Posaconazole

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Abdominal distension def Abdominal distension def x
Distention def x
Abdominal pain def Abdominal pain def x x
Gastrointestinal pain def Abdominal pain def x x
Acidosis def Acidosis def x
Renal tubular acidosis def Renal tubular acidosis def x
Road traffic accident Renal tubular acidosis def x
Adrenal insufficiency def Adrenal insufficiency def x x
Agranulocytosis def Agranulocytosis def x
Albuminuria def Albuminuria def x
Alopecia def Alopecia def x
Amnesia def Amnesia def x
Anaemia def Anaemia def x x
Anaemia NOS aggravated x
Aplastic anaemia def Aplastic anaemia def x
Decreased appetite Anorexia def x x
Anxiety def Anxiety def x x
Arrhythmia def Arrhythmia def x x
Arthralgia def Arthralgia def x x
Musculoskeletal discomfort Arthralgia def x x
Myalgia def x
Ascites def Ascites def x
Asthenia def Asthenia def x x
Fatigue def x x
Weakness def x x
Ataxia def Ataxia def x
Atelectasis def Atelectasis def x
Arteriosclerosis def Atherosclerosis def x
Atrial fibrillation def Atrial fibrillation def x
Atrial flutter def Atrial flutter def x
Atrioventricular block def Atrioventricular block def x
Back pain def Back pain def x x
Bacteraemia def Bacteraemia def x
Balanoposthitis Balanoposthitis x
Mental disorder def Mental disorder def x
Mental state abnormal x
Coagulopathy def Coagulopathy def x x
Bundle branch block def Bundle branch block def x
Candidiasis def Oral candidiasis def x
Oral candidiasis def Oral candidiasis def x
Cardiovascular disorder def Cardiovascular disorder def x
Cellulitis def Cellulitis def x
Cheilitis def Cheilitis def x
Chest pain def Chest pain def x
Musculoskeletal chest pain Chest wall pain def x
Cholestasis def Cholestasis def x
Confusional state def Confusional state def x
Feeling abnormal Confusional state def x
Malaise def x
Conjunctivitis def Conjunctivitis def x
Constipation def Constipation def x x
Convulsion def Convulsion def x
Cough def Cough def x x
Dry cough x
Cytomegalovirus infection def Cytomegalovirus infection def x
Sudden death def Sudden death def x
Libido decreased def Libido decreased def x
Disturbance in sexual arousal Libido decreased def x
Dysphagia def Dysphagia def x
Dehydration def Dehydration def x x
Delirium def Delirium def x
Dermatitis def Dermatitis def x
Rash def x x
Diarrhoea def Diarrhoea def x x
Diplopia def Diplopia def x
Diverticulitis def Diverticulitis def x
Dizziness def Dizziness def x x
Syncope def x
Dysgeusia def Dysgeusia def x
Dyspepsia def Dyspepsia def x x
Dyspnoea def Dyspnoea def x x
Dysuria def Dysuria def x
Ear pain def Ear pain def x
Ecchymosis def Ecchymosis def x
Oedema def Oedema def x x
Embolism def Embolism def x x
Endocrine disorder def Endocrine disorder def x
Hormone level abnormal Endocrine disorder def x
Eosinophilia def Eosinophilia def x
Epistaxis def Epistaxis def x x
Eructation def Eructation def x
Oesophageal disorder def Oesophageal disorder def x
Oesophagitis def Oesophagitis def x
Rash def Rash def x x
Fasciitis def Fasciitis def x
Fatigue def Fatigue def x x
Body temperature increased def Body temperature increased def x x
Fistula def Fistula def x
Flank pain def Flank pain def x
Flatulence def Flatulence def x
Flushing def Flushing def x
Cardiac flutter Cardiac flutter x
Furuncle def Furunculosis def x
Gastritis def Gastritis def x
Gastroenteritis def Gastroenteritis def x
Gastrooesophageal reflux disease def Gastrooesophageal reflux disease def x
