Search results :

Paliperidone

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N05AX13

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10
Extrapyramidal disorder Extrapyramidal symptoms 4% - 23% 0% - 8% x x x x x x x x x x
Extrapyramidal disorder common, 2% - 7% 2% x x x x x x x x x
Headache Headache very common, 4% - 14% 4% - 12% x x x x x x x x x x
Somnolence Somnolence common, 6% - 26% 3% - 7% x x x x x x x x x x
Nausea Nausea 5% - 8% 5% - 6% x x x x x x x
Tachycardia Tachycardia common, 0% - 14% 0% - 7% x x x x x x x x x x
Dyspepsia Dyspepsia 5% - 6% 2% - 4% x x x x x x
Parkinsonism Parkinsonism common, 0% - 15% 0% - 9% x x x x x x x x x x
Akathisia Akathisia common, 3% - 17% 0% - 6% x x x x x x x x x x
Dizziness Dizziness common, 2% - 6% 0% - 4% x x x x x x x x x x
Syncope uncommon 1% x x x x x x x x x x
Sinus tachycardia Sinus tachycardia common, 4% - 9% 4% x x
Agitation Hyperkinesia 2% - 17% 0% - 5% x x x x x x x x x x
Agitation x x x x x x
Hyperkinesia Hyperkinesia 2% - 17% 0% - 5% x x x x x x x x x x
Bradycardia Bradycardia common 1% x x x x x x x x x x
Constipation Constipation 4% - 5% 2% x x x x x x
Dyskinesia Dyskinesia uncommon, 1% - 9% 0% - 3% x x x x x x x x x x
Movement disorder x
Abnormal involuntary movements x x
Hypertonia Hypertonia common, 1% - 4% 1% x x x x x x x x x x
Nervous system disorder Nervous system disorder postmarketing, 3% - 10% 4% x x x x x x x x x x
Vomiting Vomiting 0% - 11% 5% - 10% x x x x x x x x x
Weight increased Weight increased common, 1% - 7% 0% - 1% x x x x x x x x x x
Bundle branch block Bundle branch block common, 1% - 3% 2% x x x x x x x x x
Nasopharyngitis Nasopharyngitis 0% - 5% 1% - 3% x x x x x x
Tremor Tremor common, 2% - 12% 0% - 3% x x x x x x x x x x
Asthenia Asthenia common, 0% - 4% 0% - 1% x x x x x x x x x x
Fatigue common, 0% - 4% 0% - 1% x x x x x x x x x x
Dysarthria Dysarthria 1% - 4% 0% x x x x x x
Osteoarthritis Dysarthria 1% - 4% 0% x x x x x x
Fatigue Fatigue common, 0% - 4% 0% - 1% x x x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing, 1% - 3% 1% x x x x x x x x x x
Orthostatic hypotension Orthostatic hypotension common, 1% - 4% 1% x x x x x x x x x x
Upper respiratory tract infection Upper respiratory tract infection 2% 1% x x x x x x x
Angiopathy Angiopathy postmarketing, 1% - 4% 1% x x x x x x x x x x
Dry mouth Dry mouth 0% - 3% 1% - 2% x x x x x x x x x x
Atrioventricular block first degree Atrioventricular block first degree common, 0% - 2% 1% x x x x x x
Myalgia Myalgia 1% - 4% 1% x x x x x
Musculoskeletal discomfort Myalgia 1% - 4% 1% x x x x x
Arthralgia 1% x x x x x x x
Increased appetite Increased appetite uncommon, 2% - 3% 1% x x x x x x x
Abdominal pain upper Abdominal pain upper 0% - 3% 1% x x x x x x x x x
Sleep disorder Sleep disorder 0% - 3% 1% x x x x x x
Atrioventricular block Atrioventricular block 0% - 2% 1% x x x x
Anxiety Anxiety 0% - 9% 4% - 8% x x x x x
Sinus arrhythmia Sinus arrhythmia uncommon, 0% - 2% 0% x x x x x x x x x x
Back pain Back pain 1% - 3% 1% x x x x x x x
Cough Cough 1% - 3% 1% x x x x x x x
Cardiac disorder Cardiac disorder postmarketing, 0% - 2% 1% x x
Rhinitis Rhinitis 1% - 3% 0% - 1% x x x x x
Salivary hypersecretion Salivary hypersecretion 0% - 6% 0% - 1% x x x x x x x x x x
Decreased appetite Decreased appetite 0% - 2% 0% - 1% x x x x x x x
Anorexia x x
Abdominal discomfort Abdominal discomfort 0% - 3% 1% x x x x x x
Upset stomach 0% - 2% 1% x x x x
Laryngeal pain Pharyngolaryngeal pain 0% - 2% 1% x x x x x x
Connective tissue disorder Connective tissue disorder uncommon 1% x x x x x x x
