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Cisplatin

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XA01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Nephropathy toxic Nephrotoxicity 28-36% x x x x x
Nephropathy toxic x x x x x
Ototoxicity Ototoxicity 31% x x x x x
Vestibular toxicity x x x x
Pancytopenia Myelosuppression 25-30% x x x x x
Tinnitus Tinnitus 9% x x x x x x
Alopecia Alopecia x x x
Anaphylactic shock Anaphylactic shock x
Anaphylactoid reaction x
Anaemia Anaemia x x x x x x
Secondary anemia x x x
Haemolytic anaemia Haemolytic anaemia x x x x
Decreased appetite Anorexia x x x x
Arrhythmia Arrhythmia x x
Asthenia Asthenia x x x
Azoospermia Azoospermia x
Breast disorder Breast disorder x
Cellulitis Cellulitis x x
Cerebral arteritis Cerebral arteritis x x
Clonus Clonus x x x
Infection Infection x x x
Conjunctivitis Conjunctivitis x
Connective tissue disorder Connective tissue disorder x
Coronary artery disease Coronary heart disease x
Deafness Deafness x x x x
High frequency deafness x
Hearing impaired x x x x x
Dehydration Dehydration x
Diarrhoea Diarrhoea x x x x
Polyuria Diuresis x x x
Dyspnoea Dyspnoea x
Oedema Oedema x x x
Electric shock Electric shock x
Dermatitis Rash x x x
Rash Rash x x x
Extravasation Extravasation x x x x
Eye disorder Eye disorder x
Body temperature increased Body temperature increased x x x x
Fibrosis Fibrosis x
Flushing Flushing x x
Gastrointestinal disorder Gastrointestinal disorder x
Heart disease congenital Heart malformation x x
Cardiac disorder Cardiac disorder x
Cardiac failure congestive Cardiac failure congestive x
Haemolysis Haemolysis x
Haemolytic uraemic syndrome Haemolytic uraemic syndrome x
Hiccups Hiccups x x
Hypersensitivity Hypersensitivity x
Hypokalaemia Hypokalaemia x x x
Hyponatraemia Hyponatraemia x x x
Hypotension Hypotension x x x x
Orthostatic hypotension Orthostatic hypotension x
Immune system disorder Immune system disorder x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion x
Irritability Irritability x x x
Renal failure acute Renal failure acute x x x
Leukopenia Leukopenia x x x x x
Mediastinal disorder Mediastinal disorder x
Muscle spasms Cramp muscle x x x x
Myocardial infarction Myocardial infarction x x
Acute coronary syndrome Myocardial infarction x x
Nasal congestion Nasal congestion x
Nausea Nausea x x x x x x
Necrosis Necrosis x
Nervous system disorder Nervous system disorder x
Optic neuritis Optic neuritis x x x
Papilloedema x x x
Pain Pain x
Pancreatitis Pancreatitis x
Papilloedema Papilloedema x x x
Paraesthesia Paraesthesia x
Neuropathy peripheral Neuropathy peripheral x x x x
Neuropathy x x x
Phlebitis Phlebitis x
Renal failure Renal failure x
Convulsion Convulsion x x x
Spinal cord disorder Spinal cord disorder x x
Stomatitis Stomatitis x
Cerebrovascular accident Cerebrovascular accident x x x
Tachycardia Tachycardia x x x x
Tetany Tetany x x x x
Carpo-pedal spasm x x x
Thrombocytopenia Thrombocytopenia x x x x x
Tremor Tremor x x x
Erythema Erythema x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Vomiting Vomiting x x x x x x
Wheezing Wheezing x x x x
Acute leukaemia Acute leukaemia x x x x x
Hypophosphataemia Hypophosphataemia x x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Renal tubular disorder Renal tubular disorder x
Hepatocellular injury Hepatocellular injury x
Liver injury Hepatocellular injury x
Skin necrosis Skin necrosis x
Skin exfoliation Skin necrosis x
Retinal pigmentation Retinal pigmentation x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Blindness cortical Blindness cortical x
Malnutrition Malnutrition x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Malaise Malaise x
Discomfort Malaise x
Feeling abnormal Malaise x
Ill-defined disorder Malaise x
Myalgia Myalgia x
Musculoskeletal discomfort Myalgia x
Anxiety Apprehension x
Areflexia Areflexia x
Dysarthria Slurred speech x
Neurological symptom Neurological symptom x
Neurotoxicity Neurotoxicity x x x
Hepatotoxicity Hepatotoxicity x
Autonomic neuropathy Autonomic neuropathy x x x
Hepatobiliary disease Hepatobiliary disease x
Leukoencephalopathy Leukoencephalopathy x
Glucose tolerance impaired Glucose tolerance impaired x
Anaphylactoid reaction Anaphylactoid reaction x
Vision blurred Vision blurred x x x
Bradycardia Bradycardia x
Blindness Blindness x x
Amylase increased Serum amylase increased x x
Face oedema Face oedema x x
Lhermitte's sign Lhermitte's sign x x
Blood creatinine increased Serum creatinine increased x
Hyperhidrosis Sweating increased x
Blood uric acid increased Hyperuricaemia x x x x
Hyperuricaemia Hyperuricaemia x x x x
Febrile neutropenia Febrile neutropenia x
Amnesia Memory loss x
Generalised erythema Generalised erythema x
Renal failure chronic Irreversible renal failure x
Retinal toxicity Retinal toxicity x
Pulmonary toxicity Pulmonary toxicity x
Bone marrow toxicity Bone marrow toxicity x
Loss of proprioception Loss of proprioception x
Nasopharyngitis Rhinorrhoea x
Rhinorrhoea Rhinorrhoea x
Ocular toxicity Ocular toxicity x
Urine output Urine output x
Hearing impaired Hearing impaired x x x x x
Ageusia Ageusia x x x
Thrombotic microangiopathy Thrombotic microangiopathy x x x
Metastatic neoplasm Metastatic neoplasm x
Posterior reversible encephalopathy syndrome Posterior reversible encephalopathy syndrome x
Visual impairment Visual impairment x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

CISPLATIN

Side effects:21
Source:FDA Structured Product Label

cisplatin

Side effects:21
Source:FDA Structured Product Label

CISPLATIN

Side effects:69
Source:FDA Structured Product Label

Cisplatin

Side effects:72
Source:BC Cancer

Cisplatin

Side effects:76
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label