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Goserelin

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L02AE03

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Amenorrhoea Amenorrhoea 100% x
Menopausal symptoms Hot flush 46% - 96% x x x x x x
Hot flush Hot flush 46% - 96% x x x x x x
Vaginal inflammation Vaginal inflammation 1% - 75% 6% x x
Vaginal infection Vaginal inflammation 1% - 75% 6% x x
Libido decreased Libido decreased 44% - 61% x x x x
Disturbance in sexual arousal Libido decreased 44% - 61% x x x x
Libido increased 12% - 19% x
Depression Depression 3% - 54% 7% x x x
Diarrhoea Diarrhoea 1.28% - 40% x x x x
Seborrhoeic dermatitis Seborrhoeic dermatitis 26% - 52% x x x
Breast atrophy Breast atrophy 33% - 42% x
Mood swings Mood swings postmarketing, 56% - 60% x x x x x x
Affect lability Mood swings postmarketing, 56% - 60% x x x x x x
Acne Acne postmarketing, 42% - 55% x x
Sexual dysfunction Sexual dysfunction 15% - 21% x x x
Rectal haemorrhage Rectal haemorrhage 20% x x
Breast enlargement Breast enlargement 15% - 18% x x x
Cystitis Cystitis 16% x x
Bladder pain Cystitis 16% x x
Cystitis noninfective Cystitis 16% x x
Libido increased Libido increased 12% - 19% x
Hyperhidrosis Sweating 4% - 45% 5% x x x
Hyperhidrosis x x
Pain Pain 3% - 31% x x x
Dyspareunia Dyspareunia 5% - 14% x x
Tumour flare Tumour flare 4% - 23% x x x
Oedema peripheral Oedema peripheral 2.56% - 34% x x x
Hirsutism Hirsutism 7% - 15% x x
Lower urinary tract symptoms Lower urinary tract symptoms 8% - 13% x x x
Nocturia Nocturia 10% x
Constipation Constipation 1-10% - 12% x x x x
Asthenia Asthenia 5% - 13% x x x
Fatigue 2% - 5% x x x
Gynaecomastia Gynaecomastia 1-5% - 8.3% x x x x x
Nausea Nausea 2% - 14% 6% x x x x
Proctitis Proctitis 8% x x
Hair disorder Hair disorder 4% - 11% x x
Pelvic pain Pelvic pain 5.7% - 22% 6% x x x x
Abdominal pain Abdominal pain 0% - 11% 10% x x x
Gastrointestinal pain Abdominal pain 0% - 11% 10% x x x
Dermatitis Rash 1% - 8% x x x x x x
Rash Rash 1% - 8% x x x x x x
Myalgia Myalgia 3% - 11% x x
Musculoskeletal discomfort Myalgia 3% - 11% x x
Arthralgia 1-10% x x x x x x
Haematuria Haematuria 1.28% - 12% x x x
Dysmenorrhoea Dysmenorrhoea 1-10% - 7% 9% x x
Migraine Migraine 1-10% - 7% 4% x x x
Infection Infection 0% - 13% x x x x
Uterine haemorrhage Uterine haemorrhage 6% 4% x
Application site reaction Application site reaction 6% x
Bone pain Bone pain 5.7% - 6% x x x x x
Back pain Back pain 0% - 16% 7% x x x
Alopecia Alopecia 1-10% x x x x x
Body hair loss x x
Anxiety Anxiety 1-10% x x x x
Arrhythmia Arrhythmia 1-10% x x x
Arthralgia Arthralgia 1-10% x x x x x x
Bronchitis Bronchitis 1-10% x x x
Cough Cough 1-10% x
Cough increased 0% - 2.55% x x x
Dyspepsia Dyspepsia 1-10% x x x x
Oedema Oedema 0% - 8% x x x x
Epistaxis Epistaxis 1-10% x x x
Flatulence Flatulence 1-10% x x x
Gout Gout 1-10% x x x
Haemorrhage Haemorrhage 1-10% x x x
Haemoglobin Haemorrhage 1-10% x x x
Hypersensitivity Hypersensitivity 1-10% x x x x
Hypertension Hypertension postmarketing, 1-10% - 12% 2% x x x x x x
Arthropathy Arthropathy 1-10% x x x
Osteoarthritis Arthropathy 1-10% x x x
Hypertonia Hypertonia 1% - 10% x x
Tachycardia Tachycardia 1-10% x x x
Ulcer Ulcer 1-10% x x x
Weight increased Weight increased 3% - 23% x x x x x
Dry mouth Dry mouth 1-10% x x x
Peripheral vascular disorder Peripheral vascular disorder 1-10% x x x
Chills Chills 1-10% x x x
Nervousness Nervousness 3% - 5% 3% x x x
Tension Nervousness 3% - 5% 3% x x x
Pharyngitis Pharyngitis 2% - 6% 9% x x
Vulvovaginitis Vulvovaginitis 5% 1% x
