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Vincristine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01CA02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4
Nausea Nausea 52% x x x x
Infection Infection 39.8% x
Diarrhoea Diarrhoea 37% x x x x
Decreased appetite Decreased appetite 33% x
Anorexia x x x
Neuropathy peripheral Neuropathy 32.5% x x
Neuropathy peripheral 10% - 39% x
Insomnia Insomnia 32% x x
Febrile neutropenia Febrile neutropenia 20.5% - 38% x
Constipation Constipation 4.82% - 57% x x x x
Asthenia Fatigue 12% - 41% x
Asthenia 4.82% x
Fatigue Fatigue 12% - 41% x
Anaemia Anaemia 16.9% - 34% x x x x
Gastrointestinal disorder Gastrointestinal disorder 25.3% x
Mediastinal disorder Mediastinal disorder 20.5% x
Neutropenia Neutropenia 18.1% x
Thrombocytopenia Thrombocytopenia 16.9% x x x
Neuritis Peripheral motor neuropathy 16.9% x
Peripheral motor neuropathy Peripheral motor neuropathy 16.9% x
Body temperature increased Body temperature increased 13.3% - 43% x x x x
Mental disorder Mental disorder 10.8% x
Cardiac disorder Cardiac disorder 10.8% x
Angiopathy Angiopathy 9.64% x
Abdominal pain Abdominal pain 8.43% x
Abdominal cramps x x x
Abdominal colic x x x
Gastrointestinal pain Abdominal pain 8.43% x
Connective tissue disorder Connective tissue disorder 8.43% x
Pain Pain 8.43% x x x x
Pneumonia Pneumonia 8.43% x
Urethral disorder Urinary tract disorder 7.23% x
Urinary tract disorder Urinary tract disorder 7.23% x
Aspartate aminotransferase increased Aspartate aminotransferase increased 7.23% x
Hypotension Hypotension 6.02% - 7.2% x x x x
Colonic pseudo-obstruction Colonic pseudo-obstruction 6.02% x
Septic shock Septic shock 6.02% x
Staphylococcal bacteraemia Staphylococcal bacteraemia 6.02% x
Ileus Ileus 6.02% x x x x
Cardiac arrest Cardiac arrest 6% - 6.02% x
Respiratory distress Respiratory distress 6% - 6.02% x
Respiratory failure Respiratory failure 4.82% x
Mental status changes Mental status changes 3.61% x
Tumour lysis syndrome Tumour lysis syndrome 2% x
Muscular weakness Muscular weakness 1.2% x
Acute abdomen Acute abdomen x x x
Adrenal disorder Adrenal disorder x x x
Alopecia Alopecia x x x
Anaphylactic shock Anaphylactic shock x x x
Ataxia Ataxia x x x
Back pain Back pain x x x
Coma Coma x x x
Dehydration Dehydration x x x
Depression Depression x
Dizziness Dizziness x x
Dysuria Dysuria x x x
Oedema Oedema x x x
Dermatitis Rash x x x
Rash Rash x x x
Extravasation Extravasation x
VIIth nerve paralysis Facial paralysis x
Hallucination Hallucination x
Headache Headache x x x
Venoocclusive liver disease Venoocclusive liver disease x
Hypersensitivity Hypersensitivity x
Hypertension Hypertension x x x
Hyponatraemia Hyponatraemia x x x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion x
Intestinal obstruction Intestinal obstruction x
Leukaemia Leukaemia x
Leukopenia Leukopenia x x
Multi-organ failure Multi-organ failure x
Muscle atrophy Muscle atrophy x x
Musculoskeletal pain Musculoskeletal pain x
Myocardial infarction Myocardial infarction x x x
Acute coronary syndrome Myocardial infarction x x x
Myoclonus Myoclonus x
Nervous system disorder Nervous system disorder x
Hypoaesthesia Numbness x
Sensory loss Numbness x
Sensory loss x x
Nystagmus Nystagmus x x
Optic atrophy Optic atrophy x x x
Pain in extremity Pain in extremity x x x
Ileus paralytic Ileus paralytic x x x
Paresis Paresis x x
Paraesthesia Paraesthesia x x
Polyuria Polyuria x x x
Urine output increased Polyuria x x x
Convulsion Convulsion x x x
Stomatitis Stomatitis x
Mouth ulceration x x x
Hyperhidrosis Sweating x
Vertigo Vertigo x x
Vocal cord paralysis Vocal cord paralysis x x
Vomiting Vomiting x x x
Weight decreased Weight decreased x x x
Urinary retention Urinary retention x x x
Sudden cardiac death Sudden cardiac death x
Hepatic failure Hepatic failure x
Agitation Agitation x
Peroneal nerve palsy Footdrop x x x
Mouth ulceration Mouth ulceration x x x
Cranial nerve paralysis Cranial nerve paralysis x
Pulmonary haemorrhage Pulmonary haemorrhage x
Pancytopenia Bone marrow depression x x
Myelosuppression x
Bone pain Bone pain x x x
Hyporeflexia Hyporeflexia x
Blindness cortical Blindness cortical x x x
Photosensitivity reaction Photosensitivity reaction x
Myalgia Myalgia x x x
Musculoskeletal discomfort Myalgia x x x
Altered state of consciousness Consciousness abnormal x
Neurotoxicity Neurotoxicity x
Pain in jaw Pain in jaw x x x
Erectile dysfunction Erectile dysfunction x
Azotaemia Azotaemia x x x
Walking disability Walking disability x x
Gait disturbance Walking disability x x
Atonic urinary bladder Atonic urinary bladder x x x
Menorrhagia Prolonged menses x x
Blindness Blindness x x
Paralysis Paralysis x x x
Deafness Complete hearing loss x x
Drug interaction Drug interaction x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Cerebral infarction Brain infarction x
Urine sodium increased Urine sodium increased x
Decreased vibratory sense Decreased vibratory sense x
Coronary artery disease Coronary artery disease x x x
Gastrointestinal necrosis Intestinal necrosis x x x
Cerebral haemorrhage Cerebral haemorrhage x
Urate nephropathy Urate nephropathy x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Vincristine

Side effects:52
Source:FDA Structured Product Label

Vincristine Sulfate / Oncovin®

Side effects:60
Source:FDA

VINCRISTINE

Side effects:64
Source:FDA Structured Product Label

Vincristine Sulfate / Name of drug

Side effects:65
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label