| MedDRA Preferred Term | Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 
| Pneumonia klebsiella | Pneumonia klebsiella | 40% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysgeusia | Dysgeusia | common, 5% |  |  |  |  |  | x | x |  |  |  |  | x |  | x |  |  |  |  |  |  |  | 
| Bad taste |  |  |  | x | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Endophthalmitis | Ocular hyperaemia | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Endophthalmitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ocular hyperaemia | Ocular hyperaemia | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Corneal deposits | Corneal deposits | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ocular discomfort | Ocular discomfort | common |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nasopharyngitis | Nasopharyngitis | 2.6% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Nausea | Nausea | uncommon — 1.3% - 5.2% |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Fungal infection | Fungal infection | 1.6% - 2.6% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Vaginal inflammation | Vaginal inflammation | 2% |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Vaginal infection | Vaginal inflammation | 2% |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Vaginitis bacterial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Vaginal infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Pollakiuria | Micturition urgency | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Pollakiuria |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | x | x | 
| Micturition urgency | Micturition urgency | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Sensation of foreign body | Sensation of foreign body | 1.8% - 2% |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Discomfort | Discomfort | 1.7% - 9.7% | 7.9% |  | x | x |  |  |  |  | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Malaise | postmarketing, uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Diarrhoea | Diarrhoea | postmarketing — 1% - 2.3% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Headache | Headache | uncommon, 1% - 3% |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Liver function test abnormal | Liver function test abnormal | 1.3% |  |  |  | x |  | x |  |  | x | x | x | x | x |  | x | x | x | x |  | x | x | 
| Hyperaemia | Hyperaemia | 1.2% | 1.4% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema | Erythema | 1.2% | 1.4% |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Redness | 1.2% | 1.4% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dizziness | Dizziness | rare — 1% - 2% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Syncope | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Lightheadedness | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Dermatitis | Rash | postmarketing — 1% - 1.8% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dermatitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Rash | Rash | postmarketing — 1% - 1.8% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Eruption | postmarketing |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  |  | 
| Vomiting | Vomiting | postmarketing — 1% - 2% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Injection site pain | Injection site pain | 1% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pruritus | Pruritus | uncommon, 1.1% - 1.2% | 1.9% |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Eosinophilia | Eosinophilia | postmarketing — 0.6% |  |  |  |  | x | x |  | x | x |  | x |  | x | x | x | x | x | x |  | x | x | 
| Abdominal pain | Abdominal pain | rare, uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Gastrointestinal pain | Abdominal pain | rare, uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Decreased appetite | Anorexia | uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | 
| Decreased appetite | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye pruritus | Eye pruritus | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Superinfection | Superinfection | uncommon |  | x |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Photophobia | Photophobia | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Conjunctival oedema | Conjunctival oedema | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Chemosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye pain | Eye pain | uncommon |  |  |  | x |  |  |  | x | x | x | x |  | x | x | x | x | x | x |  | x | x | 
| Lacrimation increased | Lacrimation increased | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Lacrimation |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eyelid oedema | Eyelid oedema | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Visual acuity reduced | Visual acuity reduced | uncommon |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Keratopathy | Keratopathy | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema of eyelid | Erythema of eyelid | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye swelling | Eye swelling | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood bilirubin increased | Blood bilirubin increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Dry eye | Dry eye | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye discharge | Eye discharge | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vital dye staining cornea present | Corneal staining | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sleep disorder | Sleep disorder | uncommon |  |  |  |  | x |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Corneal infiltrates | Corneal infiltrates | uncommon |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Foreign body sensation in eyes | Foreign body sensation in eyes | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eyelid margin crusting | Eyelid margin crusting | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Renal failure | Renal impairment | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Renal failure | postmarketing — uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Renal impairment | Renal impairment | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Kidney function abnormal |  |  |  |  |  |  | x |  |  |  |  |  | x |  | x |  |  |  |  |  |  |  | 
| Eyelid exfoliation | Eyelid exfoliation | uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Leukopenia | Leukopenia | postmarketing — 0.4% |  |  |  |  | x |  |  |  | x | x | x |  | x | x | x | x | x | x |  | x |  | 
