraesthesia amantadine Paraesthesia: postmarketing amikacin Paraesthesia amiloride Paraesthesia amiodarone Paraesthesia amitriptyline Paraesthesia Tingling sensation amlodipine Paraesthesia amoxapine Paraesthesia Tingling sensation amphotericin b Paraesthesia amprenavir Paraesthesia: postmarketing amsacrine Paraesthesia anagrelide hydrochloride Paraesthesia: 5.9% anastrozole Paraesthesia: postmarketing, 3.56% - 6.1% aripiprazole Paraesthesia: infrequent arsenic trioxide Paraesthesia asenapine Paraesthesia atenolol Paraesthesia atorvastatin calcium Paraesthesia azelaic acid Tingling sensation: 3.72% - 15.5% azelastine Paraesthesia: postmarketing azilect Paraesthesia: infrequent, 2% azithromycin Paraesthesia: postmarketing aztreonam Paraesthesia baclofen Paraesthesia: 0.7% - 6.7% Tingling sensation baycol Paraesthesia benazepril Paraesthesia: postmarketing betaxolol Paraesthesia bexarotene Paraesthesia: 6% bicalutamide Paraesthesia bisoprolol fumarate Paraesthesia: postmarketing Tingling sensation bleomycin sulfate Paraesthesia bortezomib Paraesthesia: 0% - 27.5% bromocriptine Paraesthesia Tingling sensation budesonide Paraesthesia bupivacaine Paraesthesia buprenorphine Paraesthesia: 2% bupropion Paraesthesia: postmarketing, 1% - 2% buserelin (buserelin acetate) Paraesthesia butorphanol tartrate Paraesthesia cabergoline Paraesthesia calcipotriene Tingling sensation calcitonin salmon Paraesthesia Tingling sensation calcium Tingling sensation candesartan cilexetil Paraesthesia capecitabine Paraesthesia: 1% - 21% Tingling sensation capsaicin Paraesthesia captopril Paraesthesia carbamazepine Paraesthesia carbinoxamine Paraesthesia carboplatin Paraesthesia carboprost (carboprost tromethamine) Paraesthesia carmustine Paraesthesia: 5.83% carvedilol Paraesthesia caspofungin (caspofungin acetate) Paraesthesia cefaclor Paraesthesia: postmarketing cefepime Paraesthesia cefpodoxime Paraesthesia ceftazidime Paraesthesia ceftibuten Paraesthesia ceftizoxime Paraesthesia ceftriaxone Paraesthesia: postmarketing celecoxib Paraesthesia cetirizine Paraesthesia: postmarketing cevimeline hydrochloride Paraesthesia chlorhexidine Paraesthesia: postmarketing chlorothiazide Paraesthesia chlorthalidone Paraesthesia cidofovir anhydrous Paraesthesia cilazapril (cilazapril monohydrate) Paraesthesia cinoxacin Tingling sensation ciprofloxacin Paraesthesia: postmarketing citalopram Paraesthesia: frequent, 2% clobetasol Tingling sensation clomiphene Paraesthesia: postmarketing clomipramine Paraesthesia: 2% - 9% clonidine Paraesthesia: postmarketing clozapine Paraesthesia: postmarketing colistin Paraesthesia Tingling sensation crixivan Paraesthesia: postmarketing cromolyn Paraesthesia cubicin Paraesthesia cyanocobalamin Paraesthesia cyclobenzaprine Paraesthesia: postmarketing, frequent Tingling sensation cycloserine Paraesthesia cyclosporine Paraesthesia: postmarketing, 1% - 11% Tingling sensation cyproheptadine Paraesthesia cytarabine Paraesthesia dacarbazine Paraesthesia Facial paresthesia danazol Paraesthesia deferoxamine mesylate Paraesthesia: rare delavirdine mesylate Paraesthesia Tingling sensation denavir Paraesthesia: postmarketing desipramine Paraesthesia Tingling sensation desvenlafaxine Paraesthesia: 1% - 3% dexamethasone Paraesthesia Tingling sensation dexpanthenol Tingling sensation dextrose Paraesthesia diatrizoic acid Paraesthesia diazoxide Paraesthesia diclofenac Paraesthesia: postmarketing, 1% - 1.05% dicyclomine Tingling sensation: postmarketing didanosine Tingling sensation diflunisal Paraesthesia dihydroergotamine Paraesthesia: 2% diltiazem Paraesthesia: postmarketing dimercaprol Tingling sensation dinoprostone Paraesthesia diphenhydramine Paraesthesia dipyridamole Paraesthesia: postmarketing disopyramide Paraesthesia Tingling sensation docetaxel Paraesthesia dofetilide Paraesthesia dolasetron mesylate Paraesthesia donepezil Paraesthesia: frequent doxapram hydrochloride Paraesthesia doxazosin Paraesthesia: postmarketing, 