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Thrombotic thrombocytopenic purpura

Definition: An acute or subacute syndrome characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurologic abnormalities such as seizures, hemiplegia, and visual disturbances. Drugs and bacteria have been implicated as etiologic factors. The introduction of plasma exchange has significantly lowered the mortality rate. If untreated, the mortality rate is high.

Synonyms (terms occurring on more labels are shown first): thrombotic thrombocytopenic purpura

More information: PubMed search and possibly Wikipedia

Show drugs for which this side effect directly occurs

Drugs with this side effect as MedDRA Preferred Term

  • D-penicillamine
    • Thrombotic thrombocytopenic purpura
  • FK463
    • Thrombotic thrombocytopenic purpura
  • K779
    • Thrombotic thrombocytopenic purpura: postmarketing
  • VACV
    • Thrombotic thrombocytopenic purpura: postmarketing
  • acyclovir
    • Thrombotic thrombocytopenic purpura
  • clopidogrel
    • Thrombotic thrombocytopenic purpura: very rare, postmarketing
  • everolimus
    • Thrombotic thrombocytopenic purpura: common, 0% - 1.46%
  • lansoprazole
    • Thrombotic thrombocytopenic purpura: postmarketing
  • medroxyprogesterone acetate
    • Thrombotic thrombocytopenic purpura
  • memantine
    • Thrombotic thrombocytopenic purpura: postmarketing
  • mycophenolate mofetil
    • Thrombotic thrombocytopenic purpura
  • ofloxacin
    • Thrombotic thrombocytopenic purpura: postmarketing
  • paclitaxel
    • Thrombotic thrombocytopenic purpura
  • paliperidone
    • Thrombotic thrombocytopenic purpura: postmarketing
  • pazopanib
    • Thrombotic thrombocytopenic purpura
  • posaconazole
    • Thrombotic thrombocytopenic purpura
  • prasugrel
    • Thrombotic thrombocytopenic purpura: very rare, postmarketing
  • quinidine
    • Thrombotic thrombocytopenic purpura
  • rapamycin
    • Thrombotic thrombocytopenic purpura: postmarketing
  • ribavirin
    • Thrombotic thrombocytopenic purpura
  • rifabutin
    • Thrombotic thrombocytopenic purpura
  • risperidone
    • Thrombotic thrombocytopenic purpura: postmarketing
  • tacrolimus
    • Thrombotic thrombocytopenic purpura: postmarketing, rare
  • terbinafine
    • Thrombotic thrombocytopenic purpura
  • v 1784
    • Thrombotic thrombocytopenic purpura: postmarketing
  • voriconazole
    • Thrombotic thrombocytopenic purpura

Drugs with this indication