| Thrombocytopenia | Thrombocytopenia | postmarketing — uncommon |  |  |  |  | x | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Vertigo | Vertigo | postmarketing — uncommon |  |  |  |  | x |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Disorientation | Disorientation | postmarketing — uncommon |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysaesthesia | Dysaesthesia | postmarketing — uncommon |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Liver disorder | Hepatic impairment | postmarketing — uncommon |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Liver disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Acidosis | Acidosis | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Agranulocytosis | Agranulocytosis | very rare, postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Albuminuria | Albuminuria | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Anaphylactic shock | Anaphylactic shock | very rare — rare |  |  |  |  | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Anaphylactoid reaction |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Anaemia | Anaemia | postmarketing, rare |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x |  | 
| Haemolytic anaemia | Haemolytic anaemia | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Angina pectoris | Angina pectoris | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Angioedema | Angioedema | postmarketing, rare |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Anosmia | Anosmia | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Anthrax | Anthrax | postmarketing |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  |  |  | 
| Anxiety | Anxiety | postmarketing, rare |  |  |  |  | x | x | x | x |  |  |  | x |  | x |  |  |  |  | x | x | x | 
| Phobia | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Arrhythmia | Arrhythmia | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Arthralgia | Arthralgia | postmarketing, uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Ache wrists |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Musculoskeletal discomfort | Arthralgia | postmarketing, uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Myalgia | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Arthritis | Arthritis | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Asthenia | Asthenia | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Fatigue |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Asthenopia | Asthenopia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ataxia | Ataxia | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Atrial flutter | Atrial flutter | postmarketing |  |  |  | x |  |  | x |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Blister | Blister | rare |  |  |  |  | x | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Dermatitis bullous | Blister | rare |  |  |  |  | x | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Vesiculobullous rash |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Bone disorder | Bone disorder | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bronchospasm | Bronchospasm | postmarketing |  |  |  | x |  |  | x |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Candida infection | Candida infection | postmarketing |  |  |  |  |  | x | x |  | x | x | x | x | x |  | x | x | x | x | x |  | x | 
| Oral candidiasis |  |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Vulvovaginal candidiasis | Vaginal moniliasis | postmarketing, 1% - 2% |  |  |  |  |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Vulvovaginal mycotic infection | Vaginal moniliasis | postmarketing, 1% - 2% |  |  |  |  |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Confusional state | Confusional state | postmarketing — uncommon |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Feeling abnormal | Confusional state | postmarketing — uncommon |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Malaise | postmarketing, uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Conjunctivitis | Conjunctivitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Constipation | Constipation | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | 
| Corneal disorder | Corneal disorder | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysphagia | Dysphagia | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Delirium | Delirium | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Dermatitis exfoliative | Dermatitis exfoliative | postmarketing, rare |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Diplopia | Diplopia | postmarketing, rare |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Somnolence | Drowsiness | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Somnolence |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x |  | x | x | 
| Dyspepsia | Dyspepsia | postmarketing — 1% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dyspnoea | Dyspnoea | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Ear pain | Ear pain | rare |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Oedema | Oedema | postmarketing — uncommon |  |  | x |  | x | x | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Panophthalmitis | Endophthalmitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Toxic epidermal necrolysis | Toxic epidermal necrolysis | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Necrolysis epidermal |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Grand mal convulsion | Grand mal convulsion | postmarketing |  |  |  | x |  | x |  |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Epistaxis | Epistaxis | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Erythema multiforme | Erythema multiforme | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Stevens-Johnson syndrome | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Erythema multiforme minor | very rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema nodosum | Erythema nodosum | very rare, postmarketing |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Body temperature increased | Body temperature increased | postmarketing, uncommon |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Drug fever |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Flatulence | Flatulence | postmarketing, uncommon |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | 
| Flushing | Flushing | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Gastrointestinal haemorrhage | Gastrointestinal haemorrhage | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Gout | Gout | postmarketing |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  | x |  |  | 