Gingivitis def Gingivitis def x
Glossitis def Glossitis def x
Transplant rejection def Transplant rejection def x
Headache def Headache def x x
Cardiac arrest def Cardiac arrest def x
Cardiac disorder def Cardiac disorder def x
Cardiomegaly def Cardiomegaly def x
Cardiac failure def Cardiac failure def x
Haematoma def Haematoma def x
Haematuria def Haematuria def x
Hemiparesis Hemiparesis x
Haemolytic uraemic syndrome def Haemolytic uraemic syndrome def x x
Haemorrhage def Haemorrhage def x x
Haemoglobin def Haemorrhage def x x
Hepatitis def Hepatitis def x x
Hepatomegaly def Hepatomegaly def x x
Hepatosplenomegaly Hepatosplenomegaly x
Herpes virus infection def Herpes NOS def x
Oral herpes Herpes labialis def x
Herpes simplex def Herpes simplex def x
Hiccups def Hiccups def x
HIV infection def HIV infection def x x
Hyperbilirubinaemia def Hyperbilirubinaemia def x x
Hyperbilirubinemia aggravated x
Hypercalcaemia def Hypercalcaemia def x
Hypercholesterolaemia def Hypercholesterolaemia def x
Hyperglycaemia def Hyperglycaemia def x x
Hyperkalaemia def Hyperkalaemia def x
Hyperlipidaemia def Hyperlipidaemia def x
Hypernatraemia def Hypernatraemia def x
Hypersensitivity def Hypersensitivity def x x
Hypertension def Hypertension def x x
Pulmonary hypertension def Pulmonary hypertension def x
Hypertriglyceridaemia def Hypertriglyceridaemia def x
Blood triglycerides increased Hypertriglyceridaemia def x
Hypertrophy def Hypertrophy def x
Hypoaesthesia def Hypoaesthesia def x
Hypocalcaemia def Hypocalcaemia def x x
Hypokalaemia def Hypokalaemia def x x
Potassium deficiency def x
Hyponatraemia def Hyponatraemia def x
Hypotension def Hypotension def x x
Orthostatic hypotension def Orthostatic hypotension def x
Immune system disorder def Immune system disorder def x
Infarction def Infarction def x
Inflammation def Inflammation def x
Influenza def Influenza def x
Ischaemia def Ischaemia def x
Jaundice def Jaundice def x x
Nephrolithiasis def Calculus of kidney def x
Renal failure acute def Renal failure acute def x x
Leukaemia def Leukaemia def x
Acute myeloid leukaemia def Acute myeloid leukaemia def x
Acute leukaemia def Acute myeloid leukaemia def x
Myeloid leukaemia def x
Myeloid leukaemia def Myeloid leukaemia def x
Leukopenia def Leukopenia def x
Lipoma def Lipoma def x
Breast pain def Breast pain def x
Melaena def Melaena def x
Meningism def Meningism def x
Meningitis def Meningitis def x
Menstrual disorder def Menstrual disorder def x
Metabolic disorder def Metabolic disorder def x
Mitral valve disease def Mitral valve disease def x
Muscle spasms def Cramp muscle def x
Hypotonia def Hypotonia def x
Muscle relaxant therapy Hypotonia def x
Musculoskeletal disorder def Musculoskeletal disorder def x
Musculoskeletal pain def Musculoskeletal pain def x x
Myelodysplastic syndrome def Myelodysplastic syndrome def x
Myocardial infarction def Myocardial infarction def x
Acute coronary syndrome def Myocardial infarction def x
Nasal congestion def Nasal congestion def x
Nausea def Nausea def x x
Neoplasm def Neoplasm def x
Solid tumour def x
Nephritis def Nephritis def x
Tubulointerstitial nephritis Nephritis interstitial def x
Nervous system disorder def Nervous system disorder def x
Neuritis def Neuritis def x
Neuropathy peripheral def Neuritis def x
Neuropathy peripheral def x
Neuropathy def x
Night sweats def Night sweats def x
Nightmare def Nightmare def x
Blood urea increased NPN increased x
Blood urea increased x
