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Cytarabine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01BC01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14
Conjunctivitis Conjunctivitis 80% x x x x x x x x
Arachnoiditis Arachnoiditis 16% - 42.4% x x x x x x x
Headache Headache 2% - 56.4% x x x x x x x x x x x x x x
Asthenia Fatigue 6% - 46.4% x x x x
Asthenia 5% - 53.6% x x x x x x
Fatigue Fatigue 6% - 46.4% x x x x
Body temperature increased Body temperature increased 0% - 45.5% x x x x x x x x x x x x x x
Gait disturbance Gait disturbance 1% - 29% x x x x x x
Dizziness Dizziness 18% - 21.4% x x x x x x x x x x x
Syncope 0% - 11% x x x
Diarrhoea Diarrhoea 11% - 32.1% x x x x x x x x x x x x
Insomnia Insomnia 13.6% - 25% x x x
Nausea Nausea 0% - 53.6% x x x x x x x x x x x x x x
Vomiting Vomiting 2% - 43.6% x x x x x x x x x x x x x x
Urinary tract infection Urinary tract infection 13.6% - 18.2% x x x
Pain in extremity Pain in extremity 12.1% - 28.6% x x x
Tremor Tremor 8.56% - 18% x x x x
Back pain Back pain 0% - 23.7% x x x x x x x
Abdominal pain Abdominal pain 8.56% - 15.2% x x x x x x x x x x x
Gastrointestinal pain Abdominal pain 8.56% - 15.2% x x x x x x x x x x x
Depression Depression 8.17% - 18.2% x x x
Lethargy Lethargy 12.1% - 16% x x x
Convulsion Convulsion 1% - 22% x x x x x x x
Dehydration Dehydration 10.7% - 18.2% x x x
Neck pain Neck pain 4% - 15.2% x x x x x x
Dyspnoea Dyspnoea 9.73% - 21.4% x x x x x x x x x x x
Anaemia Anaemia 1% - 18.2% x x x x x x x x x x x x x
Memory impairment Memory impairment 3.57% - 14% x x x
Arthralgia Arthralgia 9.09% - 14.3% x x x
Musculoskeletal discomfort Arthralgia 9.09% - 14.3% x x x
Myalgia x x x x x x x x
Decreased appetite Decreased appetite 10.7% - 12.1% x x x
Anorexia 3.03% - 17.9% x x x x x x x x x x x
Vision blurred Vision blurred 11% - 14.3% x x x x x
Confusional state Confusional state 2% - 36.4% x x x x x x x
Feeling abnormal Confusional state 2% - 36.4% x x x x x x x
Malaise x x x x x x x x
Constipation Constipation 0% - 25% x x x x x
Neutropenia Neutropenia 8% - 36.4% x x x x x x
Thrombocytopenia Thrombocytopenia 5% - 32.1% x x x x x x x x x x x x x x
Hypoaesthesia Hypoaesthesia 2% - 12.1% x x x x x x
Numbness 3% x
Hypoalgesia x
Deafness Hearing impaired 5.84% - 18.2% x x x
Deafness 3% x
Hearing impaired Hearing impaired 5.84% - 18.2% x x x
Oedema peripheral Oedema peripheral 0% - 25% x x x x x
Agitation Agitation 7.14% - 15.2% x x x
Pain Pain 0% - 20% x x x x x x x x
Muscular weakness Muscular weakness 7.14% - 15.2% x x x x
Cough Cough 6.61% - 21.4% x x x x
Dysphagia Dysphagia 7.78% - 10.7% x x x
Incontinence Incontinence 7.39% - 17.9% x x x x
Neuropathy peripheral Neuropathy 2.72% - 11% x x x x x x x x x x x
Neuropathy peripheral 3.5% - 12.1% x x x x
Neuritis x x x x x x x
Neurotoxicity Neurotoxicity 8-10% x x x x
CNS toxicity x
Tachycardia Tachycardia 0% - 17.9% x x x
Musculoskeletal stiffness Neck stiffness 1.28% - 14.3% x x x x x x x
Nuchal rigidity Neck stiffness 1.28% - 14.3% x x x x x x x
Hypotension Hypotension 7.14% - 18.2% x x x
Hyperglycaemia Hyperglycaemia 5.84% - 12.1% x x x
Hypokalaemia Hypokalaemia 6.61% - 15.2% x x x x
Mucosal inflammation Mucosal inflammation 3.11% - 12.1% x x x x
Hyponatraemia Hyponatraemia 3.57% - 12.1% x x x
Anxiety Anxiety 3.03% - 10.7% x x x
Pneumonia Pneumonia 6.06% - 10.7% x x x x x x x x x x x
Peripheral sensory neuropathy Peripheral sensory neuropathy 2.72% - 11% x x x
Hypertension Hypertension 3.57% - 15.2% x x x
Urinary retention Urinary retention 0% - 10.7% x x x x x x x x x x x
Somnolence Somnolence 2% - 12% x x x x x x x x x x x
