Search results :

Letrozole

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L02BG04

Side effects

Options: Hide MedDRA Preferred Terms ,   display all 29 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Flushing Flushing 0.117% - 49.7% 0% - 43.3% x x x x x x x x x x x x x x
Musculoskeletal disorder Musculoskeletal disorder 2.77% - 38.2% 1.94% - 32.5% x x x x x x x x x x x x x x
Nervous system disorder Nervous system disorder 2.54% - 33.7% 2.25% - 31.8% x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder 1.68% - 28.3% 1.63% - 28.4% x x x x x x x x x x x x x x x x x x
Skin disorder Skin disorder 0.663% - 32.4% 0.622% - 30.6% x x x x x x x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue x x x
Menopausal symptoms Hot flush very common, 3% - 38% x x x x x x x x x x x x x x x x x x x x
Hot flush Hot flush very common, 3% - 38% x x x x x x x x x x x x x x x x x x x x
Night sweats Night sweats 10.7% - 17.4% x x x x x x x x x x x x x
Hyperhidrosis Sweating 1-22% x
Sweating increased common, 0.039% - 24.2% 0% - 22.4% x x x x x x x x x x x x x x x x x x x
Nausea Nausea common, 0.117% - 17% 0.389% - 8.24% x x x x x x x x x x x x x x x x x x x x
Metabolic disorder Metabolic disorder 0.936% - 21.5% 1.24% - 20.9% x x x x x x x x x x x x x x
Multiple fractures Fracture common, 4% - 13.8% x x x x x x x x x x x x x x x x x x x x
Fracture Fracture common, 4% - 13.8% x x x x x x x x x x x x x x x x x x x x
Arthralgia Arthralgia very common, 0.975% - 25.2% 0.777% - 18.1% x x x x x x x x x x x x x x x x x x x x
Musculoskeletal discomfort Arthralgia very common, 0.975% - 25.2% 0.777% - 18.1% x x x x x x x x x x x x x x x x x x x x
Myalgia common, 0.312% - 12-21% 0.233% - 4.74% x x x x x x x x x x x x x x x x x x
Asthenia Fatigue common, 0.151% - 11-30% x x x x x x x x x x x x x x x x x x x x
Asthenia 0.151% - 33.6% 0.272% - 32.1% x x x x x x x x x x x x x x x x x x
Fatigue Fatigue common, 0.151% - 11-30% x x x x x x x x x x x x x x x x x x x x
Dyspnoea Dyspnoea uncommon, 0.819% - 18% 0.7% - 5.32% x x x x x x x x x x x x x x x x x x x x
Headache Headache common, 0.204% - 20.1% 0.661% - 19.7% x x x x x x x x x x x x x x x x x x x x
Lymphoedema Lymphoedema 7% x x x x x x x x x x x x x x x x
Mental disorder Mental disorder 0.819% - 12.5% 0.622% - 10.7% x x x x x x x x x x x x x x x x x x
Pain Pain 5% - 7% x x x x x x x x x x x x x x x x x
Abdominal pain Abdominal pain uncommon, 5% - 9% x x x x x x x x x x x x x x x x x x x x
Gastrointestinal pain Abdominal pain uncommon, 5% - 9% x x x x x x x x x x x x x x x x x x x x
Chest pain Chest pain 3% - 9% x x x x x x x x x x x x x x x x x
Musculoskeletal chest pain Chest wall pain 6% x x x x x x x x x x x x x x x
Constipation Constipation common, 0.0251% - 11.3% 0.0777% - 11.8% x x x x x x x x x x x x x x x x x x x x
Cough Cough uncommon, 5% - 13% x x x x x x x x x x x x x x x x x x x x
Hypertension Hypertension uncommon, 4% - 8% x x x x x x x x x x x x x x x x x x x
Vulvovaginal dryness Vulvovaginal dryness 0% - 5.35% 0% - 4.94% x x x x x x x x x x x x x x
Vaginal dryness uncommon x x x
Back pain Back pain 0.176% - 70.5% 0.272% - 4.35% x x x x x x x x x x x x x x x x
Infection Infection 1.56% - 6.48% 1.28% - 6.34% x x x x x x x x x x x x x x x x x x x
Dyspepsia Dyspepsia common, 3% - 6% x x x x x x x x x x x x x x x x x x x x
Dermatitis Rash common, 3% - 12% x x x x x x x x x x x x x x x x x x x x
Rash Rash common, 3% - 12% x x x x x x x x x x x x x x x x x x x x
Influenza Influenza 4% - 6% x x x x x x x x x x x x x x x x
Viral infection Viral infection 3% - 6% x x x x x x x x x x x x x x x x
Vomiting Vomiting common, 0.0755% - 9% x x x x x x x x x x x x x x x x x x x x
Weight decreased Weight decreased uncommon, 0.125% - 7% x x x x x x x x x x x x x x x x x x x
Oedema peripheral Oedema peripheral common, 3% - 9-17% x x x x x x x x x x x x x x x x x x x x
Leg edema x x x x x x x x x x
Edema of lower extremities x
Myalgia Myalgia common, 0.312% - 12-21% 0.233% - 4.74% x x x x x x x x x x x x x x x x x x
