Search results :

Everolimus

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: L01XE10, L04AA18

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Gastrointestinal disorder Gastrointestinal disorder 50.2% x x x x x x x
Infection Infection 0.7% - 95% x x x x x x x
Infestation Infestation NOS 43.6% x x x x x x x
Nervous system disorder Nervous system disorder 35.3% x x x x x x
Angiopathy Angiopathy 23.7% x x x x x x x
White blood cell count decreased White blood cell count decreased 2% - 43% 0% - 13% x x x
Blood calcium decreased Calcium low 0.5% - 37% 0% - 12% x
Lymphocyte count decreased Lymphocyte count decreased 2% - 51% 0% - 28% x x
Asthenia Asthenia very common, 0% - 19% 0% - 20% x x x
Fatigue common — 0% - 45% 0% - 27% x x x x x
Diarrhoea Diarrhoea common — 0% - 50% 0% - 25% x x x x x x x
Headache Headache common — 0% - 30% 0% - 15% x x x x x x
Hypercholesterolaemia Hypercholesterolaemia very common, 0% - 85% 0% - 46% x x x x x
Hyperglycaemia Hyperglycaemia very common, 25% x x x x x
Fasting hyperglycaemia 0% - 14% 0% - 8% x
Hyperlipidaemia Hyperlipidaemia common — 9.54% - 52.2% x x x x x x
Oedema peripheral Oedema peripheral very common, 0% - 44.9% 0% - 8% x x x x x x
Haemoglobin decreased Haemoglobin decreased 1% - 92% 1% - 79% x x
Blood glucose increased Glucose increased 1% - 57% 0% - 25% x x
Nausea Nausea common — 0% - 32% 0% - 33% x x x x x x x
Hypertension Hypertension common — 0% - 47.4% 0% - 6% x x x x x x x
Blood potassium decreased Potassium low 4% - 23% 0% - 5% x x
Tremor Tremor 12% x
Hypokalaemia Hypokalaemia common — 2.07% - 12.9% x x x x
Diabetes mellitus Diabetes mellitus common — 0% - 24.9% 0% - 0.5% x x x x x x
Body temperature increased Body temperature increased common — 0% - 31% 0% - 18% x x x x x x
Abdominal pain Abdominal pain common — 0% - 36% 1% - 32% x x x x x x x
Gastrointestinal pain Abdominal pain common — 0% - 36% 1% - 32% x x x x x x x
Pruritus Pruritus common — 0% - 21% 0% - 13% x x x x x
Blood phosphorus decreased Phosphate low 0% - 40% 0% - 14% x x
Liver function test abnormal Liver function test abnormal 9.96% x x
Pain Pain very common, 3.27% - 15.4% x x x
Weight decreased Weight decreased common — 0% - 28% 0% - 11% x x x x
Vomiting Vomiting common — 0% - 29% 0% - 21% x x x x x x x
Stomatitis Stomatitis common — 0% - 78% 0% - 26% x x x x x x x
Mouth ulceration common — 1.24% - 9.39% x x x x x x
Hyponatraemia Sodium decreased 1% - 16% 1% - 16% x
Hyponatraemia x
Anxiety Anxiety very common, 0% - 21% 0% - 3% x x x
Blood creatinine increased Creatinine increased 0% - 50% 0% - 34% x x
Blood creatinine increased common x x x
Serum creatinine increased x
Blood alkaline phosphatase increased Phosphatase alkaline increased 0% - 74% 0% - 66% x x
Blood alkaline phosphatase increased x
Hepatitis C Hepatitis C 7.88% x
Dyspnoea Dyspnoea common — 0.5% - 20% 0% - 7% x x x x x x
Blood albumin decreased Albumin low 1% - 13% 0% - 8% x
Insomnia Insomnia uncommon — 0% - 26.9% 0% - 8% x x x x x x
Mouth ulceration Mouth ulceration common — 1.24% - 9.39% x x x x x x
Constipation Constipation common — 0% - 42.9% 0% - 13% x x x x x
Cough Cough common — 0% - 25% 0% - 13% x x x x x x
Arthralgia Arthralgia common, 0% - 15% 0% - 7% x x x x x