Insomnia Insomnia 1% - 16% x x x x
Upper respiratory tract infection Upper respiratory tract infection 2% - 7% x x x
Lethargy Lethargy 2% - 8% x x
Urinary tract infection Urinary tract infection 3.85% - 1-10% x x x x
Sinusitis Sinusitis 3% - 1-10% 6% x x x
Breast pain Breast pain 2.56% - 7% x x x x
Dizziness Dizziness 0% - 6% x x x x
Muscle spasms Cramps of lower extremities 2% - 6% x x
Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease 3% - 5% x x x
Bronchial hyperreactivity Chronic obstructive pulmonary disease 3% - 5% x x x
Menorrhagia Menorrhagia 4% 5% x x
Vomiting Vomiting postmarketing, 4% - 7% x x x x
Decreased appetite Anorexia 2% - 5% x x x x
Fatigue Fatigue 2% - 5% x x x
Malaise Malaise 2% - 5% x x x
Discomfort Malaise 2% - 5% x x x
Feeling abnormal Malaise 2% - 5% x x x
Confusional state x
Ill-defined disorder Malaise 2% - 5% x x x
Increased appetite Increased appetite 2% - 5% x x x
Influenza Influenza 0% - 5% x x x
Cardiac failure congestive Cardiac failure congestive 1% - 5% x
Paraesthesia Paraesthesia 1.27% - 1-10% x x x x x x
Erectile dysfunction Erectile dysfunction 1.27% - 90% x x x x x
Urethral disorder Urinary tract disorder 1.28% - 3.18% x x x x
Urinary tract disorder Urinary tract disorder 1.28% - 3.18% x x x x
Anaemia Anaemia 0% - 1-10% x x x x
Dyspnoea Dyspnoea 0% - 3.82% x x
Headache Headache postmarketing, 0% - 75% 22% x x x x x
Pruritus Pruritus 0% - 6% x x x
Adverse reaction Reaction aggravation 0% - 3.18% x x
Pollakiuria Pollakiuria 0% - 12% x x x x x
Sepsis Sepsis 0% - 2.55% x x
Angina pectoris Angina pectoris 0.637% - 1.28% x x
Bladder neoplasm Bladder neoplasm 0.637% - 1.28% x x
Herpes simplex Herpes simplex 0.637% - 1.28% x x
Cardiac failure Cardiac failure 0% - 1.91% x x x x
Dysuria Urination impaired 0% - 1.91% x x
Haematemesis Haematemesis 0% - 1.28% x x
Varicose vein Varicose vein 0% - 1.28% x x
Diabetes mellitus Diabetes mellitus 0% - 1.27% x x x x x
Pneumonia Pneumonia 0% - 1.27% x x
Urinary incontinence Urinary incontinence 0% - 1.27% x x
Urinary retention Urinary retention 0% - 1.27% x x x
Cerebral ischaemia Cerebral ischaemia 0% - 1.27% x x
Transient ischaemic attack Transient ischaemic attack postmarketing x
Multiple fractures Fracture postmarketing x x x
Fracture Fracture postmarketing x x x
Hypercalcaemia Hypercalcaemia postmarketing x x x
Hypotension Hypotension postmarketing x x x x x x
Myocardial infarction Myocardial infarction postmarketing x x x x x x
Acute coronary syndrome Myocardial infarction postmarketing x x x x x x
Neoplasm Neoplasm postmarketing x x x x
IIIrd nerve paralysis Ophthalmoplegia postmarketing x x
Ophthalmoplegia Ophthalmoplegia postmarketing x x
Osteoporosis Osteoporosis postmarketing x x x
Ovarian cyst Ovarian cyst postmarketing x x x x
Pituitary tumour benign Pituitary adenoma postmarketing, 1% x x x
Pituitary haemorrhage Pituitary apoplexy postmarketing x x x
Pituitary haemorrhage x x
Pituitary tumour Pituitary tumour postmarketing x x x x
Psychotic disorder Psychotic disorder postmarketing x x x x
Pulmonary embolism Pulmonary embolism postmarketing, 0% - 1.27% x x x
Convulsion Convulsion postmarketing x x
Shock Shock postmarketing x x
Cerebrovascular accident Cerebrovascular accident postmarketing, 0% - 1.27% x x x
Ovarian hyperstimulation syndrome Ovarian hyperstimulation syndrome postmarketing x x
Deep vein thrombosis Deep vein thrombosis postmarketing x x
Bone cancer metastatic Bone cancer metastatic postmarketing x
Mental disorder Mental state abnormal postmarketing x x
Mental disorder x x