Increased appetite Increased appetite common, 1% x x x x x x x x x x x x x x x x
Infestation Infestation NOS 1.56% - 6.48% 1.28% - 6.34% x x x x x x x x x x x x x x x x x x x
Diarrhoea Diarrhoea common, 0.468% - 8% 0.311% - 5.56% x x x x x x x x x x x x x x x x x x x x
Bone pain Bone pain common, 0.1% - 22% x x x x x x x x x x x x x x x x x x x
Decreased appetite Anorexia common, 0.0251% - 6% x x x x x x x x x x x x x x x x x x x x
Decreased appetite x
Insomnia Insomnia uncommon, 0.078% - 7% 0.0777% - 4.66% x x x x x x x x x x x x x x x x x x x x
Arthritis Arthritis uncommon, 0.39% - 25.2% 0.194% - 4.82% x x x x x x x x x x x x x x x x x x
Alopecia Alopecia common, 2.09% - 3.43% x x x x x x x x x x x x x x x x x x x x
Pain in extremity Pain in extremity 0.1% - 10% x x x x x x x x x x x x x x x x
Leg pain x x x x x x x x x x
Pain in arm x x x x x x x x x x
Neoplasm malignant Neoplasm malignant 1.33% - 4.86% x x x x x x x x x x x x x x
Lethargy Lethargy 0.151% - 10.2% x x x x x x x x x x x x x
Malaise Malaise 0.151% - 10.2% x x x x x x x x x x x x x x x x
Discomfort Malaise 0.151% - 10.2% x x x x x x x x x x x x x x x x
Feeling abnormal Malaise 0.151% - 10.2% x x x x x x x x x x x x x x x x
Ill-defined disorder Malaise 0.151% - 10.2% x x x x x x x x x x x x x x x x
Osteopenia Osteopenia 0.0502% - 3.55% x x x x x x x x x x
Dizziness Dizziness common, 0.0252% - 14.2% 0.233% - 13.3% x x x x x x x x x x x x x x x x x x x x
Lightheadedness 0.0252% - 3.43% x x x x x x x x x x x x x
Hypercholesterolaemia Hypercholesterolaemia common, 0% - 52.3% 0.194% - 15.5% x x x x x x x x x x x x x x x x x x x x
Urinary tract infection Urinary tract infection uncommon, 3% - 6% x x x x x x x x x x x x x x x x x x
Weight increased Weight increased common, 0.679% - 15.4% x x x x x x x x x x x x x x x x x x x x
Somnolence Somnolence uncommon, 2% - 9% x x x x x x x x x x x x x x x x x x x x
Depression Depression common, 0.351% - 4.86% x x x x x x x x x x x
Anxiety depression x x
Nephropathy Nephropathy 0.468% - 5.07% 0.233% - 3.89% x x x x x x x x x x x x x x
Osteoporosis Osteoporosis common, 0.125% - 6% x x x x x x x x x x x x x x x x x x
Angiopathy Angiopathy 2.3% - 53.6% 2.88% - 47.8% x x x x x x x x x x x x x x x x x x
Cerebrovascular accident Cerebrovascular accident uncommon, 1.15% - 2.86% x x x x x x x x x x x x x
Pruritus Pruritus uncommon, 1% - 5% x x x x x x x x x x x x x x x x x x x
Breast pain Breast pain uncommon, 0.0252% - 7% x x x x x x x x x x x x x x x x x x x
Vaginal discharge Vaginal discharge uncommon, 2% x x x x x x x x x x x x x x x x
Angina pectoris Angina pectoris 0.176% - 24% x x x x x x x x x x x x x x x x x x x
Vulvovaginal discomfort Vaginal irritation 0.0502% - 4.53% x x x x x x x x x x x x x
Myocardial infarction Myocardial infarction 0.276% - 15% x x x x x x x x x x x x x x x x x x x
Acute coronary syndrome Myocardial infarction 0.276% - 15% x x x x x x x x x x x x x x x x x x x
Cataract Cataract uncommon, 0.654% - 2.21% x x x x x x x x x x x x x x x
Embolism Thromboembolism 0.6% x
Thromboembolic event x x x x x x x x x x x x x x x x x x x
Embolism venous Thromboembolism 0.6% x
Anxiety Anxiety uncommon x x x x x x x x x x x x x x x x x
Dysgeusia Dysgeusia uncommon x x x x x x x x x x x x x x x
Oedema Oedema uncommon, 0.0251% - 18.4% 0.117% - 16.2% x x x x x x x x x x x x x x x x x x x
Body temperature increased Body temperature increased uncommon x x x x x x x x x x x x x x x
Leukopenia Leukopenia uncommon x x x x x x x x x x x x x x x
Palpitations Palpitations uncommon x x x x x x x x x x x x x x x
Stomatitis Stomatitis uncommon x x x x x x x x x x x x x x x
Tachycardia Tachycardia uncommon x x x x x x x x x x x x x x x
Thirst Thirst uncommon x x x x x x x x x x x x x x x
Thrombophlebitis Thrombophlebitis uncommon x x x x x x x x x x x x x x x x x x x
Pollakiuria Pollakiuria uncommon x x x x x x x x x x x x x x x
Urticaria Urticaria uncommon x x x x x x x x x x x x x
