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Acitretin

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: D05BB02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Hypertriglyceridaemia Hypertriglyceridaemia 65% x x
Blood triglycerides increased Hypertriglyceridaemia 65% x x
Blood uric acid increased Uric acid level increased 17% x
Dry eye Dry eye 30% x
Hypercholesterolaemia Hypercholesterolaemia 9% x
White blood cell count decreased White blood cell count decreased 7% x x
Erectile dysfunction Erectile dysfunction 1-10% x x
Blood creatinine increased Creatinine increased 5% x x
Glycosuria Glycosuria postmarketing, 4% x x x x
Ketonuria Ketonuria postmarketing, 3% x x x x
Proteinuria Proteinuria postmarketing, 2% x x x x
Protein urine present Proteinuria postmarketing, 2% x x x x
Abdominal pain Abdominal pain postmarketing x x x x
Gastrointestinal pain Abdominal pain postmarketing x x x x
Alopecia Alopecia postmarketing, 7-75% x x x x x x
Angioedema Angioedema postmarketing x x x x
Decreased appetite Anorexia postmarketing, 1-10% x x x x x
Anorectal disorder Anus disorder postmarketing x x x x
Anxiety Anxiety postmarketing x x x
Arthralgia Arthralgia postmarketing x x x x x
Musculoskeletal discomfort Arthralgia postmarketing x x x x x
Myalgia postmarketing x x x x x
Arthritis Arthritis postmarketing, 1-10% x x x x x
Back pain Back pain postmarketing, 1-10% x x x x x
Blepharitis Blepharitis postmarketing x x x x x
Bone disorder Bone disorder postmarketing x x x
Candida infection Candida infection postmarketing x x x x
Chalazion Chalazion postmarketing x x x
Cheilitis Cheilitis postmarketing x x x x x x
Chest pain Chest pain postmarketing x x x x
Infection Infection postmarketing x x x x x
Conjunctival haemorrhage Conjunctival haemorrhage postmarketing x x x
Conjunctivitis Conjunctivitis postmarketing x x x x x
Constipation Constipation postmarketing x x x x
Ulcerative keratitis Ulcerative keratitis postmarketing x x x x
Cough Cough postmarketing x x x x
Cyanosis Cyanosis postmarketing x x x
Cyst Cyst postmarketing x x x
Deafness Deafness postmarketing x x x x
Libido decreased Libido decreased postmarketing x x x
Disturbance in sexual arousal Libido decreased postmarketing x x x
Depression Depression postmarketing x x x x
Dermatitis Dermatitis postmarketing x x x x x
Rash postmarketing x x x x x
Dermatitis exfoliative Dermatitis exfoliative postmarketing x x x
Scleroderma Scleroderma postmarketing x x x
Diarrhoea Diarrhoea postmarketing x x x x
Diplopia Diplopia postmarketing x x x
Dizziness Dizziness postmarketing x x x
Dysgeusia Dysgeusia postmarketing, 1-10% x x x x x
Dyspepsia Dyspepsia postmarketing x x x x
Dysuria Dysuria postmarketing x x x x
Ear pain Ear pain postmarketing, 1-10% x x x x x
Ectropion Ectropion postmarketing x x x
Eczema Eczema postmarketing x x x x
Oedema Oedema postmarketing, 1-10% x x x x x
Epistaxis Epistaxis postmarketing x x x x x x
Oesophagitis Oesophagitis postmarketing x x x
Rash Rash postmarketing x x x x x
Congenital eye disorder Congenital eye disorder postmarketing x x x x
Eye disorder Congenital eye disorder postmarketing x x x x
Eye disorder postmarketing x x x x
Fasting Fasting postmarketing x x x
Asthenia Fatigue postmarketing, 1-10% x x x x x
Fatigue Fatigue postmarketing, 1-10% x x x x x
Body temperature increased Body temperature increased postmarketing x x x x
Flushing Flushing postmarketing x x x x x
Furuncle Furunculosis postmarketing x x x
Gastritis Gastritis postmarketing x x x
Gastroenteritis Gastroenteritis postmarketing x x x
Gingival bleeding Gingival bleeding postmarketing x x x x
Gingival hyperplasia Gingival hyperplasia postmarketing x x x
Gingivitis Gingivitis postmarketing x x x x x
Glossitis Glossitis postmarketing x x x x
Headache Headache postmarketing x x
Haematuria Haematuria postmarketing x x x
Haemorrhage Haemorrhage postmarketing x x x x
Haemoglobin Haemorrhage postmarketing x x x x
Haemorrhoids Haemorrhoids postmarketing x x x
Hepatitis Hepatitis postmarketing x x x x
Herpes simplex Herpes simplex postmarketing x x x
Hyperaesthesia Hyperaesthesia postmarketing x x x x x
Exostosis Hyperostosis postmarketing, 1-10% x x x x
Senile ankylosing vertebral hyperostosis Senile ankylosing vertebral hyperostosis postmarketing x x x x x
Hypersensitivity Hypersensitivity postmarketing x x x
Hypertrichosis Hypertrichosis postmarketing x x x
Hypoaesthesia Hypoaesthesia postmarketing x x x x