Haemorrhoids Haemorrhoids 0% - 10.7% x x x
Platelet count decreased Platelet count decreased 0% - 10.7% x x x
Shock Syncope 0% - 11% x x x
Syncope Syncope 0% - 11% x x x
Loss of consciousness Syncope 0% - 11% x x x
Contusion Contusion 2.33% - 10.7% x x x
Oedema Oedema 2.33% - 21.4% x x x
Diffuse large B-cell lymphoma Diffuse large B-cell lymphoma 0.389% - 10.7% x x x
Hyperhidrosis Sweating increased 2.33% - 10.7% x x x
Sensory loss Numbness 3% x
Paraesthesia Paraesthesia 3% x x
Spinal cord disorder Spinal cord disorder 3% x
Cranial nerve paralysis Cranial nerve paralysis 3% x
Cauda equina syndrome Cauda equina syndrome 3% x
Reflexes abnormal Reflexes abnormal 0% - 11% x x x
Pruritus Pruritus 0% - 14.3% x x x x x x x x x x x
Hydrocephalus Hydrocephalus 2% x
Hydrocephalus acquired x x x
Urinary incontinence Urinary incontinence 0% - 11% x x x
Hemiplegia Hemiplegia 1% x
Altered state of consciousness Altered state of consciousness 1% x
Blindness Blindness 1% x x x x
Meningism Meningism 1% x x x x x x x
Cardio-respiratory arrest Cardio-respiratory arrest 1% x x
Alopecia Alopecia x x x x x x x x
Anaphylactic shock Anaphylactic shock x x x x x x x x
Anaemia megaloblastic Anaemia megaloblastic x
Mental disorder Mental disorder x x x x
Cellulitis Cellulitis x x x x x x
Cerebellar syndrome Cerebellar syndrome x x x x x x x x
Nervous system disorder Cerebellar syndrome x x x x x x x x
Nervous system disorder x x x x x x x x x x x
Cerebral dysfunction x
Neurological impairment x
Chest pain Chest pain x x x x x x x x
Coma Coma x x x x x x x
Infection Infection x x x x x x x x x x x
Connective tissue disorder Connective tissue disorder x x x x
Cyst Cyst x x x
Oesophagitis Oesophagitis x x x x x x x x
Dermatitis Rash x x x x x x x x
Rash Rash x x x x x x x x
Extravasation Extravasation x
Eye disorder Eye disorder x x x x x
Ephelides Ephelides x x x x x x x x
Solar lentigo Ephelides x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder x x x x x
Unspecified disorder of intestine x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Guillain-Barre syndrome Guillain-Barre syndrome x
Cardiac disorder Cardiac disorder x x x x
Cardiomegaly Cardiomegaly x x x x x x x
Blood disorder Blood disorder x x x
Haemorrhage Haemorrhage x x x x x x x x
Haemoglobin Haemorrhage x x x x x x x x
Hyperbilirubinaemia Hyperbilirubinaemia x x x x x x x
Hypersensitivity Hypersensitivity x
Hypocalcaemia Hypocalcaemia x
Immunology test Immune status x x x x x x x
Immune system disorder Immune system disorder x
Inflammation Inflammation x x
Jaundice Jaundice x x x x x x x
Keratitis Keratitis x
Renal failure acute Renal failure acute x
Leukopenia Leukopenia x x x x x x x x
Liver abscess Liver abscess x x x x x x x x
Mediastinal disorder Mediastinal disorder x x x x
Meningitis Meningitis x
Infectious meningitis x x
Neuritis Neuritis x x x x x x x
Pancreatitis Pancreatitis x x x x x x x x
Paraplegia Paraplegia x x x
Monoplegia Paraplegia x x x
Diplegia Paraplegia x x x
Pericarditis Pericarditis x x x x x x x x
Peritonitis Peritonitis x x x x x x x x
Pneumatosis intestinalis Pneumatosis cystoides intestinalis x x x x x x x x
Polyp Polyp x x x
Psychotic disorder Psychotic disorder x
Pulmonary oedema Pulmonary oedema x x x x x x x x
Acute respiratory distress syndrome Acute respiratory distress syndrome x x
Rhabdomyolysis Rhabdomyolysis x
Skin ulcer Skin ulcer x x x x x x x x
Paraparesis Spastic paraparesis x
Thrombophlebitis Thrombophlebitis x x x x x x x x
Tumour lysis syndrome Tumour lysis syndrome x
Ulcer Ulcer x x x x x x x x
Ureteric obstruction Ureteric obstruction x