| Gout flare |  |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Gynaecomastia | Gynaecomastia | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Hallucination | Hallucination | postmarketing — uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Cardiac disorder | Cardiac disorder | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Cardiac murmur | Cardiac murmur | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Haematuria | Haematuria | postmarketing — 1.2% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Haemoptysis | Haemoptysis | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Haemorrhage | Haemorrhage | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Haemoglobin | Haemorrhage | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Hepatitis | Hepatitis | postmarketing, rare |  |  |  | x | x | x |  |  | x | x | x | x | x | x | x | x | x |  | x | x | x | 
| Hiccups | Hiccups | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hordeolum | Hordeolum | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hyperaesthesia | Hyperaesthesia | very rare, postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hyperglycaemia | Hyperglycaemia | rare |  |  |  |  | x | x |  |  |  |  |  | x |  |  |  |  |  | x |  |  | x | 
| Hyperhidrosis | Hyperhidrosis | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sweating | postmarketing, rare |  |  |  | x | x | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x |  | 
| Sweating increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hypersensitivity | Hypersensitivity | postmarketing, rare |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypertension | Hypertension | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypoaesthesia | Hypoaesthesia | postmarketing, rare |  |  |  |  | x | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypoglycaemia | Hypoglycaemia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | 
| Hypotension | Hypotension | postmarketing — uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Orthostatic hypotension | Orthostatic hypotension | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x |  |  | 
| Immune system disorder | Immune system disorder | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Intestinal perforation | Intestinal perforation | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Jaundice | Jaundice | postmarketing — uncommon |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Jaundice cholestatic | Jaundice cholestatic | postmarketing |  |  |  | x |  | x | x |  | x | x | x | x | x |  | x | x | x | x | x | x |  | 
| Keratitis | Keratitis | rare |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Keratoconjunctivitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nephrolithiasis | Calculus of kidney | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Lethargy | Lethargy | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Leukocytosis | Leukocytosis | postmarketing, rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Methaemoglobinaemia | Methaemoglobinaemia | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x |  | x | x | 
| Muscle spasms | Cramp muscle | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Muscle spasms |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Night cramps |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Hypertonia | Hypertonia | postmarketing, rare |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Myasthenia gravis | Myasthenia gravis | very rare, postmarketing |  |  |  |  | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Myocardial infarction | Myocardial infarction | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Acute coronary syndrome | Myocardial infarction | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Myoclonus | Myoclonus | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Nephritis | Nephritis | postmarketing |  |  |  | x |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tubulointerstitial nephritis | Nephritis interstitial | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tubulointerstitial nephritis | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nervous system disorder | Nervous system disorder | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Neutropenia | Neutropenia | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nightmare | Nightmare | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Nystagmus | Nystagmus | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Pain | Pain | postmarketing, uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Stinging |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Palpitations | Palpitations | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Pancreatitis | Pancreatitis | very rare — rare |  |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Pancytopenia | Pancytopenia | very rare — 0.1% |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Bone marrow depression | very rare — rare |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Paraesthesia | Paraesthesia | postmarketing, rare |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tingling sensation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Neuropathy peripheral | Neuropathy peripheral | postmarketing |  |  |  |  | x |  |  |  | x | x | x | x | x |  | x | x | x | x | x |  | x | 
| Neuritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Petechiae | Petechiae | very rare — rare |  |  |  | x | x | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Phlebitis | Phlebitis | postmarketing |  |  |  | x |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Pleural effusion | Pleural effusion | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Polyuria | Polyuria | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Urine output increased | Polyuria | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Psychotic disorder | Psychotic disorder | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Paranoia | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Pulmonary embolism | Pulmonary embolism | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Purpura | Purpura | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Vascular purpura | Purpura | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Rhinitis | Rhinitis | rare |  |  |  |  |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Convulsion | Convulsion | postmarketing — uncommon |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Convulsive seizure |  |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Shock | Shock | postmarketing |  |  |  |  |  | x | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Syncope | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Status epilepticus | Status epilepticus | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | x | 