Musculoskeletal discomfort Arthralgia common, 0% - 15% 0% - 7% x x x x x
Myalgia common, 1.66% - 7.17% x x x
Dysmenorrhoea Dysmenorrhoea 6% x
Metrorrhagia Metrorrhagia 6% x
Menorrhagia Menorrhagia common, 6% - 10% x x x
Decreased appetite Decreased appetite common — 0% - 30% 0% - 18% x x x x x
Anorexia x x
Embolism Thromboembolic event very common, 1.24% - 12.2% x
Alopecia Alopecia common x x x x
Anaemia Anaemia common — 0% - 61% 0% - 49% x x x x x x x
Cellulitis Cellulitis common, 29% x x x x
Chest pain Chest pain 5% x x
Chest discomfort x
Dysphagia Dysphagia common, 4% x x x x
Dehydration Dehydration common x x x x
Dysgeusia Dysgeusia common — 0% - 19% 0% - 5% x x x x
Dyspepsia Dyspepsia common x x x
Epistaxis Epistaxis common — 0% - 22% 0% - 1% x x x x x x
Dermatitis Rash common — 0% - 59% 0% - 19% x x x x x x x
Rash Rash common — 0% - 59% 0% - 19% x x x x x x x
Fatigue Fatigue common — 0% - 45% 0% - 27% x x x x x
Flatulence Flatulence common x x x
Gastritis Gastritis common x x
Gingivitis Gingivitis common x
Haemorrhage Haemorrhage common, 3% x x x x
Haemoglobin Haemorrhage common, 3% x x x x
Haemorrhoids Haemorrhoids 5% x x
Hypertriglyceridaemia Hypertriglyceridaemia common, 0% - 52% 0% - 15% x x x x x
Blood triglycerides increased Hypertriglyceridaemia common, 0% - 52% 0% - 15% x x x x x
Blood triglycerides increased x
Hypocalcaemia Hypocalcaemia common x x
Irritability Irritability common x x
Leukopenia Leukopenia common, 0% - 37% 0% - 21% x x x x x x x
Lymphopenia Lymphopenia common, 0% - 20% 0% - 8% x x x x
Nail disorder Nail disorder common, 0% - 22% 0% - 2% x x x
Nasopharyngitis Nasopharyngitis common, 0% - 25% 0% - 13% x x x x
Rhinorrhoea 3% x x
Neutropenia Neutropenia common, 0% - 46% 0% - 41% x x x x x
Otitis media Otitis media common, 6% x x x
Ovarian cyst Ovarian cyst common x x
Paraesthesia Paraesthesia 5% x x
Pharyngitis Pharyngitis common x x
Pneumonia Pneumonia uncommon — 0.5% - 17% 0% x x x x x x x
Infectious pneumonitis x x
Renal failure Renal failure common, 3% x x x x
Renal impairment x
Pharyngitis streptococcal Pharyngitis streptococcal common, 0% - 10% 0% - 3% x x x
Sinusitis Sinusitis common x x x
Aphthous stomatitis Aphthous stomatitis common x x x
Thrombocytopenia Thrombocytopenia common — 0% - 19% 0% - 3% x x x x x x
Urinary tract infection Urinary tract infection common, 0% - 16% 0% - 6% x x x x x x
Dry mouth Dry mouth common, 0% - 11% 0% - 4% x x x
Hypophosphataemia Hypophosphataemia common, 0% - 49% 0% - 15% x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased common x x x
Alanine aminotransferase increased Alanine aminotransferase increased common x x x x
Dry skin Dry skin common, 0% - 13% 0% - 6% x x x x
Viral diarrhoea Viral diarrhoea common x x
Menstruation irregular Menstruation irregular uncommon — 6% - 10% x x x x
Oral pain Oral pain common x x x
Myalgia Myalgia common, 1.66% - 7.17% x x x
Dermatitis acneiform Dermatitis acneiform common, 3% x x x x
Tongue ulceration Tongue ulceration common x x
Lung infiltration Lung infiltration common x x
Skin exfoliation Skin exfoliation common x
Menstruation delayed Menstruation delayed common x x
Mucosal inflammation Mucosal inflammation common x x x