Urethral disorder Urinary tract disorder x x x x x
Urinary tract disorder Urinary tract disorder x x x x x
Urticaria Urticaria x x x x x x x
Angiopathy Angiopathy x x x x
Weight increased Weight increased x
Photophobia Photophobia x x
Hepatic function abnormal Hepatic function abnormal x x x x x x x x
Amylase increased Amylase increased x
Injection site reaction Injection site reaction x x
Hepatocellular injury Hepatocellular injury x x x x x x x
Liver injury Hepatocellular injury x x x x x x x
Liver injury x
Bone pain Bone pain x x x x x x x x
Eye pain Eye pain x x
Oesophageal ulcer Oesophageal ulcer x x x x x x x
Traumatic liver injury Liver injury x
Malnutrition Malnutrition x x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x x x
Interstitial lung disease Interstitial pneumonia x x x x x x x x
Malaise Malaise x x x x x x x x
Discomfort Malaise x x x x x x x x
Ill-defined disorder Malaise x x x x x x x x
Myalgia Myalgia x x x x x x x x
Tachypnoea Tachypnoea x
Neurological symptom Neurological symptom x
Skin exfoliation Skin exfoliation x x x x x x x x
Anal inflammation Anal inflammation x x x x x x x
Personality change Personality change x x x x x x x x
Oropharyngeal discomfort Throat sore x x x x x x x x
Oropharyngeal pain Throat sore x x x x x x x x
Disease progression Disease progression x x
Sepsis Sepsis x x x x x x x x
Hepatobiliary disease Hepatobiliary disease x
Leukoencephalopathy Leukoencephalopathy x x
Blood bilirubin increased Blood bilirubin increased x
Cognitive disorder Cognitive impairment x
Capillary leak syndrome Capillary leak syndrome x
Lacrimation increased Lacrimation x x
Sensation of foreign body Sensation of foreign body x x
Rash maculo-papular Rash maculo-papular x x x x x x x x
Transaminases increased Transaminases increased x
Respiratory distress Respiratory distress x x x x x x x
Visual impairment Visual disturbance x
Lipase increased Lipase increased x
Hypoxia Hypoxemia x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Febrile neutropenia Febrile neutropenia x
Amnesia Memory loss x
Allergic oedema Allergic oedema x x x x x x x
Infestation Infestation NOS x x x x x
Pancytopenia Myelosuppression x
Cardiotoxicity Cardiotoxicity x x x x x
Cardiomyopathy Cardiomyopathy x x x x x x x x
Pulmonary toxicity Pulmonary toxicity x x x x x x x
Venoocclusive disease Venoocclusive disease x
Necrotising colitis Necrotising colitis x x x x x x x x
Ileus Ileus x
Ocular toxicity Ocular toxicity x
Urine output Urine output x
Vasculitis necrotising Vasculitis necrotising x
Cytarabine syndrome Cytarabine syndrome x x x x x x x x
Gastrointestinal necrosis Intestinal necrosis x x x x x x x x
Non-cardiogenic pulmonary oedema Non-cardiogenic pulmonary oedema x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

CYTARABINE / DEPOCYT

Side effects:22
Source:FDA

CYTARABINE / DEPOCYT

Side effects:25
Source:Health Canada

cytarabine / cytarabine

Side effects:45
Source:EMA

CYTARABINE

Side effects:82
Source:FDA Structured Product Label

cytarabine liposome injection / DepoCyt

Side effects:83
Source:FDA

CYTARABINE / DEPOCYT

Side effects:83
Source:FDA

CYTARABINE

Side effects:65
Source:FDA Structured Product Label

CYTARABINE

Side effects:65
Source:FDA Structured Product Label

CYTARABINE

Side effects:66
Source:FDA Structured Product Label

CYTARABINE

Side effects:66
Source:FDA Structured Product Label

CYTARABINE

Side effects:66
Source:FDA Structured Product Label

CYTARABINE / CYTOSAR 100 MG

Side effects:77
Source:Health Canada

Cytarabine

Side effects:117
Source:BC Cancer

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label