Oedema Oedema uncommon x x x x x x x x x x
Pitting edema x x
Grand mal convulsion Grand mal convulsion uncommon x x x x x
Hypotension Hypotension uncommon 1% x x x x x
Ischaemia Ischaemia uncommon x x x x x x x x
Muscle rigidity Muscle rigidity uncommon 0% x x x x x x x
Palpitations Palpitations uncommon 0% x x x x x x x x x x
Shock Syncope uncommon 1% x x x x x x x x x x
Syncope Syncope uncommon 1% x x x x x x x x x x
Loss of consciousness Syncope uncommon 1% x x x x x x x x x x
Loss of consciousness x x
Malnutrition Malnutrition postmarketing, uncommon 0% x x x x x x x
Dizziness postural Dizziness postural uncommon x x x x x
Electrocardiogram abnormal Electrocardiogram abnormal uncommon 0% x x x x x
Alopecia Alopecia postmarketing x x
Anaphylactic shock Anaphylactic shock postmarketing x x x x x x x x x
Angioedema Angioedema postmarketing x x x x x
Mental disorder Mental disorder postmarketing 1% x x x x x x x
Breast disorder Breast disorder postmarketing x x x x x x x
Endocrine disorder Endocrine disorder postmarketing x x x
Eye disorder Eye disorder postmarketing x x x x x x x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion postmarketing x x
Jaundice Jaundice postmarketing x x
Mediastinal disorder Mediastinal disorder postmarketing x x x x x x x
Pancreatitis Pancreatitis postmarketing x x
Pregnancy Pregnancy postmarketing x x
Priapism Priapism very rare, postmarketing x x x x x x x x x
Thrombotic thrombocytopenic purpura Thrombotic thrombocytopenic purpura postmarketing x x x x x x x
Urinary incontinence Urinary incontinence postmarketing x x x x x x
Urethral disorder Urinary tract disorder postmarketing x x
Urinary tract disorder Urinary tract disorder postmarketing x x
Water intoxication Water intoxication postmarketing x x
Urinary retention Urinary retention very rare, postmarketing x x x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue postmarketing x x x x x x x
Swollen tongue Swollen tongue postmarketing, 0% - 3% 0% x x x x x x x x x
Hepatobiliary disease Hepatobiliary disease postmarketing x x
Tardive dyskinesia Tardive dyskinesia postmarketing x x x x x x x x x x
Ileus Ileus postmarketing x x x x
Floppy iris syndrome Floppy iris syndrome postmarketing x x
Agranulocytosis Agranulocytosis very rare, postmarketing x x x x x x
Atrial fibrillation Atrial fibrillation very rare, postmarketing x x
Diabetes mellitus Diabetes mellitus very rare, postmarketing x x x x x x
Diabetic ketoacidosis Diabetic ketoacidosis very rare, postmarketing x x
Dysgeusia Dysgeusia very rare, postmarketing x x
Hypoglycaemia Hypoglycaemia very rare, postmarketing x x
Body temperature decreased Body temperature decreased very rare, postmarketing x x
Hypothermia Body temperature decreased very rare, postmarketing x x
Drug withdrawal syndrome neonatal Drug withdrawal syndrome neonatal very rare, postmarketing x x
Pulmonary embolism Pulmonary embolism very rare, postmarketing x x
Sleep apnoea syndrome Sleep apnoea syndrome very rare, postmarketing x x
Thrombocytopenia Thrombocytopenia very rare, postmarketing x x
Deep vein thrombosis Deep vein thrombosis very rare, postmarketing x x
Mania Mania very rare, postmarketing x x
Abdominal pain Abdominal pain 1% x x x x x x x
Gastrointestinal pain Abdominal pain 1% x x x x x x x
Adenocarcinoma Adenocarcinoma x
Adenoma benign Adenoma benign x
Aggression Aggression 1% x
Albinism Albinism x
Amenorrhoea Amenorrhoea 0% - 6% 0% x x x x x x x
Anaemia Anaemia x x
Arthralgia Arthralgia 1% x x x x x x x
Athetosis Athetosis x x