Dry mouth Dry mouth uncommon x x x x x x x x x x x x x x x
Dry skin Dry skin uncommon x x x
Memory impairment Memory impairment uncommon x x x x x x x x x x x x x x x
Dysaesthesia Dysaesthesia uncommon x x x x x x x x x x x x x x x
Tumour pain Tumour pain uncommon x x x
Mucosal dryness Mucosal dryness uncommon x x x
Vaginal haemorrhage Vaginal haemorrhage uncommon, 0.0252% - 13.1% 0.194% - 6.65% x x x x x x x x x x x x x x x x x x x x
Myocardial ischaemia Myocardial ischaemia 0.245% - 0.368% x x x x x x x x x x x x x x x x
Anaphylactic shock Anaphylactic shock very rare, postmarketing x x x x x x x x x x x x x
Angioedema Angioedema very rare, postmarketing x x x x x x x x x x x x x
Carpal tunnel syndrome Carpal tunnel syndrome postmarketing x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis very rare, postmarketing x x x x x x x x x x x x
Erythema multiforme Erythema multiforme very rare, postmarketing x x x x x x x x x x x
Hepatitis Hepatitis very rare, postmarketing x x x x x x x x x x x x
Pulmonary embolism Pulmonary embolism rare x x x x x x x x x x x x x x x x x x x
Arterial thrombosis Arterial thrombosis rare x x x x x x x x x x x x x x x
Trigger finger Trigger finger postmarketing x x x x x x
Vision blurred Vision blurred postmarketing x x x x x x x x x x x x x x x x x
Cerebral infarction Cerebrovascular infarction rare x x x
Bone disorder Bone disorder x
Breast disorder Breast disorder x x x x x x x x x x x x x x x x x x
Cardiovascular disorder Cardiovascular disorder x x x x x x x x x x
Transient ischaemic attack Transient ischaemic attack x x x x x x x x x x x x x x x x
Connective tissue disorder Connective tissue disorder x x x x x x x x x x x x x x x x x
Coronary artery disease Coronary heart disease x x x x x x x x x x x x x x x x
Cyst Cyst x x x
Endometrial hyperplasia Endometrial hyperplasia x x x x x x x x x x
Eye disorder Eye disorder x x x
Cardiac disorder Cardiac disorder x x x
Cardiac failure Cardiac failure x x x x x x x x x x x x x x x
Hemiparesis Hemiparesis x x x x x x x x x x x x x x x x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Hypercalcaemia Hypercalcaemia x x x x x x x x x x x x x x x x
Hypoaesthesia Hypoaesthesia x x x x x x x x x x x x x x x
Irritability Irritability x x x x x x x x x x x x x x x
Mediastinal disorder Mediastinal disorder x x x x x x x x x x x x x x x x x x
Menopause Menopause x x x x x x x
Musculoskeletal pain Musculoskeletal pain x x x x x x x x x x x
Neoplasm Neoplasm x x x x x x x x x x x x x x x x x x
Nervousness Nervousness x x x x x x x x x x x x x x x
Tension Nervousness x x x x x x x x x x x x x x x
Paraesthesia Paraesthesia x x x x x x x x x x x x x x x
Phlebitis Phlebitis x
Pleural effusion Pleural effusion x x x x x x x x x x x x x x x x
Polyp Polyp x x x
Urethral disorder Urinary tract disorder x x x
Urinary tract disorder Urinary tract disorder x x x
Venous thrombosis Venous thrombosis x x x x x x x x x x x x x x x x
Vertigo Vertigo x x x x x x x x x x x x x x x x
Portal vein thrombosis Portal vein thrombosis x x x x x x x x x x x x x x x x
Malnutrition Malnutrition x x x x x x x x x x x x x x x x x x
Rash vesicular Rash vesicular x x x x x x x x x x x x x
Rash erythematous Rash erythematous x x x x x x x x x x
Eye irritation Eye irritation x x x x x x x x x x x x x x x
Gravitational oedema Gravitational oedema x x x x x x x x x x
Dermatitis psoriasiform Dermatitis psoriasiform x x x x x x x x
Hepatobiliary disease Hepatobiliary disease x x x
Rash maculo-papular Rash maculo-papular x x x x x x x x x x
Endometrial cancer Endometrial cancer x x x x
Haemorrhagic stroke Haemorrhagic stroke x x x x x x x x x x x x x x x x
Cerebral haemorrhage Haemorrhagic stroke x x x x x x x x x x x x x x x x
Cancer pain Cancer pain x x x x x x x x x x x x
Oestrogen deficiency Oestrogen deficiency x x x x x x x x x x x x x x
Oestrogenic effect Oestrogenic effect x x x x x x x x x x x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Letrozole