Alveolitis Alveolitis common x x
Acne Acne common, 0% - 22% 0% - 5% x x x x
Pulmonary alveolar haemorrhage Pulmonary alveolar haemorrhage common x x
Blood luteinising hormone increased Blood luteinising hormone increased common x x
Gonadotropic luteinizing hormone increased x
Blood lactate dehydrogenase increased Blood lactate dehydrogenase increased common x x
Pulmonary toxicity Pulmonary toxicity common x x
Vaginal haemorrhage Vaginal haemorrhage common, 8% x x x
Pleural effusion Pleural effusion 1.83% - 25.4% x x x x
Skin lesion Skin lesion common, 4% x x
Erythema Erythema uncommon — 4% x x x x
Eyelid oedema Eyelid oedema common, 4% x x
Onychoclasis Onychoclasis common, 4% x x
Oropharyngeal pain Oropharyngeal pain common, 0% - 11% 0% - 6% x x x x
Pain in extremity Pain in extremity 0% - 14% 0% - 6% x x
Tachycardia Tachycardia common, 2.04% - 7.09% x x x
Proteinuria Proteinuria uncommon — 0.83% - 9.12% x x x x x x
Protein urine present Proteinuria uncommon — 0.83% - 9.12% x x x x x x
Gastroenteritis Gastroenteritis 1% - 10% 0% - 3% x x
Chills Chills 4% x x
Laryngeal pain Pharyngolaryngeal pain 4% x
Dizziness Dizziness 0% - 12% 0% - 7% x x
Syncope x
Blood potassium increased Potassium increased 0% - 7% 0.5% - 10% x
Hepatic enzyme abnormal Hepatic enzyme abnormal 1.87% - 9.96% x x
Lymphocele Lymphocele 0% - 7.66% x x x
Incisional hernia Incisional hernia common, 1.1% - 6.94% x x x
Malaise Malaise 0.5% - 45% 0.5% - 27% x x
Discomfort Malaise 0.5% - 45% 0.5% - 27% x x
Feeling abnormal Malaise 0.5% - 45% 0.5% - 27% x x
Ill-defined disorder Malaise 0.5% - 45% 0.5% - 27% x x
Pain in jaw Pain in jaw 3% x
Platelet count decreased Platelet count decreased 0% - 45% 0% - 11% x x
Rhinorrhoea Rhinorrhoea 3% x x
Amenorrhoea Amenorrhoea rare — common x x x x
Amenorrhea secondary x x
Erectile dysfunction Erectile dysfunction common, 1.22% - 5.38% x x x
Thrombosis Thrombosis common, 1.1% - 2.19% x x x
Dyspnoea exertional Dyspnoea exertional 0.5% - 20% 0% - 7% x
Conjunctivitis Conjunctivitis uncommon, 2% x x x
Angioedema Angioedema postmarketing — 1.22% - 5.02% x x x x x x
Back pain Back pain 0% - 15% 0% - 11% x x
Oedema Oedema 0.5% - 39% 0% - 12% x x x
Respiratory tract infection Respiratory tract infection 1% - 31% 0% - 23% x
Blood bilirubin increased Blood bilirubin increased 1% - 10% 0% - 14% x x
Interstitial lung disease Interstitial lung disease common, 0.408% - 2.51% x x x x x
Pancytopenia Pancytopenia uncommon — 0% - 3.67% x x x x x
Renal failure acute Acute respiratory failure 0.7% x
Renal failure acute uncommon, 0.4% x x x x
Acute respiratory failure Acute respiratory failure 0.7% x
Pericardial effusion Pericardial effusion 0.365% - 39.8% x x
Pancreatitis Pancreatitis postmarketing — 0% - 1.43% x x x
Aggression Aggression uncommon, 0% - 21% 0% - 3% x x x
Flushing Flushing uncommon x
Glossodynia Glossodynia uncommon x x
Glossitis Glossitis uncommon x x x
Cardiac failure congestive Cardiac failure congestive uncommon, 1% x x x x
Haemoptysis Haemoptysis uncommon x x
Herpes zoster Herpes zoster uncommon x x x
Hypersensitivity Hypersensitivity uncommon, 3% x x x x x
Jaundice Jaundice uncommon, 0% - 2.07% x x
Opportunistic infection Opportunistic infection uncommon x x
Pulmonary embolism Pulmonary embolism postmarketing, uncommon x x x x x
Rhabdomyolysis Rhabdomyolysis uncommon x
Deep vein thrombosis Deep vein thrombosis uncommon, 1% x x x x x
Rash macular Rash macular uncommon x x
Rash erythematous Rash erythematous uncommon x x
Gingival pain Gingival pain uncommon x x
Sepsis Sepsis uncommon x x x x x x
Cheilitis Lip ulceration uncommon x x
Lip pain Lip ulceration uncommon x x
Lip ulceration Lip ulceration uncommon x x
Bronchitis viral Bronchitis viral uncommon x x
Rash maculo-papular Rash maculo-papular uncommon x x
Non-cardiac chest pain Non-cardiac chest pain uncommon x x
Rash generalised Rash generalised uncommon x x
Blood follicle stimulating hormone increased Blood follicle stimulating hormone increased uncommon x x
Ageusia Ageusia uncommon x x
Renal tubular necrosis Renal tubular necrosis 0% - 5.47% x x
Migraine Migraine 0% - 30% 0% - 15% x x
Impaired healing Impaired healing rare — 1% x x x x x x
Productive cough Productive cough 0% - 25% 0% - 13% x
Hepatitis Hepatitis uncommon, 0.358% - 2.07% x x
Coagulopathy Coagulopathy uncommon, 0% - 0.733% x x
Wound complication Wound complication uncommon, 0% - 0.373% x x
Aplasia pure red cell Aplasia pure red cell rare, uncommon x x
Acute respiratory distress syndrome Acute respiratory distress syndrome rare, uncommon x x
Pancreatitis acute Pancreatitis acute postmarketing x
Cholecystitis Cholecystitis postmarketing x
Cholelithiasis Cholelithiasis postmarketing x
Infertility male Infertility male postmarketing x
Cervicobrachial syndrome Reflex sympathetic dystrophy postmarketing x
Complex regional pain syndrome Reflex sympathetic dystrophy postmarketing x
Abdominal distension Abdominal distension x
Acidosis Acidosis x
Angina pectoris Angina pectoris x
Ascites Ascites x
Aspergillus infection Aspergillosis x x
Atelectasis Atelectasis x
Pneumothorax Atelectasis x
Atrial fibrillation Atrial fibrillation x
Bacteraemia Bacteraemia x
Mental disorder Mental disorder x x x x x x
Breast cancer Breast cancer x
Breast disorder Breast disorder x x x x x x
Bronchospasm Bronchospasm x
Bronchitis Bronchitis x
Candida infection Candida infection x x x
Oral candidiasis x
Oral candidiasis Oral candidiasis x
Basal cell carcinoma Basal cell carcinoma x
Squamous cell carcinoma Squamous cell carcinoma x
Connective tissue disorder Connective tissue disorder x x x x x x x
Cytomegalovirus infection Cytomegalovirus infection x
Sudden death Sudden death x
Dermatitis exfoliative Dermatitis exfoliative x
Dysuria Dysuria x
Endocrine disorder Endocrine disorder x x x
Eye disorder Eye disorder x x x
Fibrosis Fibrosis x
Folliculitis Folliculitis x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease x
Gingival hypertrophy Gingival hypertrophy x
Glioblastoma Glioblastoma x
Glomerulonephritis Glomerulonephritis x
Gout Gout x
Hallucination Hallucination x
Cardiac arrest Cardiac arrest x
Cardiac disorder Cardiac disorder x x x x x
Cardiac failure Cardiac failure x
Haematemesis Haematemesis x
Blood disorder Blood disorder x
Haematoma Haematoma x
Haematuria Haematuria x
Hemiparesis Hemiparesis x
Haemolytic uraemic syndrome Haemolytic uraemic syndrome x x
Hepatitis B Hepatitis B x x
Hepatitis B reactivation x x x
Chronic hepatitis Chronic hepatitis x
Herpes virus infection Herpes virus infection x
Hirsutism Hirsutism x
Histiocytosis Histiocytosis x
Hydronephrosis Hydronephrosis x
Hypercalcaemia Hypercalcaemia x
Hyperhidrosis Hyperhidrosis x
Hyperkalaemia Hyperkalaemia x
Hyperparathyroidism Hyperparathyroidism x
Hypertensive crisis Hypertensive crisis x
Hypertrichosis Hypertrichosis x
Hypoaesthesia Hypoaesthesia x
Hypoglycaemia Hypoglycaemia x x
Hypotension Hypotension x
Immune system disorder Immune system disorder x x x
Inflammation Inflammation x
Influenza Influenza x
Seborrhoeic keratosis Seborrhoeic keratosis x
Lethargy Lethargy x
Leukocytosis Leukocytosis x
Cirrhosis alcoholic Cirrhosis alcoholic x
Liver disorder Liver disorder x
Hepatocellular injury Liver disorder x
Foetor hepaticus Liver disorder x
Lymphoma Lymphoma x x x
Non-Hodgkin's lymphoma Lymphoma x x x
Lymphoproliferative disorder Lymphoproliferative disorder x x x
X-linked lymphoproliferative syndrome Lymphoproliferative disorder x x x
Mediastinal disorder Mediastinal disorder x x x x x x x
Musculoskeletal pain Musculoskeletal pain x
Fungal infection Fungal infection x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Nasal congestion Nasal congestion x
Neoplasm Neoplasm x x
Tubulointerstitial nephritis Nephritis interstitial x
Nephrosclerosis Nephrosclerosis x
Neuralgia Neuralgia x
Night sweats Night sweats x
Osteomyelitis Osteomyelitis x
Osteonecrosis Osteonecrosis x
Osteopenia Osteopenia x
Osteoporosis Osteoporosis x
Palpitations Palpitations x
Peritonitis Peritonitis x
Polyuria Polyuria x
Urine output increased Polyuria x
Alveolar proteinosis Alveolar proteinosis x x
Pulmonary oedema Pulmonary oedema x
Thrombotic thrombocytopenic purpura Thrombotic thrombocytopenic purpura common, 0% - 1.46% x x x
Pyelonephritis Pyelonephritis common, 0% - 2.19% x x x
Pyuria Pyuria x
Rhinitis Rhinitis 0% - 25% 0% - 13% x
Kaposi's sarcoma Kaposi's sarcoma x
Convulsion Convulsion x
Neoplasm skin Neoplasm skin x
Muscle spasms Muscle spasms 0% - 10% 0% - 4% x x
Spondylitis Spondylitis x
Spondyloarthropathy Spondylitis x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Tinea pedis Tinea pedis x
Onychomycosis Onychomycosis x
Upper respiratory tract infection Upper respiratory tract infection 0% - 11% 0% - 5% x x x x x
Urethritis Urethritis x
Urethritis noninfective Urethritis x
Pollakiuria Pollakiuria x
Micturition urgency x
Urethral disorder Urinary tract disorder x x x x x x x
Urinary tract disorder Urinary tract disorder x x x x x x x
Viral infection Viral infection x x x
Vitamin B12 deficiency Vitamin B12 deficiency x
Wheezing Wheezing x
Wound infection Wound infection x x x
Wound Wound x
Xeroderma Xeroderma 0% - 13% 0% - 6% x
Urinary retention Urinary retention x
Hepatic failure Hepatic failure x
Micturition urgency Micturition urgency x
Agitation Agitation x x
Cataract Cataract x
Benign neoplasm Benign neoplasm x
Lower respiratory tract infection Lower respiratory tract infection x
Blood urea increased Blood urea increased x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Fluid retention x
Scrotal oedema Scrotal oedema x
Hypogonadism male Hypogonadism male uncommon, 0% - 0.733% x x
