Baclofen

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Hypotonia def Hypotonia def 2.4% - 34.7% x x x x
Muscle relaxant therapy Hypotonia def 2.4% - 34.7% x x x x
Somnolence def Somnolence def rare, 5.7% - 20.9% x x x x
Drowsiness def x x x x x
Headache def Headache def 1.6% - 10.7% x x x x x x x x
Nausea def Nausea def 1.4% - 10.5% x x x x x x x x
Vomiting def Vomiting def 1.6% - 10.5% x x x x x x x
Convulsion def Convulsion def 0.5% - 10% x x
Seizures def x x x x
Dizziness def Dizziness def 1.7% - 8% x x x x x x x x
Syncope def x x x x x x
Lightheadedness x
Urinary retention def Urinary retention def 0.7% - 8% x x x x x
Paraesthesia def Paraesthesia def 0.7% - 6.7% x x x x x
Tingling sensation def x
Hypertonia def Hypertonia def 0% - 6% x x
Constipation def Constipation def 0.2% - 5.1% x x x x x x x x
Pruritus def Pruritus def 0% - 4% x x x x x x x x
Hypoxia def Hypoventilation def 0.2% - 4% x x
Hypoventilation def Hypoventilation def 0.2% - 4% x x
Respiratory failure def Hypoventilation def 0.2% - 4% x x
Speech disorder def Speech disorder def 0% - 3.5% x x
Oedema def Oedema def rare, 0% - 3.3% x x x x x x x x
Dry mouth def Dry mouth def rare, 0% - 3.3% x x x x x x x
Oedema peripheral def Oedema peripheral def 0% - 3.3% x x
Ankle edema x x x x x
Death Death 0.2% - 3% x x
Salivary hypersecretion def Salivation def 0% - 2.7% x x
Salivary hypersecretion def 0% - 2.7% x x
Confusional state def Confusional state def rare, 0.5% - 2.3% x x x x x x x x
Feeling abnormal Confusional state def rare, 0.5% - 2.3% x x x x x x x x
Malaise def x x
Diarrhoea def Diarrhoea def rare, 0% - 2.3% x x x x x x x
Asthenia def Asthenia def 0% - 2% x x
Fatigue def rare x x x x x x
Weakness def x x x x x x
Back pain def Back pain def 0.7% - 2% x x
Hypotension def Hypotension def 0.2% - 2% x x x x x x x x
Incontinence def Incontinence def rare, 0% - 2% x x x
Pneumonia def Pneumonia def 0% - 2% x x
Urinary incontinence def Urinary incontinence def rare, 0% - 2% x x x
Dysuria def Urination impaired 0% - 2% x x
Dysuria def x x x x
Erectile dysfunction def Erectile dysfunction def 0.2% - 1.6% x x x x x
Insomnia def Insomnia def rare, 0% - 1.6% x x x x x x x x
Coma def Coma def 0% - 1.5% x x x
Tremor def Tremor def 0% - 1.3% x x x x x x
Chills def Chills def 0% - 1.3% x x
Agitation def Agitation def 0% - 1.3% x x
Excitement x x x
Thinking abnormal Thinking abnormal 0.5% - 1.3% x x
Mental disability Thinking abnormal 0.5% - 1.3% x x
Dyspnoea def Dyspnoea def 0% - 1.2% x x x x x x x
Urticaria def Urticaria def rare, 0.2% - 1.2% x x x
Decreased appetite Anorexia def 0% - 0.9% x x x x x
Decreased appetite rare x
Anxiety def Anxiety def rare, 0.2% - 0.9% x x x
Diplopia def Diplopia def 0% - 0.9% x x x x x x
Autonomic nervous system imbalance Dysautonomia def 0.2% - 0.9% x x
Pollakiuria def Pollakiuria def 0% - 0.9% x x x x x x x
Body temperature increased def Body temperature increased def 0.2% - 0.7% x x
Hypertension def Hypertension def 0.2% - 0.6% x x x
Hallucination def Hallucination def rare, 0.3% - 0.5% x x x x x x x
Alopecia def Alopecia def rare x x x
Dysphagia def Dysphagia def rare x x x
Dehydration def Dehydration def rare x x x
Embolism def Embolism def rare x
Embolus def x x
Fatigue def Fatigue def rare x x x x x x
Lassitude def x
Exhaustion x
Flushing def Flushing def rare x
Body temperature decreased def Body temperature decreased def rare x x x
