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Definition: White matter changes first described in children with leukemia, associated with radiation and chemotherapy injury, often associated with methotrexate; pathologically characterised by diffuse reactive astrocytosis with multiple areas of necrotic foci without inflammation. (On-line Medical Dictionary)

Synonyms (terms occurring on more labels are shown first): leukoencephalopathy, leukoencephalo- pathy

More information: PubMed search and possibly Wikipedia

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