Pituitary infarction Pituitary infarction postmarketing x x
Blood pressure fluctuation Change in blood pressure postmarketing x x x x
Amblyopia Amblyopia x x
Anaphylactic shock Anaphylactic shock x x x x
Blood pressure abnormal Blood pressure abnormal x x
Bone disorder Bone disorder x x
Breast disorder Breast disorder x x
Breast swelling Breast swelling x x
Chest pain Chest pain x x
Confusional state Confusional state x
Cyst Cyst x x
Somnolence Drowsiness x
Somnolence x x
Drug hypersensitivity Drug hypersensitivity x x
Ecchymosis Ecchymosis x x x
Endocrine disorder Endocrine disorder x x
Extravasation Extravasation x
Eye disorder Eye disorder x
Body temperature increased Body temperature increased x x x
Cardiac disorder Cardiac disorder x x
Hepatitis Hepatitis x
Herpes zoster Herpes zoster x
Hypercholesterolaemia Hypercholesterolaemia x
Hyperglycaemia Hyperglycaemia x x
Hyperlipidaemia Hyperlipidaemia x
Immune system disorder Immune system disorder x x
Incontinence Incontinence x x
Infarction Infarction x x
Jaundice Jaundice x
Leukopenia Leukopenia x x
Lymphoedema Lymphoedema x x
Nervous system disorder Nervous system disorder x x
Nodule Nodule x
Palpitations Palpitations x x
Polyp Polyp x x
Rhinitis Rhinitis x x
Spinal cord compression Spinal cord compression x x x x x
Swelling Swelling x
Thirst Thirst x
Thrombocytopenia Thrombocytopenia x x
Thrombophlebitis Thrombophlebitis x
Erythema Erythema x
Ureteric obstruction Ureteric obstruction x x x x x
Urticaria Urticaria x
Angiopathy Angiopathy x x
Vasodilation procedure Vasodilation x
Sudden cardiac death Sudden cardiac death x
Hepatic function abnormal Hepatic function abnormal x
High density lipoprotein decreased High density lipoprotein decreased x
Low density lipoprotein increased x x
Injection site reaction Injection site reaction x x x x x
Skin discolouration Skin discolouration x x
Dry skin Dry skin x x x
Uterine leiomyoma Degeneration of uterine fibroid x
Malnutrition Malnutrition x x
Photosensitivity reaction Photosensitivity reaction x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x
Thinking abnormal Thinking abnormal x x
Mental disability Thinking abnormal x x
Tenderness Tenderness x x x
Galactorrhoea Galactorrhoea x
Condition aggravated Condition aggravated x x
Muscle mass Muscle mass x
Blood testosterone decreased Testosterone low x x
Vulvovaginal dryness Vaginal dryness x x x
Vulvovaginal dryness x
Breast tenderness Breast tenderness x x x x
Glucose tolerance impaired Glucose tolerance impaired x x
Dry eye Dry eye x x
Vision blurred Vision blurred x
Injection site irritation Injection site irritation x
Low density lipoprotein increased Low density lipoprotein increased x x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Febrile neutropenia Febrile neutropenia x
Amnesia Memory loss x
Sleep disorder Sleep disorder x
Tumour pain Tumour pain x
Bone density decreased Bone density decreased x x
Lupus-like syndrome Lupus-like syndrome x
Blood cholesterol increased High cholesterol x
Renal failure Renal impairment x x
Renal impairment Renal impairment x x
Vaginal haemorrhage Vaginal haemorrhage x x
Loss of libido Loss of libido x
Metrorrhagia Bleeding breakthrough x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

goserelin / ZOLADEX IMPLANT

Side effects:47
Source:medicines.org.au

goserelin / ZOLADEX IMPLANT

Side effects:57
Source:medicines.org.au

goserelin

Side effects:93
Source:BC Cancer

GOSERELIN

Side effects:128
Source:FDA Structured Product Label

GOSERELIN

Side effects:130
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label