Exemestane
  
Side effects 
	
		
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| MedDRA Preferred Term | Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 
| Arthralgia | Arthralgia | very common, 8.6% - 28.8% | 28.8% | x | x | x | x | x | x | x | x | x | x | x | 
| Musculoskeletal discomfort | Arthralgia | very common, 8.6% - 28.8% | 28.8% | x | x | x | x | x | x | x | x | x | x | x | 
| Myalgia | very common, 5.5% - 2-33% | 4.1% | x | x |  |  | x |  | x | x | x | x | x | 
| Alopecia | Alopecia | common, 2-5% - 15.1% | 4.1% | x | x | x | x | x | x | x | x | x | x | x | 
| Arthritis | Arthritis | very common |  | x | x |  |  |  |  |  |  |  |  |  | 
| Asthenia | Fatigue | very common, 7.5% - 29% | 19.2% | x | x | x | x | x | x | x | x | x | x | x | 
| Asthenia | 6% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Fatigue | Fatigue | very common, 7.5% - 29% | 19.2% | x | x | x | x | x | x | x | x | x | x | x | 
| Musculoskeletal pain | Musculoskeletal pain | very common |  | x | x |  |  |  |  |  |  |  |  |  | 
| Joint stiffness | Joint stiffness | very common |  | x | x |  |  |  |  |  |  |  |  |  | 
| Menopausal symptoms | Hot flush | very common, 5% - 32.9% | 24.7% | x | x | x | x | x | x | x | x | x | x | x | 
| Hot flush | Hot flush | very common, 5% - 32.9% | 24.7% | x | x | x | x | x | x | x | x | x | x | x | 
| Pain | Pain | common, 2.8% - 13% |  | x | x | x | x | x | x | x | x | x | x | x | 
| Hyperhidrosis | Sweating | 6-19% |  |  |  |  |  | x |  |  |  |  |  |  | 
| Sweating increased | common — 4.5% - 17.8% | 20.6% | x | x | x | x |  | x | x | x | x | x | x | 
| Nausea | Nausea | very common, 5% - 18% | 16.4% | x | x | x | x | x | x | x | x | x | x | x | 
| Cardiovascular disorder | Cardiovascular disorder | 10.6% - 12.8% |  |  | x |  |  |  | x | x | x | x | x | x | 
| Cardiac disorder | Cardiac disorder | 10.6% - 12.8% |  |  | x |  |  |  |  |  |  |  |  |  | 
| Abdominal pain | Abdominal pain | common, 2.8% - 11% | 13.7% | x | x | x | x | x |  | x | x | x | x | x | 
| Gastrointestinal pain | Abdominal pain | common, 2.8% - 11% | 13.7% | x | x | x | x | x |  | x | x | x | x | x | 
| Insomnia | Insomnia | very common, 3.3% - 11-20% | 15.1% | x | x | x | x | x | x | x | x | x | x | x | 
| Anxiety | Anxiety | 4.1% - 11% | 5.5% |  |  | x | x | x |  | x | x | x | x | x | 
| Dyspnoea | Dyspnoea | 0.3% - 15% |  |  | x | x | x | x |  | x | x | x | x | x | 
| Depression | Depression | common, 5.6% - 13% | 6.9% | x | x | x | x |  |  | x | x | x | x | x | 
| Pain in extremity | Pain in extremity | very common, 6.4% - 9% |  | x | x |  |  |  |  | x | x | x | x | x | 
| Hypertension | Hypertension | 1.7% - 15.1% | 6.9% | x | x | x | x | x |  | x | x | x | x | x | 
| Dermatitis | Dermatitis | 8.2% | 1.4% |  |  |  |  |  |  | x | x | x | x | x | 
| Rash | common, 0% - 2-5% |  | x | x | x | x | x | x | x | x | x | x | x | 
| Dizziness | Dizziness | common, 3% - 8-13% | 9.6% | x | x | x | x | x |  | x | x | x | x | x | 
| Headache | Headache | very common, 1.5% - 8-19% | 4.1% | x | x | x | x | x | x | x | x | x | x | x | 
| Back pain | Back pain | very common, 2-5% - 8.6% |  | x | x | x | x | x | x | x | x | x | x | x | 
| Oedema peripheral | Oedema peripheral | 6% - 7% |  |  |  |  |  |  |  | x |  | x | x | x | 
| Leg edema | common, 1.4% - 7% |  | x | x | x | x |  |  | x | x | x | x | x | 
| Cough | Cough | 6% - 7% |  |  |  | x | x | x |  | x | x | x | x | x | 
| Oedema | Oedema | 2-5% - 7% | 6.9% |  |  | x | x | x |  | x | x | x | x | x | 
| Influenza like illness | Influenza-like symptoms | 5% - 6% |  |  |  | x | x | x |  | x | x | x | x | x | 
| Osteoarthritis | Osteoarthritis | very common, 4.5% - 5.9% |  | x | x |  |  |  |  | x | x | x | x | x | 
| Weight increased | Weight increased | 5.5% - 8% |  | x | x | x | x | x | x | x | x | x | x | x | 
| Myalgia | Myalgia | very common, 5.5% - 2-33% | 4.1% | x | x |  |  | x |  | x | x | x | x | x | 
| Decreased appetite | Anorexia | common, 5% - 6% |  | x | x | x | x | x |  | x | x | x | x | x | 
| Carpal tunnel syndrome | Carpal tunnel syndrome | common |  | x | x |  |  |  | x | x | x | x | x | x | 
| Constipation | Constipation | common, 0.8% - 8% |  | x | x | x | x | x |  | x | x | x | x | x | 
