Search results :

Rofecoxib

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: M01AH02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5
Upper respiratory tract infection Upper respiratory tract infection 5.8% - 8.5% 7.8% x x x x x
Diarrhoea Diarrhoea 6.5% - 10.6% 6.8% x x x x x
Nausea Nausea 5.2% - 7.4% 2.9% x x x x x
Headache Headache 4.7% - 8% 7.5% x x x x x
Epigastric discomfort Epigastric discomfort 2.8% - 9.2% 2.8% x x x x x
Abdominal pain Abdominal pain 3.4% - 5.8% 4.1% x x x x x
Gastrointestinal pain Abdominal pain 3.4% - 5.8% 4.1% x x x x x
Dyspepsia Heartburn 3.6% - 5.2% 3.6% x x x x x
Dyspepsia 2.7% - 4.7% 2.7% x x x x x
Oedema peripheral Edema of lower extremities 1.1% - 6.3% 1.1% x x x x x
Oedema peripheral x x x x x
Upper limb oedema x x x x x
Dizziness Dizziness 2.2% - 3.4% 2.2% x x x x x
Syncope x x x x x
Hypertension Hypertension 1.6% - 8.2% 1.3% x x x x x
Influenza Influenza 1.5% - 3.2% 3.1% x x x x x
Urinary tract infection Urinary tract infection 2.5% - 3.6% 2.7% x x x x x
Back pain Back pain 1.4% - 2.8% 1.9% x x x x x
Sinusitis Sinusitis 1.8% - 2.7% 2% x x x x x
Asthenia Asthenia 1% - 2.6% 1% x x x x x
Fatigue 1% - 2.6% 1% x x x x x
Fatigue Fatigue 1% - 2.6% 1% x x x x x
Bronchitis Bronchitis 0.8% - 3.2% 0.8% x x x x x
Abdominal distension Abdominal distension x x x x x
Congenital anomaly Congenital anomaly x
Developmental delay Congenital anomaly x
Abscess Abscess x x x x x
Agranulocytosis Agranulocytosis x x x x
Alopecia Alopecia x x x x x
Aplastic anaemia Aplastic anaemia x x x
Angina pectoris Angina pectoris x x x x x
Angina unstable x x x x x
Angina unstable Angina unstable x x x x x
Angioedema Angioedema x x x x
Anxiety Anxiety x x x x x
Arthralgia Arthralgia x x x x x
Musculoskeletal discomfort Arthralgia x x x x x
Myalgia x x x x x
Asthma Asthma x x x x x
Atrial fibrillation Atrial fibrillation x x x x x
Mental disorder Mental disorder x
Blister Blister x x x x x
Dermatitis bullous Blister x x x x x
Breast cancer Breast cancer x x x x x
Bronchospasm Bronchospasm x x x x
Bursitis Bursitis x x x x x
Neoplasm malignant Neoplasm malignant x x x x x
Basal cell carcinoma Basal cell carcinoma x x x x x
Cellulitis Cellulitis x x x x x
Transient ischaemic attack Transient ischaemic attack x x x x x
Chest pain Chest pain x x x x x
Cholecystitis Cholecystitis x x x x x
Colitis Colitis x x x x x
Infection Infection x x x x x
Confusional state Confusional state x x x x
Feeling abnormal Confusional state x x x x
Conjunctivitis Conjunctivitis x x x x x
Constipation Constipation x x x x x
Contusion Contusion x x x x x
Cough Cough x x x x x
Cystitis Cystitis x x x x x
Bladder pain Cystitis x x x x x
Cystitis noninfective Cystitis x x x x x
Dental caries Dental caries x x x x x
Dermatitis atopic Dermatitis atopic x x x x x
Dermatitis contact Dermatitis contact x x x x x
Alveolar osteitis Alveolar osteitis x x x x x
Duodenal ulcer Duodenal ulcer x x x x x
Dysgeusia Dysgeusia x x x x x
Dyspnoea Dyspnoea x x x x x
Dysuria Dysuria x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis x x x x
Epistaxis Epistaxis x x x x x
Oesophagitis Oesophagitis x x x x x
Dermatitis Rash x x x x x
Rash Rash x x x x x
Body temperature increased Body temperature increased x x x x x
Flatulence Flatulence x x x x x
Flushing Flushing x x x x x
Gastritis Gastritis x x x x x
Gastroenteritis Gastroenteritis x x x x x
Gastric flu x x x x x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease x x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x x x x
Hallucination Hallucination x x x x
Cardiac failure congestive Cardiac failure congestive x x x x x
Haematochezia Haematochezia x x x x x
Haematoma Haematoma x x x x x
Haemorrhoids Haemorrhoids x x x x x
Hepatitis Hepatitis x x x x
Diaphragmatic hernia Diaphragmatic hernia x x x x x
Herpes simplex Herpes simplex x x x x x
Herpes zoster Herpes zoster x x x x x
Hypercholesterolaemia Hypercholesterolaemia x x x x x
Hyperkalaemia Hyperkalaemia x x x x
Hypersensitivity Hypersensitivity x x x x x
Hypertensive crisis Hypertensive crisis x x x
Hypoaesthesia Hypoaesthesia x x x x x
Hyponatraemia Hyponatraemia x x x x
Cerumen impaction Cerumen impaction x x x x x
Infarction Infarction x
Arthropod bite Insect bite NOS x x x x x
Intestinal obstruction Intestinal obstruction x x x x x
Jaundice Jaundice x x x x
Renal failure acute Renal failure acute x x x x
Renal failure chronic Renal failure chronic x x x x
Laryngitis Laryngitis x x x x x
Leukopenia Leukopenia x x x x
Breast mass Breast mass x x x x x
Lymphoma Lymphoma x x x x x
Non-Hodgkin's lymphoma Lymphoma x x x x x