Bipolar disorder Bipolar disorder x
Bipolar I disorder Bipolar disorder x
Blepharospasm Blepharospasm x x
Breast feeding Breast feeding x
Bronchitis Bronchitis 1% x x x
Cellulitis Cellulitis x x
Transient ischaemic attack Transient ischaemic attack x x
Cerebrovascular disorder Cerebrovascular disorder x x
Neck pain Neck pain 1% x x x
Cheilitis Cheilitis x x
Chest pain Chest pain x
Chest discomfort x x
Chorea Chorea x
Infection Infection x x x x x x x
Confusional state Confusional state x x
Feeling abnormal Confusional state x x
Malaise x x
Conjunctivitis Conjunctivitis x x
Muscle contracture Muscle contracture x
Cystitis Cystitis x x
Bladder pain Cystitis x x
Cystitis noninfective Cystitis x x
Libido decreased Libido decreased x x
Disturbance in sexual arousal Libido decreased x x
Dysphagia Dysphagia x x x x x x x x x
Depression Depression 1% x x
Drug eruption Drug eruption x x x
Diarrhoea Diarrhoea 2% x x x x
Drooling Drooling x x x x x x x
Dyspnoea Dyspnoea x x x x x x x x
Dysuria Dysuria x x
Ear pain Ear pain x x
Eczema Eczema x x
Epistaxis Epistaxis 0% - 2% 0% x x x
Dermatitis Rash x x x x x x
Rash Rash x x x x x x
Eye infection Eye infection x x
Faecal incontinence Faecal incontinence x x
Body temperature increased Body temperature increased 1% x x x
Flatulence Flatulence x x x x x x
Flushing Flushing x x
Gastroenteritis Gastroenteritis x x
Glaucoma Glaucoma x x
Glycosuria Glycosuria x x
Gynaecomastia Gynaecomastia 0% - 3% 0% x x x x x x x
Cardiac arrest Cardiac arrest x x
Hyperglycaemia Hyperglycaemia x x x x x x
Hyperinsulinism Hyperinsulinism x x x
Blood insulin increased Hyperinsulinism x x x
Blood insulin increased 1% x
Hyperprolactinaemia Hyperprolactinaemia x x x x x x x x x
Hypersensitivity Hypersensitivity x x x
Hypertension Hypertension x x x x x
Hypertriglyceridaemia Hypertriglyceridaemia x
Blood triglycerides increased Hypertriglyceridaemia x
Blood triglycerides increased 1% x x x
Hyperventilation Hyperventilation x x
Hypoaesthesia Hypoaesthesia x x
Immune system disorder Immune system disorder x x x x x x x x x x
Influenza Influenza x x
Intestinal obstruction Intestinal obstruction x x
Laryngospasm Laryngospasm x x
Bundle branch block left Bundle branch block left x x
Lethargy Lethargy 0% - 3% 0% x x x x
Leukopenia Leukopenia x x x x
Breast pain Breast pain x x x
Menorrhagia Menorrhagia x
Menstrual disorder Menstrual disorder x x x
Movement disorder Movement disorder x
Hypotonia Hypotonia x
Muscle relaxant therapy Hypotonia x
Musculoskeletal pain Musculoskeletal pain x x x x
Shoulder pain 0% x
Myoclonus Myoclonus x x
Myotonia Myotonia x x
Nasal congestion Nasal congestion 1% x x x x x x x
Nervousness Nervousness x
Tension Nervousness x
Neuroleptic malignant syndrome Neuroleptic malignant syndrome x x x x x x x x x
Neutropenia Neutropenia x x x x x x
Nightmare Nightmare 0% x x x x x x x
Eye movement disorder Eye movement disorder x x x x x
Eye rolling x x x
Oligomenorrhoea Oligomenorrhoea x x
Pain Pain x
Pain in extremity Pain in extremity 1% x x x x x
Pancreatic neoplasm Pancreatic neoplasm x
Paraesthesia Paraesthesia x
Pneumonia Pneumonia x x
Pneumonia aspiration Pneumonia aspiration x x x x
Pruritus Pruritus 1% x x x x x x x
Rales Rales x x
Respiratory tract infection Respiratory tract infection x x
Restless legs syndrome Restless legs syndrome x x
Rhabdomyolysis Rhabdomyolysis x x
Seborrhoeic dermatitis Seborrhoeic dermatitis x x
Dandruff x
Convulsion Convulsion x x x x x x x x x
Sinusitis Sinusitis x x
Muscle spasms Muscle spasms x x x x x x x x x x