| Diarrhoea | Diarrhoea | common, 4% - 9.6% | 1.4% | x | x | x | x | x | x | x | x | x | x | x | 
| Dyspepsia | Dyspepsia | common, 2-5% |  | x | x | x | x | x | x | x | x | x | x | x | 
| Body temperature increased | Body temperature increased | 5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Multiple fractures | Fracture | common |  | x | x |  |  |  | x | x | x | x | x | x | 
| Fracture | Fracture | common |  | x | x |  |  |  | x | x | x | x | x | x | 
| Gastrointestinal disorder | Gastrointestinal disorder | common |  | x | x |  |  |  |  |  |  |  |  |  | 
| Dysphonia | Hoarseness | 5% |  |  |  |  |  | x |  |  |  |  |  |  | 
| Hypertrichosis | Hypertrichosis | 5% |  |  |  |  |  | x |  |  |  |  |  |  | 
| Osteoporosis | Osteoporosis | common, 7% |  | x | x |  |  | x | x | x | x | x | x | x | 
| Vomiting | Vomiting | common, 0.8% - 7% |  | x | x | x | x | x |  | x | x | x | x | x | 
| Visual impairment | Visual disturbance | 3.8% - 7% |  |  | x |  |  | x |  |  | x | x | x | x | 
| Bronchitis | Bronchitis | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Chest pain | Chest pain | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Infection | Infection | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Confusional state | Confusional state | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Feeling abnormal | Confusional state | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Rash | Rash | common, 0% - 2-5% |  | x | x | x | x | x | x | x | x | x | x | x | 
| Lymphoedema | Lymphoedema | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Pharyngitis | Pharyngitis | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Rhinitis | Rhinitis | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Sinusitis | Sinusitis | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Upper respiratory tract infection | Upper respiratory tract infection | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Urinary tract infection | Urinary tract infection | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Bone pain | Bone pain | 2-5% |  |  |  | x | x | x | x | x | x | x | x | x | 
| Muscle spasms | Cramp muscle | 3% |  | x |  |  |  | x | x | x | x | x | x | x | 
| Increased appetite | Increased appetite | 2.8% - 6% |  |  | x | x | x | x | x | x | x | x | x | x | 
| Vaginal haemorrhage | Vaginal haemorrhage | 0.6% - 4% |  | x | x |  |  | x |  | x |  |  |  |  | 
| Hepatitis | Hepatitis | postmarketing |  | x | x |  |  |  | x | x |  | x | x | x | 
| Hypersensitivity | Hypersensitivity | postmarketing |  | x | x |  |  |  | x |  |  |  | x | x | 
| Immune system disorder | Immune system disorder | postmarketing |  | x | x |  |  |  | x |  |  |  |  | x | 
| Nervous system disorder | Nervous system disorder | postmarketing |  |  |  |  |  |  | x | x | x | x | x | x | 
| Paraesthesia | Paraesthesia | postmarketing |  | x |  | x | x |  | x | x | x | x | x | x | 
| Pruritus | Pruritus | postmarketing, 2-5% |  | x | x | x | x | x | x | x | x | x | x | x | 
| Urticaria | Urticaria | postmarketing |  | x | x |  |  |  | x |  |  |  | x | x | 
| Hepatitis cholestatic | Hepatitis cholestatic | postmarketing |  | x | x |  |  |  | x |  |  | x | x | x | 
| Skin disorder | Unspecified disorder of skin and subcutaneous tissue | postmarketing |  | x | x |  |  |  | x |  |  |  |  | x | 
| Hepatobiliary disease | Hepatobiliary disease | postmarketing |  | x | x |  |  |  | x |  |  |  |  | x | 
| Acute generalised exanthematous pustulosis | Acute generalised exanthematous pustulosis | postmarketing |  |  |  |  |  |  | x |  |  |  | x | x | 
| Angina pectoris | Angina pectoris |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Mental disorder | Mental disorder |  |  | x | x |  |  |  |  |  |  |  |  |  | 
| Bone disorder | Bone disorder |  |  | x | x |  |  |  |  |  |  |  |  |  | 
| Neoplasm malignant | Neoplasm malignant |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Endometrial hyperplasia | Endometrial hyperplasia |  |  | x |  |  |  |  | x | x | x | x | x | x | 
| Erythema multiforme | Erythema multiforme |  |  |  |  |  |  |  |  | x |  |  |  |  | 