Side effects:36
Source:BC Cancer

LETROZOLE / FEMARA

Side effects:68
Source:FDA

LETROZOLE / FEMARA

Side effects:76
Source:FDA

LETROZOLE / FEMARA

Side effects:88
Source:FDA

Letrozole / Letraccord, Film coated tablet

Side effects:93
Source:Medsafe

LETROZOLE / FEMARA

Side effects:95
Source:FDA

Letrozole / Femolet

Side effects:95
Source:medicines.org.au

letrozole tablets / Femara

Side effects:118
Source:FDA

LETROZOLE / FEMARA

Side effects:118
Source:FDA

LETROZOLE

Side effects:119
Source:FDA Structured Product Label

LETROZOLE

Side effects:119
Source:FDA Structured Product Label

LETROZOLE

Side effects:120
Source:FDA Structured Product Label

LETROZOLE

Side effects:120
Source:FDA Structured Product Label

LETROZOLE

Side effects:121
Source:FDA Structured Product Label

LETROZOLE

Side effects:121
Source:FDA Structured Product Label

letrozole

Side effects:128
Source:FDA Structured Product Label

LETROZOLE

Side effects:129
Source:FDA Structured Product Label

LETROZOLE

Side effects:129
Source:FDA Structured Product Label

LETROZOLE

Side effects:130
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label