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Progesterone

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: G03DA04

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Pain Pain 7% - 28.5% x x x x x x x
Abdominal pain Abdominal pain 10% - 20% 10% - 13% x x x x x x x x x x x x x
Gastrointestinal pain Abdominal pain 10% - 20% 10% - 13% x x x x x x x x x x x x x
Depression Depression 18% 12% x x x x x x x x x x x
Muscle spasms Cramp muscle postmarketing, 13% - 20% 13% x x x x x x x x x x x
Cramps of lower extremities x x x x
Headache Headache postmarketing, 3.22% - 30% 8% - 27% x x x x x x x x x x x x x x x x
Breast pain Breast pain 6% - 16% 2% - 8% x x x x x x x x x x
Breast tenderness Breast tenderness postmarketing, 14% - 16% 6% x x x x x x x x x x x x x x
Menopausal symptoms Hot flush 14% 35% x x x x x x x x x
Hot flush Hot flush 14% 35% x x x x x x x x x
Musculoskeletal pain Musculoskeletal pain 4% - 12% 4% x x x x x x x
Viral infection Viral infection 0% - 12% 0% x x x x x x
Vaginal discharge Vaginal discharge 7% - 10% 3% x x x x x x x x x x x x
Leukorrhea x x x
Local swelling Hand swelling 9% 9% x x x x x x x
Abdominal distension Abdominal distension 4.21% - 8% 8% x x x x x x x x x x
Abdominal bloating 7% - 10% 5% - 8% x x x x x x x x x x x x x
Back pain Back pain 8% 8% x x x x x x x x x
Cough Cough 0% - 8% 0% x x x x x x
Diarrhoea Diarrhoea 4% - 8% 4% x x x x x x x x x x
Asthenia Fatigue 1.73% - 9% 4% x x x x x x x x x x x x x x
Asthenia x x x x
Fatigue Fatigue 1.73% - 9% 4% x x x x x x x x x x x x x x
Irritability Irritability 4% - 8% 4% x x x x x x x x x
Nausea Nausea postmarketing, 0% - 8% 0% - 7% x x x x x x x x x x x x x x x x
Vulvovaginal dryness Vaginal dryness 8% 10% x x x x x x x x
Vulvovaginal dryness x
Flatulence Abdominal bloating 7% - 10% 5% - 8% x x x x x x x x x x x x x
Flatulence x
Ovarian hyperstimulation syndrome Ovarian hyperstimulation syndrome 6.68% - 7.43% x x
Vomiting Vomiting 2.23% - 6% 7% x x x x x x x x x x x x
Mood swings Mood swings 6% x x x x x x x
Affect lability Mood swings 6% x x x x x x x
Dizziness Dizziness postmarketing, 4% - 24% 4% - 9% x x x x x x x x x x x x x x
Syncope postmarketing x x x x x x x x
Lightheadedness x
Night sweats Night sweats 5% 17% x x x x x x x
Upper respiratory tract infection Upper respiratory tract infection 5% x x x x x x x x x
Anxiety Worry 5% 4% x x x x x x x
Anxiety x x x
Chest pain Chest pain 4% 5% x x x x x x x
Vaginal haemorrhage Vaginal haemorrhage 3.22% - 3.47% x x x
Uterine spasm Uterine spasm 2.72% - 3.71% x x x
Constipation Constipation 2.23% - 3.47% 2% x x x x x x x x x x x x
Urinary tract infection Urinary tract infection 0.99% - 2.23% x x x x x x x x x x
Breast cancer Carcinoma breast 1% 1% x x x x x x
Abortion spontaneous Abortion spontaneous postmarketing x x x x x
Pancreatitis acute Pancreatitis acute postmarketing x x x x x
Aggression Aggression postmarketing x x x x x
Alopecia Alopecia postmarketing x x x x x x x
Anaphylactic shock Anaphylactic shock postmarketing x x x x x x x x x
Anaphylactoid reaction x x x x x
Arthralgia Arthralgia postmarketing, 22% 29% x x x x x x x x x x x
Musculoskeletal discomfort Arthralgia postmarketing, 22% 29% x x x x x x x x x x x
Myalgia x x x x x
Asthma Asthma postmarketing x x x x x x
Exacerbation of asthma x
Mental disorder Mental disorder postmarketing x x x x x
Breast disorder Breast disorder postmarketing x x x x x
Transient ischaemic attack Transient ischaemic attack postmarketing x x x x x
Choking Choking postmarketing x x x x x
Cholestasis Cholestasis postmarketing x x x x x x
Cleft lip Cleft lip postmarketing x x x x x
Cleft palate Cleft palate postmarketing x x x x x
Confusional state Confusional state postmarketing x x x x x x x x
Feeling abnormal Confusional state postmarketing x x x x x x x x
Malaise postmarketing x
Feeling abnormal postmarketing x x x x x
Dysphagia Dysphagia postmarketing x x x x x
Depersonalisation Depersonalisation postmarketing x x x x x
Diplopia Diplopia postmarketing x x x x x
Somnolence Drowsiness postmarketing x x x x x x x
Somnolence postmarketing x x x x x x x x x
Patent ductus arteriosus Patent ductus arteriosus postmarketing x x x x x
Dysarthria Dysarthria postmarketing x x x x x
Slurred speech postmarketing x x x x
Osteoarthritis Dysarthria postmarketing x x x x x
Dyspnoea Dyspnoea postmarketing x x x x x x
Foetal death Foetal death postmarketing x x x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing x x x x x x
Digestion impaired x