Immune system disorder Immune system disorder postmarketing x x x
Intermittent claudication Intermittent claudication postmarketing x x x
Eye pruritus Eye pruritus postmarketing x x x
Jaundice Jaundice postmarketing x x x x x
Arthropathy Arthropathy postmarketing x x x x
Osteoarthritis Arthropathy postmarketing x x x x
Laryngitis Laryngitis postmarketing x x x x
Vaginal discharge Leukorrhea postmarketing x x x x
Breast pain Breast pain postmarketing x x x
Melaena Melaena postmarketing x x x x
Hypertonia Hypertonia postmarketing, 1-10% x x x x x
Myopathy Myopathy postmarketing x x x
Fungal infection Fungal infection postmarketing x x x
Nail disorder Nail disorder postmarketing x x x x
Nausea Nausea postmarketing, 1-10% x x x x x x
Nervousness Nervousness postmarketing, 1-10% x x x x x
Tension Nervousness postmarketing, 1-10% x x x x x
Neuritis Neuritis postmarketing x x x
Neuropathy peripheral Neuritis postmarketing x x x
Neuropathy peripheral postmarketing x x x x
Night blindness Night blindness postmarketing x x x
Decreased night vision postmarketing, 1% x x x x x
Otitis externa Otitis externa postmarketing x x x x
Otitis media Otitis media postmarketing x x x
Pain Pain postmarketing x x x x x
Optic neuritis Papilloedema postmarketing x x x
Papilloedema Papilloedema postmarketing x x x
Paraesthesia Paraesthesia postmarketing x x x x
Paronychia Paronychia postmarketing x x x x x
Penis disorder Penis disorder postmarketing x x x
Pharyngitis Pharyngitis postmarketing x x x x
Pruritus Pruritus postmarketing, 10-50% x x x x x x
Benign intracranial hypertension Benign intracranial hypertension postmarketing, 1% x x x x x x
Psoriasis Psoriasis postmarketing x x
Psoriasis flare-up postmarketing x x x
Purpura Purpura postmarketing x x x x
Vascular purpura Purpura postmarketing x x x x
Rhinitis Rhinitis postmarketing x x x x x x
Seborrhoeic dermatitis Seborrhoeic dermatitis postmarketing x x x x
Salivary hypersecretion Salivary hypersecretion postmarketing x x x x
Sinusitis Sinusitis postmarketing x x x x
Skin disorder Skin disorder postmarketing x x x x
Skin mass Skin nodule postmarketing x x x x
Skin ulcer Skin ulcer postmarketing x x x x
Stomatitis Stomatitis postmarketing x x x x x
Mouth ulceration Ulcerative stomatitis postmarketing x x x x
Cerebrovascular accident Cerebrovascular accident postmarketing x x x
Sunburn Sunburn postmarketing x x x
Photosensitivity reaction Sunburn postmarketing x x x
Photosensitivity reaction postmarketing x x x x x
Photosensitivity x
Sweat gland disorder Sweat gland disorder postmarketing x x x
Tendonitis Tendonitis postmarketing x x x
Thirst Thirst postmarketing x x x x x
Embolism Thromboembolism postmarketing x x x
Embolism venous Thromboembolism postmarketing x x x
Tinnitus Tinnitus postmarketing, 1-10% x x x x x
Tongue disorder Tongue disorder postmarketing x x x
Urticaria Urticaria postmarketing x x x
Angiopathy Angiopathy postmarketing x x x
Vulvovaginitis Vulvovaginitis postmarketing x x x x x
Skin papilloma Common wart postmarketing x x x
Weight increased Weight increased postmarketing x x x
Xerophthalmia Xerophthalmia postmarketing x x x x x
Dry mouth Dry mouth postmarketing x x x x x x
Self injurious behaviour Self injurious behaviour postmarketing x x x
Intentional self-injury Self injurious behaviour postmarketing x x x
Photophobia Photophobia postmarketing x x x x x
Pyogenic granuloma Pyogenic granuloma postmarketing x x x x
Hepatic function abnormal Hepatic function abnormal postmarketing x x x
Migraine Migraine postmarketing x x x
Alcohol intolerance Alcohol intolerance postmarketing x x x x
Skin atrophy Skin atrophy postmarketing x x x x x
Skin thinness postmarketing x x x x
Bleeding time prolonged Bleeding time prolonged postmarketing x x x x
Hair colour changes Hair discoloration postmarketing x x x
Impaired healing Impaired healing postmarketing x x x x
Skin hypertrophy Skin hypertrophy postmarketing x x x x
Intracranial pressure increased Intracranial pressure increased postmarketing x x x x
Muscular weakness Muscular weakness postmarketing x x x x
Eye pain Eye pain postmarketing x x x x
Dry skin Dry skin postmarketing x x x x x
Skin irritation Skin irritation postmarketing x x x
Acute myocardial infarction Acute myocardial infarction postmarketing x x x
Skin fissures Skin fissures postmarketing x x x x x
Atrophic vulvovaginitis Vaginitis atrophic postmarketing x x x
Malaise Malaise postmarketing x x x x
