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Hydrochlorothiazide

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: C03AA03

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Upper respiratory tract infection Upper respiratory tract infection 6.1% 4.6% x
Dizziness Dizziness 5.7% 2.9% x x x x x x x x x x x x x x x x x x
Syncope x
Cough Cough 2.6% 2.3% x
Dry cough x
Persistent dry cough x
Back pain Back pain 2.1% 0.6% x
Dermatitis Rash 1.4% 0% x x x x x x x x x x x x x x x x x x
Dermatitis x
Rash Rash 1.4% 0% x x x x x x x x x x x x x x x x x x
Palpitations Palpitations 1.4% 0% x
Oedema Oedema 1.3% 1.2% x
Swelling Swelling 1.3% 1.2% x
Abdominal pain Abdominal pain 1.2% 0.6% x
Gastrointestinal pain Abdominal pain 1.2% 0.6% x
Sinusitis Sinusitis 1.2% 0.6% x
Agranulocytosis Agranulocytosis x x x x x x x x x x x x x x x x x x
Obstructive airways disorder Airway obstruction NOS x
Alopecia Alopecia x x x x x x x x x x x x x x x x x
Anaphylactic shock Anaphylactic shock x x x x x x x x x x x x x x x x x
Anaemia Anaemia x x
Aplastic anaemia Aplastic anaemia x x x x x x x x x x x x x x x x x
Haemolytic anaemia Haemolytic anaemia x x x x x x x x x x x x x x x x x
Angina pectoris Angina pectoris x
Angioedema Angioedema x
Decreased appetite Anorexia x x x x x x x x x x x x x x x x x x
Anxiety Anxiety x
Anxiety disorder Anxiety disorder x
Arrhythmia Arrhythmia x
Arthralgia Arthralgia x
Coxalgia x
Knee pain x
Musculoskeletal discomfort Arthralgia x
Myalgia x
Arthritis Arthritis x
Asthenia Asthenia x x x x x x x x x x x x x x x x x
Ataxia Ataxia x
Atrial fibrillation Atrial fibrillation x
Chest pain Chest pain x
Confusional state Confusional state x
Feeling abnormal Confusional state x
Malaise x
Conjunctivitis Conjunctivitis x
Constipation Constipation x x x x x x x x x x x x x x x x x x
Libido decreased Libido decreased x
Disturbance in sexual arousal Libido decreased x
Dermatitis exfoliative Dermatitis exfoliative x x x x x x x x x x x x x x x x x
Diarrhoea Diarrhoea x x x x x x x x x x x x x x x x x
Dysgeusia Dysgeusia x
Dyspepsia Dyspepsia x
Dyspnoea Dyspnoea x
Ecchymosis Ecchymosis x
Toxic epidermal necrolysis Toxic epidermal necrolysis x x x x x x x x x x x x x x x x x
Epistaxis Epistaxis x
Erythema multiforme Erythema multiforme x x x x x x x x x x
Stevens-Johnson syndrome x x x x x x x x x x x x x x x x x
Body temperature increased Body temperature increased x x x x x x x x x x x x x x x x x x
Fibromyalgia Fibromyalgia x
Flatulence Flatulence x
Flushing Flushing x
Gastritis Gastritis x
Glycosuria Glycosuria x x x x x x x x x x x x x x x x x x
Gout Gout x
Headache Headache x x x x x x x x x x x x x x x x x
Hepatitis Hepatitis x
Hyperglycaemia Hyperglycaemia x x x x x x x x x x x x x x x x x x
Hyperkalaemia Hyperkalaemia x
Hypersensitivity Hypersensitivity x x x x x x x x x x x x x x x x
Hypoaesthesia Hypoaesthesia x
Hyponatraemia Hyponatraemia x
Hypotension Hypotension x x x x x x x x x x x x x x x x
Orthostatic hypotension Orthostatic hypotension x x x x x x x x x x x x x x x x x
Jaundice Jaundice x x x x x x x x x x x x x x x x x x
Jaundice cholestatic Jaundice cholestatic x x x x x x x x x x x x x x x x x x
Pain in extremity Leg pain x
Pain in arm x
Leukopenia Leukopenia x x x x x x x x x x x x x x x x x x
Muscle spasms Cramp muscle x x x x x x x x x x x x x x x x x x
Muscle spasms x x x x x x x x x x x x x x x x x x
Musculoskeletal pain Musculoskeletal pain x
Shoulder pain x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Nasal congestion Nasal congestion x
Nausea Nausea x x x x x x x x x x x x x x x x x
Tubulointerstitial nephritis Nephritis interstitial x x x x x x x x x x x x x x x x x
Nervousness Nervousness x
Tension Nervousness x