| Stevens-Johnson syndrome | Stevens-Johnson syndrome | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Syncope | Syncope | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Loss of consciousness | Syncope | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Loss of consciousness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Tachycardia | Tachycardia | postmarketing — uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tendonitis | Tendonitis | very rare, postmarketing |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Tinnitus | Tinnitus | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Torsade de pointes | Torsade de pointes | postmarketing |  |  |  |  | x | x |  |  | x | x | x | x | x |  | x | x | x | x | x |  | x | 
| Tremor | Tremor | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Trembling |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood uric acid increased | Uric acid level increased | postmarketing |  |  |  |  |  |  |  |  | x | x | x |  | x |  | x | x | x | x |  | x |  | 
| Hyperuricaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Urticaria | Urticaria | postmarketing — uncommon |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Uveitis | Uveitis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vulvovaginal pruritus | Vaginal itching | postmarketing, 1% |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  | x |  |  | 
| Vasculitis | Vasculitis | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Dry mouth | Dry mouth | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  | x |  |  |  |  | x | x | x | 
| Cerebral thrombosis | Cerebral thrombosis | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Urinary retention | Urinary retention | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Chills | Chills | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Rigors |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Hepatic failure | Hepatic failure | very rare, postmarketing |  |  |  |  | x | x |  |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Ventricular arrhythmia | Ventricular arrhythmia | postmarketing |  |  |  |  | x | x |  |  |  |  | x |  | x |  | x | x | x | x |  |  | x | 
| Agitation | Agitation | postmarketing — 1.1% |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Photopsia | Photopsia | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Cystitis haemorrhagic | Cystitis haemorrhagic | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Clostridium difficile colitis | Antibiotic associated colitis | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Stomatitis | Mouth ulceration | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Stomatitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Mouth ulceration | Mouth ulceration | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Ulcerative stomatitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Migraine | Migraine | very rare — rare |  |  |  | x | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Amylase increased | Amylase increased | rare |  |  |  |  | x |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Crystalluria | Crystalluria | postmarketing, rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Fixed eruption | Fixed eruption | postmarketing |  |  |  |  |  | x |  |  | x | x | x |  | x | x | x | x | x | x |  | x | x | 
| Red blood cell sedimentation rate increased | Red blood cell sedimentation rate increased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  | x | x | 
| Ventricular extrasystoles | Ventricular extrasystoles | postmarketing |  |  |  | x |  |  | x |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Ventricular bigeminy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Mania | Manic psychosis | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Hepatic necrosis | Hepatic necrosis | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Aspartate aminotransferase increased | Aspartate aminotransferase increased | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Alanine aminotransferase increased | Alanine aminotransferase increased | postmarketing |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Tendon rupture | Tendon rupture | very rare — rare |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Polyneuropathy | Polyneuropathy | postmarketing |  |  |  |  | x |  |  |  |  |  | x |  | x |  | x | x | x | x |  |  | x | 
| Polyneuritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Pneumonia anthrax | Pneumonia anthrax | postmarketing |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  |  |  | 
| Respiratory arrest | Respiratory arrest | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Joint stiffness | Joint stiffness | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Photosensitivity reaction | Photosensitivity reaction | rare |  |  |  |  |  | x | x |  |  |  |  | x |  | x |  |  |  |  |  |  |  | 
| Photosensitivity | postmarketing |  |  |  | x |  |  |  | x | x | x | x | x | x |  | x | x | x | x |  | x | x | 
| Phototoxicity | postmarketing |  |  |  | x |  |  |  |  | x | x | x | x | x |  | x | x | x | x |  |  | x | 
| Skin hyperpigmentation | Skin hyperpigmentation | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Skin disorder | Unspecified disorder of skin and subcutaneous tissue | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Skin disorder |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Serum sickness-like reaction | Serum sickness-like reaction | very rare, postmarketing |  |  |  |  | x | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Malaise | Malaise | postmarketing, uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Ill-defined disorder | Malaise | postmarketing, uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Myalgia | Myalgia | postmarketing, rare |  |  |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Muscle twitching | Muscle twitching | postmarketing |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Abnormal dreams | Abnormal dreams | rare |  |  |  |  | x | x |  |  |  |  |  | x |  | x |  |  |  |  |  |  |  | 
| Eye irritation | Eye irritation | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Urethral haemorrhage | Urethral haemorrhage | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Punctate keratitis | Punctate keratitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Punctate epithelial erosion |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hepatobiliary disease | Hepatobiliary disease | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drug intolerance | Drug intolerance | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Epidermolysis | Epidermolysis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vision blurred | Vision blurred | postmarketing, uncommon |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Phobia | Phobia | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Platelet count decreased | Platelet count decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | x | x | 
