Leukoencephalopathy
Definition: White matter changes first described in children with leukemia, associated with radiation and chemotherapy injury, often associated with methotrexate; pathologically characterised by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. (On-line Medical Dictionary)
Synonyms (terms occurring on more labels are shown first): leukoencephalopathy, leukoencephalo- pathy
More information: PubMed search and possibly Wikipedia
Drugs with this side effect as MedDRA Preferred Term
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