Hypothermia Body temperature decreased def rare x x x
Nystagmus def Nystagmus def rare x x x x x x x
Pallor def Pallor def rare x x x
Pulmonary embolism def Pulmonary embolism def rare x x x
Completed suicide Suicide def rare x x x
Thrombosis def Thrombosis def rare x
Venous thrombosis def Venous thrombosis def rare x
Deep vein thrombosis def Deep vein thrombosis def rare x
Deep thrombophlebitis x x
Disorientation Disorientation rare x
Dysphoria Dysphoria rare x
Respiratory depression Respiratory depression rare x x
Pulmonary function test decreased Respiratory depression rare x x
Euphoric mood def Euphoric mood def rare x x x x x x x
Bladder pain def Bladder spasm def rare x
Bladder spasm def Bladder spasm def rare x
Face oedema def Face oedema def rare x x x
Sexual dysfunction Sexual dysfunction rare x
Hyperhidrosis def Sweating increased rare x x x x x
Hyperhidrosis def x
Sweating def x x x x x x
Amnesia def Memory loss rare x
Amnesia def x x
Ileus def Ileus def rare x x x
Psychotic disorder def Paranoia def rare x
Paranoia def Paranoia def rare x
Paranoid reaction x x
Abdominal pain def Abdominal pain def x x x x x
Gastrointestinal pain def Abdominal pain def x x x x x
Ageusia def Ageusia def x x
Albuminuria def Albuminuria def x x
Anaemia def Anaemia def x x
Apnoea def Apnoea def x x
Arachnoiditis def Arachnoiditis def x
Arrhythmia def Arrhythmia def x x
Ataxia def Ataxia def x x x x x x
Mental disorder def Mental disorder def x
Neoplasm malignant def Carcinoma def x x
Cardiac output decreased def Cardiac output decreased def x
Chest pain def Chest pain def x x x x x x
Dermatitis def Dermatitis def x x
Rash def x x x x x x x
Dermatitis contact def Dermatitis contact def x x
Dysarthria def Dysarthria def x x x
Slurred speech x x x x
Osteoarthritis def Dysarthria def x x x
Dyspepsia def Dyspepsia def x x
Digestion impaired x
Enuresis def Enuresis def x x x x
Epilepsy def Epilepsy def x x x
Rash def Rash def x x x x x x x
Faecal incontinence def Faecal incontinence def x x
Flatulence def Flatulence def x x
Gastroenteritis def Gastroenteritis def x x
Gastrointestinal haemorrhage def Gastrointestinal haemorrhage def x x
Haematuria def Haematuria def x x x x x
Haemorrhage def Haemorrhage def x x
Haemoglobin def Haemorrhage def x x
Hyperglycaemia def Hyperglycaemia def x x
Hyperventilation def Hyperventilation def x x
Orthostatic hypotension def Orthostatic hypotension def x x
Conversion disorder def Hysteria def x x
Infection def Infection def x x x
Influenza def Influenza def x x
Ischaemia def Ischaemia def x x
Nephrolithiasis def Calculus of kidney def x x
Leiomyoma def Leiomyoma def x x
Uterine leiomyoma def Leiomyoma def x x
Lethargy def Lethargy def x
Leukocytosis def Leukocytosis def x x
Meningitis def Meningitis def x x x
Miosis def Miosis def x x x
Mydriasis def Mydriasis def x x x
Nasal congestion def Nasal congestion def x x x x x
Nightmare def Nightmare def x
Hypoaesthesia def Numbness def x
Sensory loss Numbness def x
Nocturia def Nocturia def x x x
Oliguria def Oliguria def x x
Palpitations def Palpitations def x x x x x x
Personality disorder def Personality disorder def x x
Petechiae def Petechiae def x x
Pneumonia aspiration def Pneumonia aspiration def x
Eyelid ptosis def Ptosis def x x
Uterovaginal prolapse Ptosis def x x
Renal failure def Renal failure def x x