| Candiduria | Candiduria | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Laboratory test abnormal | Laboratory test abnormal | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Chromatopsia | Chromatopsia | postmarketing |  |  |  | x |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Respiratory distress | Respiratory distress | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Lymphadenopathy | Lymphadenopathy | postmarketing |  |  |  | x |  |  | x |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Visual impairment | Visual disturbance | postmarketing — uncommon |  |  |  |  | x | x | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Abnormal vision |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Blood potassium increased | Serum potassium increased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Gait disturbance | Gait disturbance | very rare, postmarketing |  |  |  | x | x |  |  |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Prothrombin time shortened | Prothrombin time shortened | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Blood albumin decreased | Serum albumin decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Blood glucose decreased | Blood glucose decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Blood potassium decreased | Serum potassium decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hypercalcaemia | Serum calcium increased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Hypercalcaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Blood cholesterol increased | Cholesterol serum elevated | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Cardio-respiratory arrest | Cardio-respiratory arrest | postmarketing |  |  |  | x |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Thrombocytosis | Thrombocytosis | postmarketing, rare |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Allergic oedema | Allergic oedema | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypoaesthesia eye | Hypoaesthesia eye | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Corneal epithelium defect | Corneal epithelium defect | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Prothrombin level abnormal | Prothrombin level abnormal | rare |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Protein total decreased | Serum total protein decreased | postmarketing |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Monocyte count increased | Blood monocytes increased | postmarketing |  |  |  |  |  |  |  |  | x | x | x |  | x |  | x | x | x | x |  | x |  | 
| Acute generalised exanthematous pustulosis | Acute generalised exanthematous pustulosis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | x | 
| AGEP |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Insomnia | Insomnia | postmarketing |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Muscular weakness | Myasthenia | postmarketing |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Muscular weakness | very rare |  |  |  |  | x |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | x | 
| Aphasia | Dysphasia | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  |  | x | x | 
| Paranasal sinus hypersecretion | Paranasal sinus hypersecretion | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pseudomembranous colitis | Pseudomembranous colitis | postmarketing |  |  |  |  |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Ileus | Ileus | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  | x |  |  |  |  | x | x | x | 
| Ocular toxicity | Ocular toxicity | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Deafness | Hearing impaired | very rare — uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Hearing impaired | Hearing impaired | very rare — uncommon |  |  |  | x | x |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Paranoia | Paranoia | postmarketing |  |  |  |  |  |  | x | x |  |  |  | x |  |  |  |  |  |  | x | x | x | 
| Conjunctival hyperaemia | Conjunctival hyperaemia | rare |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ageusia | Ageusia | postmarketing |  |  |  |  |  | x | x |  | x | x | x | x | x |  | x | x | x | x | x | x | x | 
| Self injurious behaviour | Self injurious behaviour | very rare, rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | x | 
| Intentional self-injury | Self injurious behaviour | very rare, rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | x | 
| Suicidal ideation | Suicidal ideation | very rare, rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | x | 
| Completed suicide | Completed suicide | very rare, rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  | x | 
| Benign intracranial hypertension | Benign intracranial hypertension | very rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Intracranial pressure increased | Intracranial pressure increased | very rare, postmarketing |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Respiratory acidosis | Respiratory acidosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Alopecia | Alopecia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Asthma | Asthma |  |  |  |  |  | x |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Atrial fibrillation | Atrial fibrillation |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Back pain | Back pain |  |  |  |  | x |  | x |  | x | x | x | x |  | x | x | x | x | x | x |  | x | x | 
| Mental disorder | Mental disorder |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Coagulopathy | Coagulopathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Breast disorder | Breast disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Skin candida | Skin candida |  |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Oral candidiasis | Oral candidiasis |  |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Cerebrovascular disorder | Cerebrovascular disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Chest pain | Chest pain |  |  |  |  | x |  | x |  | x | x | x | x |  | x | x | x | x | x | x |  | x | x | 
| Retrosternal pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Colitis | Colitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Connective tissue disorder | Connective tissue disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Corneal opacity | Corneal opacity |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Cystitis | Cystitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Acute cystitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bladder infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bladder pain | Cystitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cystitis noninfective | Cystitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Depersonalisation | Depersonalisation |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | 