Nocturia Nocturia x
Pancreatitis Pancreatitis x x x x x x x x x x x x x x x x
Panic disorder Panic disorder x
Sinus disorder Sinus disorder x
Paraesthesia Paraesthesia x x x x x x x x x x x x x x x x x x
Neuropathy peripheral Neuropathy peripheral x
Pneumonia Pneumonia x x x x x x x x x x x x x x x x x x
Pruritus Pruritus x
Pulmonary oedema Pulmonary oedema x x x x x x x x x x x x x x x x x
Purpura Purpura x x x x x x x x x x x x x x x x x x
Vascular purpura Purpura x x x x x x x x x x x x x x x x x x
Henoch-Schonlein purpura Henoch-Schonlein purpura x
Renal failure Renal failure x x x x x x x x x x x x x x x x
Rhabdomyolysis Rhabdomyolysis x
Rhinitis Rhinitis x
Sialoadenitis Sialoadenitis x x x x x x x x x x x x x x x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome x x x x x x x x x x x x x x x x x
Hyperhidrosis Sweating x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Tachycardia Tachycardia x
Thrombocytopenia Thrombocytopenia x x x x x x x x x x x x x x x x x x
Tinnitus Tinnitus x
Toothache Toothache x
Tremor Tremor x
Erythema Erythema x x x x x x x x
Pollakiuria Pollakiuria x
Urinary tract infection Urinary tract infection x
Urticaria Urticaria x x x x x x x x x x x x x x x x x x
Vasculitis Vasculitis x x x x x x x x x x x x x x x x x x
Ventricular fibrillation Ventricular fibrillation x
Ventricular tachycardia Ventricular tachycardia x
Vertigo Vertigo x x x x x x x x x x x x x x x x x
Vomiting Vomiting x x x x x x x x x x x x x x x x x x
Dry mouth Dry mouth x
Sinus bradycardia Sinus bradycardia x
Agitation Agitation x x x x x x x x x x x x x x x x x x
Migraine Migraine x
Blood urea increased Blood urea increased x
Muscular weakness Muscular weakness x
Dry skin Dry skin x
Joint swelling Joint swelling x
Xanthopsia Xanthopsia x x x x x x x x x x x x x x x x x
Malaise Malaise x
Discomfort Malaise x
Discomfort x
Ill-defined disorder Malaise x
Myalgia Myalgia x
Memory impairment Memory impairment x
Erectile dysfunction Erectile dysfunction x x x x x x x x x x x x x x x
Cutaneous vasculitis Cutaneous vasculitis x x x x x x x x x x x x x x x x x
Atrioventricular block second degree Atrioventricular block second degree x
Electrolyte imbalance Electrolyte imbalance x x x x x x x x x x x x x x x
Vision blurred Vision blurred x x x x x x x x x x x x x x x x x
Photosensitivity reaction Photosensitivity x x x x x x x x x x x x x x x x x x
Epigastric discomfort Gastric irritation x x x x x x x x x x x x x x x x x x
Musculoskeletal stiffness Stiffness x
Respiratory distress Respiratory distress x x x x x x x x x x x x x x x x x x
Face oedema Face oedema x
Vasculitis necrotising Angiitis necrotising x x x x x x x x x x x x x x x x x x
Pain Stinging x
Blood creatinine increased Serum creatinine increased x
Blood uric acid increased Hyperuricaemia x x x x x x x x x x x x x x x x x x
Hyperuricaemia Hyperuricaemia x x x x x x x x x x x x x x x x x x
Sleep disorder Sleep disorder x
Insomnia Insomnia x
Somnolence Somnolence x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

HYDROCHLOROTHIAZIDE / PMS-HYDROCHLOROTHIAZIDE

Side effects:39
Source:Health Canada

HYDROCHLOROTHIAZIDE

Side effects:43
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:50
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:51
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:51
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:51
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

hydrochlorothiazide

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:52
Source:FDA Structured Product Label

Hydrochlorothiazide

Side effects:52
Source:FDA Structured Product Label

HYDROCHLOROTHIAZIDE

Side effects:134
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label