Discomfort Malaise postmarketing x x x x
Feeling abnormal Malaise postmarketing x x x x
Ill-defined disorder Malaise postmarketing x x x x
Myalgia Myalgia postmarketing x x x x x
Increased appetite Increased appetite postmarketing, 1-10% x x x x x
Proctalgia Rectal tenesmus postmarketing x x x x
Rectal tenesmus Rectal tenesmus postmarketing x x x x
Anorectal discomfort Rectal tenesmus postmarketing x x x x
Rash erythematous Rash erythematous postmarketing x x x x
Skin odour abnormal Skin odour abnormal postmarketing x x x x
Tongue ulceration Tongue ulceration postmarketing x x x x
Peripheral ischaemia Peripheral ischaemia postmarketing x x x
Urine abnormality Urine abnormality postmarketing x x x x
Urine analysis abnormal Urine abnormality postmarketing x x x x
Saliva altered Saliva altered postmarketing x x x x
Hair texture abnormal Hair texture abnormal postmarketing x x x x x
Dermatitis bullous Bullous eruption postmarketing x x x x x
Lacrimal disorder Lacrimation abnormal NOS postmarketing x x x x x
Skin exfoliation Skin exfoliation postmarketing x x x x
Dermatitis psoriasiform Dermatitis psoriasiform postmarketing x x x
Bursitis Olecranon bursitis postmarketing x x x x
Madarosis Madarosis postmarketing x x x
Eyebrow loss of x
Cerumen impaction Ceruminosis postmarketing x x x x
Adenocarcinoma pancreas Adenocarcinoma pancreas postmarketing x x x
Capillary leak syndrome Capillary leak syndrome postmarketing x x x
Vision blurred Vision blurred postmarketing, 1- 10% x x x x x x
Cold sweat Sticky skin postmarketing x x x x x x
Sticky skin Sticky skin postmarketing x x x x x x
Influenza like illness Influenza-like symptoms postmarketing x x x
Suicidal ideation Suicidal ideation postmarketing x x x
Chills Rigors postmarketing x x x x x
Laboratory test abnormal Laboratory test abnormal postmarketing x x
Skin fragility Skin fragility postmarketing x x x
Monocyte count decreased Monocyte count decreased postmarketing x
Gait disturbance Gait disturbance postmarketing x x x x
Blood sodium increased Sodium high postmarketing x
Menopausal symptoms Hot flush postmarketing x x x x
Hot flush Hot flush postmarketing x x x x
Lung neoplasm malignant Carcinoma of lung postmarketing x x x
Hyperhidrosis Sweating increased postmarketing x x x x
Acne Acne postmarketing x x x x
White blood cell count increased White blood cell count increased postmarketing x x x
Hyperkeratosis Hyperkeratosis postmarketing x x x
Insomnia Insomnia postmarketing, 1-10% x x x x x
Dysphonia Dysphonia postmarketing x x x x
Ageusia Ageusia postmarketing x x x x
Somnolence Somnolence postmarketing x x x x
Congenital anomaly Congenital anomaly x
Developmental delay Congenital anomaly x
Alcoholism Alcoholism x
Alcohol abuse Alcoholism x
Balanoposthitis Balanoposthitis x
Pancytopenia Cytopenia x
Diabetes mellitus Diabetes mellitus x
Diabetic x
Gastrointestinal disorder Gastrointestinal disorder x
Hordeolum Hordeolum x x
Hyperlipidaemia Hyperlipidaemia x
Hypervitaminosis A Hypervitaminosis A x x x x x x
Iritis Iritis x
Muscle spasms Cramps of lower extremities x
Obesity Obesity x
Pancreatitis Pancreatitis x x
Retinal haemorrhage Retinal haemorrhage x
Scotoma Scotoma x
Erythema Erythema x x x
Redness x
Urinary tract infection Urinary tract infection x
Vasculitis Vasculitis x
Vomiting Vomiting x
Weight decreased Weight decreased x
Oedema peripheral Oedema peripheral x
Cataract Cataract x
High density lipoprotein decreased High density lipoprotein decreased x
Bone pain Bone pain x x
Alanine aminotransferase increased Alanine aminotransferase increased x
Drug tolerance decreased Decreased tolerance x
Scab Scab x
Visual acuity reduced Visual acuity reduced x
Eye irritation Eye irritation x
Visual impairment Visual disturbance x
Lip dry Lip dry x x
Febrile neutropenia Febrile neutropenia x
Hepatitis F Hepatitis F x
Cataract subcapsular Posterior subcapsular cataract x
Liver function test abnormal Raised liver function tests x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Acitretin capsules / Neotigason, Capsule

Side effects:40
Source:Medsafe

Acitretin

Side effects:67
Source:BC Cancer

ACITRETIN / SORIATANE

Side effects:130
Source:Health Canada

ACITRETIN

Side effects:184
Source:FDA Structured Product Label

ACITRETIN

Side effects:186
Source:FDA Structured Product Label

ACITRETIN

Side effects:187
Source:FDA Structured Product Label

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label