Nodule def Nodule def x
Nocturia def Nocturia def x
Obstruction def Obstruction def x
Pain def Pain def x x
Pain worsened x
Pallor def Pallor def x
Palpitations def Palpitations def x
Pancreatitis def Pancreatitis def x
Pancytopenia def Pancytopenia def x
Paraplegia def Paraplegia def x
Monoplegia Paraplegia def x
Diplegia Paraplegia def x
Paraesthesia def Paraesthesia def x x
Petechiae def Petechiae def x
Pharyngitis def Pharyngitis def x x
Pneumonia def Pneumonia def x x
Upper-airway cough syndrome Postnasal drip def x
Blood potassium decreased Potassium deficiency def x
Supraventricular extrasystoles def Supraventricular extrasystoles def x
Prurigo def Prurigo def x
Pruritus def Pruritus def x x
Psychotic disorder def Psychotic disorder def x
Pulmonary embolism def Pulmonary embolism def x x
Purpura def Purpura def x x
Vascular purpura Purpura def x x
Thrombotic thrombocytopenic purpura def Thrombotic thrombocytopenic purpura def x x
Rales Rales x
Proctalgia def Proctalgia def x
Rectal tenesmus def x
Renal failure def Renal failure def x x
Renal insufficiency aggravated x
Insufficiency renal def x
Respiratory disorder def Respiratory disorder def x x
Respiratory failure def Respiratory insufficiency def x
Respiratory tract infection def Respiratory tract infection def x x
Restless legs syndrome def Restless legs syndrome def x
Rhinitis def Rhinitis def x
Sarcoidosis def Sarcoidosis def x
Sciatica def Sciatica def x
Scotoma def Scotoma def x
Seborrhoeic dermatitis def Seborrhoeic dermatitis def x
Sinusitis def Sinusitis def x
Skin disorder def Skin disorder def x
Skin mass Skin nodule def x
Speech disorder def Speech disorder def x
Splenomegaly def Splenomegaly def x
Erythema multiforme def Stevens-Johnson syndrome def x
Stevens-Johnson syndrome def Stevens-Johnson syndrome def x
Gastric disorder def Gastric disorder def x
Stomatitis def Stomatitis def x
Mouth ulceration def x
Cerebrovascular accident def Cerebrovascular accident def x
Hyperhidrosis def Sweating def x x
Sweating increased x x
Shock def Syncope def x
Syncope def Syncope def x
Loss of consciousness def Syncope def x
Tachycardia def Tachycardia def x x
Sinus tachycardia def Sinus tachycardia def x
Supraventricular tachycardia def Supraventricular tachycardia def x
Thirst def Thirst def x
Thrombocytopenia def Thrombocytopenia def x x
Thrombosis def Thrombosis def x
Tinnitus def Tinnitus def x
Tongue disorder Tongue disorder x
Tooth discolouration def Tooth discolouration def x
Torsade de pointes def Torsade de pointes def x x
Tremor def Tremor def x
Ulcer def Ulcer def x
Erythema def Erythema def x
Upper respiratory tract infection def Upper respiratory tract infection def x x
Pollakiuria def Pollakiuria def x
Urinary tract infection def Urinary tract infection def x
Micturition disorder def Micturition disorder def x
Urethral disorder def Urinary tract disorder def x
Urinary tract disorder def Urinary tract disorder def x
Urticaria def Urticaria def x
Angiopathy def Angiopathy def x x
Vasculitis def Vasculitis def x
Venous thrombosis def Venous thrombosis def x
Ventricular tachycardia def Ventricular tachycardia def x
Vertigo def Vertigo def x
Vestibular disorder def Vestibular disorder def x
Vitamin K deficiency def Vitamin K deficiency def x
Vomiting def Vomiting def x x
Weight increased def Weight increased def x
Weight decreased def Weight decreased def x x
Dry mouth def Dry mouth def x
Encephalopathy def Encephalopathy def x
Hepatic failure def Hepatic failure def x
