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Side effects

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MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3
Body temperature increased Body temperature increased 60% - 69% x x x
Asthenia Asthenia 9% - 65% x x x
Fatigue 10% - 38% x x x
Infection Infection 33% - 44% x x x
Cough Cough 10% - 44% x x x
Fatigue Fatigue 10% - 38% x x x
Decreased appetite Anorexia 7% - 34% x x x
Nausea Nausea 31% - 36% x x x
Vomiting Vomiting 31% - 36% x x x
Dyspnoea Dyspnoea 9% - 22% x x x
Pain Pain 20% - 22% x x
Pneumonia Pneumonia 16% - 22% x x x
Chills Chills 11% - 19% x x x
Upper respiratory tract infection Upper respiratory tract infection 2% - 16% x x
Visual impairment Visual disturbance 3% - 15% x x x
Diarrhoea Diarrhoea 13% - 15% x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage 3% - 13% x x x
Hyperhidrosis Sweating increased 1% - 13% x x
Paraesthesia Paraesthesia 4% - 12% x x
Pharyngitis Pharyngitis 0% - 9% x x
Alveolitis allergic Alveolitis allergic 0% - 6% x x
Haemoptysis Haemoptysis 1% - 6% x x
Hyperglycaemia Hyperglycaemia 1% - 6% x x
Malaise Malaise 6% - 8% x x x
Discomfort Malaise 6% - 8% x x x
Feeling abnormal Malaise 6% - 8% x x x
Confusional state x x x
Ill-defined disorder Malaise 6% - 8% x x x
Deafness Hearing impaired 2% - 6% x x
Hearing impaired Hearing impaired 2% - 6% x x
Alopecia Alopecia 0% - 3% x x
Sleep disorder Sleep disorder 1% - 3% x x
Anaphylactic shock Anaphylactic shock 0% - 1% x x
Anaemia Anaemia x x x
Autoimmune haemolytic anaemia Autoimmune haemolytic anaemia x x x
Aneurysm Aneurysm x x
Angina pectoris Angina pectoris x x
Arrhythmia Arrhythmia x x x
Arthralgia Arthralgia x x
Musculoskeletal discomfort Arthralgia x x
Myalgia x x
Bronchitis Bronchitis 0% - 1% x x
Cerebellar syndrome Cerebellar syndrome 0% - 1% x x
Nervous system disorder Cerebellar syndrome 0% - 1% x x
Transient ischaemic attack Transient ischaemic attack x x
Cholelithiasis Cholelithiasis x x
Coma Coma x x x
Confusional state Confusional state x x x
Constipation Constipation x x
Pancytopenia Cytopenia x x
Pancytopenia x x
Bone marrow depression x x
Myelosuppression x x x
Dysphagia Dysphagia x x
Dehydration Dehydration 0% - 1% x x
Dysuria Dysuria x x
Oedema Oedema x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis x
Epistaxis Epistaxis 0% - 1% x x
Oesophagitis Oesophagitis 0% x x
Dermatitis Rash x x x
Rash Rash x x x
Fibrosis Fibrosis x x x
Flank pain Flank pain x x x
Headache Headache 0% - 3% x x
Cardiac failure Cardiac failure x
Cardiac failure congestive Cardiac failure congestive x x
Haematuria Haematuria x x x
Haemorrhage Haemorrhage 0% - 1% x x
Haemoglobin Haemorrhage 0% - 1% x x
Herpes zoster Herpes zoster x
Hyperkalaemia Hyperkalaemia x x x
Hypersensitivity Hypersensitivity x x x
Hypocalcaemia Hypocalcaemia x x x
Progressive multifocal leukoencephalopathy Progressive multifocal leukoencephalopathy x
Leukopenia Leukopenia x
Lymphoproliferative disorder Lymphoproliferative disorder x
X-linked lymphoproliferative syndrome Lymphoproliferative disorder x
Myelodysplastic syndrome Myelodysplastic syndrome x
Myocardial infarction Myocardial infarction x x
Acute coronary syndrome Myocardial infarction x x
Neutropenia Neutropenia x x x
Hypoaesthesia Numbness x
Sensory loss Numbness x
Opportunistic infection Opportunistic infection x x x
Optic nerve disorder Optic nerve disorder x
Optic neuritis Optic neuritis x
Osteoporosis Osteoporosis x x
Pericardial effusion Pericardial effusion x x x
Neuropathy peripheral Neuropathy peripheral x x x
Phlebitis Phlebitis x x
Proteinuria Proteinuria x x
Protein urine present Proteinuria x x
Pruritus Pruritus x x
Pulmonary fibrosis Pulmonary fibrosis x x
Renal failure Renal failure x x x
Seborrhoeic dermatitis Seborrhoeic dermatitis x x
Convulsion Convulsion x
Sinusitis Sinusitis 0% - 5% x x
Erythema multiforme Stevens-Johnson syndrome x
Stevens-Johnson syndrome Stevens-Johnson syndrome x
Stomatitis Stomatitis 0% - 9% x x x
Cerebrovascular accident Cerebrovascular accident x x
Supraventricular tachycardia Supraventricular tachycardia x x
Thrombocytopenia Thrombocytopenia x x x
Tumour lysis syndrome Tumour lysis syndrome x x x
Urinary tract infection Urinary tract infection x x
Immunodeficiency Immunocompromised x
Hepatic failure Hepatic failure x x
Agitation Agitation x x x
Hyperphosphataemia Hyperphosphataemia x x x
Cystitis haemorrhagic Cystitis haemorrhagic x x x
Epstein-Barr virus infection Epstein-Barr virus infection x
Deep vein thrombosis Deep vein thrombosis x x
Crystalluria Urate crystalluria x x x
Pulmonary haemorrhage Pulmonary haemorrhage x x
Liver function test abnormal Liver function test abnormal x x
Urinary hesitation Urinary hesitation x x
Haemoglobin decreased Haemoglobin decreased x x
Malnutrition Malnutrition x
Metabolic acidosis Metabolic acidosis x x x
Myalgia Myalgia x x
Radial nerve palsy Wrist drop x x x
Dyspepsia Digestion impaired x x x
Gastrointestinal disorder Digestion impaired x x x
Neurotoxicity Neurotoxicity x
Lung infiltration Lung infiltration x x x
Renal function test abnormal Renal function test abnormal x x
Hypoxia Hypoxia 0% - 1% x x
Aplasia Aplasia x x
Mucosal inflammation Mucosal inflammation 0% x x x
Blindness Blindness x
Respiratory distress Respiratory distress x x
Blood uric acid increased Hyperuricaemia x x x
Hyperuricaemia Hyperuricaemia x x x
Pulmonary toxicity Pulmonary toxicity x x
Respiratory failure Respiratory failure x x
Skin toxicity Skin toxicity x x
Neutrophil count decreased Absolute neutrophil count decreased x x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:104


Side effects:104

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label