| Depression | Depression |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Fungal skin infection | Fungal skin infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Dysmenorrhoea | Dysmenorrhoea |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Dysuria | Dysuria |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  | 
| Oesophagitis | Oesophagitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Extravasation | Extravasation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye disorder | Eye disorder |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Fatigue | Fatigue |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Pain in extremity | Foot pain |  |  |  |  | x |  |  |  |  | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Leg pain |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Pain in arm |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Gastritis | Gastritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Gastrointestinal disorder | Gastrointestinal disorder |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Glossitis | Glossitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Cardiac arrest | Cardiac arrest |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hemiplegia | Hemiplegia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hepatomegaly | Hepatomegaly |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hyperbilirubinaemia | Hyperbilirubinaemia |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hypercholesterolaemia | Hypercholesterolaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hypernatraemia | Hypernatraemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hyperventilation | Hyperventilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hypocalcaemia | Hypocalcaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Kidney infection | Kidney infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Inflammation | Inflammation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Irritable bowel syndrome | Irritable bowel syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Functional gastrointestinal disorder | Irritable bowel syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Irritability | Irritability |  |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Renal failure acute | Renal failure acute |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Renal failure chronic | Renal failure chronic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Renal neoplasm | Renal neoplasm |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Laryngeal oedema | Laryngeal oedema |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Vaginal discharge | Leukorrhea |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hepatocellular injury | Liver disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hepatocellular injury |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Foetor hepaticus | Liver disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Breast pain | Breast pain |  |  |  |  | x |  |  |  |  | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Mediastinal disorder | Mediastinal disorder |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Megacolon | Megacolon toxic |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Melaena | Melaena |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Meningism | Meningism |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Metabolic disorder | Metabolic disorder |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Muscle spasticity | Muscle spasticity |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Necrosis | Necrosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Nervousness | Nervousness |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x |  | x | x | 
| Tension | Nervousness |  |  |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x |  | x | x | 
| Neuritis | Neuritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Blood urea increased | NPN increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nodule | Nodule |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Otitis externa | Otitis externa |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pericarditis | Pericarditis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Pharyngitis | Pharyngitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Prurigo | Prurigo |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pruritus genital | Pruritus genital |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Pulmonary oedema | Pulmonary oedema |  |  |  |  | x |  |  |  | x | x | x | x |  | x | x | x | x | x | x |  | x | x | 
| Repetitive strain injury | Repetitive strain injury |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Rhabdomyolysis | Rhabdomyolysis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sepsis | Septicemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Stridor | Stridor |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Swelling | Swelling |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Thirst | Thirst |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Thrombophlebitis | Thrombophlebitis |  |  |  |  |  |  | x |  | x |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Tooth discolouration | Tooth discolouration |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Typhoid fever | Typhoid fever |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Urinary incontinence | Urinary incontinence |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Urethral disorder | Urinary tract disorder |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Urinary tract disorder | Urinary tract disorder |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Angiopathy | Angiopathy |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vasodilation procedure | Vasodilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x | x | 
