Definition: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Synonyms (terms occurring on more labels are shown first): chronic renal failure, end-stage renal disease, end stage renal disease, ESRD, end-stage renal failure, end stage renal failure, renal failure chronic, ESRF, end- stage renal failure, end- stage renal disease
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