Cerebrovascular accident Cerebrovascular accident x x x x x x x x x
Completed suicide Suicide x x x x x x
Swelling Swelling x
Tetany Tetany x
Thirst Thirst x x
Onychomycosis Onychomycosis x x
Tinnitus Tinnitus x x
Tonsillitis Tonsillitis x x
Toothache Toothache 1% x x x x
Torsade de pointes Torsade de pointes x x
Torticollis Torticollis x x x x
Trismus Trismus x x x x x x x x
Erythema Erythema x x
Redness x
Pollakiuria Pollakiuria x x
Urinary tract infection Urinary tract infection x x x x x x
Urticaria Urticaria x x x
Venous thrombosis Venous thrombosis x
Ventricular fibrillation Ventricular fibrillation x x
Ventricular tachycardia Ventricular tachycardia x x
Vertigo Vertigo x x x
Viral infection Viral infection 1% x
Weight decreased Weight decreased 1% x x x
Wheezing Wheezing x x
Choreoathetosis Choreoathetosis x x
Chills Chills x x
Polydipsia Polydipsia x x
Ventricular arrhythmia Ventricular arrhythmia x
Akinesia Akinesia x x
Stupor Stupor x
Depressed level of consciousness Stupor x
Depressed level of consciousness x x
Photophobia Photophobia x x
Oculogyric crisis Oculogyric crisis 0% - 2% x x
Oculogyration 0% x x x x x x
Oedema peripheral Oedema peripheral x x x x
Breast engorgement Breast engorgement x x x x
Hypokinesia Hypokinesia x x x x x x
Breast discharge Breast discharge x x x x x
Cogwheel rigidity Cogwheel rigidity x x x x x x x x x x
Generalised oedema Generalised oedema x x
Fluid retention Generalised oedema x x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x x
Injection site reaction Injection site reaction x
Muscular weakness Muscular weakness x x
Opisthotonus Opisthotonus x x x x
Emprosthotonus x
Electrocardiogram QT prolonged Electrocardiogram QT prolonged x x
Electrocardiogram QT corrected interval prolonged 3% x
Aspartate aminotransferase increased Aspartate aminotransferase increased x x
Alanine aminotransferase increased Alanine aminotransferase increased 1% x x x
Skin discolouration Skin discolouration x x
Dry skin Dry skin x x
Joint swelling Joint swelling x x
Drug withdrawal syndrome Drug withdrawal syndrome x x
Lacrimation increased Lacrimation increased x x
Endophthalmitis Ocular hyperaemia x x
Ocular hyperaemia Ocular hyperaemia x x
Menstruation irregular Menstruation irregular x x x x x x x
Joint stiffness Joint stiffness x x x
Dandruff Dandruff x
Vaginal discharge Vaginal discharge x x
Malaise Malaise x x
Discomfort Malaise x x
Ill-defined disorder Malaise x x
Posture abnormal Posture abnormal x x
Muscle twitching Muscle twitching x x x x x x x
Teratogenicity Teratogenicity x
Disturbance in attention Disturbance in attention x x
Blunted affect Blunted affect x x
Bradykinesia Bradykinesia x x x x x x x
Anorgasmia Anorgasmia x x
Oropharyngeal spasm Oropharyngeal spasm x x
Tongue spasm Tongue spasm x x
Tongue paralysis Tongue paralysis 0% - 3% 0% x x x x
Muscle contractions involuntary Muscle contractions involuntary x x
Ejaculation delayed Ejaculation inhibited x
Small intestinal obstruction Small intestinal obstruction x x
Galactorrhoea Galactorrhoea 0% - 4% 0% x x x x x x x
Chest discomfort Chest discomfort x x
Ejaculation disorder Ejaculation disorder x x
Hepatic enzyme increased Hepatic enzyme increased x x
Throat tightness Throat tightness x x x x x x
Gastrointestinal obstruction Gastrointestinal obstruction x x x x x x
Menstruation delayed Menstruation delayed x x x
Pulmonary congestion Pulmonary congestion x x
Respiratory tract congestion Pulmonary congestion x x
Respiratory tract congestion x x
Erectile dysfunction Erectile dysfunction x x x x x
Breast tenderness Breast tenderness x x