Ventricular septal defect Ventricular septal defect postmarketing x x x x x
Hepatitis Hepatitis postmarketing x x x x x x x
Hypersensitivity Hypersensitivity postmarketing x x x x x x x
Hypertension Hypertension postmarketing x x x x x x x
Hypotension Hypotension postmarketing x x x x x x
Jaundice Jaundice postmarketing x x x x x x x
Menorrhagia Menorrhagia postmarketing x x x x x
Menstrual disorder Menstrual disorder postmarketing x x x x x
Metrorrhagia Metrorrhagia postmarketing x x x x x x x x x x x x
Bleeding breakthrough postmarketing x x x x x x x
Ovarian cyst Ovarian cyst postmarketing x x x x x
Paraesthesia Paraesthesia postmarketing x x x x x
Pruritus Pruritus postmarketing x x x x x x x x x x x x
Convulsion Convulsion postmarketing x x x x x
Shock Shock postmarketing x x x x x
Syncope postmarketing x x x x x x x x
Syncope Syncope postmarketing x x x x x x x x
Loss of consciousness Syncope postmarketing x x x x x x x x
Loss of consciousness postmarketing x x x x x
Tachycardia Tachycardia postmarketing x x x x x
Tinnitus Tinnitus postmarketing x x x x x
Urticaria Urticaria postmarketing x x x x x x x x x x x
Vertigo Vertigo postmarketing x x x x x x
Weight increased Weight increased postmarketing x x x x x
Weight decreased Weight decreased postmarketing x x x x x
Hepatic failure Hepatic failure postmarketing x x x x x
Stupor Stupor postmarketing x x x x x
Depressed level of consciousness Stupor postmarketing x x x x x
Hepatitis cholestatic Hepatitis cholestatic postmarketing x x x x x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased postmarketing x x x x x
Hepatic necrosis Hepatic necrosis postmarketing x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased postmarketing x x x x x
Alanine aminotransferase increased Alanine aminotransferase increased postmarketing x x x x x
Heart disease congenital Heart disease congenital postmarketing x x x x x
Malaise Malaise postmarketing x
Discomfort Malaise postmarketing x
Discomfort x x
Ill-defined disorder Malaise postmarketing x
Disorientation Disorientation postmarketing x x x x x
Swollen tongue Swollen tongue postmarketing x x x x x
Throat tightness Throat tightness postmarketing x x x x x
Walking disability Walking disability postmarketing x x x x x
Gait disturbance Walking disability postmarketing x x x x x
Gait disturbance postmarketing x x x x x
Vision blurred Vision blurred postmarketing x x x x x
Suicidal ideation Suicidal ideation postmarketing x x x x x
Endometrial cancer Endometrial cancer postmarketing x x x x x
Feeling drunk Feeling drunk postmarketing x x x x x
Face oedema Face oedema postmarketing x x x x x x
Visual impairment Visual disturbance postmarketing x x x x x x x
Disorder sight x x x
Abnormal vision x x x
Blood glucose increased Blood glucose increased postmarketing x x x x x
Stillbirth Stillbirth postmarketing x x x x x
Liver function test abnormal Raised liver function tests postmarketing x x x x x
Abscess Abscess x x x
Amenorrhoea Amenorrhoea x x x
Anaemia Anaemia x
Angina pectoris Angina pectoris x x x
Angioedema Angioedema x
Decreased appetite Anorexia x x x
Decreased appetite x
Arthritis Arthritis x x x
Coagulopathy Clotting x
Breast swelling Breast swelling x x
Bronchitis Bronchitis x x x
Neoplasm malignant Neoplasm malignant x
Uterine cervical erosion Uterine cervical erosion x x
Chorea Chorea x
Infection Infection x x x x
Conjunctivitis Conjunctivitis x
Connective tissue disorder Connective tissue disorder x x
Coronary artery thrombosis Coronary artery thrombosis x
Cystitis Cystitis x x x
Bladder pain Cystitis x x x
Cystitis noninfective Cystitis x x x
Libido decreased Libido decreased x x
Disturbance in sexual arousal Libido decreased x x
Dysmenorrhoea Dysmenorrhoea x x x x x x x
Dyspepsia Dyspepsia x x x x
Digestion impaired x
Dysuria Dysuria x x
Ear pain Ear pain x x x
Oedema Oedema x x x x x x
Embolism Embolism x
Thromboembolism x x
Endocrine disorder Endocrine disorder x
Endometrial hyperplasia Endometrial hyperplasia x x
Endometriosis Endometriosis x
Eructation Eructation x
Erythema multiforme Erythema multiforme x x x
Erythema nodosum Erythema nodosum x x x
Dermatitis Rash x x x x x x x x
Rash Rash x x x x x x x x
Eye disorder Eye disorder x x
Assisted fertilisation Fertilization x x
Body temperature increased Body temperature increased x x x x x x
Gallbladder disorder Gallbladder disorder x x
Gastritis Gastritis x
Gastroenteritis Gastroenteritis x x x
Cardiac disorder Cardiac disorder x x
Haemangioma Haemangioma x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Herpes simplex Herpes simplex x x x
Hirsutism Hirsutism x x x x
Hyperglycaemia Hyperglycaemia x
Hypernatraemia Hypernatraemia x
Hyperventilation Hyperventilation x
Hypocalcaemia Hypocalcaemia x
Immune system disorder Immune system disorder x
Infertility Infertility x
Jaundice cholestatic Jaundice cholestatic x x x x x
Premature labour Premature labour x
Pain in extremity Leg pain x x
Liver disorder Liver disorder x
Hepatocellular injury Liver disorder x
Foetor hepaticus Liver disorder x
Mediastinal disorder Mediastinal disorder x
Chloasma Chloasma x x x x x
Hypertonia Hypertonia x x x
Myopathy Myopathy x x x
Musculoskeletal disorder Musculoskeletal disorder x
Nasal congestion Nasal congestion x x x
Nasopharyngitis Nasopharyngitis x x x x
Neoplasm Neoplasm x x
Nervous system disorder Nervous system disorder x x x x x
Nervousness Nervousness x x x x x x x
Tension Nervousness x x x x x x x
Neuritis Neuritis x
Neuropathy peripheral Neuritis x
Neuropathy peripheral x x
Nocturia Nocturia x x
Optic neuritis Optic neuritis x x
Palpitations Palpitations x x x x
Personality disorder Personality disorder x x x
Pharyngitis Pharyngitis x x x x
Pneumonia Pneumonia x x x
Porphyrin metabolism disorder Porphyrin metabolism disorder x
Pregnancy Pregnancy x
Premenstrual syndrome Premenstrual syndrome x
Premenstrual tension x
Pruritus genital Pruritus genital x x x
Pulmonary embolism Pulmonary embolism x x
Purpura Purpura x
Dermatitis hemorrhagic x x x
Vascular purpura Purpura x
Rhinitis Rhinitis x
Seborrhoeic dermatitis Seborrhoeic dermatitis x
Sinusitis Sinusitis x x x x
Skin disorder Skin disorder x
Unspecified disorder of skin and subcutaneous tissue x x x
Speech disorder Speech disorder x x x x
Swelling Swelling x
Thirst Thirst x
Embolism venous Thromboembolism x x
Thrombophlebitis Thrombophlebitis x
Thrombosis Thrombosis x x
Tooth disorder Tooth disorder x x x
Toothache Toothache x
Tremor Tremor x
Pollakiuria Pollakiuria x
Urethral disorder Urinary tract disorder x x x x
Urinary tract disorder Urinary tract disorder x x x x
Uterine leiomyoma Uterine leiomyoma x x x
Vulvovaginal pruritus Vaginal itching x
Vaginal inflammation Vaginal inflammation x x x
Vaginal infection Vaginal inflammation x x x
Angiopathy Angiopathy x x
Skin papilloma Common wart x x x
Xerophthalmia Xerophthalmia x
Dry mouth Dry mouth x x x x
Cerebral thrombosis Cerebral thrombosis x
Oedema peripheral Oedema peripheral x x x x x x
Hepatic function abnormal Hepatic function abnormal x
Breast discharge Breast discharge x
Migraine Migraine x x x
Glucose tolerance decreased Glucose tolerance decreased x
Injury Accidental injury x x x
Bone pain Bone pain x
Skin discolouration Skin discolouration x
Withdrawal bleed Withdrawal bleed x
Menstruation irregular Menstruation irregular x
Malnutrition Malnutrition x x
Myalgia Myalgia x x x x x
Increased appetite Increased appetite x x x x x
Abdominal discomfort Abdominal discomfort x
Tenderness Tenderness x
Disturbance in attention Cerebration impaired x x x x
Mental disability Cerebration impaired x x x x
Perineal pain Perineal pain female x x
Galactorrhoea Galactorrhoea x x
Crying Crying abnormal x
Hepatic enzyme increased Hepatic enzyme increased x
Vulvovaginal burning sensation Vaginal burning sensation x
Hepatobiliary disease Hepatobiliary disease x x
Fluid retention Fluid retention x x
Water retention x
Erythema Redness x
Anaphylactoid reaction Anaphylactoid reaction x x x x x
Genital candidiasis Genital candidiasis x x
Influenza like illness Influenza-like symptoms x
Transaminases increased Transaminases increased x x
Lymphadenopathy Lymphadenopathy x x x
Blood pressure increased Blood pressure increased x x
Rash generalised Rash generalised x
Vulvovaginal discomfort Vulvovaginal discomfort x
Vaginal irritation x x x
Memory impairment Forgetfulness x
Pelvic venous thrombosis Pelvic venous thrombosis x
Vulvovaginal mycotic infection Vaginal mycosis x x x x x
Drug interaction Drug interaction x
Hyperhidrosis Sweating increased x x x x
Acne Acne x
Ovarian failure Ovarian failure x x x
Infestation Infestation NOS x x
Sleep disorder Sleep disorder x x
Breast discomfort Breast discomfort x
Insomnia Insomnia x x x x x x x
Ovarian cancer Ovarian cancer x
Autonomic neuropathy Unspecified disorder of autonomic nervous system x x
Dyspareunia Dyspareunia x x x
Breast enlargement Breast enlargement x x x x x
Hiatus hernia Hiatus hernia x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

PROGESTERONE / CRINONE

Side effects:11
Source:Health Canada

Progesterone / Utrogestan, Capsule

Side effects:20
Source:Medsafe

PROGESTERONE / ENDOMETRIN

Side effects:26
Source:FDA

Progesterone

Side effects:28
Source:FDA Structured Product Label

ENDOMETRIN PESSARIES progesterone100 mg vaginal tablets

Side effects:29
Source:medicines.org.au

Progesterone / Utrogestan, Capsule

Side effects:19
Source:Medsafe

PROGESTERONE

Side effects:37
Source:FDA Structured Product Label

PROGESTERONE

Side effects:32
Source:FDA Structured Product Label

PROGESTERONE / CRINONE

Side effects:86
Source:FDA

PROGESTERONE / PROMETRIUM - CAP 100MG

Side effects:94
Source:Health Canada

PROGESTERONE / PROMETRIUM

Side effects:92
Source:FDA

progesterone / Prometrium

Side effects:94
Source:FDA

Progesterone

Side effects:79
Source:FDA Structured Product Label

PROGESTERONE

Side effects:99
Source:FDA Structured Product Label

PROGESTERONE

Side effects:99
Source:FDA Structured Product Label

PROGESTERONE

Side effects:99
Source:FDA Structured Product Label

PROGESTERONE

Side effects:179
Source:FDA Structured Product Label

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label