Stupor def Stupor def x
Depressed level of consciousness def Stupor def x
Agitation def Agitation def x
Hyperkinesia def x
Mood swings Mood swings x
Affect lability Mood swings x
Photophobia def Photophobia def x
Oedema peripheral def Oedema peripheral def x
Leg edema x x
Hyperphosphataemia def Hyperphosphataemia def x
Hypophosphataemia def Hypophosphataemia def x
Hepatic function abnormal Hepatic function abnormal x x
Mouth ulceration def Mouth ulceration def x
Deep vein thrombosis def Deep vein thrombosis def x
Hepatitis cholestatic Hepatitis cholestatic x
Migraine def Migraine def x
Periorbital oedema def Periorbital oedema def x
Musculoskeletal stiffness Neck stiffness x
Stiffness x
Nuchal rigidity Neck stiffness x
Blood amylase increased Amylase increased x
Coagulation time prolonged Coagulation time prolonged x
Creatinine renal clearance decreased Creatinine renal clearance decreased x
Blood creatinine increased Creatinine increased def x
Diarrhoea haemorrhagic Diarrhoea haemorrhagic x
Tongue discolouration Tongue discolouration x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Electroencephalogram abnormal Electroencephalogram abnormal x
Electrolyte imbalance def Electrolyte abnormality x
Blood electrolytes abnormal Electrolyte abnormality x
Ventricular extrasystoles def Ventricular extrasystoles def x
Blood gonadotrophin decreased Gonadotropins NOS low x
Neutrophilia Neutrophilia x
Hypomagnesaemia def Hypomagnesaemia def x x
Renal impairment def Kidney function abnormal x
Renal tubular disorder def Renal tubular disorder def x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased x
Hepatocellular injury Hepatocellular injury x
Liver injury Hepatocellular injury x
Cytolytic hepatitis Hepatocellular injury x
Liver function test abnormal Liver function test abnormal x
Liver tenderness Liver tenderness x
Muscular weakness def Muscular weakness def x
Bone pain def Bone pain def x
Eye pain def Eye pain def x
Blood alkaline phosphatase increased def Phosphatase alkaline increased x
Platelet disorder def Abnormal platelets x
Prothrombin level increased Prothrombin level increased x
Hyporeflexia Hyporeflexia x
Hyperreflexia Hyperreflexia x
Aspartate aminotransferase increased def Aspartate aminotransferase increased def x
Alanine aminotransferase increased def Alanine aminotransferase increased def x
Dry skin def Dry skin def x
Oesophageal ulcer def Oesophageal ulcer def x
Haemoglobin decreased def Haemoglobin decreased def x
Respiratory arrest Respiratory arrest x
Malnutrition def Malnutrition def x
Urinary tract obstruction def Urinary tract obstruction def x
Interstitial lung disease def Interstitial pneumonia x
Metabolic acidosis def Metabolic acidosis def x
Odynophagia Odynophagia x
Rash macular Rash macular x
Rash vesicular Rash vesicular x
Malaise def Malaise def x
Discomfort def Malaise def x
Ill-defined disorder Malaise def x
Myalgia def Myalgia def x
Muscle twitching def Muscle twitching def x
Cardiac fibrillation Cardiac fibrillation x
Increased appetite Increased appetite x
Abdominal tenderness Abdominal tenderness x
Retching def Retching def x
Rectal tenesmus def Rectal tenesmus def x
Anorectal discomfort Rectal tenesmus def x
Asterixis def Asterixis def x
Memory impairment def Memory impairment def x
Areflexia Areflexia x
Tenderness def Tenderness def x
Rash erythematous Rash erythematous x
Rash follicular Rash follicular x
Disturbance in attention Cerebration impaired def x