| Genital disorder female | Genital disorder female |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Cardiac failure | Cardiac failure |  |  | x |  |  |  |  | x | x | x | x | x | x | 
| Haemorrhage | Haemorrhage |  |  |  |  |  |  | x |  |  |  |  |  |  | 
| Haemoglobin | Haemorrhage |  |  |  |  |  |  | x |  |  |  |  |  |  | 
| Hypercholesterolaemia | Hypercholesterolaemia |  |  | x |  |  |  |  |  | x |  |  |  |  | 
| Hypoaesthesia | Hypoaesthesia |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Leukopenia | Leukopenia |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Multi-organ failure | Multi-organ failure |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Musculoskeletal disorder | Musculoskeletal disorder |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Myocardial infarction | Myocardial infarction |  |  | x |  | x | x |  | x | x | x | x | x | x | 
| Acute coronary syndrome | Myocardial infarction |  |  | x |  | x | x |  | x | x | x | x | x | x | 
| Neoplasm | Neoplasm |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Opportunistic infection | Opportunistic infection |  |  |  |  |  |  | x |  |  |  |  |  |  | 
| Osteochondrosis | Osteochondrosis |  |  |  |  |  |  |  | x |  | x | x | x | x | 
| Polyp | Polyp |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Pulmonary embolism | Pulmonary embolism |  |  |  |  |  |  |  |  | x |  |  |  |  | 
| Gastric ulcer | Gastric ulcer |  |  | x | x |  |  |  | x | x |  | x | x | x | 
| Cerebrovascular accident | Cerebrovascular accident |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Tendonitis | Tendonitis |  |  |  |  |  |  |  |  | x |  |  |  |  | 
| Thrombocytopenia | Thrombocytopenia |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Embolism | Thromboembolism |  |  | x |  |  |  |  | x | x | x | x | x | x | 
| Embolism venous | Thromboembolism |  |  | x |  |  |  |  | x | x | x | x | x | x | 
| Viral infection | Viral infection |  |  |  | x |  |  | x |  |  |  |  |  |  | 
| Deep vein thrombosis | Deep vein thrombosis |  |  |  |  |  |  |  |  | x |  |  |  |  | 
| Myocardial ischaemia | Myocardial ischaemia |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Uterine polyp | Uterine polyp |  |  | x |  |  |  |  |  |  |  |  |  |  | 
| Trigger finger | Trigger finger |  |  |  |  |  |  |  | x |  | x | x | x | x | 
| Malaise | Sickness |  |  | x | x |  |  |  | x | x | x | x | x | x | 
| Vulvovaginal dryness | Vaginal dryness |  |  |  |  |  |  | x |  |  |  |  |  |  | 
| Neuropathy peripheral | Neuropathy |  |  | x |  |  |  | x | x | x | x | x | x | x | 
| Osteoporotic fracture | Osteoporotic fracture |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Liver disorder | Hepatic impairment |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Coronary artery disease | Coronary artery disease |  |  |  |  | x | x |  | x | x | x | x | x | x | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 54 | 
|---|
		| Source: | medicines.org.au | 
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		| Side effects: | 54 | 
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		| Source: | Medsafe | 
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		| Side effects: | 48 | 
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		| Source: | FDA | 
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		| Side effects: | 48 | 
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		| Source: | FDA | 
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		| Side effects: | 53 | 
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		| Source: | BC Cancer | 
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		| Side effects: | 65 | 
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		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 80 | 
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		| Source: | Health Canada | 
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		| Side effects: | 74 | 
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		| Source: | FDA | 
|---|
		 
	  
	  
		| Side effects: | 78 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 81 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 84 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
  
 
  
	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |