Exemestane

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Flushing def Flushing def 21.2% x x x x
Menopausal symptoms def Hot flush def 21.2% x x x x x x x
Hot flush def Hot flush def 21.2% x x x x x x x
Asthenia def Fatigue def 16.1% x x x x x x x
Asthenia def x x x x x x x
Weakness def x x x x x
Fatigue def Fatigue def 16.1% x x x x x x x
Arthralgia def Arthralgia def 14.6% x x x x x x x
Musculoskeletal discomfort Arthralgia def 14.6% x x x x x x x
Myalgia def x x x x x
Headache def Headache def 13.1% x x x x x x x
Insomnia def Insomnia def 12.4% x x x x x x x
Hyperhidrosis def Sweating def 11.8% x x x x x x x
Sweating increased 11.8% x x x x x x
Hypertension def Hypertension def 9.8% x x x x x x x
Dizziness def Dizziness def 9.7% x x x x x x x
Pain def Pain def 8.6% - 9% x x x x x x x
Pain in extremity def Pain in extremity def 9% x x x x
Back pain def Back pain def 8.6% x x x x x x x
Nausea def Nausea def 8.5% x x x x x x x
Osteoarthritis def Osteoarthritis def 5.9% x x x x
Visual impairment def Visual disturbance 5% x x x x
Erythema multiforme def Erythema multiforme def postmarketing x
Hepatitis def Hepatitis def postmarketing x x x
Erythema def Erythema def postmarketing x
Hepatitis cholestatic Hepatitis cholestatic postmarketing x x
Abdominal pain def Abdominal pain def x x x x x x x
Gastrointestinal pain def Abdominal pain def x x x x x x x
Alopecia def Alopecia def x x x x x x x
Angina pectoris def Angina pectoris def x x x x
Decreased appetite Anorexia def x x x x x x x
Anxiety def Anxiety def x x x x x x x
Bronchitis def Bronchitis def x x x x x x
Cardiovascular disorder def Cardiovascular disorder def x x x x
Carpal tunnel syndrome def Carpal tunnel syndrome def x x x
Chest pain def Chest pain def x x x x x x
Confusional state def Confusional state def x x x x x x
Feeling abnormal Confusional state def x x x x x x
Constipation def Constipation def x x x x x x x
Cough def Cough def x x x x x x x
Dermatitis def Dermatitis def x x x x
Rash def x x x x x x
Diarrhoea def Diarrhoea def x x x x x x x
Dyspepsia def Dyspepsia def x x x x x x
Dyspnoea def Dyspnoea def x x x x x x x
Oedema def Oedema def x x x x x x
Endometrial hyperplasia def Endometrial hyperplasia def x x x
Rash def Rash def x x x x x x
Body temperature increased def Body temperature increased def x x x x x x
Pathological fracture def Pathological fracture def x x x x x x
Genital disorder female def Genital disorder female def x x x x
Cardiac failure def Cardiac failure def x x x x
Haemorrhage def Haemorrhage def x x
Haemoglobin def Haemorrhage def x x
Dysphonia def Hoarseness def x
Hypercholesterolaemia def Hypercholesterolaemia def x
Hyperplasia def Hyperplasia def x x x
Hypertrichosis def Hypertrichosis def x
Hypoaesthesia def Hypoaesthesia def x x x x x
Infarction def Infarction def x x x x x x
Infection def Infection def x x x x x x x
Influenza def Influenza def x x x x x x x
Ischaemia def Ischaemia def x x x x
Lymphoedema def Lymphoedema def x x x x x x
Lymphopenia def Lymphopenia def x
Multi-organ failure def Multi-organ failure def x x x x x x
Muscle spasms def Cramp muscle def x x x x x
Musculoskeletal disorder def Musculoskeletal disorder def x x x x
Myocardial infarction def Myocardial infarction def x x x x x x
Acute coronary syndrome def Myocardial infarction def x x x x x x
Neoplasm def Neoplasm def x x x x x x x
Nervous system disorder def Nervous system disorder def x x x x
Opportunistic infection def Opportunistic infection def x
Osteochondrosis def Osteochondrosis def x x
Osteoporosis def Osteoporosis def x x x x x
Paraesthesia def Paraesthesia def x x x x x x
Pharyngitis def Pharyngitis def x x x x x x
Polyp def Polyp def x x x
Pruritus def Pruritus def x x x x x x
Pulmonary embolism def Pulmonary embolism def x
Respiratory tract infection def Respiratory tract infection def x x x x x x
Rhinitis def Rhinitis def x x x x x x
Sinusitis def Sinusitis def x x x x x x
Gastric ulcer def Gastric ulcer def x x x
Cerebrovascular accident def Cerebrovascular accident def x x x x
Tendonitis def Tendonitis def x
Embolism def Thromboembolism def x x x
Thromboembolic event x
Embolus def x
Embolism venous Thromboembolism def x x x
Thrombosis def Thrombosis def x
Ulcer def Ulcer def x x x
Upper respiratory tract infection def Upper respiratory tract infection def x x x x x x
Urinary tract infection def Urinary tract infection def x x x x x x x
Venous thrombosis def Venous thrombosis def x
Viral infection def Viral infection def x
Vomiting def Vomiting def x x x x x x x
Weight increased def Weight increased def x x x x x x x
Oedema peripheral def Oedema peripheral def x x x
Leg edema x x x x x
Deep vein thrombosis def Deep vein thrombosis def x
Gamma-glutamyltransferase increased def Gamma-glutamyltransferase increased def x
Vaginal haemorrhage def Bleeding vaginal def x
Vaginal haemorrhage def x x
Myocardial ischaemia def Myocardial ischaemia def x x x x
Bone pain def Bone pain def x x x x x x
Trigger finger def Trigger finger def x x
Malaise def Sickness x x x x
Myalgia def Myalgia def x x x x x
Increased appetite Increased appetite x x x x x x x
Vulvovaginal dryness Vaginal dryness def x
Neuropathy peripheral def Neuropathy def x x x x
Osteoporotic fracture def Osteoporotic fracture def x x x x
Acne def Acne def x
Arterial disorder def Arterial disorder def x x x x x x
Tumour pain def Tumour pain def x x x x x x
Organ failure Organ failure x x x x x x
Death Death x x x x x x
Coronary artery disease def Coronary artery disease def x x x x x x
Indication Labels
Adjuvant therapy def x x x x
Breast cancer def x x x x x x x
Neoplasm malignant def x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: L02BG06

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. Exemestane : 60 side effects (BC Cancer)
  2. EXEMESTANE / AROMASIN : 75 side effects (Health Canada)
  3. EXEMESTANE / AROMASIN : 56 side effects (Drugs@FDA)
  4. exemestane tablets / Aromasin : 57 side effects (FDA MedWatch)
  5. EXEMESTANE / AROMASIN : 75 side effects (Drugs@FDA)
  6. EXEMESTANE : 88 side effects (FDA XML label)
  7. exemestane : 88 side effects (FDA XML label)