1% doxepin Paraesthesia doxercalciferol Paraesthesia doxorubicin hydrochloride Paraesthesia duloxetine Paraesthesia: postmarketing, frequent, 2% - 4% edetic acid Paraesthesia Tingling sensation efavirenz Paraesthesia: postmarketing eflornithine hydrochloride Tingling skin Tingling sensation emtricitabine Paraesthesia enalapril sodium Paraesthesia enfuvirtide Paraesthesia epoprostenol sodium Paraesthesia eprosartan (eprosartan mesylate) Paraesthesia ergotamine Paraesthesia esmolol hydrochloride Paraesthesia: postmarketing estazolam Paraesthesia: rare, infrequent estradiol Paraesthesia estrogens, conjugated Paraesthesia: 5.9% - 7.5% eszopiclone Paraesthesia: infrequent etidronate disodium Paraesthesia: postmarketing etodolac Paraesthesia: postmarketing etonogestrel Paraesthesia: postmarketing etoposide Tingling sensation etravirine Paraesthesia exemestane Paraesthesia ezetimibe Paraesthesia: postmarketing famciclovir Paraesthesia: 0% - 0.9% famotidine Paraesthesia febuxostat Paraesthesia felbamate Paraesthesia felodipine Paraesthesia fenofibrate Paraesthesia: postmarketing fentanyl Paraesthesia: postmarketing flecainide Paraesthesia fluconazole Paraesthesia: postmarketing flucytosine Paraesthesia fludarabine Paraesthesia: postmarketing flumazenil Paraesthesia fluocinolone acetonide Paraesthesia fluorouracil Tingling sensation fluoxymesterone Paraesthesia Paresthesia generalized flurbiprofen Paraesthesia: postmarketing fluvastatin sodium Paraesthesia: postmarketing fluvoxamine maleate Paraesthesia: infrequent, 1% - 3% formoterol fumarate Paraesthesia fosamprenavir calcium Paraesthesia: postmarketing foscarnet sodium Paraesthesia fosfomycin tromethamine Paraesthesia fosinopril sodium Paraesthesia fosphenytoin sodium Paraesthesia Tingling sensation frovatriptan Paraesthesia Tingling sensation fulvestrant Paraesthesia: postmarketing furosemide Paraesthesia gabapentin Paraesthesia: infrequent, frequent gadobenic acid Paraesthesia: 0.8% gadobutrol Paraesthesia gadodiamide Paraesthesia: postmarketing gadofosveset Paraesthesia gadopentetate dimeglumine Paraesthesia gadoteridol Paraesthesia Tingling sensation gadoversetamide Paraesthesia: 2.22% galantamine Paraesthesia: infrequent ganciclovir Paraesthesia gatifloxacin Paraesthesia: postmarketing gemcitabine Paraesthesia: postmarketing gemfibrozil Paraesthesia gentamicin Tingling skin Tingling sensation geodon Paraesthesia: rare, frequent, 0% - 2% glatiramer acetate Paraesthesia: postmarketing, infrequent gliclazide Paraesthesia glimepiride Paraesthesia: postmarketing glipizide Paraesthesia goserelin Paraesthesia griseofulvin Paraesthesia guanfacine Paraesthesia: postmarketing halobetasol Paraesthesia halofantrine hydrochloride Paraesthesia histrelin Paraesthesia Paresthesia lower limb Tingling sensation hydralazine Paraesthesia Tingling sensation hydrochlorothiazide Paraesthesia hydrocortisone Paraesthesia Tingling sensation hydromorphone Paraesthesia ibuprofen Paraesthesia: postmarketing imatinib mesylate Paraesthesia: rare, infrequent imipramine Paraesthesia Tingling sensation imiquimod Tingling sensation: postmarketing indapamide Paraesthesia Tingling sensation indomethacin Paraesthesia insulin recombinant human Paraesthesia Tingling sensation invanz Paraesthesia invirase Paraesthesia iodine Paraesthesia iodixanol Paraesthesia iopamidol Paraesthesia Tingling sensation iopidine Paraesthesia iopromide Paraesthesia iothalamic acid Paraesthesia ioversol Paraesthesia ioxilan Paraesthesia ipratropium bromide Paraesthesia irbesartan Paraesthesia irinotecan Paraesthesia: postmarketing isocarboxazid Paraesthesia: 0% - 2% isoniazid Paraesthesia isosorbide-5-mononitrate Paraesthesia itraconazole Paraesthesia ivermectin Paraesthesia ketoconazole Paraesthesia ketoprofen Paraesthesia: postmarketing ketorolac Paraesthesia ketotifen (ketotifen fumarate) Tingling sensation labetalol Paraesthesia: 1% Tingling sensation lacosamide Paraesthesia lamivudine Paraesthesia: postmarketing, rare lamotrigine Paraesthesia: frequent lansoprazole Paraesthesia: postmarketing leflunomide Paraesthesia: 1% - 4% lenalidomide Paraesthesia letrozole Paraesthesia: postmarketing leuprolide acetate Paraesthesia Paresthesia lower limb levetiracetam Paraesthesia: 1% - 2% levitra Paraesthesia levobunolol Paraesthesia levocarnitine Paraesthesia levofloxacin Paraesthesia: 1% lidocaine Paraesthesia: postmarketing linezolid Paraesthesia lisinopril Paraesthesia: 0.8% losartan Paraesthesia lovastatin Paraesthesia: postmarketing loxapine Paraesthesia lubiprostone Paraesthesia maraviroc Paraesthesia maxaquin Paraesthesia medroxyprogesterone acetate Paraesthesia: postmarketing mefenamic acid Paraesthesia mefloquine hydrochloride Paraesthesia: postmarketing megestrol Paraesthesia meloxicam Paraesthesia: postmarketing memantine hydrochloride Paraesthesia: infrequent mepivacaine Paraesthesia meprobamate Paraesthesia meridia Paraesthesia: 2% meropenem Paraesthesia mesalamine Paraesthesia: postmarketing metformin Paraesthesia methazolamide Paraesthesia Tingling sensation methimazole Paraesthesia methyldopa Paraesthesia methylphenidate hydrochloride Paraesthesia: postmarketing, 1.2% methylprednisolone Paraesthesia Tingling sensation methyltestosterone Paraesthesia Paresthesia generalized methysergide Paraesthesia metolazone Paraesthesia metoprolol Paraesthesia: postmarketing metronidazole Paraesthesia: postmarketing Paresthesia of limbs Tingling sensation mexiletine Paraesthesia midazolam Paraesthesia midodrine Paraesthesia: 18.3% miglustat Paraesthesia Tingling sensation milnacipran Paraesthesia minocycline Paraesthesia minoxidil Tingling sensation mirtazapine Paraesthesia: postmarketing, frequent mitoxantrone Paraesthesia modafinil Paraesthesia: 1% mometasone furoate Paraesthesia Tingling sensation moricizine Paraesthesia morphine Paraesthesia moxifloxacin hydrochloride Paraesthesia myambutol Tingling sensation mycophenolic acid Paraesthesia: 18% - 20.8% nabilone Paraesthesia: postmarketing nabumetone Paraesthesia: postmarketing nadolol Paraesthesia nalbuphine Tingling sensation nalidixic acid Paraesthesia naloxone Paraesthesia naltrexone Paraesthesia naproxen Paraesthesia: postmarketing naratriptan Paraesthesia: 1% - 2% nardil Paraesthesia natrecor Paraesthesia nebivolol Paraesthesia nefazodone Paraesthesia nelarabine Paraesthesia: 0% - 15% nelfinavir mesylate Paraesthesia nevirapine Paraesthesia: postmarketing niacin Paraesthesia: postmarketing Tingling sensation nicardipine Paraesthesia nicotine Paraesthesia Tingling sensation nifedipine Paraesthesia nilotinib (nilotinib hydrochloride monohydrate) Paraesthesia nilutamide Paraesthesia nisoldipine Paraesthesia nitroglycerin Paraesthesia norfloxacin Tingling sensation nortriptyline Paraesthesia Tingling sensation octreotide (octreotide acetate) Tingling sensation olanzapine Paraesthesia: rare, frequent olsalazine Paraesthesia: postmarketing omeprazole Paraesthesia: postmarketing ondansetron Paraesthesia: 1.65% orlistat Paraesthesia oxaliplatin Paraesthesia oxaprozin Paraesthesia oxiconazole Tingling sensation oxybutynin Paraesthesia oxycodone Paraesthesia: postmarketing paclitaxel Paraesthesia Tingling sensation: postmarketing palonosetron Paraesthesia pamidronate disodium Paraesthesia: rare pantoprazole Paraesthesia: postmarketing paricalcitol Paraesthesia pentazocine Paraesthesia pentosan polysulfate sodium Paraesthesia pergolide mesylate Paraesthesia: frequent, 1.6% - 3.2% perindopril erbumine Paraesthesia permethrin Tingling sensation phentolamine Paraesthesia phenytoin Paraesthesia Tingling sensation pilocarpine Paraesthesia pindolol Paraesthesia: 1% - 3% piroxicam Paraesthesia plavix Paraesthesia plerixafor Paraesthesia podofilox Tingling sensation polidocanol Paraesthesia: postmarketing polymyxin b Paraesthesia polythiazide Paraesthesia posaconazole Paraesthesia pramipexole dihydrochloride monohydrate Paraesthesia pravastatin sodium Paraesthesia: postmarketing, 3.2% prazosin Paraesthesia prednicarbate Paraesthesia prednisolone Paraesthesia prednisone Paraesthesia pregabalin Paraesthesia: postmarketing, infrequent, frequent prezista Paraesthesia prialt Paraesthesia prilocaine Paraesthesia procarbazine (procarbazine hydrochloride) Paraesthesia: postmarketing progesterone Paraesthesia: postmarketing propafenone hydrochloride Paraesthesia: postmarketing propofol Paraesthesia: postmarketing propranolol Paraesthesia: postmarketing Paraesthesia hand: postmarketing propylthiouracil Paraesthesia protriptyline Paraesthesia Tingling sensation pyridostigmine Tingling sensation pyridoxine Paraesthesia quetiapine (quetiapine fumarate) Paraesthesia: 3% quinapril Paraesthesia rabeprazole sodium Paraesthesia ramipril Paraesthesia: postmarketing ranolazine Paraesthesia: postmarketing relpax Paraesthesia: 3% - 4% Tingling sensation repaglinide Paraesthesia retapamulin Paraesthesia rifabutin Paraesthesia riluzole Paraesthesia risedronate sodium Paraesthesia risperidone Paraesthesia: infrequent ritonavir Paraesthesia rivastigmine Paraesthesia: frequent rizatriptan (rizatriptan benzoate) Paraesthesia Tingling sensation rofecoxib Paraesthesia ropinirole Paraesthesia: 3% - 5% ropivacaine hydrochloride Paraesthesia rosuvastatin calcium Paraesthesia rotigotine Paraesthesia salmeterol xinafoate Paraesthesia secreflo Tingling sensation selegiline Paraesthesia: infrequent, frequent sensipar Paraesthesia sildenafil Paraesthesia simvastatin Paraesthesia: postmarketing singulair Paraesthesia: postmarketing sirolimus Paraesthesia sitaxsentan sodium Paraesthesia sotalol hydrochloride Paraesthesia: 1% stavudine Paraesthesia Tingling sensation strattera Paraesthesia: postmarketing, 1% - 3% sulfisoxazole Paraesthesia sulindac Paraesthesia sumatriptan (sumatriptan succinate) Paraesthesia: 2% - 5% Tingling sensation: 3% - 14% synarel Paraesthesia: postmarketing tacrolimus Paraesthesia: 1% - 40% Tingling skin: 1% - 2% Tingling sensation: 1% - 2% tadalafil Paraesthesia tamoxifen citrate Paraesthesia tamsulosin Paraesthesia tapentadol Paraesthesia telithromycin Paraesthesia telmisartan Paraesthesia temozolomide Paraesthesia terazosin Paraesthesia: 0.2% - 2.9% terbinafine Paraesthesia: postmarketing terbutaline Paraesthesia testosterone Paraesthesia Paresthesia generalized thalidomide Paraesthesia: 5.56% - 15.6% thiabendazole Paraesthesia tiagabine hydrochloride Paraesthesia: infrequent, 4% tiludronic acid Paraesthesia timolol Paraesthesia: 0.6% tinidazole Paraesthesia tiotropium Paraesthesia tizanidine Paraesthesia: frequent topiramate Paraesthesia: postmarketing, 3% - 40% topotecan Paraesthesia tracleer Paraesthesia tramadol Paraesthesia: postmarketing trandolapril Paraesthesia trazodone Paraesthesia: postmarketing Tingling sensation trelstar Paraesthesia: postmarketing Paresthesia lower limb: postmarketing treprostinil (treprostinil sodium) Paraesthesia tretinoin Paraesthesia: postmarketing Tingling sensation triamcinolone Paraesthesia triazolam Paraesthesia trovafloxacin Paraesthesia trusopt Paraesthesia: postmarketing ultiva Paraesthesia: 0.881% ursodiol Paraesthesia valacyclovir Paraesthesia valcyte Paraesthesia: 8% valdecoxib Paraesthesia valproic acid Paraesthesia: postmarketing, 0.9% valsartan Paraesthesia venofer Paraesthesia: postmarketing verapamil Paraesthesia: postmarketing, 1% vigabatrin Paraesthesia: 2.33% - 6.72% vincristine Paraesthesia Tingling sensation vinorelbine Paraesthesia: 0% - 25% viread Paraesthesia voriconazole Paraesthesia: postmarketing warfarin Paraesthesia zaleplon Paraesthesia: infrequent, frequent ziagen Paraesthesia zidovudine Paraesthesia: postmarketing zoledronic acid Paraesthesia: 2% - 15% zolmitriptan Paraesthesia: 5% - 10% Tingling sensation zolpidem Paraesthesia: infrequent zonisamide Paraesthesia: 1% - 4%

Drugs with this indication alprazolam buspirone clonazepam fluoxetine paroxetine sertraline venlafaxine octreotide (octreotide acetate)