Respiratory disorder def Respiratory disorder def x x
Rhinitis def Rhinitis def x x
Skin ulcer def Skin ulcer def x x
Strabismus def Strabismus def x x x
Shock def Syncope def x x x x x x
Syncope def Syncope def x x x x x x
Loss of consciousness def Syncope def x x x x x x
Tachycardia def Tachycardia def x x
Thrombophlebitis def Thrombophlebitis def x x
Tinnitus def Tinnitus def x x x x x
Tongue disorder Tongue disorder x x
Ulcer def Ulcer def x x
Vaginal inflammation def Vaginal inflammation def x x
Vaginal infection def Vaginal inflammation def x x
Vasodilation procedure Vasodilation def x
Visual impairment def Visual impairment def x x
Visual disturbance x
Visual acuity reduced Visual impairment def x x
Blindness def Visual impairment def x x
Weight increased def Weight increased def x x x x x
Weight decreased def Weight decreased def x x
Ventricular arrhythmia def Ventricular arrhythmia def x x
Mood swings Mood swings x x
Affect lability Mood swings x x
Photophobia def Photophobia def x x
Musculoskeletal stiffness Neck stiffness x x
Nuchal rigidity Neck stiffness x x
Muscular weakness def Muscular weakness def x
Drug ineffective Lack of drug effect x x
Opisthotonus Opisthotonus x x
Blood alkaline phosphatase increased def Phosphatase alkaline increased x x x
Hyporeflexia Hyporeflexia x x
Aspartate aminotransferase increased def Aspartate aminotransferase increased def x x x
Accommodation disorder Accommodation disorder x x
Malaise def Sickness x
Malaise def x x
Discomfort def Malaise def x x
Ill-defined disorder Malaise def x x
Myalgia def Myalgia def x x x x
Musculoskeletal discomfort Myalgia def x x x x
Muscle twitching def Muscle twitching def x x
Respiratory rate decreased def Respiratory rate decreased def x
Gastrointestinal disorder def Digestion impaired x
Retching def Retching def x
Joint swelling Ankle edema x x x x x
Wound dehiscence def Wound dehiscence def x x
Major depression def Depressive type psychosis x x
Vision blurred def Vision blurred def x x x x
Akathisia def Akathisia def x x
Dystonia def Dystonia def x x x
Bradycardia def Bradycardia def x x x
Coordination abnormal Coordination abnormal x x x x x
Gait disturbance def Gait disturbance def x x
Sedation Sedation x x
Aspiration Aspiration x x
Cerebral ischaemia def Cerebral ischaemia def x x
Haematochezia def Blood in stool x x x
Drug dependence def Drug dependence def x x
Ejaculation disorder def Abnormal ejaculation x x
Indication Labels
Cerebral palsy def x x x
Cerebrovascular accident def x x x
Clonus def x x
Encephalopathy def x
Hypoxic brain damage x
Multiple sclerosis def x x x x
Muscle rigidity def x x
Muscle spasms def x x x
Muscle spasticity def x x x x x x
Pain def x x
Paralysis def x x x
Retinitis pigmentosa def x x x x x x
Spinal cord disorder def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: M03BX01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. BACLOFEN / LIORESAL D.S. TAB 20MG : 42 side effects (Health Canada)
  2. BACLOFEN : 25 side effects (FDA XML label)
  3. BACLOFEN / PHL-BACLOFEN : 55 side effects (Health Canada)
  4. Baclofen : 57 side effects (FDA XML label)
  5. baclofen : 57 side effects (FDA XML label)
  6. BACLOFEN / LIORESAL INTRATHECAL 2MG/ML : 64 side effects (Health Canada)
  7. baclofen : 130 side effects (FDA XML label)
  8. baclofen : 132 side effects (FDA XML label)