| Ventricular fibrillation | Ventricular fibrillation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ventricular tachycardia | Ventricular tachycardia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vaginitis bacterial | Vaginitis bacterial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Apathy | Apathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Flat affect | Apathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Rash pustular | Rash pustular |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Vesiculobullous rash |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Oedema peripheral | Oedema peripheral |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hepatic function abnormal | Hepatic function abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Creatinine renal clearance decreased | Creatinine renal clearance decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood creatinine increased | Creatinine increased |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Deafness transitory | Deafness transitory |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Tongue discolouration | Tongue discolouration |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Tongue disorder | Tongue oedema |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Tongue oedema | Tongue oedema |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Electrolyte imbalance | Electrolyte abnormality |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Blood electrolytes abnormal | Electrolyte abnormality |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Gamma-glutamyltransferase increased | Gamma-glutamyltransferase increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Impaired healing | Impaired healing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Pulmonary haemorrhage | Pulmonary haemorrhage |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Injection site reaction | Injection site reaction |  |  |  |  | x |  | x |  |  | x |  |  |  | x |  | x | x | x | x |  | x |  | 
| Injury | Accidental injury |  |  |  |  |  |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Blood lactate dehydrogenase increased | Lactic dehydrogenase activity increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Liver injury | Hepatocellular injury |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bone pain | Bone pain |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Blood alkaline phosphatase increased | Phosphatase alkaline increased |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Prothrombin level increased | Prothrombin level increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dry skin | Dry skin |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Renal vasculitis | Renal vasculitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Joint swelling | Joint swelling |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  | 
| Malnutrition | Malnutrition |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Scab | Scab |  |  |  | x |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Disability | Disability |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Increased appetite | Increased appetite |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Abdominal discomfort | Abdominal discomfort |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Abdominal pain upper | Epigastric pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Abdominal pain lower | Abdominal pain lower |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Suprapubic pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Proctalgia | Rectal tenesmus |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Rectal tenesmus | Rectal tenesmus |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Anorectal discomfort | Rectal tenesmus |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Disturbance in attention | Disturbance in attention |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Tenderness | Tenderness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Swollen tongue | Swollen tongue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Blood creatinine decreased | Creatinine low |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Suprapubic pain | Suprapubic pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Colour blindness | Colour blindness |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Extrasystoles | Ventricular bigeminy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Urine odour abnormal | Urine odour abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Papule | Papule |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Anaphylactoid reaction | Anaphylactoid reaction |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Gastrointestinal candidiasis | Gastrointestinal candidiasis |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Abdominal distension | Enlargement abdomen |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Rash maculo-papular | Rash maculo-papular |  |  |  |  |  |  | x | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Aortic bruit | Abdominal aortic bruit |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Bradycardia | Bradycardia |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Ligament sprain | Joint sprain |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Transaminases increased | Transaminases increased |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dementia | Dementia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Coordination abnormal | Coordination abnormal |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Application site pain | Application site pain |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Instillation site pain | Application site pain |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Face oedema | Face oedema |  |  |  |  | x |  |  |  |  | x | x | x |  | x |  | x | x | x | x |  | x |  | 
| Surgery | Surgical intervention |  |  |  |  | x |  |  |  |  |  | x | x |  | x |  | x | x | x | x |  | x | x | 
| Lipase increased | Lipase increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Prothrombin level decreased | Prothrombin level decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cough | Cough increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Nephropathy toxic | Nephropathy toxic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Menopausal symptoms | Hot flush |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Hot flush | Hot flush |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Drug interaction | Drug interaction |  |  |  |  | x |  |  |  | x | x | x | x |  | x |  | x | x | x | x |  | x | x | 
| Hyperuricaemia | Hyperuricaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Ear pruritus | Ear pruritus |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Infestation | Infestation NOS |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Skin haemorrhage | Skin haemorrhage |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| International normalised ratio decreased | International normalised ratio decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Chromosomal mutation | Chromosomal mutation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pneumonia | Nosocomial pneumonia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Medication residue present | Medication residue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Parosmia | Parosmia |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pathogen resistance | Cross resistance |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |