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Ovarian hyperstimulation syndrome

Definition: A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.

Synonyms (terms occurring on more labels are shown first): OHSS, ovarian hyperstimulation syndrome, Ovarian Hyper-Stimulation Syndrome

More information: PubMed search and possibly Wikipedia

Show drugs for which this side effect directly occurs

Drugs with this side effect as MedDRA Preferred Term

  • Goserelin
    • Ovarian hyperstimulation syndrome: postmarketing
  • Metrodin
    • Ovarian hyperstimulation syndrome: very rare, postmarketing, rare, uncommon, common, 3.65% - 11.4%
    • Ovarian hyperstimulation: 3.5% - 7.23%
  • Nafarelin
    • Ovarian hyperstimulation syndrome
    • Ovarian hyperstimulation
  • Org 37462
    • Ovarian hyperstimulation syndrome
  • cetrorelix
    • Ovarian hyperstimulation syndrome
  • clomiphene citrate
    • Ovarian hyperstimulation syndrome
  • gonadorelin
    • Ovarian hyperstimulation syndrome: very rare, common
    • Ovarian hyperstimulation: 2.33% - 5.93%
  • progesterone
    • Ovarian hyperstimulation syndrome: 6.68% - 7.43%