Chlorothiazide

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Agranulocytosis def Agranulocytosis def x x x x x x x
Alopecia def Alopecia def x x x x x x
Anaphylactic shock def Anaphylactic shock def x x x x x x x
Anaemia def Anaemia def x x x x x x x
Aplastic anaemia def Aplastic anaemia def x x x x x x x
Haemolytic anaemia def Haemolytic anaemia def x x x x x x x
Decreased appetite Anorexia def x x x x x x x
Constipation def Constipation def x x x x x x x
Dermatitis def Dermatitis def x x x x x x
Rash def x x x x x x x
Dermatitis exfoliative def Dermatitis exfoliative def x x x x x x
Diarrhoea def Diarrhoea def x x x x x x x
Dizziness def Dizziness def x x x x x x x
Toxic epidermal necrolysis def Toxic epidermal necrolysis def x x x x x x
Necrolysis epidermal x x x x x x
Erythema multiforme def Erythema multiforme def x x x x x x
Rash def Rash def x x x x x x x
Body temperature increased def Body temperature increased def x x x x x x x
Glycosuria def Glycosuria def x x x x x x x
Headache def Headache def x x x x x x x
Haematuria def Haematuria def x x
Hyperglycaemia def Hyperglycaemia def x x x x x x x
Hypersensitivity def Hypersensitivity def x x x x x x x
Jaundice cholestatic def Jaundice cholestatic def x x x x x x x
Leukopenia def Leukopenia def x x x x x x x
Muscle spasms def Cramp muscle def x x x x x x x
Muscle spasms def x x x x x x x
Nausea def Nausea def x x x x x x x
Nephritis def Nephritis def x x x x x x x
Tubulointerstitial nephritis Nephritis interstitial def x x x x x x x
Pancreatitis def Pancreatitis def x x x x x x x
Paraesthesia def Paraesthesia def x x x x x x x
Pneumonia def Pneumonia def x x x x x x x
Pulmonary oedema def Pulmonary oedema def x x x x x x x
Purpura def Purpura def x x x x x x x
Vascular purpura Purpura def x x x x x x x
Sialoadenitis def Sialoadenitis def x x x x x x x
Erythema def Erythema def x x x x x x
Urticaria def Urticaria def x x x x x x x
Vasculitis def Vasculitis def x x x x x x x
Vertigo def Vertigo def x x x x x x x
Vomiting def Vomiting def x x x x x x x
Agitation def Agitation def x x x x x x x
Xanthopsia Xanthopsia x x x x x x
Erectile dysfunction def Erectile dysfunction def x x x x x
Cutaneous vasculitis Cutaneous vasculitis x x x x x x x
Vision blurred def Vision blurred def x x x x x x
Photosensitivity reaction def Photosensitivity def x x x x x x x
Abdominal discomfort Gastric irritation x x x x x x x
Social avoidant behaviour Withdrawn x x x x x
Respiratory distress def Respiratory distress def x x x x x x x
Vasculitis necrotising def Angiitis necrotising def x x x x x x
Blood uric acid increased Hyperuricaemia def x x x x x x x
Hyperuricaemia def Hyperuricaemia def x x x x x x x
Asthenia def Weakness def x x x x x x x
Indication Labels
Adverse reaction def x
Attention deficit disorder of childhood x
Breast feeding def x
Calcium metabolism disorder def x x
Carcinogenicity x
Cardiac failure def x x x x x x x
Cardiac failure congestive def x x x x x x x
Cardiovascular disorder def x x x x x
Discomfort def x x x x x
Drug interaction def x
Elderly def x
Electrolyte depletion x
Electrolyte imbalance def x
Fertilization def x
Fluid overload def x x x x x
Function kidney decreased x
Generalised oedema x x x x x
Glomerulonephritis def x x x x x x x
Glomerulonephritis acute x x x x x
Gravid x x x x x
Gravitational oedema x x x x x
Hepatic cirrhosis def x x x x x x x
Hypercalcaemia def x x
Hyperparathyroidism def x x
Hypertension def x x x
Hypokalaemia def x
Hypomagnesaemia def x
Hypotension def x
Hypotonia def x
Jaundice def x
Jaundice neonatal def x
Nephrotic syndrome def x x x x x x x
Normal pregnancy def x x x x x
Oedema def x x x x x x x
Orthostatic hypotension def x
Parathyroid disorder def x x
Pre-eclampsia def x x x x x
Renal failure def x x x x x x x
Renal failure chronic def x x x x x x x
Renal impairment def x
Retinitis pigmentosa def x
Salmonellosis def x
Teratogenicity def x
Thrombocytopenia def x
Toxemia def x x x x x
Uterine disorder def x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: C03AA04

Legend

Color scheme: standard – alternative

100%    
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frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. chlorothiazide / Diuril : 40 side effects (FDA MedWatch)
  2. chlorothiazide sodium / Diuril : 49 side effects (FDA MedWatch)
  3. chlorothiazide : 50 side effects (FDA XML label)
  4. CHLOROTHIAZIDE : 51 side effects (FDA XML label)
  5. chlorothiazide : 51 side effects (FDA XML label)
  6. CHLOROTHIAZIDE : 52 side effects (FDA XML label)
  7. CHLOROTHIAZIDE : 52 side effects (FDA XML label)