Mental disability Cerebration impaired def x
Dry throat Dry throat x
Eye irritation Eye irritation x
Gravitational oedema Gravitational oedema x
Urine abnormality Urine abnormality x
Urine analysis abnormal Urine abnormality x
Saliva altered Saliva altered x
Mononeuritis Mononeuritis x
Lung infiltration Lung infiltration x
Hepatic enzyme increased Hepatic enzyme increased x x
Oesophageal candidiasis Oesophageal candidiasis x
Hypoalbuminaemia def Hypoalbuminaemia def x
Nasal discomfort Nasal irritation x
Sepsis def Sepsis def x
Aplasia Aplasia x
Hyperproteinaemia def Hyperproteinaemia def x
Major depression def Depressive type psychosis x
Cholelithiasis def Biliary sludge x
Azotaemia def Uraemic syndrome x x
Dry eye Dry eye x
Mucosal inflammation def Mucosal inflammation def x x
Ventricular hypertrophy def Ventricular hypertrophy def x
Extrasystoles def Extrasystoles def x
Vision blurred def Vision blurred def x
Platelet count decreased Platelet count decreased x
Dystonia def Dystonia def x
Rash maculo-papular def Rash maculo-papular def x
Hyperkinesia def Hyperkinesia def x
Chills def Rigors x x
Bradycardia def Bradycardia def x
Laboratory test abnormal Laboratory test abnormal x
Blood gases abnormal Blood gases abnormal x
Lymphadenopathy def Lymphadenopathy def x
Electrocardiogram abnormal Electrocardiogram abnormal x
Face oedema def Face oedema def x
Lipase increased def Lipase increased def x
Prothrombin level decreased Prothrombin level decreased x
Gait disturbance def Gait disturbance def x
Menopausal symptoms def Hot flush def x
Hot flush def Hot flush def x
Drug interaction def Drug interaction def x
Acne def Acne def x
Aortic dissection def Dissecting aortic aneurysm, thoracic x
Blood uric acid increased Hyperuricaemia def x
Hyperuricaemia def Hyperuricaemia def x
Ejection fraction decreased def Ejection fraction decreased def x
Febrile neutropenia def Febrile neutropenia def x
White blood cell count decreased White blood cell count decreased x
Thrombocytosis def Thrombocytosis def x
Infestation Infestation NOS x x
Sleep disorder def Sleep disorder def x
Neutrophil count decreased def Neutrophil count decreased def x
Pseudomonas infection def Infection pseudomonas aeruginosa x
Thrombocytopenic purpura def Thrombocytopenic purpura def x x
Device related infection def Catheter related infection def x
Insomnia def Insomnia def x x
Severe acute respiratory syndrome def Severe acute respiratory syndrome def x
Ileus def Ileus def x
Nasopharyngitis def Rhinorrhoea def x
Rhinorrhoea def Rhinorrhoea def x
Sarcoma def Sarcoma def x
Death Death x
Deafness def Hearing impaired def x
Hearing impaired def Hearing impaired def x
Aortic valve sclerosis Aortic valve sclerosis x
Dysphonia def Dysphonia def x
Floppy iris syndrome Intraoperative floppy iris syndrome x
Gastritis haemorrhagic Gastritis haemorrhagic x
Somnolence def Somnolence def x
Vaginal haemorrhage def Vaginal haemorrhage def x
Indication Labels
Antifungal treatment x
Aspergillosis def x
Candidiasis def x x
Disease progression def x
Elderly def x
Fungal infection def x x
Graft versus host disease def x
Haematological malignancy def x
Infection def x x
Neoplasm malignant def x
Neutropenia def x x
Oropharyngeal candidiasis def x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: J02AC04

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. posaconazole : 91 side effects (FDA XML label)
  2. POSACONAZOLE / POSANOL : 360 side effects (Health Canada)