Meningitis aseptic Meningitis aseptic x x x x
Menstrual disorder Menstrual disorder x x x x x
Muscle spasms Cramp muscle x x x x x
Muscle spasms x x x x x
Myopathy Myopathy x x x x x
Musculoskeletal pain Musculoskeletal pain x x x x x
Fungal infection Fungal infection x x x x x
Myocardial infarction Myocardial infarction x x x x
Acute coronary syndrome Myocardial infarction x x x x
Nasal congestion Nasal congestion x x x x x
Nasopharyngitis Nasopharyngitis x
Tubulointerstitial nephritis Nephritis interstitial x x x x
Nocturia Nocturia x x x x x
Ear infection Otitis x x x x x
Otitis media Otitis media x x x x x
Procedural pain Postoperative pain x x x x x
Palpitations Palpitations x x x x x
Pancreatitis Pancreatitis x x x x x
Pancytopenia Pancytopenia x x x
Paraesthesia Paraesthesia x x x x x
Pelvic pain Pelvic pain x x x x x
Pharyngitis Pharyngitis x x x x x
Pneumonia Pneumonia x x x x x
Pruritus Pruritus x x x x x
Pulmonary oedema Pulmonary oedema x x x x
Pulmonary embolism Pulmonary embolism x x x x x
Respiratory tract infection Respiratory tract infection x x x x x
Rhinitis Rhinitis x
Sciatica Sciatica x x x x x
Erythema multiforme Stevens-Johnson syndrome x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome x x x x
Gastric disorder Gastric disorder x x x x x
Gastric ulcer Gastric ulcer x x x x
Aphthous stomatitis Aphthous stomatitis x x x x x
Cerebrovascular accident Cerebrovascular accident x x x x x
Shock Syncope x x x x x
Syncope Syncope x x x x x
Loss of consciousness Syncope x x x x x
Tachycardia Tachycardia x x x x x
Tendonitis Tendonitis x x x x x
Thrombocytopenia Thrombocytopenia x x x x
Tinnitus Tinnitus x x x x x
Tonsillitis Tonsillitis x x x x x
Toothache Toothache x x x x x
Erythema Erythema x x x x x
Urticaria Urticaria x x x x x
Vaginal inflammation Vaginal inflammation x x x x x
Vaginal infection Vaginal inflammation x x x x x
Venous insufficiency Venous insufficiency x x x x x
Vertigo Vertigo x x x x x
Viral infection Viral syndrome x x x x x
Vomiting Vomiting x x x x x
Weight increased Weight increased x x x x x
Laceration Laceration x x x x x
Injury Trauma x x x x x
Dry mouth Dry mouth x x x x x
Urinary retention Urinary retention x x x x x
Chills Chills x x x x x
Hepatic failure Hepatic failure x x x x
Oral disorder Oral lesion x x x x x
Stomatitis Mouth ulceration x x x x x
Mouth ulceration Mouth ulceration x x x x x
Deep vein thrombosis Deep vein thrombosis x x x x x
Leukocytoclastic vasculitis Allergic cutaneous angiitis x x x x
Ventricular extrasystoles Ventricular extrasystoles x x x x x
Muscular weakness Muscular weakness x x x x x
Oesophageal ulcer Oesophageal ulcer x x x x
Joint swelling Joint swelling x x x x x
Traumatic arthropathy Traumatic arthropathy x x x x x
Ligament sprain Ankle sprain x x x x x
Photosensitivity reaction Photosensitivity reaction x
Disability Disability x
Myalgia Myalgia x x x x x
Abdominal pain upper Abdominal pain upper x
Epigastric pain x x x x
Abdominal tenderness Abdominal tenderness x x x x x
Dry throat Dry throat x x x x x
Gastric perforation Gastric perforation x x x x
Menopausal symptoms Menopausal symptoms x x x x x
Heart rate irregular Heart rate irregular x x x x x
Pain in extremity Pain in arm x x x x x
Pulmonary congestion Pulmonary congestion x x x x x
Respiratory tract congestion Pulmonary congestion x x x x x
Xerosis Xerosis x x x x x
Duodenal perforation Duodenal perforation x x x x
Fluid retention Fluid retention x x x x x
Viral diarrhoea Gastric flu x x x x x
Anaphylactic shock Anaphylactoid reaction x x x x
Anaphylactoid reaction Anaphylactoid reaction x x x x
Vision blurred Vision blurred x x x x x
Muscle strain Back strain x x x x x
Gastrointestinal disorder Gastrointestinal symptom NOS x x x x
Bradycardia Bradycardia x x x x x
Wrist fracture Wrist fracture x x x x x
Neuropathy peripheral Neuropathy x x x x x
Calculus urinary Urolithiasis x x x x x
Pseudoporphyria Pseudoporphyria x
Alveolitis Alveolitis x x x x x
Oral infection Oral infection x x x x x
Epilepsy Epilepsy aggravated x x x
Insomnia Insomnia x x x x x
Musculoskeletal stiffness Musculoskeletal stiffness x x x x x
Excoriation Abrasion NOS x x x x x
Rhinitis allergic Rhinitis allergic x x x x x
Somnolence Somnolence x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

ROFECOXIB / VIOXX

Side effects:157
Source:FDA

rofecoxib / Vioxx

Side effects:183
Source:FDA

rofecoxib / Vioxx

Side effects:183
Source:FDA

rofecoxib / Vioxx

Side effects:185
Source:FDA

ROFECOXIB / VIOXX

Side effects:190
Source:FDA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label