Hypomagnesaemia Hypomagnesaemia x
Muscular weakness Muscular weakness x
Sinus congestion Sinus congestion x
Joint swelling Joint swelling x
Malnutrition Malnutrition x x x x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x x x x x x
Erythropenia Erythropenia x
Abdominal pain upper Abdominal pain upper x
Chest discomfort Chest discomfort x
Hepatic enzyme increased Hepatic enzyme increased x
Renal vein thrombosis Renal vein thrombosis x
Iron deficiency Iron deficiency x
Activated partial thromboplastin time prolonged Activated partial thromboplastin time prolonged x
Blood testosterone decreased Testosterone low uncommon, 0% - 0.733% x x
Dyslipidaemia Dyslipidaemia x
Disease progression Disease progression x
Wound dehiscence Wound dehiscence x
Seroma Seroma x
Hepatobiliary disease Hepatobiliary disease x x x x
Glomerulonephropathy Glomerulonephropathy x
Metastatic malignant melanoma Metastatic melanoma x
Azotaemia Uraemic syndrome common, 0% - 1.46% x
Lymphorrhoea Lymphorrhoea x
Renal artery thrombosis Renal artery thrombosis x
Oral herpes Oral herpes x
Vision blurred Vision blurred x
Hepatic cancer Hepatic cancer x
Hepatocellular carcinoma x
Skin papilloma Skin papilloma x
Hepatic artery thrombosis Hepatic artery thrombosis x
Renal haemorrhage Renal haemorrhage x
Bladder pain Bladder spasm x
Bladder spasm Bladder spasm x
Transaminases increased Transaminases increased x
Perirenal haematoma Perirenal haematoma x
Pruritus generalised Pruritus generalised 0% - 21% 0% - 13% x
Respiratory distress Respiratory distress x
Lymphadenopathy Lymphadenopathy x
Blood cholesterol increased Blood cholesterol increased x
Nephropathy toxic Nephrotoxicity x
Menopausal symptoms Hot flush x
Hot flush Hot flush x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Chronic hepatic failure End stage liver disease x
Lymphangioleiomyomatosis Lymphangioleiomyomatosis x x
Thrombocytosis Thrombocytosis x
Lipids increased Lipids increased x
Graft loss Graft loss x
Graft thrombosis Graft thrombosis x x
Colorectal cancer metastatic Colorectal cancer metastatic x
BK virus infection BK virus infection x
Incision site pain Incision site pain x
Perinephric collection Perinephric collection x
Ileus Ileus x
Epigastric discomfort Epigastric discomfort x
Renal impairment Renal impairment x
Procedural pain Procedural pain x
Embolism venous Venous thromboembolism x x
Localised intraabdominal fluid collection Localised intraabdominal fluid collection x
Hepatocellular carcinoma Hepatocellular carcinoma x
Thrombotic microangiopathy Thrombotic microangiopathy common, 0% - 1.46% x x
Somnolence Somnolence x
Leukocytoclastic vasculitis Leukocytoclastic vasculitis x
Infection reactivation Infection reactivation x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

CERTICAN / Certican, Tablet

Side effects:71
Source:Medsafe

everolimus / CERTICAN

Side effects:82
Source:medicines.org.au

everolimus / everolimus

Side effects:100
Source:EMA

everolimus / everolimus

Side effects:108
Source:EMA

everolimus / AFINITOR

Side effects:137
Source:medicines.org.au

EVEROLIMUS

Side effects:147
Source:FDA Structured Product Label

EVEROLIMUS

Side effects:243
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label