Cytarabine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Headache def 32% - 56.4% x x x x x
Nausea def 30.8% - 54% x x x x x
Weakness def 7% - 54% x x
Fatigue def 25% - 46% x
Body temperature increased def 19.2% - 45% x x x x x
Vomiting def 28.2% - 44% x x x x x
Arachnoiditis def 19.2% - 42% x x x
Confusional state def 11% - 36% x x x
Neutropenia def 10% - 36% x x x
Diarrhoea def 12% - 32% x x x x
Thrombocytopenia def 11% - 32% x x x x x x
Pain def 7.69% - 29% x x x x x
Pain in extremity def 12% - 29% x
Gait disturbance def 21% - 29% x x x
Death 14% - 27% x x x
Constipation def 24% - 25% x x
Oedema def 2% - 25% x x x x x
Oedema peripheral def 11% - 25% x x
Insomnia def 14% - 25% x
Back pain def 17.9% - 24% x x x
Convulsion def 3.57% - 21.8% x
Cough def 7% - 21% x x
Dizziness def 18% - 21% x x x x
Dyspnoea def 10% - 21% x x x x
Anaemia def 12% - 18% x x x x x x
Anorexia def 3% - 18% x x x x
Dehydration def 11% - 18% x
Hypotension def 7% - 18% x
Incontinence def 7% - 18% x x
Infection def 14% - 18% x x x x x
Tachycardia def 0% - 18% x
Tremor def 9% - 18% x x
Urinary tract infection def 14% - 18% x
Hearing impaired def 6% - 18% x
Lethargy def 12% - 16% x
Abdominal pain def 9% - 15% x x x x
Neck pain def 7.69% - 15% x x
Hypertension def 4% - 15% x
Hypokalaemia def 7% - 15% x x
Agitation def 7% - 15% x
Muscular weakness def 7% - 15% x x
Neck stiffness 1.28% - 14.3% x x x
Stiffness 1.28% - 14.3% x x
Arthralgia def 9% - 14% x
Pruritus def 0% - 14% x x x x
Memory impairment def 4% - 14% x
Vision blurred def 11% - 14% x x
Hyperglycaemia def 6% - 12% x
Hypoaesthesia def 10% - 12% x x
Hyponatraemia def 4% - 12% x
Inflammation def 3% - 12% x x x x
Neuropathy peripheral def 4% - 12% x
Decreased appetite 11% - 12% x
Mucosal inflammation def 3% - 12% x x
Neuropathy def 3% - 12% x x x x
Anxiety def 3% - 11% x
Dysphagia def 8% - 11% x
Haemorrhoids def 0% - 11% x
Pneumonia def 6% - 11% x x x x
Reflexes abnormal def 0% - 11% x
Sweating def 2% - 11% x
Syncope def 0% - 11% x
Urinary retention def 0% - 11% x x x x
Peripheral sensory neuropathy def 3% - 11% x
Platelet count decreased 0% - 11% x
Sweating increased 2% - 11% x
Abscess def x x x
Aggression def x
Alopecia def x x x
Anaphylactic shock def x x x
Anaemia megaloblastic def x
Asthenia def x
Mental disorder def x
Cellulitis def x x x
Central nervous system disorder def x
Cerebellar syndrome def x x x
Chest pain def x x x
Colitis def x x x
Coma def x x
Conjunctivitis def x x x
Connective tissue disorder def x
Cyst def x
Toxic epidermal necrolysis def x x
Oesophageal disorder def x x
Oesophagitis def x x x
Rash def x x x
Extravasation def x
Eye disorder def x
Ephelides x x x
Gastrointestinal disorder def x
Gastrointestinal haemorrhage def x
Cardiac arrest def x
Cardiac disorder def x
Cardiomegaly def x x x
Haemorrhage def x x x
Hydrocephalus def x
Hyperbilirubinaemia def x x x
Hypersensitivity def x
Hypocalcaemia def x
Immune status def x x x
Influenza def x
Unspecified disorder of intestine def x
Jaundice def x x
Keratitis def x
Renal failure acute def x
Leukopenia def x x x x
Liver abscess def x x x
Mediastinal disorder def x
Meningism def x x x
Meningitis def x x
Muscle rigidity def x
Necrosis def x x x
Nervous system disorder def x x x
Neuritis def x x
Obstruction def x
Pancreatic disorder def x
Pancreatitis def x x x
Paraplegia def x
Paraesthesia def x
Pericarditis def x x x
Peritonitis def x x x
Pneumatosis cystoides intestinalis def x x x
Polyp def x
Psychotic disorder def x
Pulmonary oedema def x x x
Renal failure def x
Acute respiratory distress syndrome def x
Rhabdomyolysis def x
Seizures def x
Skin ulcer def x x x
Spastic paraparesis def x
Thrombophlebitis def x x x
Tumour lysis syndrome def x
Ulcer def x x x
Ureteric obstruction def x
Uric acid level increased x
Urinary incontinence def x
Urinary tract disorder def x
Urticaria def x x
Angiopathy def x
Vasculitis def x
Weight increased def x
Hypoalgesia x
Photophobia def x
Hepatic function abnormal x x x
Amylase increased x
Injection site reaction def x
Hepatocellular injury x x
Bone pain def x x x x
Eye pain def x
Oesophageal ulcer def x x
Interstitial pneumonia x x x
Paraparesis def x
Malaise def x x x x
Myalgia def x x x x
Tachypnoea def x
Tenderness def x x x
Skin exfoliation x x x
Anal inflammation x x
Personality change def x x x
Throat sore def x x x
Disease progression def x
Sepsis def x x x
Leukoencephalopathy def x
Hydrocephalus acquired x
Solid tumour def x
Pneumatosis x x x
Cognitive impairment def x
Renal impairment def x
Capillary leak syndrome def x
Lacrimation def x
Sensation of foreign body def x
Rash maculo-papular def x x x x
Transaminases increased x
Blindness def x
Respiratory distress def x x x
Lymphadenopathy def x
Lipase increased def x
Cardio-respiratory arrest def x
Hypoxemia def x
Dissecting aortic aneurysm, thoracic x
Infectious meningitis def x
Hyperuricaemia def x
Febrile neutropenia def x
Memory loss x
Allergic oedema x x
Infestation NOS x x
Cardiomyopathy def x x x
Pulmonary toxicity x x x
Necrotising colitis x x x
Ileus def x
Urine output x
Vasculitis necrotising def x
Cytolysis def x
Leptomeningeal metastases def x x
Intestinal necrosis x x x
Somnolence def x x x x
Indication Labels
Acute leukaemia def x
Acute lymphocytic leukaemia def x x x
Acute myeloid leukaemia def x
Blast cell crisis def x x x
Cancer in remission x x x
Chronic lymphocytic leukaemia def x
Chronic myeloid leukaemia def x x x
Erythroleukaemia def x
Leukaemia def x x x x
Lichen sclerosus def x
Lymphocytic leukaemia def x x x
Lymphoma def x x
Meningeal leukemia def x x x
Meningeal neoplasm def x
Myelodysplastic syndrome def x
Myeloid leukaemia def x x x
Neoplasm def x
Neoplasm malignant def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: L01BC01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. CYTARABINE / CYTOSAR 100 MG : 10 side effects (Health Canada)
  2. CYTARABINE / DEPOCYT : 28 side effects (Drugs@FDA)
  3. CYTARABINE / DEPOCYT : 85 side effects (Drugs@FDA)
  4. CYTARABINE : 75 side effects (FDA XML label)
  5. CYTARABINE : 75 side effects (FDA XML label)
  6. Cytarabine : 130 side effects (BC Cancer)