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Lomitapide

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Abdominal distension Abdominal distension x x
Abdominal pain Abdominal pain x x
Gastrointestinal pain Abdominal pain x x
Aerophagia Aerophagia x
Anaemia Anaemia x
Angina pectoris Angina pectoris x
Arthralgia Arthralgia x
Musculoskeletal discomfort Arthralgia x
Myalgia x
Asthenia Asthenia x
Fatigue x x
Back pain Back pain x
Blister Blister x
Dermatitis bullous Blister x
Chest pain Chest pain x x
Infection Infection x x
Connective tissue disorder Connective tissue disorder x
Constipation Constipation x x
Dehydration Dehydration x
Diarrhoea Diarrhoea x x
Dizziness Dizziness x x
Dyspepsia Dyspepsia x x
Ecchymosis Ecchymosis x
Eructation Eructation x
Gastrooesophageal reflux disease Reflux esophagitis x
Gastrooesophageal reflux disease x x
Eye disorder Eye disorder x
Fatigue Fatigue x x
Body temperature increased Body temperature increased x x
Flatulence Flatulence x x
Gastritis Gastritis x
Gastroenteritis Gastroenteritis x x
Gastrointestinal disorder Gastrointestinal disorder x x
Reaction gastrointestinal x
Headache Headache x x
Cardiac disorder Cardiac disorder x
Haematemesis Haematemesis x
Haematuria Haematuria x
Hepatomegaly Hepatomegaly x
Hyperhidrosis Hyperhidrosis x
Influenza Influenza x x
Lower gastrointestinal haemorrhage Lower gastrointestinal haemorrhage x
Mediastinal disorder Mediastinal disorder x
Musculoskeletal disorder Musculoskeletal disorder x
Nasal congestion Nasal congestion x
Nasopharyngitis Nasopharyngitis x x
Nausea Nausea x x
Nervous system disorder Nervous system disorder x x
Pain in extremity Pain in extremity x
Palpitations Palpitations x
Paraesthesia Paraesthesia x
Sinusitis Sinusitis x
Muscle spasms Muscle spasms x
Gastric dilatation Gastric dilatation x
Stomach dilation procedure Gastric dilatation x
Gastric disorder Gastric disorder x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Vertigo Vertigo x
Vomiting Vomiting x x
Weight decreased Weight decreased x x
Dry mouth Dry mouth x
Chills Chills x
Migraine Migraine x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x
Liver function test abnormal Liver function test abnormal x
Prothrombin level increased Prothrombin level increased x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Alanine aminotransferase increased Alanine aminotransferase increased x x
Dry skin Dry skin x
Joint swelling Joint swelling x
Malnutrition Malnutrition x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Malaise Malaise x
Discomfort Malaise x
Discomfort x x
Feeling abnormal Malaise x
Ill-defined disorder Malaise x
Myalgia Myalgia x
Muscle twitching Muscle twitching x
Increased appetite Increased appetite x
Decreased appetite Decreased appetite x
Abdominal discomfort Abdominal discomfort x x
Abdominal pain upper Abdominal pain upper x
Abdominal pain lower Abdominal pain lower x
Abdominal tenderness Abdominal tenderness x
Proctalgia Rectal tenesmus x x
Rectal tenesmus Rectal tenesmus x x
Anorectal discomfort Rectal tenesmus x x
Rash erythematous Rash erythematous x
Hepatotoxicity Hepatotoxicity x x
Hepatic enzyme increased Hepatic enzyme increased x
Early satiety Early satiety x
Frequent bowel movements Frequent bowel movements x
Haemorrhoidal haemorrhage Haemorrhoidal haemorrhage x
Hepatobiliary disease Hepatobiliary disease x
Eye swelling Eye swelling x
Faeces hard Faeces hard x
Xanthoma Xanthoma x
Blood bilirubin increased Blood bilirubin increased x
Papule Papule x
Defaecation urgency Defaecation urgency x x
Transaminases increased Transaminases increased x x
Pulmonary function test abnormal Pulmonary function test abnormal x
Gait disturbance Gait disturbance x
International normalised ratio abnormal International normalised ratio abnormal x
Drug interaction Drug interaction x
Pharyngeal lesion Pharyngeal lesion x
White blood cell count decreased White blood cell count decreased x
White blood cell count increased White blood cell count increased x
Infestation Infestation NOS x
Blood alkaline phosphatase increased Blood alkaline phosphatase increased x
International normalised ratio increased International normalised ratio increased x
Neutrophil count decreased Neutrophil count decreased x
Blood potassium decreased Blood potassium decreased x
Carotene decreased Carotene decreased x
Laryngeal pain Pharyngolaryngeal pain x
Neutrophil percentage increased Neutrophil percentage increased x
Vitamin E decreased Vitamin E decreased x
Vitamin K decreased Vitamin K decreased x
Gastrointestinal infection Gastrointestinal infection x
Epigastric discomfort Epigastric discomfort x
Regurgitation Regurgitation x
Hepatic steatosis Hepatic steatosis x x
Somnolence Somnolence x
Upper-airway cough syndrome Upper-airway cough syndrome x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

LOMITAPIDE

Side effects:37
Source:FDA Structured Product Label

lomitapide / lomitapide

Side effects:108
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
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    frequent (1% to 100%)
    infrequent (0.1% to 1%)
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    postmarketing
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    no frequency information
    not found on label