Conduction disorder Conduction disorder x x
Facial spasm Facial spasm x x
Dry eye Dry eye 0% x x x
Induration Induration x x x
Risus sardonicus Risus sardonicus x
Vision blurred Vision blurred 0% - 3% 0% - 1% x x x x x x
Emprosthotonus Emprosthotonus x
Initial insomnia Initial insomnia x x
Middle insomnia Middle insomnia x x
Retrograde ejaculation Retrograde ejaculation x x x x
Suicidal ideation Suicidal ideation 1% x
Masked facies Masked facies x
Parkinsonian gait Parkinsonian gait x x x
Electrocardiogram T wave abnormal Electrocardiogram T wave abnormal 1% x
Transaminases increased Transaminases increased x x
Pruritus generalised Pruritus generalised x
Respiratory distress Respiratory distress x
Blood pressure increased Blood pressure increased 1% x
Sudden death Sudden death, cause unknown x x
Pleurothotonus Pleurothotonus x x
Electrocardiogram T wave inversion Electrocardiogram T wave inversion 1% x
Coordination abnormal Coordination abnormal x x
Face oedema Face oedema x x
Altered state of consciousness Depressed level of consciousness x x
Sexual dysfunction Sexual dysfunction x x x
Gait disturbance Gait disturbance x x
Balance disorder Balance disorder x x
Blood cholesterol increased Blood cholesterol increased x x
Stillbirth Stillbirth x
Ear infection Ear infection x x
Acne Acne x
Haematocrit decreased Haematocrit decreased x x
Blood prolactin increased Increased prolactin level x
Serum prolactin increased x x x x x x x x x x
White blood cell count decreased White blood cell count decreased x x
Infestation Infestation NOS x x x x x x x
Blood creatine phosphokinase increased Blood creatine phosphokinase increased 1% x x x
Unresponsive to stimuli Unresponsive to stimuli x x
Blood testosterone decreased Serum testosterone decreased x
Insulin C-peptide increased Insulin C-peptide increased 1% x
Hyperkeratosis Hyperkeratosis x x
Muscle tightness Muscle tightness x x x
Breast discomfort Breast discomfort x x x x
Cerebral ischaemia Cerebral ischaemia x
Insomnia Insomnia x x x x
Musculoskeletal stiffness Musculoskeletal stiffness x x x x x x x
Injection site pain Pain during injection x
Parkinsonian rest tremor Parkinsonian rest tremor x
Glabellar reflex abnormal Glabellar reflex abnormal x x
Diabetic hyperglycaemic coma Diabetic coma x x
Diabetic coma Diabetic coma x x
Postural orthostatic tachycardia syndrome Postural orthostatic tachycardia syndrome x x x
Nuchal rigidity Nuchal rigidity x x
Acarodermatitis Acarodermatitis x x
Rash papular Rash papular x x
Dysphonia Dysphonia x x
Head titubation Head titubation x x
Waist circumference increased Waist circumference increased x
Embolism venous Venous thromboembolism x
Breast enlargement Breast enlargement x x
Eosinophil count increased Eosinophil count increased x x
Oromandibular dystonia Oromandibular dystonia x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

PALIPERIDONE / INVEGA

Side effects:58
Source:FDA

PALIPERIDONE / INVEGA

Side effects:60
Source:FDA

paliperidone / Invega

Side effects:61
Source:FDA

PALIPERIDONE / INVEGA

Side effects:104
Source:Health Canada

PALIPERIDONE

Side effects:105
Source:FDA Structured Product Label

paliperidone

Side effects:106
Source:FDA Structured Product Label

paliperidone

Side effects:117
Source:FDA Structured Product Label

paliperidone

Side effects:147
Source:FDA Structured Product Label

paliperidone / paliperidone

Side effects:271
Source:EMA

INVEGA / Invega, Modified release tablet

Side effects:289
Source:Medsafe

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label